Inhibition of cyclooxygenase-2 modulates phenotypic switching of vascular smooth muscle cells during increased aortic blood flow.

abstract：:Amiodarone is a highly effective antiarrhythmic agent. Unfortunately amiodarone-induced pulmonary toxicity is described for medium-long term therapy. We describe a case of a 65-year-old man admitted to our department for breathlessness and with a history of recurrent episodes of atrial fibrillation for which he had be...

journal_title：Heart and vessels

authors： Benassi F,Molardi A,Righi E,Santangelo R,Meli M

更新日期：2015-05-01 00:00:00

abstract：:Although the ultimate cause for the myocardial dysfunction of hypertensive heart disease is still unclear, a crucial role of the myocardial energy metabolism has been suggested. Therefore, the aim of the present study was to investigate whether age-related myocardial dysfunction in hearts of spontaneously hypertensive...

journal_title：Heart and vessels

authors： Perings SM,Schulze K,Decking U,Kelm M,Strauer BE

更新日期：2000-01-01 00:00:00

abstract：:The distribution and structure of lymphatic and blood capillaries in the rabbit heart conduction system were investigated by transmission electron microscopy. The sinuatrial node, atrioventricular node, and atrioventricular bundle possessed a rich network of lymphatic capillaries, which were situated not only at the p...

journal_title：Heart and vessels

authors： Shimada T,Noguchi T,Kitamura H,Matsufuji Y,Campbell GR

更新日期：1988-01-01 00:00:00

abstract：:Although the number of pregnancies in women with cardiac disease is increasing worldwide, there are few data concerning their clinical characteristics and peripartum outcomes. Using the Diagnosis Procedure Combination database between 2008 and 2014 in Japan, we retrospectively identified pregnant women who underwent h...

journal_title：Heart and vessels

authors： Isogai T,Matsui H,Tanaka H,Kohyama A,Fushimi K,Yasunaga H

更新日期：2018-08-01 00:00:00

abstract：:A 53-year-old woman with end-stage renal disease and hypertension, who had received regular artificial hemodialysis for 10 years, has been treated with candesartan in a dose of 8 mg/day against her hypertension, but premature ventricular contractions were often observed during the hemodialysis. QT interval was 445 ms ...

journal_title：Heart and vessels

authors： Cao X,Nakamura Y,Wada T,Izumi-Nakaseko H,Ando K,Sugiyama A

更新日期：2017-01-01 00:00:00

abstract：:Myocardial fibrosis and microvascular dysfunction are key determinants of outcome in heart failure (HF); we examined their relationship in patients with HF. Our study included 61 consecutive patients with HF but without coronary stenosis. All underwent gadolinium-enhanced cardiac magnetic resonance to evaluate late ga...

journal_title：Heart and vessels

authors： Uemura T,Yamamuro M,Kaikita K,Takashio S,Utsunomiya D,Hirakawa K,Nakayama M,Sakamoto K,Yamamoto E,Tsujita K,Kojima S,Hokimoto S,Yamashita Y,Ogawa H

更新日期：2016-12-01 00:00:00

abstract：:Levels of testosterone and estradiol influence the incidence of cardiovascular diseases: generally, estrogens in females are protective before menopause; coronaropathies, hypertension, and dyslipidemias in normal men are more frequent at comparable ages. We investigated the modulation by castration of in vitro vasorea...

journal_title：Heart and vessels

authors： Perez I,El Hafidi M,Carvajal K,Baños G

更新日期：2009-03-01 00:00:00

abstract：:To define mechanisms that may influence collateral circulation and angiogenesis, we investigated vascular endothelial growth factor (VEGF) mRNA expression in human hearts. In non-ischemic human hearts, VEGF mRNA was not detected in vessels, but was found in cardiomyocytes. In hearts with myocardial infarction, the int...

journal_title：Heart and vessels

authors： Shinohara K,Shinohara T,Mochizuki N,Mochizuki Y,Sawa H,Kohya T,Fujita M,Fujioka Y,Kitabatake A,Nagashima K

更新日期：1996-01-01 00:00:00

abstract：:Intracellular Na(+) ([Na(+)](i)) regulation plays a crucial role in the structural, mechanical, and electrical properties of myocardium. It is assumed that the [Na(+)](i) handling system may differ not only between normal and diseased hearts but also regionally within a heart. To gain new insight concerning disease- a...

journal_title：Heart and vessels

authors： Yamamoto T,Shirayama T,Takahashi T,Matsubara H

更新日期：2009-01-01 00:00:00

abstract：:Early and long-term outcomes in elderly patients who underwent isolated aortic valve replacement (iAVR) are well defined. Conflicting data exist in elderly patients who underwent AVR plus coronary artery bypass grafting (CABG). We sought to evaluate the early and long-term outcomes of combined AVR + CABG in patients o...

journal_title：Heart and vessels

authors： Formica F,Mariani S,D'Alessandro S,Singh G,Di Mauro M,Cerrito MG,Messina LA,Scianna S,Papesso F,Sangalli F

