Isolation and identification of sapotexanthin 5,6-epoxide and 5,8-epoxide from red mamey (Pouteria sapota).

abstract：:The impact of crystalline forces on the solid-state circular dichroism (CD) spectrum of hypothemycin (), a biologically active molecule extracted from natural sources, has been analyzed by means of time-dependent density functional theory CD calculations. Input structures were extracted from the X-ray geometry of and ...

journal_title：Chirality

authors： Pescitelli G

更新日期：2012-09-01 00:00:00

abstract：:Enantiomers of chiral aliphatic hydrocarbons are generally difficult to separate because they lack functional groups to be derivatized in order to generate diastereomers. The systematic and quantitative separation of a series of branched hydrocarbon enantiomers using a chiral cyclodextrin stationary phase and a cryost...

journal_title：Chirality

authors： Meierhenrich UJ,Nguyen MJ,Barbier B,Brack A,Thiemann WH

更新日期：2003-01-01 00:00:00

abstract：:Conditions for separation of enantiomers of a mandelic acid derivative, methyl 2-phenyl-2-(tetrahydropyranyloxy) acetate (the analyte) were studied. Because of the presence of two chiral carbons, the analyte consists of four stereoisomers stable at ambient temperature. Chiral HPLC of the analyte resulted in four peaks...

journal_title：Chirality

authors： Shen B,Xu X,Chen J,Zhang X,Xu B

更新日期：2006-09-01 00:00:00

abstract：:(S)-(-)-2-(α-hydroxyethyl)-benzimidazole and (S)-(+)-2-(α-hydroxybenzyl)-benzimidazole work as chiral Brønsted bases (BBs) in Diels-Alder reaction between anthrone and maleimides under mild reaction condition. These chiral BBs cause asymmetric induction. ...

journal_title：Chirality

authors： Mirgane NA,Karnik AV

更新日期：2011-05-01 00:00:00

abstract：:Hornet silks adopt a variety of morphology such as fibers, sponge, films, and gels depending on the preparation methods. We have studied the conformation change of hornet silk proteins (Vespa mandarina) as regenerated films, using chiroptical spectrophotometer universal chiroptical spectrophotometer 1, which can measu...

journal_title：Chirality

authors： Kuroda R,Kameda T

更新日期：2018-05-01 00:00:00

abstract：:The binding of the title benzodiazepine enantiomers and its modulation by warfarin and bilirubin were studied by chromatography on human serum albumin (HSA) immobilized on Sepharose 4B, and also by a combination of ultrafiltration and circular dichroism (UF-CD) methods. In the absence of warfarin and bilirubin the bin...

journal_title：Chirality

authors： Fitos I,Visy J,Magyar A,Kajtár J,Simonyi M

更新日期：1990-01-01 00:00:00

abstract：:We demonstrate by using vibrational circular dichroism (VCD) spectroscopy that it is possible to investigate the chirality of a supramolecular polymeric system in relatively dilute solutions. Chiral C(3)-symmetrical discotic molecules, based on a trialkylbenzene-1,3,5-carboxamide, form supramolecular columnar stacks w...

journal_title：Chirality

authors： Smulders MM,Buffeteau T,Cavagnat D,Wolffs M,Schenning AP,Meijer EW

更新日期：2008-09-01 00:00:00

abstract：:A three-dimensional molecularly imprinted overoxidized polypyrrole/MnO2 /carbon felt (MIOPPy/MnO2 /CF) composites were fabricated, which results in increased active area of the surface of the molecularly imprinted polymers film and greatly improved electrochemical chiral recognition effect for tryptophan isomers. The ...

journal_title：Chirality

authors： Dong L,Liu X,Xu H,Wu D,Gao S,Zhong L,Kong Y

更新日期：2019-11-01 00:00:00

abstract：:Six enantiomeric pairs of TADDOL-s gathered in two series with either methyl (series A) or phenyl (series B) substituent in 2-position of the dioxolane ring were studied by vibrational circular dichroism (VCD). Experimental IR and VCD spectra associated with density functional theory (DFT) calculations showed that the...

journal_title：Chirality

authors： Uncuta C,Bartha E,Gherase D,Teodorescu F,Draghici C,Cavagnat D,Daugey N,Liotard D,Buffeteau T

更新日期：2010-01-01 00:00:00

abstract：:The direct asymmetric aldol reactions of equivalent molar amounts of aldehydes and ketones were carried out at -20 degrees C over alkaline Al(2)O(3) with 20 mol % of Pro-Trp as catalyst and 20 mol % of N-methylmorpholine or 1,4-diazabicyclo[2.2.2]octane as additive. After simple and environmentally friendly work-up, m...

