Irreversible airway obstruction in childhood asthma? A clinician's viewpoint.

abstract：:The main purpose of this study was to evaluate four different forms of treatment in young infants admitted for acute wheezing (AW). Seventy-nine infants less than one year of age were randomly assigned to one of five groups. Group 1 received nebulized fenoterol plus ipratropium bromide, group 2 fenoterol, group 3 feno...

journal_title：Pediatric pulmonology

authors： Mallol J,Barrueto L,Girardi G,Muñoz R,Puppo H,Ulloa V,Toro O,Quevedo F

更新日期：1987-09-01 00:00:00

abstract：BACKGROUND:sTREM-1 (soluble triggering receptor expressed on myeloid cells-1) is a novel inflammatory marker that may be of clinical use in cystic fibrosis (CF). Dysregulation of the TREM pathway has been demonstrated in other inflammatory diseases and modulation in animal models has therapeutic benefit. We hypothesise...

journal_title：Pediatric pulmonology

authors： Forrester DL,Barr HL,Fogarty A,Knox A

更新日期：2017-04-01 00:00:00

abstract：:Diffuse panbronchiolitis is a progressive fatal respiratory disease of unknown cause seen predominantly in Southeast Asian adults. We report this condition in a 10-year-old child of Korean birth because of the uncommon presentation at this age and the favorable outcome associated with early diagnosis. Our objective wa...

journal_title：Pediatric pulmonology

authors： Weinberger M,Fischer A,Kao S

更新日期：2015-09-01 00:00:00

abstract：:The purpose of this study was to determine if the interrupter technique, a noninvasive method for measuring airflow resistance, could be used to assess airway obstruction in children. In 107 children (74 with asthma, 12 with cystic fibrosis, and 21 without lung disease) conductance (mostly of airways) measured with th...

journal_title：Pediatric pulmonology

authors： Carter ER,Stecenko AA,Pollock BH,Jaeger MJ

更新日期：1994-04-01 00:00:00

abstract：:We present a 9-month-old infant with persistent cough refractory to conventional asthma therapy. An extensive evaluation eventually revealed a Chiari I malformation with syringohydromyelia. His cough resolved one month after surgical decompression, suggesting that brainstem compression from the Chiari malformation dir...

journal_title：Pediatric pulmonology

authors： Amos LB,Quintero DR

更新日期：2008-10-01 00:00:00

abstract：INTRODUCTION:Foreign body (FB) aspiration is a frequent and preventable source of morbidity and mortality, especially in children under 4 years of age. Few comprehensive studies exist on presentation and outcome of apple aspirations in children. METHODS:In a retrospective analysis of bronchoscopy records of a tertiary...

journal_title：Pediatric pulmonology

authors： Zychlinsky Scharff A,Schwerk N,Baumann U,Burmester H,Carlens J,Dopfer C,Grewendorf S,Mueller C,Schütz K,Voelker M,Hansen G,Happle C,Wetzke M

更新日期：2020-07-01 00:00:00

abstract：BACKGROUND:Disease burden in cystic fibrosis (CF) impacts quality of life, distress, and treatment adherence. The promoting resilience in stress management (PRISM), is a brief patient-focused intervention to promote resilience in adolescents and young adults (AYAs), which may mitigate the negative outcomes, and is prov...

journal_title：Pediatric pulmonology

authors： Toprak D,Nay L,McNamara S,Rosenberg AR,Rosenfeld M,Yi-Frazier JP

更新日期：2020-03-01 00:00:00

abstract：INTRODUCTION:Advance care planning (ACP), though recommended, has not been studied in adolescents with cystic fibrosis (CF). This quality improvement project engaged adolescents with advanced CF disease in ACP and assessed patient and CF provider attitudes and preferences regarding ACP discussions and tools. MATERIALS...

journal_title：Pediatric pulmonology

authors： Kazmerski TM,Weiner DJ,Matisko J,Schachner D,Lerch W,May C,Maurer SH

更新日期：2016-12-01 00:00:00

abstract：:For the last thirty years, oral chloral hydrate has been used for sedation of infants for lung function testing. Recently, however, availability of chloral hydrate became severely limited in the United States after two manufacturers discontinued manufacturing in 2012. Due to these limitations and the recent and ongoin...

journal_title：Pediatric pulmonology

authors： Callahan P,Pinto SJ,Kurland G,Cain JG,Motoyama EK,Weiner DJ

更新日期：2015-02-01 00:00:00

abstract：:The objective of this study was to determine the neurodevelopmental and temperamental outcome of infants who suffered an idiopathic apparent life-threatening event (IALTE) and their mothers' perceptions of such an event, and to compare such infants with a matched group of babies hospitalized for nonthreatening events....

