Abstract:
:The purpose of this study was to examine the histopathological findings of right ventricular endomyocardial biopsies from ten patients less than 60 years of age (47 +/- 9.8 (mean +/- SD) years) with documented atrioventricular block but without apparent heart disease. They underwent electrophysiological testing, echocardiography, coronary angiography, and right ventricular endomyocardial biopsy. Biopsy specimens were assessed for morphologic changes in myocyte diameter, fibrosis, disarray, and degeneration. Electrophysiological testing demonstrated atrioventricular nodal block in 2, intra-His bundle block in 2, and infra-His bundle block in 6 patients. Histology revealed evidence of myocardial fibrosis with either myocyte hypertrophy or disarray in 7 of the 10 patients. The results of electrophysiological testing did not correlate with the histopathological findings or severity. In one patient, heart failure appeared during the follow-up period. We conclude that patients with atrioventricular block of unknown etiology have histological abnormalities of the ventricular endomyocardium in addition to the conduction system disturbances. We consider such cases as constituting one of the disease groups of cardiomyopathy, and suggest that it is necessary to follow up the clinical course in these patients.
journal_name
Heart Vesselsjournal_title
Heart and vesselsauthors
Teragaki M,Toda I,Sakamoto K,Shimada K,Yamagishi H,Yoshiyama M,Akioka K,Kawase Y,Nishimoto M,Takeuchi K,Yoshikawa Jdoi
10.1007/BF02482303subject
Has Abstractpub_date
1999-01-01 00:00:00pages
170-6issue
4eissn
0910-8327issn
1615-2573journal_volume
14pub_type
杂志文章abstract::Abnormal P-wave characteristics were reportedly associated with left ventricular interstitial fibrosis as defined by cardiac magnetic resonance images. The objective of this study is to investigate the utility of P-wave characteristics to predict atrial fibrillation (AF) recurrence and the recovery of left ventricular...
journal_title:Heart and vessels
pub_type: 杂志文章
doi:10.1007/s00380-018-1179-4
更新日期:2018-11-01 00:00:00
abstract::There are few studies regarding the assessment of left ventricular contractile function in patients with atrial fibrillation (AF). The aim of this study was to assess the left ventricular (LV) contractile function, i.e., the end-systolic pressure-volume relation (Ees) and a recently developed LV systolic myocardial st...
journal_title:Heart and vessels
pub_type: 临床试验,杂志文章
doi:10.1007/BF01744589
更新日期:1998-01-01 00:00:00
abstract::Subclavian artery stenosis can cause a flow reversal-so-called steal-not only in the ipsilateral vertebral artery, but also in the internal mammary artery in patients with a history of coronary-artery bypass grafting. Subclavian artery stenosis is also associated with peripheral artery disease elsewhere. We report a n...
journal_title:Heart and vessels
pub_type: 杂志文章
doi:10.1007/s00380-016-0821-2
更新日期:2016-11-01 00:00:00
abstract::Pulmonary arterial hypertension (PAH) is characterized by a progressive increase in pulmonary arterial pressure and vascular resistance. Despite advances in therapy for PAH, its treatment and prognosis remain poor. We aimed to investigate whether the transplantation of bone marrow mesenchymal stem cells (MSCs) overexp...
journal_title:Heart and vessels
pub_type: 杂志文章
doi:10.1007/s00380-013-0395-1
更新日期:2014-07-01 00:00:00
abstract::A drawback of visual assessment for late gadolinium enhancement (LGE) on cardiac magnetic resonance (CMR) is the subjectivity and reproducibility of the results. The aim of this study was to investigate the relationship between left ventricular (LV) reverse remodeling in response to optimal pharmacotherapies and the d...
journal_title:Heart and vessels
pub_type: 杂志文章
doi:10.1007/s00380-018-1196-3
更新日期:2018-12-01 00:00:00
abstract::To assess left ventricular diastolic properties in response to dynamic exercise, mitral inflow velocity integrals were measured by pulsed-wave Doppler echocardiography in ten patients with myocardial infarction and in ten normal subjects, and simultaneous left ventricular pressure was obtained with micromanometry in t...
journal_title:Heart and vessels
pub_type: 杂志文章
doi:
更新日期:1993-01-01 00:00:00
abstract::To define mechanisms that may influence collateral circulation and angiogenesis, we investigated vascular endothelial growth factor (VEGF) mRNA expression in human hearts. In non-ischemic human hearts, VEGF mRNA was not detected in vessels, but was found in cardiomyocytes. In hearts with myocardial infarction, the int...
journal_title:Heart and vessels
pub_type: 杂志文章
doi:10.1007/BF01745169
更新日期:1996-01-01 00:00:00
abstract::Cardiac systolic (left ventricular ejection fraction) and diastolic (mitral inflow velocity pattern and/or mitral deceleration time) function were reported as predictors of clinical outcome or left ventricular remodeling in patients with acute myocardial infarction (AMI). Recently, a new index (Doppler-derived index c...
