Polymorphisms in GSDMA and GSDMB are associated with asthma susceptibility, atopy and BHR.

abstract：:The purpose of this study was to determine if the interrupter technique, a noninvasive method for measuring airflow resistance, could be used to assess airway obstruction in children. In 107 children (74 with asthma, 12 with cystic fibrosis, and 21 without lung disease) conductance (mostly of airways) measured with th...

journal_title：Pediatric pulmonology

authors： Carter ER,Stecenko AA,Pollock BH,Jaeger MJ

更新日期：1994-04-01 00:00:00

abstract：BACKGROUND:In 1995 the Tucson Children's Respiratory Study (TCRS) identified clinically distinct phenotypes amongst early wheezers; the Avon Longitudinal Study of Parents And Children (ALSPAC) has recently re-examined these. OBJECTIVES:To validate statistically derived ALSPAC phenotypes in the Southampton Women's Surv...

journal_title：Pediatric pulmonology

authors： Collins SA,Pike KC,Inskip HM,Godfrey KM,Roberts G,Holloway JW,Lucas JS,Southampton Women's Survey Study Group.

更新日期：2013-07-01 00:00:00

abstract：OBJECTIVE:There is currently no evidence-based method for defining competency in pediatric flexible bronchoscopy (FB). Based on expert opinion, guidelines using numbers of procedures have been published in defining competency for pediatric FB. The purpose of this study was to formally survey the opinion of USA pediatri...

journal_title：Pediatric pulmonology

authors： Leong AB,Green CG,Kurland G,Wood RE

更新日期：2014-06-01 00:00:00

abstract：:Pertussis carries a high risk of mortality in very young infants. The mechanism of refractory cardio-respiratory failure is complex and not clearly delineated. We aimed to examine the clinico-pathological features and suggest how they may be related to outcome, by multi-center review of clinical records and post-morte...

journal_title：Pediatric pulmonology

authors： Sawal M,Cohen M,Irazuzta JE,Kumar R,Kirton C,Brundler MA,Evans CA,Wilson JA,Raffeeq P,Azaz A,Rotta AT,Vora A,Vohra A,Abboud P,Mirkin LD,Cooper M,Dishop MK,Graf JM,Petros A,Klonin H

更新日期：2009-10-01 00:00:00

abstract：:Pediatric lung transplantation has advanced over the years, providing a potential life-prolonging therapy to patients with cystic fibrosis. Despite this, many challenges in lung transplantation remain and result in worse outcomes than other solid organ transplants. As CF lung disease progresses, children and their car...

journal_title：Pediatric pulmonology

authors： Dellon E,Goldfarb SB,Hayes D Jr,Sawicki GS,Wolfe J,Boyer D

更新日期：2017-11-01 00:00:00

abstract：:Our objective was to review the clinical features and radiographic manifestations of chest wall lesions in a pediatric chest unit. Twenty-five patients (11 males and 14 females, aged 14 months to 15 years) were suspected of having a chest wall lesion on the basis of clinical examination and chest radiograph. A retrosp...

journal_title：Pediatric pulmonology

authors： Wong KS,Hung IJ,Wang CR,Lien R

更新日期：2004-03-01 00:00:00

abstract：:Neurally adjusted ventilatory assistance (NAVA) can overcome technical difficulties with synchronizing noninvasive ventilation breaths with the patient, a modality often used in very low birthweight infants (VLBW) with apnea of prematurity (AOP). This study is a retrospective single-center investigation into whether N...

journal_title：Pediatric pulmonology

authors： Tabacaru CR,Moores RR Jr,Khoury J,Rozycki HJ

更新日期：2019-11-01 00:00:00

abstract：:Childhood interstitial lung disease (chILD) comprises a wide heterogeneous group of rare parenchymal lung disorders associated with substantial morbidity and mortality. Pulmonary hypertension is a common comorbidity in adults with interstitial lung disease (ILD) and associated with poor survival. We aimed to systemati...

journal_title：Pediatric pulmonology

authors： Bromley S,Vizcaya D

更新日期：2017-05-01 00:00:00

abstract：BACKGROUND:Prone sleeping position, use of soft mattresses and head covering by bedclothes are known risk factors for sudden infant death syndrome (SIDS). Rebreathing carbon dioxide (CO(2) ) may be a possible mechanism or a confounding factor of SIDS. OBJECTIVE:To compare the aeration properties of a new concept of in...

journal_title：Pediatric pulmonology

authors： Bar-Yishay E,Gaides M,Goren A,Szeinberg A

更新日期：2011-02-01 00:00:00

abstract：:Since July 1988, a total of 92 transbronchial biopsies (TBB) have been performed in 18 patients (aged 3-16 years). Twelve patients (67%) were heart-lung transplant (HLT) recipients undergoing surveillance for pulmonary graft rejection and infection. The remainder included immunocompromised patients at risk of opportun...

journal_title：Pediatric pulmonology

authors： Whitehead B,Scott JP,Helms P,Malone M,Macrae D,Higenbottam TW,Smyth RL,Wallwork J,Elliott M,de Leval M