更新日期：2020-04-01 00:00:00

abstract：:Therapeutic devices for acute myocardial infarction (AMI) have evolved dramatically in recent years. However, the impact of the Killip classification of AMI outcomes in patients undergoing aggressive percutaneous coronary intervention remains unclear. We performed a 10-year retrospective review of 2062 patients diagno...

journal_title：Heart and vessels

authors： Taguchi E,Konami Y,Inoue M,Suzuyama H,Kodama K,Yoshida M,Miyamoto S,Nakao K,Sakamoto T

更新日期：2017-12-01 00:00:00

abstract：:Peripheral artery disease (PAD) is a risk factor for the development of heart failure and mortality. The serum levels of carboxy-terminal telopeptide of type I collagen (I-CTP), a marker for collagen degradation derived from the extracellular matrix of vascular and myocardial tissue, is reportedly a useful marker for ...

journal_title：Heart and vessels

authors： Otaki Y,Watanabe T,Takahashi H,Yamaura G,Nishiyama S,Arimoto T,Shishido T,Miyamoto T,Kubota I

更新日期：2017-02-01 00:00:00

abstract：:It is known that the heart of an athlete has been physiologically adapted by prolonged training. There are a large number of echocardiographic studies which have focused on left ventricular wall thickness and dilatation, but there are few studies concerning right heart function in the athlete's heart. The aim of this ...

journal_title：Heart and vessels

authors： Erol MK,Karakelleoglu S

更新日期：2002-07-01 00:00:00

abstract：:Coronary artery spasm is involved in the pathogenesis of various cardiac disorders. We investigated patients with a history of syncope who underwent elective coronary angiography. We retrospectively analyzed 5781 consecutive patients who had diagnostic or follow-up angiography during a 26-year period. During this peri...

journal_title：Heart and vessels

authors： Sueda S,Kohno H

更新日期：2018-02-01 00:00:00

abstract：:T cells are involved in the pathogenesis of atherosclerosis. We aimed to search for any association between the peripheral T-cell activities and atherogenic risk factors in healthy subjects. Fifty male volunteers (age 22.0 +/- 2.4 years) were enrolled. No subject had any chronic disease or was under any drug treatment...

journal_title：Heart and vessels

authors： Sonmez A,Kisa U,Uckaya G,Eyileten T,Kinalp C,Yilmaz MI,Dogru T,Turan M,Kocar IH

更新日期：2006-07-01 00:00:00

abstract：:In addition to plaque rupture (PR), calcified nodule (CN) may also have the potential to develop into arterial thrombus in the peripheral arteries. This study evaluated the distribution of plaque ruptures and calcified nodules in the peripheral arteries and their impact on the outcome of endovascular therapy (EVT). Co...

journal_title：Heart and vessels

authors： Horimatsu T,Fujii K,Fukunaga M,Miki K,Nishimura M,Naito Y,Shibuya M,Imanaka T,Kawai K,Tamaru H,Sumiyoshi A,Saita T,Masuyama T,Ishihara M

更新日期：2017-10-01 00:00:00

abstract：:Both hypertension and hyperuricemia are closely associated with the morbidity and mortality of heart failure. This study was designed to evaluate the influences of long-term xanthine oxidase inhibitor (febuxostat) prescription on left ventricular hypertrophy (LVH), left ventricular (LV) diastolic function, and new-ons...

journal_title：Heart and vessels

authors： Pan JA,Lin H,Wang CQ,Zhang JF,Gu J

更新日期：2020-10-01 00:00:00

abstract：:The normal development of elastin fibers in the thoracic aorta was studied in fetal, young, and adult monkeys. Tissue was examined by scanning electron microscopy (SEM) after NaOH treatment and by transmission electron microscopy (TEM). The NaOH treatment of fixed tissues effectively removed collagen fibers and enable...

journal_title：Heart and vessels

authors： Sato F,Shimada T,Kitamura H,Campbell GR,Ogata J

更新日期：1994-01-01 00:00:00

abstract：:Cross-sectional data suggest that the degree of coronary atherosclerosis is associated with aerobic fitness. However, there are limited longitudinal data addressing whether aerobic fitness is a predictor of coronary atherosclerosis progression. This study investigated whether peak oxygen consumption is related to a lo...

journal_title：Heart and vessels

authors： Sung J,Cho SJ,Choe YH,Yoo S,Woo KG,Choi YH,Hong KP

更新日期：2016-09-01 00:00:00

abstract：:Coronary slow flow (CSF) is characterized by delayed opacification of coronary arteries in the absence epicardial occlusive disease. QT duration and dispersion have been reported to be longer in patients with CSF. ACE inhibitors may improve CSF through positive effects on endothelial function. The study included 32 pa...

journal_title：Heart and vessels

authors： Guntekin U,Gumrukcuoglu HA,Gunes Y,Gunes A,Simsek H,Sahin M,Sezen Y,Akdağ S,Tuncer M

更新日期：2011-07-01 00:00:00

abstract：:Thin-cap fibroatheroma (TCFA) is the most common type of vulnerable plaque and is the precursor of plaque rupture. However, rupture of a TCFA is not the only mechanism underlying thrombus formation or acute coronary syndrome. Although statin therapy changes the composition of coronary artery plaques, the effects of st...