journal_title:Heart and vessels
pub_type: 杂志文章
doi:10.1007/s00380-003-0735-7
更新日期:2004-03-01 00:00:00
abstract::Mechanical hemolysis after transcatheter occlusion of the patent ductus arteriosus using the Rashkind umbrella device has been postulated as a rare, but serious complication, even necessitating surgical repair. A rare, case of an adult patient with massive hemolytic anemia, successfully controlled by the combined use ...
journal_title:Heart and vessels
pub_type: 杂志文章
doi:10.1007/BF01747502
更新日期:1997-01-01 00:00:00
abstract::Phrenic nerve (PN) stimulation is essential for the elimination of PN palsy during balloon-based pulmonary vein isolation (PVI). Although ultrasound-guided vascular access is safe, insertion of a PN stimulation catheter via central venous access carries a potential risk of the development of mechanical complications. ...
journal_title:Heart and vessels
pub_type: 杂志文章
doi:10.1007/s00380-019-01402-4
更新日期:2019-10-01 00:00:00
abstract::Acute kidney injury (AKI) is a common complication after coronary angiography. Early biomarkers of this disease are needed since increase in serum creatinine levels is a late marker. To assess the usefulness of urinary kidney injury molecule-1 (uKIM-1), neutrophil gelatinase-associated lipocalin (uNGAL) and liver-type...
journal_title:Heart and vessels
pub_type: 杂志文章
doi:10.1007/s00380-014-0538-z
更新日期:2015-11-01 00:00:00
abstract::In addition to plaque rupture (PR), calcified nodule (CN) may also have the potential to develop into arterial thrombus in the peripheral arteries. This study evaluated the distribution of plaque ruptures and calcified nodules in the peripheral arteries and their impact on the outcome of endovascular therapy (EVT). Co...
journal_title:Heart and vessels
pub_type: 杂志文章
doi:10.1007/s00380-017-0984-5
更新日期:2017-10-01 00:00:00
abstract::The records of 153 patients with doubly committed subarterial ventricular septal defect (DCVSD) who underwent intracardiac repair were analyzed to evaluate factors responsible for aortic valve leaflet deformity. The patients were divided into two groups according to their echocardiographic and angiographic features as...
journal_title:Heart and vessels
pub_type: 杂志文章
doi:10.1007/BF01747853
更新日期:1999-01-01 00:00:00
abstract::The progression of cardiac hypertrophy and failure is associated with marked changes in cardiac autonomic innervation, and there are sympathetic-parasympathetic interactions in the regulation of cardiac function. Although the indexes of sympathetic innervation have been found to be depressed with the development of he...
journal_title:Heart and vessels
pub_type: 杂志文章
doi:10.1007/BF02058280
更新日期:1991-01-01 00:00:00
abstract::During left nephrectomy in a 35-year-old woman with a left renal cell carcinoma extending into the inferior vena cava (IVC) and right atrium, cardiac arrest occurred. Immediate transesophageal echocardiography demonstrated that the event was caused by a pulmonary tumor embolism. Emergent cardiopulmonary bypass (CPB) w...
journal_title:Heart and vessels
pub_type: 杂志文章
doi:10.1007/BF02767048
更新日期:1997-01-01 00:00:00
abstract::Studies have demonstrated that thyroid hormone (T3) can precondition the heart against ischaemic injury and improve post-ischaemic recovery. This study investigated whether the AT2 receptor (AT2R) is involved in cardioprotection and the potential molecular mechanism responsible for this effect. Hyperthyroidism was ind...
journal_title:Heart and vessels
pub_type: 杂志文章
doi:10.1007/s00380-017-1101-5
更新日期:2018-06-01 00:00:00
abstract::Based on the unique property of fluorine-18 fluorodeoxyglucose, localization and follow-up of hypermetabolic processes is possible with positron emission tomography (PET). The dual-modality PET/computed tomography (CT) systems provide intrinsically fused morphologic and functional data in a single examination. We repo...
journal_title:Heart and vessels
pub_type: 杂志文章
doi:10.1007/s00380-004-0808-2
更新日期:2005-07-01 00:00:00
abstract::Vascular smooth muscle cell (VSMC) differentiation and phenotypic modulation are characterized by changes in gene expression for smooth muscle (SM) marker contractile proteins such as SM alpha-actin and SM22alpha. Hyperplasia suppressor gene (HSG) is a potent VSMC proliferation-inhibiting factor; however, it is not kn...
journal_title:Heart and vessels
pub_type: 杂志文章
doi:10.1007/s00380-006-0914-4
更新日期:2006-09-01 00:00:00
abstract::Aortic valve stenosis (AS) is a frequent complication contributing to poor prognosis in chronic hemodialysis (CHD) patients. High blood pressure (BP) is known to be associated with AS progression in the general population. In CHD patients, however, BP varies during and between hemodialysis sessions with ultrafiltratio...