更新日期：1992-04-01 00:00:00

abstract：OBJECTIVE:Cystic fibrosis (CF) patients may develop hypoxemia during sleep. Limited information is available on nocturnal oxygen saturation in CF children with less severe lung disease. The aim of this study was to investigate the degree of nocturnal oxygen desaturation and factors that correlate with nocturnal oxygena...

journal_title：Pediatric pulmonology

authors： Uyan ZS,Ozdemir N,Ersu R,Akpinar I,Keskin S,Cakir E,Karadağ B,Karakoç F,Dağli E

更新日期：2007-08-01 00:00:00

abstract：:It has been suggested that children with asthma recover more quickly from exercise-induced bronchoconstriction than adults. On the basis of clinical observation we hypothesized that recovery rate from exercise-induced asthma (EIA) in childhood also decreases with age. In 14 children (aged 7-12 years) with a history of...

journal_title：Pediatric pulmonology

authors： Hofstra WB,Sterk PJ,Neijens HJ,Kouwenberg JM,Duiverman EJ

更新日期：1995-09-01 00:00:00

abstract：:Airway inflammation of eosinophilic asthma (EA) attributes to Th2 response, leaving the role of Th17 response unknown. Signal transducer and activator of transcription 3 (STAT3) induce both suppressors of cytokine signaling 3 (SOCS3) and retinoic acid receptor-related orphan nuclear receptor γ (RORγt) to initiate Th17...

journal_title：Pediatric pulmonology

authors： Lin X,Lv J,Ge D,Bai H,Yang Y,Wu J

更新日期：2020-06-01 00:00:00

abstract：:The aim of this study was to assess if the Hering-Breuer reflex could be provoked in young children. Thirty asthmatic children with a mean age of 5.3 years and 18 healthy children with a mean age of 7.0 years were studied. The presence of the reflex was indicated by prolongation of the spontaneous expiratory time foll...

journal_title：Pediatric pulmonology

authors： Greenough A,Pool J

更新日期：1991-01-01 00:00:00

abstract：:Environmental tobacco smoke, also called passive smoking, was shown to have adverse effects on the health of children. Hydrogen peroxide (H2O2) is proposed as a sensitive marker of oxidative injury and inflammatory processes in the airways, being increased in adult active cigarette smokers. We tested whether passive s...

journal_title：Pediatric pulmonology

authors： Doniec Z,Nowak D,Tomalak W,Pisiewicz K,Kurzawa R

更新日期：2005-01-01 00:00:00

abstract：RATIONALE:Secondhand smoke (SHS) has deleterious respiratory, immune, and nutritional effects in children, but there is little data regarding the effects of SHS exposure in infants with cystic fibrosis (CF). METHODS:A retrospective chart review was undertaken from 2008 to 2012 of 75 infants with CF. Growth, lung funct...

journal_title：Pediatric pulmonology

authors： Kopp BT,Sarzynski L,Khalfoun S,Hayes D Jr,Thompson R,Nicholson L,Long F,Castile R,Groner J

更新日期：2015-01-01 00:00:00

abstract：OBJECTIVES:To develop reference equations of maximal voluntary ventilation (MVV) in children and adolescents, and to test the validity and reproducibility of MVV. STUDY DESIGN:Cross-sectional study. PATIENT-SUBJECT SELECTION:A total of 348 healthy volunteers (6-17 years)-248 for the development of reference equations...

journal_title：Pediatric pulmonology

authors： Silva JC,Carvalho IE,Dal Corso S,Lanza FC

更新日期：2020-02-01 00:00:00

abstract：:Home mattresses of 24 asthmatic children with house dust mite allergy were sprayed with either benzyl-benzoate foam or placebo in a double blind fashion, 10 days before the children left the residential house for asthmatic children Istituto Pio XII (located in the Italian Alps in an environment free of mites) and went...

journal_title：Pediatric pulmonology

authors： Sette L,Comis A,Marcucci F,Sensi L,Piacentini GL,Boner AL

更新日期：1994-10-01 00:00:00

abstract：OBJECTIVE:To determine whether non-invasive positive pressure ventilation (NIPPV) delivered via nasal prongs can alleviate the need for tracheal intubation and invasive ventilation in infants admitted to the pediatric intensive care unit (PICU) with impending respiratory failure, and to find predictive factors for succ...

journal_title：Pediatric pulmonology

authors： Cavari Y,Sofer S,Rozovski U,Lazar I

更新日期：2012-10-01 00:00:00

abstract：:Even though childhood asthma is assumed to comprise reversible airway obstruction, some children develop irreversible airway obstruction (not reversed by a bronchodilator or corticosteroids); this may be due to inflammation that has caused remodeling. Lately, it has been claimed that in the absence of treatment with i...

journal_title：Pediatric pulmonology

authors： König P

更新日期：2002-04-01 00:00:00

abstract：:IL-10 is an anti-inflammatory cytokine that may have a protective role in acute lung injury. IL-10 expression is affected by a single-nucleotide polymorphism (SNP) located at position -1082 (G to A). The A allele is associated with lower IL-10 production. Low IL-10 production has been linked to the development of BPD....

