Abstract:
BACKGROUND:Many studies have reported an increased incidence of psychiatric disorder (particularly psychotic disorders) among first generation adult immigrants, along with an increasing risk for ethnic minorities living in low-minority concentration neighborhoods. These studies have depended mostly on European case-based databases. In contrast, North American studies have suggested a lower risk for psychiatric disorder in immigrants, although the effect of neighborhood immigrant concentration has not been studied extensively. METHOD:Using multi-level modeling to disaggregate individual from area-level influences, this study examines the influence of first generation immigrant status at the individual level, immigrant concentration at the neighborhood-level and their combined effect on 12-month prevalence of mood, anxiety and substance-dependence disorders and lifetime prevalence of psychotic disorder, among Canadians. RESULTS:Individual-level data came from the Canadian Community Health Survey (CCHS) 1.2, a cross-sectional study of psychiatric disorder among Canadians over the age of 15 years; the sample for analysis was n=35,708. The CCHS data were linked with neighborhood-level data from the Canadian Census 2001 for multi-level logistic regression. Immigrant status was associated with a lower prevalence of psychiatric disorder, with an added protective effect for immigrants living in neighborhoods with higher immigrant concentrations. Immigrant concentration was not associated with elevated prevalence of psychiatric disorder among non-immigrants. CONCLUSIONS:The finding of lower 12-month prevalence of psychiatric disorder in Canadian immigrants, with further lessening as the neighborhood immigrant concentration increases, reflects a model of person-environment fit, highlighting the importance of studying individual risk factors within environmental contexts.
journal_name
Psychol Medjournal_title
Psychological medicineauthors
Menezes NM,Georgiades K,Boyle MHdoi
10.1017/S0033291711000213subject
Has Abstractpub_date
2011-10-01 00:00:00pages
2221-31issue
10eissn
0033-2917issn
1469-8978pii
S0033291711000213journal_volume
41pub_type
杂志文章abstract:BACKGROUND:Despite the demonstrable influence of both genes and the family environment on children's behavioural and emotional development, the mechanisms by which these factors are transmitted from parents to their children are not known. Numerous aspects of the family have long been associated with behavioural and em...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/s0033291703008948
更新日期:2004-02-01 00:00:00
abstract:BACKGROUND:Maternal depression during pregnancy increases the risk for adverse developmental outcomes in children. However, the underpinning biological mechanisms remain unknown. We tested whether depression was associated with levels of and change in the inflammatory state during pregnancy, if early pregnancy overweig...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/S0033291719001909
更新日期:2020-08-01 00:00:00
abstract:BACKGROUND:Cannabis use is associated with an earlier age at onset of psychotic illness. The aim of the present study was to examine whether this association is confounded by gender or other substance use in a large cohort of patients with a non-affective psychotic disorder. METHOD:In 785 patients with a non-affective...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/S0033291712000062
更新日期:2012-09-01 00:00:00
abstract:BACKGROUND:With regard to current neurobiological theories, the aim of our study was to examine possible alterations of temporal and frontal lobe volume in panic disorder (PD). METHOD:Seventeen in-patients with PD and a group of healthy control subjects (HC) matched for age and gender were investigated by quantitative...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/S0033291709991930
更新日期:2010-11-01 00:00:00
abstract:BACKGROUND:The effects of antidepressants for treating depressive disorders have been overestimated because of selective publication of positive trials. Reanalyses that include unpublished trials have yielded reduced effect sizes. This in turn has led to claims that antidepressants have clinically insignificant advanta...