journal_title：Heart and vessels

authors： Nozue T,Yamamoto S,Tohyama S,Fukui K,Umezawa S,Onishi Y,Kunishima T,Sato A,Nozato T,Miyake S,Takeyama Y,Morino Y,Yamauchi T,Muramatsu T,Hibi K,Terashima M,Michishita I

更新日期：2015-01-01 00:00:00

abstract：:Electrocardiographic left ventricular hypertrophy (ECG-LVH) gradually regressed after aortic valve replacement (AVR) in patients with severe aortic stenosis. Sokolow-Lyon voltage (SV1 + RV5/6) is possibly the most widely used criterion for ECG-LVH. The aim of this study was to determine whether decrease in Sokolow-Lyo...

journal_title：Heart and vessels

authors： Yamabe S,Dohi Y,Higashi A,Kinoshita H,Sada Y,Hidaka T,Kurisu S,Shiode N,Kihara Y,HERO (Hiroshima Heart Study Group) Investigators.

更新日期：2016-09-01 00:00:00

abstract：:We analyzed whether smoking was associated with major adverse cardiovascular events (MACE) and the progression of coronary atherosclerosis as assessed by coronary computed tomography angiography (CCTA) as screening for coronary artery disease (CAD). We enrolled 443 patients who had all undergone CCTA and either were c...

journal_title：Heart and vessels

authors： Higashi S,Shiga Y,Yano M,Imaizumi T,Tashiro K,Idemoto Y,Kato Y,Kuwano T,Sugihara M,Miura SI

更新日期：2020-11-27 00:00:00

abstract：:Vascular calcification is an ectopic calcification that commonly occurs in atherosclerosis. Because taurine was previously shown to protect against cardiovascular diseases, the effect of taurine on vascular calcification was evaluated in calcified vascular smooth muscle cells (VSMCs) of rat in vitro in the present stu...

journal_title：Heart and vessels

authors： Li J,Zhang B,Huang Z,Wang S,Tang C,Du J

更新日期：2004-05-01 00:00:00

abstract：:Periprocedural bleeding and thromboembolic events are worrisome complications of catheter ablation for atrial fibrillation (AF). Periprocedural anticoagulation management could decrease the risk of these complications. However, evaluation of the complications from pulmonary vein isolation using cryoballoon related to ...

journal_title：Heart and vessels

authors： Ando M,Inden Y,Yoshida Y,Sairaku A,Yanagisawa S,Suzuki H,Watanabe R,Takenaka M,Maeda M,Murohara T

更新日期：2019-09-01 00:00:00

abstract：:The association between periprocedural hypotension and conscious sedation (CS) during defibrillator implantation remains to be elucidated. The aim of the present study was to compare the occurrence of periprocedural hypotension after CS or local anesthesia (LA) during defibrillator implantation in a retrospective coho...

journal_title：Heart and vessels

authors： Ugata Y,Michihata N,Matsui H,Fushimi K,Yasunaga H

更新日期：2020-01-01 00:00:00

abstract：:Chronic inflammation has received a great deal of attention due to the role it plays in cardiovascular disease (CVD). The cardio-ankle vascular index (CAVI) has recently been developed to evaluate arterial stiffness. This index is independent of blood pressure at the time that it is measured, making it a better measur...

journal_title：Heart and vessels

authors： Kotani K,Yamada T,Miyamoto M,Kario K,Ishibashi S,Taniguchi N

更新日期：2012-09-01 00:00:00

abstract：:Abnormal P-wave characteristics were reportedly associated with left ventricular interstitial fibrosis as defined by cardiac magnetic resonance images. The objective of this study is to investigate the utility of P-wave characteristics to predict atrial fibrillation (AF) recurrence and the recovery of left ventricular...

journal_title：Heart and vessels

authors： Doi A,Takagi M,Katayama H,Yoshiyama T,Hayashi Y,Tatsumi H,Yoshiyama M

更新日期：2018-11-01 00:00:00

abstract：:Activation of mineralocorticoid receptor antagonists (MRAs) is cardioprotective; however, this property is lost upon blockade or inactivation of adenosine (ADO) receptor A2b. In this study, we investigated whether the effects of MRAs are mediated by an interaction between cardioprotective ADO receptors A1 and A3. Spir...

journal_title：Heart and vessels

authors： Hermidorff MM,de Assis LVM,Rodrigues JA,Soares LL,Andrade MHG,Natali AJ,Isoldi MC

更新日期：2020-05-01 00:00:00

abstract：:Wave intensity (WI) is a new hemodynamic index, which is defined as (dP/dt)(dU/dt) at any site of the circulation, where dP/dt and dU/dt are the time derivatives of blood pressure and velocity, respectively. Arterial WI in normal subjects has two positive sharp peaks. The first peak occurs during early systole when a ...

journal_title：Heart and vessels

authors： Niki K,Sugawara M,Uchida K,Tanaka R,Tanimoto K,Imamura H,Sakomura Y,Ishizuka N,Koyanagi H,Kasanuki H

更新日期：1999-01-01 00:00:00