Association between long-term prescription of febuxostat and the progression of heart failure with preserved ejection fraction in patients with hypertension and asymptomatic hyperuricemia.

abstract：:Atrial fibrillation (AF) is a complex disease with multiple inter-relating causes culminating in rapid atrial activation and atrial structural remodeling. The contribution of endoplasmic reticulum and mitochondria stress to AF has been highlighted. As the class III antiarrhythmic agent, ibutilide are widely used to AF...

journal_title：Heart and vessels

authors： Wang Y,Wang YL,Huang X,Yang Y,Zhao YJ,Wei CX,Zhao M

更新日期：2017-02-01 00:00:00

abstract：:It is well known that silent myocardial ischemia (SMI) often complicates patients with cerebral infarction and that stroke patients often die of ischemic heart disease. Therefore, it is considered important to treat myocardial ischemia in stroke patients. This study investigated SMI complicating Japanese patients with...

journal_title：Heart and vessels

authors： Nomura T,Kusaba T,Kodama N,Terada K,Urakabe Y,Nishikawa S,Keira N,Matsubara H,Tatsumi T

更新日期：2013-01-01 00:00:00

abstract：:Lamotrigine has been used for patients with epilepsy and/or bipolar disorder, overdose of which induced the hypotension, elevation of the atrial pacing threshold, cardiac conduction delay, wide complex tachycardia, cardiac arrest and Brugada-like electrocardiographic pattern. To clarify how lamotrigine induces those c...

journal_title：Heart and vessels

authors： Goto A,Hagiwara-Nagasawa M,Kambayashi R,Nunoi Y,Izumi-Nakaseko H,Kawai S,Takei Y,Matsumoto A,Sugiyama A

更新日期：2020-11-02 00:00:00

abstract：:Myocardial fibrosis and microvascular dysfunction are key determinants of outcome in heart failure (HF); we examined their relationship in patients with HF. Our study included 61 consecutive patients with HF but without coronary stenosis. All underwent gadolinium-enhanced cardiac magnetic resonance to evaluate late ga...

journal_title：Heart and vessels

authors： Uemura T,Yamamuro M,Kaikita K,Takashio S,Utsunomiya D,Hirakawa K,Nakayama M,Sakamoto K,Yamamoto E,Tsujita K,Kojima S,Hokimoto S,Yamashita Y,Ogawa H

更新日期：2016-12-01 00:00:00

abstract：:The purpose was to study optimum timing of continuous veno-venous hemodialysis (CVVHD) for acute renal failure (ARF) after cardiac surgery. CVVHD was performed in two groups [elapsed time between urine output (UO) <0.5 ml/kg/h and dialysis of no more than 12 h in group A and >12 h in group B] with a total of 58 adult ...

journal_title：Heart and vessels

authors： Ji Q,Mei Y,Wang X,Feng J,Cai J,Zhou Y,Sun Y,Xie S,Hu D

更新日期：2011-03-01 00:00:00

abstract：:Previous studies have reported the prognostic value of objective nutritional indices such as the Controlling Nutritional Status (CONUT) score, Geriatric Nutritional Risk Index (GNRI) and Prognostic Nutritional Index (PNI). However, the effects of these indices in patients with coronary artery disease (CAD) who have un...

journal_title：Heart and vessels

authors： Wada H,Dohi T,Miyauchi K,Endo H,Tsuboi S,Ogita M,Kasai T,Okazaki S,Isoda K,Suwa S,Daida H

更新日期：2018-12-01 00:00:00

abstract：:Morphological and functional changes of free arterial grafts in dogs were studied for 3 weeks after implantation and the changes were compared to those in implanted free vein grafts. In the arterial grafts, endothelial cells with abundant pinocytotic vesicles and some cytoplasmic folds were observed by transmission an...

journal_title：Heart and vessels

authors： Isomura T,Hisatomi K,Inuzuka H,Nishimi M,Hirano A,Ohishi K

更新日期：1992-01-01 00:00:00

abstract：:Chronic kidney disease (CKD) is well known to be associated with an increased incidence of coronary artery disease (CAD). Diabetes mellitus (DM) and hypertension (HTN), both of which are traditional risk factors for CAD, are the two most common causes of CKD. However, the influence of CKD on coronary atherosclerosis i...