journal_title:Psychological medicine
pub_type: 杂志文章,meta分析
doi:10.1017/S0033291713000457
更新日期:2014-03-01 00:00:00
abstract::100 randomly selected mildly or moderately mentally retarded adults were assessed for personality disorder using the Standardized Assessment of Personality devised by Mann et al. (1981). By the terms of this instrument 56% of patients showed features of abnormal personality, and in 22% this abnormality was marked, sug...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/s0033291700000799
更新日期:1987-11-01 00:00:00
abstract:BACKGROUND:Recently released prisoners are at markedly higher risk of suicide than the general population. The aim of this study was to identify key risk factors for suicide by offenders released from prisons in England and Wales. METHOD:All suicides committed by offenders within 12 months of their release from prison...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/S0033291709991048
更新日期:2010-05-01 00:00:00
abstract:BACKGROUND:Electronic medical records (EMR) provide a unique opportunity for efficient, large-scale clinical investigation in psychiatry. However, such studies will require development of tools to define treatment outcome. METHOD:Natural language processing (NLP) was applied to classify notes from 127 504 patients wit...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/S0033291711000997
更新日期:2012-01-01 00:00:00
abstract:BACKGROUND:Despite methodological differences between studies, it has been suggested that psychopathy may be associated with a ventromedial prefrontal cortex (VMPFC) deficit and antisocial personality disorder (ASPD), as classified in the DSM-IV, with a broader range of deficits in dorsolateral prefrontal cortex (DLPFC...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/S0033291711002686
更新日期:2012-08-01 00:00:00
abstract:BACKGROUND:Neuroticism has been shown to increase the risk of depression whereas extraversion is associated with a reduction of risk. These personality traits play a central role in aetiological theories of affective disorder but their role in schizophrenia is unclear. In this study, the risk for schizophrenia associat...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/s0033291701004044
更新日期:2001-08-01 00:00:00
abstract:BACKGROUND:Counselling is frequently used in the management of common mental disorders (such as anxiety and depression) in primary care. However, there are concerns over the clinical effectiveness of counselling, both in comparison with usual general practitioner care, and with other treatments such as alternative psyc...
journal_title:Psychological medicine
pub_type: 杂志文章,meta分析,评审
doi:10.1017/s0033291702006979
更新日期:2003-02-01 00:00:00
abstract:BACKGROUND:Men sexually interested in children of a specific combination of maturity and sex tend to show some lesser interest in other categories of persons. Patterns of men's sexual interest across erotic targets' categories of maturity and sex have both clinical and basic scientific implications. METHOD:We examined...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/S0033291720001476
更新日期:2020-06-01 00:00:00
abstract:BACKGROUND:Multiple studies have found Conscientiousness to be protective against dementia. The purpose of this study is to identify which specific aspects, or facets, of Conscientiousness are most protective against cognitive impairment and whether these associations are moderated by demographic factors and/or genetic...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/S0033291717002306
更新日期:2018-04-01 00:00:00
abstract:BACKGROUND:Previous research suggests that genetic influences on disordered eating may be greater in pubertal than pre-pubertal girls. Although these findings are consistent with pubertal activation of genetic influences on disordered eating, earlier studies were unable to directly test this hypothesis. The purpose of ...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/S0033291707000189
更新日期:2007-05-01 00:00:00
abstract::Sixty surviving patients from a community-based stroke register who had CT scan evidence of a single brain lesion and neurological signs appropriate to it were interviewed three to five years following their first-ever stroke. Mood disorder (anxiety and depression), physical disability, and intellectual impairment wer...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/s0033291700036503
更新日期:1990-11-01 00:00:00
abstract::There have been numerous exhortations for more 'translational research'. A selective review of historical examples of research leading to health benefits is used to consider the various forms of successful interplay between basic science and clinical applications. This is followed by a consideration of key neuroscienc...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/S003329170800398X
更新日期:2009-04-01 00:00:00
abstract:BACKGROUND:Attention-deficit/hyperactivity disorder (ADHD) is a neurodevelopmental disorder which frequently persists into adulthood. The primary goal of the current study was to (a) investigate attentional functions of stimulant medication-naïve adults with ADHD, and (b) investigate the effects of 6 weeks of methylphe...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/S0033291718003628
更新日期:2019-11-01 00:00:00
abstract:INTRODUCTION:Patients with unipolar depression show impaired performance on the Tower of London planning task. Positron emission tomography, which has previously identified resting state blood flow abnormalities in depression, was used to investigate neural activity associated with performance of this task in depressed...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/s0033291797005187
更新日期:1997-07-01 00:00:00
abstract:BACKGROUND:Little is known about the mental health of partners of survivors of high levels of trauma in post-conflict countries. METHOD:We studied 677 spouse dyads (n = 1354) drawn from a community survey (response 82.4%) in post-conflict Timor-Leste. We used culturally adapted measures of post-traumatic stress disord...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/S0033291716002233
更新日期:2017-01-01 00:00:00
abstract:BACKGROUND:The increased occurrence of obstetric complications (OCs) in patients with schizophrenia suggests that alterations in neurodevelopment may be of importance to the aetiology of the illness. Abnormal cortical folding may reflect subtle deviation from normal neurodevelopment during the foetal or neonatal period...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/S0033291711002315
更新日期:2012-06-01 00:00:00
abstract:BACKGROUND:Prior studies have suggested that major depressive disorder (MDD) with pre-adult onset represents a distinct subtype with greater symptom severity and higher rates of suicidal ideation. Whether these patients have poorer response to various types of antidepressant treatment than those with adult-onset MDD is...