journal_title：Chirality

authors： Lei M,Xia S,Wang J,Ge Z,Cheng T,Li R

更新日期：2010-06-01 00:00:00

abstract：:The phenomenon of enantioselectivity in the metabolism of mexiletine (MEX) conjugation was investigated in eight female patients with the arrhythmic form of chronic Chagas' heart disease treated with racemic mexiletine hydrochloride (two 100 mg capsules every 8 hr). Blood samples were collected up to 24 hr after the a...

journal_title：Chirality

authors： Lanchote VL,Cesarino EJ,Santos VJ,Mere Júnior Y,Santos SR

更新日期：1999-01-01 00:00:00

abstract：:Previously, a diazaphospholidine has been synthesized and evaluated as a chiral derivatizing reagent for the determination of the optical purity of chiral alcohols via 31P NMR spectroscopy (Alexakis et al., J. Org. Chem. 57:1224-1237, 1992). Our laboratory is interested in the advantageous and practical applications o...

journal_title：Chirality

authors： House KL,O'Connor MJ,Silks LA 3rd,Dunlap RB,Odom JD

更新日期：1994-01-01 00:00:00

abstract：:The perturbation of the racemic equilibrium of luminescent D3 terbium(III) complexes with chelidamic acid (CDA), a hydroxylated derivative of 2,6-pyridine-dicarboxylic acid (DPA), by added chiral biomolecules such as L-amino acids has been studied using circularly polarized luminescence and 13C NMR spectroscopy. It is...

journal_title：Chirality

authors： Moussa A,Pham C,Bommireddy S,Muller G

更新日期：2009-05-01 00:00:00

abstract：:The chiral separation by counter-current chromatography has made great progress in the past three decades. It has become increasingly popular in the field of chiral separation, and many applications have been introduced during the last years. This review mainly focuses on the current topics, applications, and trends i...

journal_title：Chirality

authors： Duan WD,Huang XY,Di DL

更新日期：2020-10-01 00:00:00

abstract：:The R enantiomers of some of the 2-arylpropionic acid non-steroidal antiinflammatory drugs (NSAIDs) are known to undergo metabolic chiral inversion to their more pharmacologically active antipodes. This process is drug and species dependent and usually unidirectional. The S to R chiral inversion, on the other hand, is...

journal_title：Chirality

authors： Jamali F,Lovlin R,Aberg G

更新日期：1997-01-01 00:00:00

abstract：:1,1,1,3,3-pentafluoro-2-(fluoromethoxy)-3-methoxypropane, compound B, is a product obtained in the degradation of the anesthetic Sevoflurane. Enantiopure (+)-B was investigated using vibrational circular dichroism (VCD). Experimental absorption and VCD spectra of (+)-B in CDCl(3) solution in the 2,000-900 cm(-1) regio...

journal_title：Chirality

authors： Wang F,Polavarapu PL,Schurig V,Schmidt R

更新日期：2002-08-01 00:00:00

abstract：:High-performance liquid chromatography (HPLC) is a powerful method in the area of chiral separation. In this study, a method of HPLC using carboxymethyl-β-cyclodextrin (CM-β-CD) as chiral selector was developed for enantioseparation of nine indanone and tetralone derivatives. The separation was performed on a conventi...

journal_title：Chirality

authors： Hu X,Guo X,Sun S,Zhu B,Yu J,Guo X

更新日期：2017-01-01 00:00:00

abstract：:Racemic 1-phenylethylamine was optically resolved by its own derivative formed with glutaric acid namely (+)-(R)-N-(1-phenylethyl)glutaramic acid. The amide acid resolving agent was synthesized from (+)-(R)-1-phenylethylamine by N-derivatization. The glutaric acid derivative was the next in a homologous series of dica...

journal_title：Chirality

authors： Schindler J,Egressy M,Bereczki L,Pokol G,Fogassy E,Marthi K

更新日期：2007-03-01 00:00:00

abstract：:The pharmacokinetics of (-)-N-(trans-4-isopropylcyclohexanecarbonyl)-D-phenylalanine (nateglinide) and its enantiomer (L-enantiomer) was studied in Goto-Kakizaki (GK) rats after intravenous administration of nateglinide or L-enantiomer at a dose of 40 micromol/kg body weight. Nateglinide, its L-enantiomer and their me...

journal_title：Chirality

authors： Tamura M,Shiba S,Kudo N,Kawashima Y

更新日期：2010-01-01 00:00:00

abstract：:Homoprolinol analogs, a class of optically active γ-amino alcohols, were examined systematically in the enantioselective addition reactions of diethylzinc to aldehydes. By comparison of the results catalyzed by these γ-amino alcohols with those by the β-amino alcohols based on pyrrolidine architecture reported in the ...