journal_title：Pediatric pulmonology

authors： Yanamandra K,Boggs P,Loggins J,Baier RJ

更新日期：2005-05-01 00:00:00

abstract：PURPOSE:To examine the independent association of asthma and obesity and of their co-existence with functional exercise capacity among urban adolescents. METHODS:One hundred eighteen Hispanic- and African-American adolescents including 33 obese asthmatics, 18 normal-weight asthmatics, 38 obese non-asthmatics, and 29 n...

journal_title：Pediatric pulmonology

authors： Rastogi D,Khan UI,Isasi CR,Coupey SM

更新日期：2012-11-01 00:00:00

abstract：:Although Mycobacterium fortuitum (MF) is a non-tuberculous mycobacterium that rarely causes disease, there are reported cases of pneumonia, lung abscess, and empyema in subjects with predisposing lung disease. We report a neonate, without predisposing disease or risk factors, who manifested pneumonia and lung abscess....

journal_title：Pediatric pulmonology

authors： Glatstein M,Scolnik D,Bensira L,Domany KA,Shah M,Vala S

更新日期：2012-10-01 00:00:00

abstract：AIM:To analyze breathing pattern and mechanical ventilatory constraints during incremental exercise in healthy and cystic fibrosis (CF) children. METHODS:Thirteen healthy children and 6 children with cystic fibrosis volunteered to perform an incremental test on a treadmill. Exercise tidal flow/volume loops were plotte...

journal_title：Pediatric pulmonology

authors： Borel B,Leclair E,Thevenet D,Beghin L,Gottrand F,Fabre C

更新日期：2014-03-01 00:00:00

abstract：:A 13-year-old boy presented with a history of respiratory infection that had progressed for 3 months. A chest X-ray showed pathological findings that suggested endothoracic fascia compromise (Skarby sign). The thorax computerized axial tomography scan revealed multiple opacities in the fascia. A biopsy was performed, ...

journal_title：Pediatric pulmonology

authors： Broglia B,Bisero E,Sclavo L,Andreozzi P

更新日期：2006-05-01 00:00:00

abstract：:Tracheoesophageal fistula (TEF) with esophageal atresia (EA) is a common congenital anomaly that is associated with significant respiratory morbidity throughout life. The objective of this document is to provide a framework for the diagnosis and management of the respiratory complications that are associated with the ...

journal_title：Pediatric pulmonology

authors： Koumbourlis AC,Belessis Y,Cataletto M,Cutrera R,DeBoer E,Kazachkov M,Laberge S,Popler J,Porcaro F,Kovesi T

更新日期：2020-10-01 00:00:00

abstract：BACKGROUND:Patient-reported outcomes (PROs) are increasingly used to evaluate the efficacy of new treatments and the progression of chronic diseases. The Cystic Fibrosis Questionnaire-Revised (CFQ-R) is a disease-specific, PRO measure of health-related quality of life (HRQOL). We evaluated associations between changes ...

journal_title：Pediatric pulmonology

authors： Sawicki GS,Rasouliyan L,McMullen AH,Wagener JS,McColley SA,Pasta DJ,Quittner AL

更新日期：2011-01-01 00:00:00

abstract：:Tracheal mucosal damage has been reported in autopsy specimens of cases with proximal esophageal atresia and distal tracheoesophageal fistula (EA-TEF) (Gross classification type C). Such changes have not been reported for isolated EA (Gross classification type A). Our hypothesis is that passage of amniotic fluid (AF) ...

journal_title：Pediatric pulmonology

authors： Ateş O,Hakgüder G,Olguner M,Ozer E,Akgür FM

更新日期：2006-11-01 00:00:00

abstract：BACKGROUND:Treatment of bronchopulmonary dysplasia (BPD) remains as yet an unmet clinical need and recently stem cells have been proposed as a therapeutic tool in animal models. We investigated the role of amniotic fluid stem cells (AFS) in an adult rat model of hyperoxia lung injury. METHODS:Fifty Sprague-Dawley rats...

journal_title：Pediatric pulmonology

authors： Grisafi D,Pozzobon M,Dedja A,Vanzo V,Tomanin R,Porzionato A,Macchi V,Salmaso R,Scarpa M,Cozzi E,Fassina A,Navaglia F,Maran C,Onisto M,Caenazzo L,De Coppi P,De Caro R,Chiandetti L,Zaramella P

更新日期：2013-11-01 00:00:00

abstract：:The optimal duration of therapy for acute exacerbations of cystic fibrosis (CF) has not been defined, and the utility of serial pulmonary function testing in predicting the duration of therapy has yet to be established. In a review of 90 pulmonary exacerbations of 39 patients with CF requiring hospitalization, we foun...

journal_title：Pediatric pulmonology

authors： Rosenberg SM,Schramm CM

更新日期：1993-10-01 00:00:00