journal_title：Heart and vessels

authors： Shigemoto E,Iwata A,Futami M,Kato Y,Yamashita M,Imaizumi S,Kuwano T,Ike A,Sugihara M,Saku K,Miura SI

更新日期：2019-07-01 00:00:00

abstract：:Eicosapentaenoic acid (EPA), a member of the omega-3 polyunsaturated fatty acid family, prevents cardiovascular disease. C-reactive protein (CRP) is a marker of inflammation, which promotes atherosclerosis. The aim of this study was to investigate the relationship among EPA, CRP, and the prevalence of peripheral arter...

journal_title：Heart and vessels

authors： Sugiura T,Yoshikawa D,Ishii H,Suzuki S,Kumagai S,Inoue Y,Okumura S,Isobe S,Hayashi M,Ando H,Amano T,Murohara T

更新日期：2014-07-01 00:00:00

abstract：:Cross-sectional data suggest that the degree of coronary atherosclerosis is associated with aerobic fitness. However, there are limited longitudinal data addressing whether aerobic fitness is a predictor of coronary atherosclerosis progression. This study investigated whether peak oxygen consumption is related to a lo...

journal_title：Heart and vessels

authors： Sung J,Cho SJ,Choe YH,Yoo S,Woo KG,Choi YH,Hong KP

更新日期：2016-09-01 00:00:00

abstract：:Although a previous randomized study showed that the use of atrial natriuretic peptide (carperitide) improved the long-term prognosis of patients with heart failure, its effect on short-term prognosis remains unclear. We retrospectively identified patients who were admitted to our tertiary-care center with acute decom...

journal_title：Heart and vessels

authors： Ogiso M,Isogai T,Okabe Y,Ito K,Tsuji M,Tanaka H

更新日期：2017-08-01 00:00:00

abstract：:The number of circulating endothelial progenitor cells (EPCs) is considered to be a surrogate marker for coronary artery disease (CAD). Recent studies have identified a novel T-cell subset labeled with CD3(+)/CD31(+), which is necessary for EPC colony formation and constitutes the central cluster. However, the clinica...

journal_title：Heart and vessels

authors： Kakizaki M,Nobori K,Watanabe H,Iino K,Ishida M,Ito H

更新日期：2013-09-01 00:00:00

abstract：:Whether trough-phase rivaroxaban concentrations provide sufficient anticoagulation needs more study. We evaluated levels of coagulation activation markers in the trough concentration phase in nonvalvular atrial fibrillation (NVAF) patients, and the correlation between these markers and rivaroxaban concentration. Fifty...

journal_title：Heart and vessels

authors： Kitagawa F,Ishii J,Hiramitsu S,Takahashi H,Okuyama R,Kawai H,Muramatsu T,Harada M,Motoyama S,Naruse H,Matsui S,Sarai M,Hayashi M,Watanabe E,Izawa H,Ozaki Y

更新日期：2017-05-01 00:00:00

abstract：:A 70-year-old man underwent stent implantation for right coronary artery (RCA) lesions with a bare metal stent (BMS) and two sirolimus-eluting stents (SES). However, as both the BMS and SES stented sites developed restenosis after 13 months, he underwent target lesion revascularization using directional coronary ather...

journal_title：Heart and vessels

authors： Nasuno T,Tokura M,Kageyama M,Toyoda S,Sakuma M,Komatsu T,Taguchi I,Abe S,Inoue T

更新日期：2016-06-01 00:00:00

abstract：:Hypertrophic cardiomyopathy (HCM) with severe diastolic dysfunction is a major cause of heart failure and sudden cardiac death (SCD) associated with lethal arrhythmia. Although various risk factors for cardiac events have been reported in HCM patients, previous studies have reported that some HCM patients exhibit eith...