journal_title：Pediatric pulmonology

authors： Tirosh E,Kessel A,Jaffe M,Cohen A

更新日期：1999-07-01 00:00:00

abstract：:Twenty patients with cystic fibrosis (CF) were trained to mobilize intrabronchial secretions by a new method of positive expiratory pressure mask (PEP mask) physiotherapy (PT). Patients repeatedly expired forcefully through the PEP mask; expiratory resistance was varied by eight different internal diameter resistors a...

journal_title：Pediatric pulmonology

authors： Oberwaldner B,Evans JC,Zach MS

更新日期：1986-11-01 00:00:00

abstract：BACKGROUND:Ivacaftor is a significant innovation in the treatment of cystic fibrosis (CF) with gating mutations. A substantial percentage of patients with CF have severe lung involvement, but these patients are usually excluded from phase III clinical trials. Thus, the effectiveness of ivacaftor in this population has ...

journal_title：Pediatric pulmonology

authors： Salvatore D,Carnovale V,Iacotucci P,Braggion C,Castellani C,Cimino G,Colangelo C,Francalanci M,Leonetti G,Lucidi V,Manca A,Vitullo P,Ferrara N

更新日期：2019-09-01 00:00:00

abstract：:Until the year 2000, systematic cystic fibrosis (CF) neonatal screening was only performed in a few regions of France. The Brittany region began in 1989, but not the neighboring region of Loire-Atlantique. The present study compares the clinical evolution of both affected populations 10 years after screening was start...

journal_title：Pediatric pulmonology

authors： Siret D,Bretaudeau G,Branger B,Dabadie A,Dagorne M,David V,de Braekeleer M,Moisan-Petit V,Picherot G,Rault G,Storni V,Roussey M

更新日期：2003-05-01 00:00:00

abstract：BACKGROUND:Asthma and obstructive sleep apnea (OSA) in children share multiple epidemiological risk factors and the prevalence of snoring is higher in asthmatic children, suggesting that the latter may be at increased risk for OSA. Since both asthma and OSA are inflammatory disorders, we hypothesized that polysomnograp...

journal_title：Pediatric pulmonology

authors： Kheirandish-Gozal L,Dayyat EA,Eid NS,Morton RL,Gozal D

更新日期：2011-09-01 00:00:00

abstract：:The single occlusion technique (SOT) is a simple and noninvasive technique for measurement of passive respiratory mechanics in infants. Reference values based on measurements of a large population of healthy infants performed outside specialized research laboratories are lacking. The aim of this study was to present r...

journal_title：Pediatric pulmonology

authors： Katier N,Uiterwaal CS,de Jong BM,Verheij TJ,van der Ent CK

更新日期：2006-11-01 00:00:00

abstract：:Pediatric lung transplantation has advanced over the years, providing a potential life-prolonging therapy to patients with cystic fibrosis. Despite this, many challenges in lung transplantation remain and result in worse outcomes than other solid organ transplants. As CF lung disease progresses, children and their car...

journal_title：Pediatric pulmonology

authors： Dellon E,Goldfarb SB,Hayes D Jr,Sawicki GS,Wolfe J,Boyer D

更新日期：2017-11-01 00:00:00

abstract：BACKGROUND:Asthma is a disease with reversible bronchoconstriction; however, some patients develop fixed airflow obstruction (FAO). Previous studies have reported the incidence and risk factors of FAO in adults; however, the corresponding factors in children remain poorly understood. AIM:To evaluate the incidence and ...

journal_title：Pediatric pulmonology

authors： Sousa AW,Barros Cabral AL,Arruda Martins M,Carvalho CRF

更新日期：2020-03-01 00:00:00

abstract：BACKGROUND:Multiple breath washout (MBW) is increasingly used in the clinical assessment of patients with cystic fibrosis (CF). Guidelines for MBW quality control (QC) were developed primarily for retrospective assessment and central overreading. We assessed whether real-time QC of MBW data during the measurement impro...

journal_title：Pediatric pulmonology

authors： Frauchiger BS,Carlens J,Herger A,Moeller A,Latzin P,Ramsey KA

更新日期：2021-01-01 00:00:00

abstract：:The incidence of necrotizing pneumonia and empyema complicated by bronchopleural fistula is rising. We describe the case of a 2-year-old boy who presented with empyema thoracis and necrotizing pneumonia who developed a bronchopleural fistula. At initial thoracotomy for decortication, necrotic lung was found and resect...

journal_title：Pediatric pulmonology

authors： Peters RT,Child F,Long AM,Humphrey GM,Rakoczy G

更新日期：2013-06-01 00:00:00

abstract：:Early detection of progressive lung disease in cystic fibrosis (CF) may lead to better treatment and prognosis. Routine lung function indices may be relatively insensitive markers of peripheral airway obstruction and alveolar collapse. We hypothesized that the single-breath diffusion capacity of the lung for carbon mo...

