Abnormalities of cervical arteries in children with arterial ischemic stroke.

abstract：OBJECTIVES:Deep brain stimulation of the internal pallidum (GPi-DBS) is an established therapeutic option in treatment-refractory dystonia, and the identification of factors predicting surgical outcome is needed to optimize patient selection. METHODS:In this retrospective multicenter study, GPi-DBS outcome of 8 patien...

journal_title：Neurology

authors： Brüggemann N,Kühn A,Schneider SA,Kamm C,Wolters A,Krause P,Moro E,Steigerwald F,Wittstock M,Tronnier V,Lozano AM,Hamani C,Poon YY,Zittel S,Wächter T,Deuschl G,Krüger R,Kupsch A,Münchau A,Lohmann K,Volkmann J,Kle

更新日期：2015-03-03 00:00:00

abstract：OBJECTIVE:To characterize presenting symptomatology in patients with semantic dementia (SD) and to investigate whether left and right temporal variants of the disease have distinct behavioral and cognitive profiles. METHODS:Retrospective examination of case notes was performed in 47 consecutive referrals of patients w...

journal_title：Neurology

authors： Thompson SA,Patterson K,Hodges JR

更新日期：2003-11-11 00:00:00

abstract：:Migraine is associated with stimulus hypersensitivity, increased evoked cortical responses, and abnormal 5-HT levels in peripheral blood. We studied cortical auditory evoked potentials (AEPs) between attacks in 35 patients suffering from migraine without aura (MO, n = 25) or with aura (MA, n = 10) and in 25 healthy vo...

journal_title：Neurology

authors： Wang W,Timsit-Berthier M,Schoenen J

更新日期：1996-05-01 00:00:00

abstract：OBJECTIVE:Coccidioides species are the most common etiologic agents of chronic meningitis in regions endemic for coccidioidomycosis. Occasionally, even short-term travel to endemic regions results in the acquisition of meningeal disease, so awareness of this complication of coccidioidomycosis is important even in nonen...

journal_title：Neurology

authors： Drake KW,Adam RD

更新日期：2009-11-24 00:00:00

abstract：:A 61-year-old woman presented with two paraneoplastic neurologic disorders--Lambert-Eaton myasthenic syndrome (LEMS) and subacute cerebellar degeneration (SCD)--that antedated the diagnosis of small-cell carcinoma of the lung by 15 months. Plasmapheresis initiated before the identification of the tumor had a beneficia...

journal_title：Neurology

authors： Blumenfeld AM,Recht LD,Chad DA,DeGirolami U,Griffin T,Jaeckle KA

更新日期：1991-10-01 00:00:00

abstract：OBJECTIVE:To use the large dataset from the Tysabri Outreach: Unified Commitment to Health (TOUCH) program to compare progressive multifocal leukoencephalopathy (PML) risk with natalizumab extended interval dosing (EID) vs standard interval dosing (SID) in patients with multiple sclerosis (MS). METHODS:This retrospect...

journal_title：Neurology

authors： Ryerson LZ,Foley J,Chang I,Kister I,Cutter G,Metzger RR,Goldberg JD,Li X,Riddle E,Smirnakis K,Kasliwal R,Ren Z,Hotermans C,Ho PR,Campbell N

更新日期：2019-10-08 00:00:00

abstract：BACKGROUND:Over 50% of persons with idiopathic REM sleep behavior disorder (RBD) will develop Parkinson disease (PD) or dementia. At present, there is no way to predict who will develop disease. Since polysomnography is performed in all patients with idiopathic RBD at diagnosis, there is an opportunity to analyze if ba...

journal_title：Neurology

authors： Postuma RB,Gagnon JF,Rompré S,Montplaisir JY

更新日期：2010-01-19 00:00:00

abstract：:The effects of lysine vasopressin on memory and cognitive deficits in Alzheimer disease was investigated. In a double-blind study, seven patients were given 16 units of lysine vasopressin per day for 10 days and were compared with seven different patients receiving placebo. No significant difference in performance bet...

