Abstract:
:2-Alkenyl- and 2-vinyl-5-pyrimidyl alkanols are highly enantioselective asymmetric autocatalysts with significant amplification of enantiomeric excess in the enantioselective addition of diisopropylzinc to 2-alkenyl- and 2-vinylpyrimidine-5-carbaldehydes. Consecutive asymmetric autocatalysis starting from 7% ee increases the ee of pyrimidyl alkanol up to 99% without the need for any other chiral auxillary.
journal_name
Chiralityjournal_title
Chiralityauthors
Sato I,Yanagi T,Soai Kdoi
10.1002/chir.10068subject
Has Abstractpub_date
2002-02-01 00:00:00pages
166-8issue
2-3eissn
0899-0042issn
1520-636Xpii
10.1002/chir.10068journal_volume
14pub_type
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