journal_title：Pediatric pulmonology

authors： Merkus PJ,Govaere ES,Hop WH,Stam H,Tiddens HA,de Jongste JC

更新日期：2004-01-01 00:00:00

abstract：:Few data are known about the effects of sleep-related breathing disorders (SRBD) on the cardiovascular system in adolescents. Forty healthy adolescents (mean age, 13.7 +/- 1.6 years) answered a questionnaire regarding symptoms of sleep-related breathing disorders (SRBD) and underwent a cardiorespiratory polygraphy and...

journal_title：Pediatric pulmonology

authors： Sánchez-Armengol A,Rodríguez-Puras MJ,Fuentes-Pradera MA,Quintana-Gallego E,Borja-Urbano G,Cayuela A,Capote F

更新日期：2003-07-01 00:00:00

abstract：:Respiratory inductive plethysmography (RIP) is a simple technique for an objective, noninvasive assessment of thoracoabdominal asynchrony, which in turn is an indirect measure of airway obstruction. We evaluated different indices of asynchrony obtained by RIP before and after methacholine-induced airway obstruction. B...

journal_title：Pediatric pulmonology

authors： Rusconi F,Gagliardi L,Aston H,Silverman M

更新日期：1995-12-01 00:00:00

abstract：:The aim of our study was to examine the effect of labor and birth canal compression on the rate of clearance of lung fluid. We recruited 10 babies born by vaginal delivery and 10 born by elective cesarean section (ECS). Thoracic gas volume (TGV) was measured using total body plethysmography, and functional residual ca...

journal_title：Pediatric pulmonology

authors： Lee S,Hassan A,Ingram D,Milner AD

更新日期：1999-05-01 00:00:00

abstract：:To determine the natural history of lung vascular remodeling and cardiac changes in the rat model of persistent pulmonary hypertension syndrome (PPHN) of the newborn, we studied fetal rats subjected to maternal indomethacin administration initiated on day 19 of gestation and continued for 2, 3, or 4 days. Animals rece...

journal_title：Pediatric pulmonology

authors： Fabris VE,Pato MD,Belik J

更新日期：2001-05-01 00:00:00

abstract：INTRODUCTION:In moderate-severe asthma exacerbation, salbutamol by inhaler (MDI) is superior to salbutamol delivered by nebulizer (NEB); however, to our knowledge, no studies in children with exclusively severe exacerbations were performed. OBJECTIVE:To compare the efficacy of salbutamol and ipratropium bromide by MDI...

journal_title：Pediatric pulmonology

authors： Iramain R,Castro-Rodriguez JA,Jara A,Cardozo L,Bogado N,Morinigo R,De Jesús R

更新日期：2019-04-01 00:00:00

abstract：:Prenatal cigarette smoke (CS) exposure, in combination with hypoxia and/or hyperthermia can lead to gasping and attenuated recovery from hypoxia in 7 days old rat pups. We studied 95 unanesthetized spontaneously breathing 14 days old rat pups to investigate if the destabilizing effects of increased ambient temperature...

journal_title：Pediatric pulmonology

authors： Pendlebury JD,Yusuf K,Bano S,Lumb KJ,Schneider JM,Hasan SU

更新日期：2012-05-01 00:00:00

abstract：OBJECTIVE:To determine the effect of changing electrode positions on vital signs and respiratory effort parameters measured with transcutaneous electromyography of the diaphragm (dEMG) in preterm infants. METHODS:In this observational study, simultaneous dEMG measurements were performed at the standard position and at...

journal_title：Pediatric pulmonology

authors： van Leuteren RW,Bekhuis RE,de Waal CG,de Jongh FH,van Kaam AH,Hutten GJ

更新日期：2020-02-01 00:00:00

abstract：:We present two infants with congenital tracheal stenosis with complete tracheal rings. Both had associated congenital anomalies. The first case showed cardiac malformations, and the second case had agenesis of the right lung. We review the literature, in particular with reference to tracheal stenosis and pulmonary age...

journal_title：Pediatric pulmonology

authors： Voland JR,Benirschke K,Saunders B

更新日期：1986-07-01 00:00:00

abstract：:Three adults with cystic fibrosis (one after lung transplantation) presented with fever, chest pain, and acute radiographic changes. The changes included a cavitary lesion of the lung, acute dense infiltrates, and lobar collapse. After failing conventional antibiotic therapy, the patients underwent flexible bronchosco...

journal_title：Pediatric pulmonology

authors： Colin AA,Tsiligiannis T,Nosé V,Waltz DA

更新日期：2006-02-01 00:00:00

abstract：:Central ventilation disorders(1) and airway obstruction(2) with chronic hypoxemia are causally related to cor pulmonale. Pulmonary vascular resistance is often reversible, and hypoxic pulmonary hypertension often responds to treatment with supplemental oxygen. Oxygen therapy during sleep may be useful as a temporary p...

journal_title：Pediatric pulmonology

authors： Hoch B,Barth H

更新日期：2001-03-01 00:00:00