journal_title：Neurology

authors： Durso R,Fedio P,Brouwers P,Cox C,Martin AJ,Ruggieri SA,Tamminga CA,Chase TN

更新日期：1982-06-01 00:00:00

abstract：:We measured the cerebral metabolic rate for glucose (CMRglc) with positron emission tomography and [18F]2-fluoro-2-deoxy-D-glucose in a 47-year-old man with trisomy 21 Down's syndrome (DS) and autopsy-confirmed Alzheimer's disease. Dementia was evident from a confirmed history of cognitive decline, memory loss, and pe...

journal_title：Neurology

authors： Schapiro MB,Ball MJ,Grady CL,Haxby JV,Kaye JA,Rapoport SI

更新日期：1988-06-01 00:00:00

abstract：:Although a neuromuscular syndrome has been induced experimentally by vitamin E deficiency, a human syndrome has not yet been documented. This report describes a 7-year-old boy with severe malabsorption since birth who presented with progressive external ophthalmoplegia, proximal muscle weakness, peripheral neuropathy,...

journal_title：Neurology

authors： Tomasi LG

更新日期：1979-08-01 00:00:00

abstract：OBJECTIVE:To identify independent predictors of clinical or cerebral lesion progression in a large sample of adult patients with moyamoya angiopathy (MMA) prior to decisions regarding revascularization surgery. METHODS:Ninety participants (median age, 37.5 years) were assessed at baseline and followed for a median tim...

journal_title：Neurology

authors： Hervé D,Ibos-Augé N,Calvière L,Rogan C,Labeyrie MA,Guichard JP,Godin O,Kossorotoff M,Habert MO,Lasserve ET,Chevret S,Chabriat H

更新日期：2019-07-23 00:00:00

abstract：:We enrolled 11 patients with secondary progressive MS in a randomized single-masked cross-over study of plasma exchange (PE) in combination with azathioprine 2 mg/kg. PE was performed once a week for 4 weeks and thereafter every second week for 20 weeks (14 treatments). Eight patients completed the whole trial, and th...

journal_title：Neurology

authors： Sørensen PS,Wanscher B,Szpirt W,Jensen CV,Ravnborg M,Christiansen P,Schreiber K,Nordenbo A

更新日期：1996-06-01 00:00:00

abstract：OBJECTIVE:We sought cognitive event-related potential (ERP) biomarkers of disease progression and subsequent conversion to dementia in mild cognitive impairment (MCI). BACKGROUND:Two ERP components, the P600 and N400, are sensitive to abnormal episodic/declarative memory and semantic processing. When congruous categor...

journal_title：Neurology

authors： Olichney JM,Taylor JR,Gatherwright J,Salmon DP,Bressler AJ,Kutas M,Iragui-Madoz VJ

更新日期：2008-05-06 00:00:00

abstract：OBJECTIVE:To describe a clinical syndrome of cerebellar ataxia associated with muscle coenzyme Q10 (CoQ10) deficiency. BACKGROUND:Muscle CoQ10 deficiency has been reported only in a few patients with a mitochondrial encephalomyopathy characterized by 1) recurrent myoglobinuria; 2) brain involvement (seizures, ataxia, ...

journal_title：Neurology

authors： Musumeci O,Naini A,Slonim AE,Skavin N,Hadjigeorgiou GL,Krawiecki N,Weissman BM,Tsao CY,Mendell JR,Shanske S,De Vivo DC,Hirano M,DiMauro S

更新日期：2001-04-10 00:00:00

abstract：OBJECTIVE:To measure white matter (WM) and gray matter (GM) atrophy and lesion load in a large population of patients with multiple sclerosis (MS) using a fully automated, operator-independent, multiparametric segmentation method. METHODS:The study population consisted of 597 patients with MS and 104 control subjects....