journal_title:Heart and vessels
pub_type: 杂志文章
doi:10.1007/s00380-015-0756-z
更新日期:2016-09-01 00:00:00
abstract::The purpose of this study was to evaluate the surgical results of papillary muscle approximation (PMA) and papillary muscle relocation (PMR) for functional mitral regurgitation (FMR) and to compare the effects of both procedures on the change in mitral regurgitation (MR) and echocardiogram parameters associated with t...
journal_title:Heart and vessels
pub_type: 杂志文章
doi:10.1007/s00380-017-1038-8
更新日期:2018-01-01 00:00:00
abstract::Right atrial pressure (RAP), a representative parameter of right heart failure, is very important for prognostic evaluation and risk assessment in pulmonary hypertension. However, its measurement requires invasive cardiac catheterization. In this study, we determined the most accurate echocardiographic surrogate of ca...
journal_title:Heart and vessels
pub_type: 杂志文章
doi:10.1007/s00380-018-1264-8
更新日期:2019-03-01 00:00:00
abstract::Percutaneous transvenous mitral commissurotomy (PTMC) increases peak oxygen uptake (VO2) chronically, but not acutely, despite early symptomatic improvements. Analysis of transient VO2 responses to submaximal exercise (an exercise regimen more comparable to the patients' daily activities than that provided by maximal ...
journal_title:Heart and vessels
pub_type: 杂志文章
doi:10.1007/BF02911391
更新日期:1995-01-01 00:00:00
abstract::Due to the complex profile of atherosclerotic risk factors, an integrated analysis of a specific individual is difficult. Endothelial function reflects a composite of various risk factors, and may be used as an optimal tool to estimate the overall atherosclerotic risk. In this study, we investigated the value of digit...
journal_title:Heart and vessels
pub_type: 杂志文章
doi:10.1007/s00380-018-1118-4
更新日期:2018-07-01 00:00:00
abstract::It is known that the heart of an athlete has been physiologically adapted by prolonged training. There are a large number of echocardiographic studies which have focused on left ventricular wall thickness and dilatation, but there are few studies concerning right heart function in the athlete's heart. The aim of this ...
journal_title:Heart and vessels
pub_type: 杂志文章
doi:10.1007/s003800200018
更新日期:2002-07-01 00:00:00
abstract::Scanning electron microscopy was used to compare the shape, size, and connection of left ventricular (LV) myocytes between spontaneously hypertensive rats (SHR) and Wistar Kyoto rats (WKY) at 3, 8, 15, 35, and 63 weeks of age. For either strain at each age, five rats were studied, in which LV myocytes consisted of a c...
journal_title:Heart and vessels
pub_type: 杂志文章
doi:10.1007/BF02481739
更新日期:1999-01-01 00:00:00
abstract::An excess of thyroid hormone is known to produce cardiac dysfunction and failure, i.e., thyrotoxic heart. We studied the protective effect of coenzyme Q10 (CoQ10) on the thyrotoxic heart in 29 rabbits. A group treated with 1-thyroxine sodium salt (T4; 167 micrograms/kg) for 3 weeks showed marked decreases in the myoca...
journal_title:Heart and vessels
pub_type: 杂志文章
doi:10.1007/BF02058524
更新日期:1987-01-01 00:00:00
abstract::Sex-related factors play an important role in the pathophysiology of heart failure (HF). However, trends in sex-related differences in hospital management for HF are not clear. We identified patients hospitalized for HF through a nationwide database (National Health Insurance in Taiwan), containing 722,272 subjects fr...
journal_title:Heart and vessels
pub_type: 杂志文章
doi:10.1007/s00380-012-0299-5
更新日期:2013-11-01 00:00:00
abstract::Aberrant coronary arteries are frequently observed in patients presenting with Fallot's tetralogy (TOF). Before the complete surgical repair of the TOF, the percutaneously performed pulmonary trunk (PT) angioplasty is often performed in order to temporarily increase the pulmonary circulation, thus increasing the pulmo...
journal_title:Heart and vessels
pub_type: 杂志文章
doi:10.1007/s00380-007-1023-8
更新日期:2008-03-01 00:00:00
abstract::Although endothelial progenitor cells (EPCs) are considered to be an essential source of vascular endothelial repair, their bidirectional differentiation determines that they play a double-edged role in the restoration of endothelial injury. In this research, we investigated the effect of Kir2.1 ion channel on the tra...
journal_title:Heart and vessels
pub_type: 杂志文章
doi:10.1007/s00380-020-01625-w
更新日期:2020-10-01 00:00:00
abstract::Independent no-reflow predictors should be evaluated in female patients with ST-segment elevation acute myocardial infarction (STEMI) and successfully treated with primary percutaneous coronary intervention (PPCI) in the current interventional equipment and techniques, thus to be constructed a no-reflow predicting mod...
journal_title:Heart and vessels
pub_type: 杂志文章,多中心研究
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更新日期:2012-05-01 00:00:00