journal_title：Heart and vessels

authors： Sugiura Y,Morimoto R,Aoki S,Yamaguchi S,Haga T,Kuwayama T,Yokoi T,Hiraiwa H,Kondo T,Watanabe N,Kano N,Fukaya K,Sawamura A,Okumura T,Murohara T

更新日期：2019-12-01 00:00:00

abstract：:The aim of our study was to assess the atherosclerotic burden in patients with the first symptoms of coronary artery disease (CAD). The study population consisted of 100 consecutive patients (new-onset severe angina or myocardial infarction) and 70 age- and sex-matched volunteers without symptoms of CAD. Functional an...

journal_title：Heart and vessels

authors： Cerne A,Kranjec I

更新日期：2002-09-01 00:00:00

abstract：:T cells are involved in the pathogenesis of atherosclerosis. We aimed to search for any association between the peripheral T-cell activities and atherogenic risk factors in healthy subjects. Fifty male volunteers (age 22.0 +/- 2.4 years) were enrolled. No subject had any chronic disease or was under any drug treatment...

journal_title：Heart and vessels

authors： Sonmez A,Kisa U,Uckaya G,Eyileten T,Kinalp C,Yilmaz MI,Dogru T,Turan M,Kocar IH

更新日期：2006-07-01 00:00:00

abstract：:The purpose of this study was to examine the histopathological findings of right ventricular endomyocardial biopsies from ten patients less than 60 years of age (47 +/- 9.8 (mean +/- SD) years) with documented atrioventricular block but without apparent heart disease. They underwent electrophysiological testing, echoc...

journal_title：Heart and vessels

authors： Teragaki M,Toda I,Sakamoto K,Shimada K,Yamagishi H,Yoshiyama M,Akioka K,Kawase Y,Nishimoto M,Takeuchi K,Yoshikawa J

更新日期：1999-01-01 00:00:00

abstract：:The subendocardial side of myocardium makes a major contribution to left ventricular (LV) contraction and is very susceptible to ischemia. In this study we sought to quantify regional wall motion during low-dose dobutamine stress echocardiography (DSE) by using the myocardial velocity gradient (MVG) derived from tissu...

journal_title：Heart and vessels

authors： Tsutsui H,Uematsu M,Yamagishi M,Haruta S,Shimakura T,Miyatake K

更新日期：2000-01-01 00:00:00

abstract：:Predictors of outcomes in patients with heart failure with preserved left-ventricular ejection fraction (HFpEF) remain unclear. The ratio of early diastolic transmitral flow velocity to early diastolic myocardial velocity (E/e') has been proposed, but the predictive accuracy remains unsatisfactory. We hypothesized tha...

journal_title：Heart and vessels

authors： Kanda T,Uematsu M,Fujita M,Iida O,Masuda M,Okamoto S,Ishihara T,Nanto K,Tsujimura T,Matsuda Y,Okuno S,Mano T

更新日期：2018-12-01 00:00:00

abstract：:The objectives of the study were to evaluate the impact of aortic angulation (AA) on success of transcatheter aortic valve replacement (TAVR) with a new generation self-expandable prosthesis (Medtronic Evolut R®). Specific anatomical conditions, such as for example the presence of a horizontal aorta with elevated AA, ...

journal_title：Heart and vessels

authors： D'Ancona G,Kische S,El-Mawardy M,Dißmann M,Heinze H,Zohlnhöfer-Momm D,Gürer H,Ince H

更新日期：2019-12-01 00:00:00

abstract：:This study investigates the interactions between cyclooxygenase (COX-2) and vascular smooth muscle cell (VSMC) phenotypic switching, the two important coupling mechanisms of the vasculature on arterial remodeling in response to high laminal shear stress. High aortic blood flow was induced by creating a fistula in the ...

journal_title：Heart and vessels

authors： Roan JN,Tsai YC,Chen IW,Chang SW,Huang CC,Lam CF

更新日期：2012-05-01 00:00:00

abstract：:Compared to the general population, elderly patients with cardiovascular disease have a higher prevalence of sarcopenia, and it shows an association with increased mortality risk. Although several studies have indicated that atherosclerosis may cause sarcopenia in community dwelling elderly subjects, the association b...