journal_title:Psychological medicine
pub_type: 杂志文章,随机对照试验
doi:10.1017/S0033291712001742
更新日期:2013-05-01 00:00:00
abstract::This study examined the relationship between personality factors and depression in subjects who may have a familial vulnerability to depression (i.e. first-degree relatives of depressed patients). Four groups comprised our study sample: relatives who had never experienced a psychiatric episode of depression; relatives...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/s0033291700013052
更新日期:1987-02-01 00:00:00
abstract::A meta-analysis was carried out on 53 cases of dementia praecox (DP) and 134 cases of manic-depressive insanity (MDI) originally diagnosed by Kraepelin or his collaborators in Munich in 1908. The original case material was coded in terms of Present State Examination syndromes and analysed statistically for internal co...
journal_title:Psychological medicine
pub_type: 传,历史文章,杂志文章,meta分析
doi:10.1017/s0033291700026337
更新日期:1993-11-01 00:00:00
abstract:BACKGROUND:The past two decades have seen exponential clinical and research interest in help-seeking individuals presenting with potentially prodromal symptoms for psychosis. However, the epidemiological validity of this paradigm has been neglected, limiting future advancements in the field. METHOD:We undertook a crit...
journal_title:Psychological medicine
pub_type: 杂志文章,评审
doi:10.1017/S0033291713000184
更新日期:2014-01-01 00:00:00
abstract:BACKGROUND:Both low intelligence and low emotional control have previously been linked to a higher risk of suicide, but it is unknown whether the associations apply consistently over the life course. METHODS:The study was based on data on intelligence and emotional control, collected from 48 738 Swedish men conscripte...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/S0033291719002423
更新日期:2020-10-01 00:00:00
abstract::A sample of over 6000 women was recruited in the last trimester of pregnancy and administered a 40-item self-report questionnaire designed to detect the presence of factors that were likely to increase the risk of postpartum depression. The mental state of almost 5000 of these women was determined at around 6 to 8 wee...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/s0033291700035698
更新日期:1996-05-01 00:00:00
abstract:BACKGROUND:Recent anthropological studies have documented the importance of understanding the relation of culture to the experience of mental illness. The use of interviews that elicit explanatory models has facilitated such research, but currently available interviews are lengthy and impractical for epidemiological st...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/s0033291798007065
更新日期:1998-09-01 00:00:00
abstract::A monotonous voice is produced by schizophrenic patients whose expression of emotion is damped down and by patients with a severe degree of depression. Clinically, the distinction between these two diagnostic entities is virtually impossible to establish auditorily on the basis of voice quality alone. The laryngograph...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/s0033291700041349
更新日期:1981-11-01 00:00:00
abstract:BACKGROUND:A growing body of neuropsychological and neurobiological research shows a relationship between functioning of the prefrontal cortex and criminal and violent behaviour. The prefrontal cortex is crucial for executive functions such as inhibition, attention, working memory, set-shifting and planning. A deficit ...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/S0033291717000241
更新日期:2017-07-01 00:00:00
abstract:BACKGROUND:Quetiapine (ICI 204,636, 'Seroquel') is a new atypical antipsychotic agent with a similar binding profile to the original atypical antipsychotic, clozapine. Its clinical efficacy has already been demonstrated at multiple fixed doses (150-750 mg/day) and has been suggested to be comparable with haloperidol (1...
journal_title:Psychological medicine
pub_type: 临床试验,杂志文章,多中心研究,随机对照试验
doi:10.1017/s0033291799001476
更新日期:2000-01-01 00:00:00