Abstract：
:The spontaneous motor activity of male Wistar rats was recorded after the local application of 5-HT (10 or 40 micrograms) or 8-OH-DPAT (1 or 5 micrograms) into the dorsal raphe (DR) or median raphe (MR) nuclei. Motor activity was monitored for 30 min, beginning 10 min after injections. The injection volume was 0.5 microliters and injections were made by means of 31-ga needles at a rate of 0.33 microliters min-1. The raphe nuclei were approached at 30 degrees in order to avoid penetration of the cerebral aqueduct and also to avoid passage of the DR with injections aimed at the MR. The application of 5-HT into the DR produced a marked suppression of locomotor activity and rearing, and no or a slight increase in these variables were noted after MR injections. 8-OH-DPAT injections into the DR resulted in a decrease in locomotor activity and rearing after the 5- but not the 1-microgram dose, whereas a marked locomotor stimulation was found after injections into the MR. In the latter case 1 microgram of 8-OH-DPAT was more effective than 5 micrograms, possibly due to overstimulation by the higher dose. The results demonstrate different roles for serotonergic mechanisms in the DR and MR in the mediation of spontaneous motor activity in the rat, and also a possible specific role for 5-HT1 receptors. The involvement of 5-HT1 receptors was further supported by the ability of (-)pindolol, 2 mg kg-1 SC, to antagonise 8-OH-DPAT-induced hyperactivity after application into the MR.
journal_name
Physiol Behavjournal_title
Physiology & behaviorauthors
Hillegaart Vdoi
10.1016/0031-9384(90)90275-9subject
Has Abstractpub_date
1990-07-01 00:00:00pages
143-8issue
1eissn
0031-9384issn
1873-507Xpii
0031-9384(90)90275-9journal_volume
48pub_type
杂志文章abstract：:The question addressed was whether removal of the vomeronasal organ (VNO) of the male rat would produce observable deficits in sexual behavior. Both sexually naive and sexually experienced males were used and each animal was given more than 12 hours to mate with a receptive female. Although sexual arousal was depresse...
journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/0031-9384(86)90215-5
更新日期：1986-01-01 00:00:00
abstract：:To investigate the role of gastric contractility in the prepyloric control of meal size, we administered atropine methyl nitrate (3 mg/kg,ip) or saline prior to 30-min tests on 3 separate days in which 0.8 M sucrose was ingested by rats after 1 h of food deprivation. Ingested 0.8 M sucrose accumulated in the stomach a...
journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/0031-9384(95)02132-9
更新日期：1996-02-01 00:00:00
abstract：:Chemical neurotransmitters (NT) are principal actors in all neuronal networks of animals. The central nervous system plays an important role in stress susceptibility and organizes the response to a stressful situation through the interaction of the dopaminergic and the serotonergic pathways, leading to the activation ...
journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/j.physbeh.2016.10.005
更新日期：2016-12-01 00:00:00
abstract：:The oxytocin (OT) neural system is thought to be involved in the underlying mechanisms that guide the development of social behaviors. In the present study, we examined the effects of neonatal oxytocin manipulation in mice. Within 24 hours after birth, pups in the treatment group randomly received an intraperitoneal i...
journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/j.physbeh.2014.05.010
更新日期：2014-06-22 00:00:00
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journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/j.physbeh.2016.02.027
更新日期：2016-05-01 00:00:00
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journal_title：Physiology & behavior
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更新日期：2015-12-01 00:00:00
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journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/j.physbeh.2016.03.010
更新日期：2016-05-15 00:00:00
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journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/0031-9384(83)90277-9
更新日期：1983-12-01 00:00:00
abstract：:The effects of chronic estrogen withdrawal and subsequent hormone replacement on the feeding and body weight of adult lean and genetically obese Zucker rats were investigated. Following confirmation of a delay in the vaginal canalization of the fatty rat, subgroups of each genotype received either ovariectomy or sham ...
journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/0031-9384(79)90130-6
更新日期：1979-07-01 00:00:00
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journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/0031-9384(91)90438-t
更新日期：1991-11-01 00:00:00
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journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/0031-9384(93)90285-n
更新日期：1993-05-01 00:00:00
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journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/0031-9384(89)90346-6
更新日期：1989-10-01 00:00:00
abstract：:Suppression of sham feeding by exogenous CCK-8 or intraintestinal oleate infusion is attenuated by peripheral administration of the CCK-A receptor antagonist, devazepide, but not by the CCK-B antagonist, L365260. Likewise, systemically administered devazepide increases food intake by real feeding rats. These results s...
journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/s0031-9384(97)00519-2
更新日期：1998-02-15 00:00:00
abstract：:High intensity interval exercise (HIIE) is identified as an alternative to moderate intensity continuous exercise (MICE) due to its similar effects on outcomes including maximal oxygen uptake and glycemic control. Nevertheless, its widespread implementation in adults is questioned because acute HIIE elicits more avers...
journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/j.physbeh.2019.02.005
更新日期：2019-05-15 00:00:00
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journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/j.physbeh.2013.10.014
更新日期：2014-01-17 00:00:00
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journal_title：Physiology & behavior
pub_type： 杂志文章,随机对照试验
doi：10.1016/j.physbeh.2009.04.018
更新日期：2009-08-04 00:00:00
abstract：:Applying high temperature cooling concepts, i.e. high temperature cooling (T(supply) is 16-20°C) HVAC systems, in the built environment allows the reduction in the use of (high quality) energy. However, application of high temperature cooling systems can result in whole body and local discomfort of the occupants. Non-...
journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/j.physbeh.2012.07.008
更新日期：2012-09-10 00:00:00
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journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/0031-9384(82)90075-0
更新日期：1982-02-01 00:00:00
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journal_title：Physiology & behavior
pub_type： 杂志文章,评审
doi：10.1016/j.physbeh.2016.11.021
更新日期：2017-09-01 00:00:00
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journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/0031-9384(92)90292-a
更新日期：1992-08-01 00:00:00
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journal_title：Physiology & behavior
pub_type： 杂志文章
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更新日期：2018-10-01 00:00:00
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journal_title：Physiology & behavior
pub_type： 杂志文章
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更新日期：1997-02-01 00:00:00
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journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/0031-9384(89)90033-4
更新日期：1989-09-01 00:00:00
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journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/s0031-9384(96)00250-8
更新日期：1996-11-01 00:00:00
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journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/j.physbeh.2018.11.016
更新日期：2019-02-01 00:00:00
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journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/j.physbeh.2015.02.019
更新日期：2015-04-01 00:00:00
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journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/j.physbeh.2005.04.008
更新日期：2005-06-02 00:00:00
abstract：:Locomotor activities in the goldfish Carassius auratus were recorded under light-dark (LD) and constant light regimens. Under LD 12:12, all goldfish adjusted to given LD cycles. Activity patterns were classified into three types: L-type activity during the photophase (83%), LD-type activity both during the photophase ...
journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/0031-9384(96)00131-x
更新日期：1996-09-01 00:00:00
abstract：:We have previously established the rewarding value of clitoral stimulation (CLS) through the demonstration that manual, distributed, CLS induces a significant conditioned place preference (CPP) and conditioned partner preference in naïve, hormonally primed and non-hormonally primed rats. The present experiment asks wh...
journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/j.physbeh.2013.06.005
更新日期：2013-07-02 00:00:00
abstract：:General arousal has been operationally defined as an enhanced motor activity and enhanced intensity of response to sensory stimuli. Even though the effects of gonadal hormones on mating behavior have been much studied, their potential effect on generalized arousal, as defined above, has never been evaluated. In the pr...
journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/j.physbeh.2015.04.053
更新日期：2015-08-01 00:00:00