journal_title：Heart and vessels

authors： Uchida S,Kamiya K,Hamazaki N,Matsuzawa R,Nozaki K,Ichikawa T,Suzuki Y,Nakamura T,Yamashita M,Kariya H,Maekawa E,Yamaoka-Tojo M,Matsunaga A,Ako J

更新日期：2020-06-01 00:00:00

abstract：:The purpose of this study was to examine factors influencing readmission to hospital in patients with heart failure. This multicenter, retrospective cohort study analyzed 197 heart failure patients admitted to the research cooperation facilities between January 2017 and November 2017. We defined the readmission group ...

journal_title：Heart and vessels

authors： Umehara T,Katayama N,Tsunematsu M,Kakehashi M

更新日期：2020-03-01 00:00:00

abstract：:Treatment with inhibitors of 3-hydroxyl-3-methylglutaryl coenzyme A reductase (statins) reduces the incidence of cardiovascular events, but it is unclear whether the beneficial effects are mediated solely by their lipid-lowering properties. We therefore investigated whether atorvastatin reduces inflammation and oxidat...

journal_title：Heart and vessels

authors： Sugiyama M,Ohashi M,Takase H,Sato K,Ueda R,Dohi Y

更新日期：2005-07-01 00:00:00

abstract：:We clarified that the set of the isotropic component (T) of wall tension and the area (A) of a selected region of the left ventricular wall expresses the regional work with sufficient accuracy. The area surrounded by the locus of the T-A relation in the T-A plane is approximately equal to the real work done by that re...

journal_title：Heart and vessels

authors： Sugawara M,Tamiya K,Nakano K

更新日期：1985-08-01 00:00:00

abstract：:Acute kidney injury (AKI) is a common complication after coronary angiography. Early biomarkers of this disease are needed since increase in serum creatinine levels is a late marker. To assess the usefulness of urinary kidney injury molecule-1 (uKIM-1), neutrophil gelatinase-associated lipocalin (uNGAL) and liver-type...

journal_title：Heart and vessels

authors： Torregrosa I,Montoliu C,Urios A,Andrés-Costa MJ,Giménez-Garzó C,Juan I,Puchades MJ,Blasco ML,Carratalá A,Sanjuán R,Miguel A

更新日期：2015-11-01 00:00:00

abstract：:Direct oral anticoagulants (DOACs), such as rivaroxaban, reduce the risk of stroke and systemic embolism in patients with nonvalvular atrial fibrillation (NVAF). However, it is still unclear whether the stroke reduction benefit outweighs the bleeding risk in elderly Japanese patients with NVAF. The Xarelto Post-Author...

journal_title：Heart and vessels

authors： Kitazono T,Ikeda T,Ogawa S,Nakagawara J,Minematsu K,Miyamoto S,Murakawa Y,Cavaliere M,Hayashi Y,Kidani Y,Okayama Y,Sunaya T,Sato S,Yamanaka S

更新日期：2020-03-01 00:00:00

abstract：:Sensitive cardiac troponin I (cTnI) predicts all-cause and cardiovascular mortality in various clinical settings. However, its clinical significance in hemodialysis (HD) patients with preserved left ventricular ejection fraction (LVEF) has not been fully elucidated. This study investigated the association of cTnI with...

journal_title：Heart and vessels

authors： Otsuka K,Nakanishi K,Shimada K,Nakamura H,Inanami H,Nishioka H,Fujimoto K,Kasayuki N,Yoshiyama M

更新日期：2018-11-01 00:00:00

abstract：:Blood traces tortuous paths of flow through the heart. We postulate that momentum changes associated with direction changes optimize dynamic coupling between ventricular and atrial function, particularly on exercise. Traces of pulsed Doppler mitral flow and M-mode long-axis mitral ring movement were recorded before an...

journal_title：Heart and vessels

authors： Kilner PJ,Henein MY,Gibson DG

更新日期：1997-01-01 00:00:00