journal_title：Neurology

authors： Tedeschi G,Lavorgna L,Russo P,Prinster A,Dinacci D,Savettieri G,Quattrone A,Livrea P,Messina C,Reggio A,Bresciamorra V,Orefice G,Paciello M,Brunetti A,Coniglio G,Bonavita S,Di Costanzo A,Bellacosa A,Valentino P,Quar

更新日期：2005-07-26 00:00:00

abstract：BACKGROUND:There are no published MRI studies comparing interferon beta 1b (IFNbeta-1b) and glatiramer acetate (GA) for treatment of relapsing multiple sclerosis (MS). OBJECTIVE:To compare the efficacy of IFNbeta-1b and GA for suppression of MS disease activity as evidenced on frequent brain MRI. METHODS:A total of 7...

journal_title：Neurology

authors： Cadavid D,Wolansky LJ,Skurnick J,Lincoln J,Cheriyan J,Szczepanowski K,Kamin SS,Pachner AR,Halper J,Cook SD

更新日期：2009-06-09 00:00:00

abstract：OBJECTIVE:We investigated if tau, microtubular binding protein, in serum and ventricular CSF (vCSF) in patients with severe traumatic brain injury (TBI) during the initial posttraumatic days correlated to 1-year outcome. METHODS:Patients with severe TBI (n = 39, Glasgow Coma Scale score

journal_title：Neurology

authors： Ost M,Nylén K,Csajbok L,Ohrfelt AO,Tullberg M,Wikkelsö C,Nellgård P,Rosengren L,Blennow K,Nellgård B

更新日期：2006-11-14 00:00:00

abstract：:Dapsone produces a potentially reversible toxic neuropathy, with its primary effect on the soma and axons of motor neurons as opposed to myelin. There is very little evidence to suggest involvement of sensory axons in most cases; if present, it would appear minimal. A "dying back" of motor axons is postulated to produ...

journal_title：Neurology

authors： Gutmann L,Martin JD,Welton W

更新日期：1976-06-01 00:00:00

abstract：OBJECTIVE:The natural history of succinic semialdehyde dehydrogenase (SSADH) deficiency in adulthood is unknown; we elucidate the clinical manifestations of the disease later in life. METHODS:A 63-year-old man with long-standing intellectual disability was diagnosed with SSADH deficiency following hospitalization for ...

journal_title：Neurology

authors： Lapalme-Remis S,Lewis EC,De Meulemeester C,Chakraborty P,Gibson KM,Torres C,Guberman A,Salomons GS,Jakobs C,Ali-Ridha A,Parviz M,Pearl PL

更新日期：2015-09-08 00:00:00

abstract：:Human subjects normally have miniature eye movements during tasks that require steady visual fixation. These eye movements were compared in 12 control subjects and 4 patients with degenerative cerebellar disorders. Slow drifts, small fixation saccades, square waves, saccadic oscillations, flutter, and vertical nystagm...

journal_title：Neurology

authors： Hotson JR

更新日期：1982-01-01 00:00:00

abstract：:We report of a woman aged 52 years born to consanguineous parents and seeking treatment for progressive dementia and delusion. Neurologic examination revealed dementia and emotional instability, indifference, and confabulation. There was also mild spasticity of the bilateral lower limbs. MRI revealed diffuse white mat...

journal_title：Neurology

authors： Ohtake H,Shimohata T,Terajima K,Kimura T,Jo R,Kaseda R,Iizuka O,Takano M,Akaiwa Y,Goto H,Kobayashi H,Sugai T,Muratake T,Hosoki T,Shioiri T,Okamoto K,Onodera O,Tanaka K,Someya T,Nakada T,Tsuji S

更新日期：2004-05-11 00:00:00

abstract：BACKGROUND:Infection with HIV can result in a debilitating CNS disorder known as HIV dementia (HIV-D). Since the advent of highly active antiretroviral therapy (HAART), the incidence of HIV-D has declined, but the prevalence continues to increase. In this new era of HIV-D, traditional biomarkers such as CSF viral load ...

