Enantioselective reduction of ketones with borane catalyzed by tridentate amino alcohols derived from salicylaldehyde.

Abstract:

:In the presence of tridentate chiral ligand 4e, 99% e.e. value was obtained by asymmetric reduction of ethyl benzoylacetate with borane in toluene at 25 degrees C. Various ligands and reaction conditions were investigated to develop a reasonable mechanism that explains the experimental outcomes.

journal_name

Chirality

journal_title

Chirality

authors

Lee DS

doi

10.1002/chir.20344

subject

Has Abstract

pub_date

2007-02-01 00:00:00

pages

148-51

issue

2

eissn

0899-0042

issn

1520-636X

journal_volume

19

pub_type

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