journal_title：Chirality

authors： Liu CL,Wei CY,Wang SW,Peng YG

更新日期：2011-11-01 00:00:00

abstract：:The simultaneous disposition of fenoprofen enantiomers in synovial fluid and plasma was studied in 11 patients with arthritis and chronic knee effusions treated with a single oral dose of 600 mg rac-fenoprofen. A plasma sample and a synovial fluid sample were collected simultaneously from each patient up to 16 h after...

journal_title：Chirality

authors： De Miranda Silva C,Marques MP,Barissa GR,Donadi EA,Da Silva LM,Lanchote VL

更新日期：2007-05-05 00:00:00

abstract：:Stereoselectivity in the renal secretion of carbenicillin (CBPC) was studied in rabbits. Significant renal secretion of CBPC was observed in vivo, with the secretion of the S-epimer being greater than that of the R-epimer. Stereoselective transport of CBPC was further studied in vitro using basolateral and brush borde...

journal_title：Chirality

authors： Itoh T,Nakaura H,Koyano S,Tsuda Y,Yamada H

更新日期：1998-01-01 00:00:00

abstract：:In the presence of tridentate chiral ligand 4e, 99% e.e. value was obtained by asymmetric reduction of ethyl benzoylacetate with borane in toluene at 25 degrees C. Various ligands and reaction conditions were investigated to develop a reasonable mechanism that explains the experimental outcomes. ...

journal_title：Chirality

authors： Lee DS

更新日期：2007-02-01 00:00:00

abstract：:In this review, the recently reported approaches for the preparation of cyclodextrin-functionalized capillary monolithic columns are highlighted, with few applications in chiral separations using capillary liquid chromatography (CLC) and capillary electrochromatography (CEC). Chirality 28:97-109, 2016. © 2015 Wiley Pe...

journal_title：Chirality

authors： Adly FG,Antwi NY,Ghanem A

更新日期：2016-02-01 00:00:00

abstract：:2-Alkenyl- and 2-vinyl-5-pyrimidyl alkanols are highly enantioselective asymmetric autocatalysts with significant amplification of enantiomeric excess in the enantioselective addition of diisopropylzinc to 2-alkenyl- and 2-vinylpyrimidine-5-carbaldehydes. Consecutive asymmetric autocatalysis starting from 7% ee increa...

journal_title：Chirality

authors： Sato I,Yanagi T,Soai K

更新日期：2002-02-01 00:00:00

abstract：:An increase in both retention and enantioselectivity for some beta-blocking agents was observed when exchanging potassium to sodium ion in the buffer used as mobile phase. A large effect of ionic strength on retention was observed, while the enantioselectivity was constant. ...

journal_title：Chirality

authors： Hedeland M,Jönsson S,Isaksson R,Pettersson C

更新日期：1998-01-01 00:00:00

abstract：:Little is known about the stereochemistry of sulfation of chiral phenolic drugs. In this study we examined several in vitro approaches to this question, using (+)-, (-)-, or (+/-)-terbutaline as the substrate and the rat liver cytosol as the phenolsulfotransferase enzyme source. The cosubstrate PAPS was either generat...

journal_title：Chirality

authors： Walle UK,Walle T

更新日期：1989-01-01 00:00:00

abstract：:Planar 2(5H)-furanones substituted at C4 with a chiral pyrrolidinyl group show CD spectra which are apparently due to the distortion of the C4-N1 bond of sp2 character from the plane defined by the 2(5H)-furanone ring atoms and/or due to the presence of substituents in the pyrrolidine ring. This is a new, previously n...

journal_title：Chirality

authors： Gawroński J,Gawrońska K,Kwit M,Kacprzak K,Rychlewska U

更新日期：2004-08-01 00:00:00

abstract：:A method is described for the HPLC analysis of oxamniquine enantiomers in liver fraction incubates, using a second-generation alpha 1-acid glycoprotein-based column (Chiral-AGP). Oxamniquine is extracted from the incubation media by liquid-liquid extraction, using diethyl ether. The dried residue is redissolved in elu...

journal_title：Chirality

authors： Noctor TA,Fell AF,Kaye B

更新日期：1990-01-01 00:00:00

abstract：:The synthesis of the eight stereoisomers of muscarine has been efficiently accomplished by utilizing the two enantiomers of lactic esters as starting material. The synthetic strategy is based on a SnCl4-catalyzed addition of allyltrimethylsilane to O-protected lactic aldehydes followed by an iodocyclization process. A...

journal_title：Chirality

authors： De Amici M,Dallanoce C,De Micheli C,Grana E,Dondi G,Ladinsky H,Schiavi G,Zonta F

更新日期：1992-01-01 00:00:00