journal_title：Neurology

authors： Bandaru VV,McArthur JC,Sacktor N,Cutler RG,Knapp EL,Mattson MP,Haughey NJ

更新日期：2007-05-01 00:00:00

abstract：:Proton nuclear magnetic resonance spectroscopy is a noninvasive technique allowing the localized, in vivo detection of proton-containing brain metabolites. We used this technique to study eight patients with cerebral infarction or ischemia. A stimulated echo-pulse sequence with chemical shift imaging was used to acqui...

journal_title：Neurology

authors： Ford CC,Griffey RH,Matwiyoff NA,Rosenberg GA

更新日期：1992-07-01 00:00:00

abstract：:Antibodies to myelin-associated glycoprotein (MAG) are found in patients with both monoclonal gammopathy and sensorimotor peripheral neuropathy but almost never in patients with amyotrophic lateral sclerosis (ALS). Ninety percent of patients with anti-MAG activity also have antibodies to sulfated glucuronic acid parag...

journal_title：Neurology

authors： Rowland LP,Sherman WL,Hays AP,Lange DJ,Latov N,Trojaborg W,Younger DS

更新日期：1995-04-01 00:00:00

abstract：:We used proton magnetic resonance spectroscopy (1H MRS) to investigate the temporal lobes of 25 patients with temporal lobe epilepsy. Spectra were obtained from 2 x 2 x 2 cm cubes in the medial region of the temporal lobe, and were analyzed on the basis of signals from N-acetylaspartate (NAA), creatine + phosphocreati...

journal_title：Neurology

authors： Connelly A,Jackson GD,Duncan JS,King MD,Gadian DG

更新日期：1994-08-01 00:00:00

abstract：:Trigeminal neuralgia is an uncommon but troublesome symptom of multiple sclerosis that can be refractory to conventional treatments. Misoprostol, a long-acting prostaglandin E1 analogue, relieved pain in six of seven patients who had failed to respond to conventional pharmacologic therapy. ...

journal_title：Neurology

authors： Reder AT,Arnason BG

更新日期：1995-06-01 00:00:00

abstract：:A 25-year-old woman with Kearns-Sayre syndrome (KSS) had complete external ophthalmoplegia, short stature, ataxia, cardiac conduction defects, and pigmentary retinopathy. Muscle biopsy revealed ragged-red fibers. Electron microscopy showed increased numbers of mitochondria with disordered structure and paracrystalline...

journal_title：Neurology

authors： Rivner MH,Shamsnia M,Swift TR,Trefz J,Roesel RA,Carter AL,Yanamura W,Hommes FA

更新日期：1989-05-01 00:00:00

abstract：OBJECTIVE:To quantify the associations of peripapillary retinal nerve fiber layer (pRNFL) thickness and macular ganglion cell layer (mGCL) volume with cognitive functioning and to investigate how demographic and vascular health factors affect these associations in a population-based sample of adults. METHODS:The sampl...

journal_title：Neurology

authors： Ward DD,Mauschitz MM,Bönniger MM,Merten N,Finger RP,Breteler MMB

更新日期：2020-09-01 00:00:00

abstract：OBJECTIVE:To empirically validate the expanded concept of mild cognitive impairment (MCI), which differentiates between four clinical subtypes-amnestic MCI-single domain, amnestic MCI-multiple domains, nonamnestic MCI-single domain, and nonamnestic MCI-multiple domains-and to examine the prevalence, course, and outcome...

journal_title：Neurology

authors： Busse A,Hensel A,Gühne U,Angermeyer MC,Riedel-Heller SG

更新日期：2006-12-26 00:00:00

abstract：OBJECTIVE:To evaluate attention deficit in Alzheimer's disease (AD) and its relationship to attention deficits associated with aging and with medications altering alertness. METHODS:Ten patients with probable AD, 10 healthy old controls, and 15 young controls performed a covert orienting of spatial attention task. You...

journal_title：Neurology

authors： Oken BS,Kishiyama SS,Kaye JA,Howieson DB

更新日期：1994-04-01 00:00:00