Abstract:
:The effects of chronic estrogen withdrawal and subsequent hormone replacement on the feeding and body weight of adult lean and genetically obese Zucker rats were investigated. Following confirmation of a delay in the vaginal canalization of the fatty rat, subgroups of each genotype received either ovariectomy or sham surgery (Experiment 1). One hundred days later all subjects were injected subcutaneously (SC) with 1.0 microgram of estradiol benzoate (EB) daily for 16 treatment days (Experiment 2A). A second series of daily 2.0 microgram EB injections was administered intraperitoneally (IP) for 1 week (Experiment 2B). The first experiment revealed that ovariectomy produced overeating and similar weight gains in both genotypes. In the second experiment, SC hormone treatment completely reversed ovarian obesity in lean animals but failed to alter the food intake or weight gain of fatty rats. IP administration of EB depressed the feeding of fatty and lean animals to a comparable degree but a reduction in weight gain was observed only in the lean rats. These findings are discussed in light of current theories of estrogenic modulation of energy balance.
journal_name
Physiol Behavjournal_title
Physiology & behaviorauthors
Gale SK,Van Itallie TBdoi
10.1016/0031-9384(79)90130-6subject
Has Abstractpub_date
1979-07-01 00:00:00pages
111-20issue
1eissn
0031-9384issn
1873-507Xpii
0031-9384(79)90130-6journal_volume
23pub_type
杂志文章abstract::Neuroticism and depressive symptomatology have been related to a heightened and diminished physiological stress response, which may partly explain their negative relationship with health and wellbeing. Identifying factors that may increase disease vulnerability is especially relevant in older people, whose physiologic...
journal_title:Physiology & behavior
pub_type: 杂志文章
doi:10.1016/j.physbeh.2016.01.015
更新日期:2016-03-15 00:00:00
abstract::We examined the effects of 30 min of cycling exercise at a moderate intensity of 50% peak oxygen uptake, compared to 30 min of rest, on changes in emotional responses to pictorial foreground stimuli that reliably elicit unpleasant, neutral, and pleasant affect. Emotional responses were measured by self-reports of vale...
journal_title:Physiology & behavior
pub_type: 杂志文章
doi:10.1016/j.physbeh.2006.10.001
更新日期:2007-02-28 00:00:00
abstract:OBJECTIVES:To examine the mechanism of 5-lipoxygenase (5-LO) in the learning and memory dysfunction in rats subjected to chronic unpredictable mild stress (CUMS). METHODS:Eighty rats were divided into eight groups: the 0.5% sodium carboxymethyl cellulose solution (NaCMC)-treated group, empty vector (LV-Mock)-treated g...
journal_title:Physiology & behavior
pub_type: 杂志文章
doi:10.1016/j.physbeh.2016.09.010
更新日期:2016-12-01 00:00:00
abstract::Prenatal stress (PS) induces cognitive deficits, abnormal behavior patterns and physical impairments in offspring, which disturbs the developmental process. GABA systems play a key role in the brain development. The developmental trajectories are less understood although PS increases the expression of GABAAR in young ...
journal_title:Physiology & behavior
pub_type: 杂志文章
doi:10.1016/j.physbeh.2020.113184
更新日期:2021-01-01 00:00:00
abstract::We examined the hypothesis that prenatal stress potentiates defensive responsiveness which may interfere with the expression of appetitive behavioral activities. Sibling pairs of prenatally stressed and control juvenile rats were placed in an unfamiliar environment. The latency and frequency of social play, a sought-a...
journal_title:Physiology & behavior
pub_type: 杂志文章
doi:10.1016/0031-9384(92)90147-t
更新日期:1992-02-01 00:00:00
abstract::Previous studies are mainly focused on non-wooden environments, whereas few are concerned with wooden ones. How wooden indoor environments impact the physiology of the occupants is still unclear. The purpose of this study was to explore the distinct physiological responses to wooden and non-wooden indoor environments,...
journal_title:Physiology & behavior
pub_type: 杂志文章
doi:10.1016/j.physbeh.2017.02.043
更新日期:2017-05-15 00:00:00
abstract::Leucaena feed has been reported to cause disruptive effects on livestock reproduction, such as low calving percentages in cows, abortion in female goats and pigs, dead fetuses and fetal resorption in pregnant rats. In this study, the effects of Leucaena on different female reproductive variables were analyzed in two d...
journal_title:Physiology & behavior
pub_type: 杂志文章
doi:10.1016/j.physbeh.2019.112683
更新日期:2019-11-01 00:00:00
abstract::The effects of nonpharmacologically-induced deprivation of paradoxical sleep for a 24 hour period were studied in rabbits. Response characteristics commonly associated with the deprivation procedure in other species were observed, as well as features apparently peculiar to the rabbit. Like other mammals, rabbits: (1) ...
journal_title:Physiology & behavior
pub_type: 杂志文章
doi:10.1016/0031-9384(86)90352-5
更新日期:1986-01-01 00:00:00
abstract::The effects of vomeronasal organ removal (VNX) on male mouse urine marking and aggressive behaviors were investigated. In three different stimulus conditions VNX male marking rates were about half that of sham-operated males. Aggressive behavior was tested by pairing males with male-urine-swabbed castrate males. Only ...
journal_title:Physiology & behavior
pub_type: 杂志文章
doi:10.1016/0031-9384(86)90300-8
更新日期:1986-01-01 00:00:00
abstract::Many lateral hypothalamic electrodes that support self-stimulation also elicit feeding. Refractory period and conduction velocity estimates for the axons supporting these behaviors appear identical, suggesting that these behaviors may be elicited by stimulation of a common directly activated substrate. However, it is ...
journal_title:Physiology & behavior
pub_type: 杂志文章
doi:10.1016/0031-9384(90)90007-q
更新日期:1990-05-01 00:00:00
abstract::Daily fluid intakes were measured using two-bottle tests in female mice of inbred strains with high (BPH/2), normal (BPN/3) or low (BPL/1) blood pressure. The mice were offered a choice between water and different concentrations of NaCl (37.5-600 mM), KCl (1-400 mM), CaCl2 (1-100 mM) and quinine hydrochloride (0.003-1...
journal_title:Physiology & behavior
pub_type: 杂志文章
doi:10.1016/s0031-9384(98)00069-9
更新日期:1998-06-01 00:00:00
abstract::We examined the time course and sex differences of the glucocorticoid response to forced, moderate-intensity treadmill exercise in outbred laboratory house mice. Mice (n = 64 total) were divided into eight groups, each of four males and four females, which were run on a motorized treadmill at 1.0 km/h for either 0, 2,...
journal_title:Physiology & behavior
pub_type: 杂志文章
doi:10.1016/s0031-9384(97)00441-1
更新日期:1998-01-01 00:00:00
abstract::Sedentary, adult rats of both sexes fed Purina chow and a 32% sucrose solution overate, gained excess weight and had higher Lee Indexes of obesity than control animals fed only Purina chow. The magnitude of these effects was similar in the males and females. Animals of both sexes fed the sucrose diet showed a slower r...
journal_title:Physiology & behavior
pub_type: 杂志文章
doi:10.1016/0031-9384(82)90012-9
更新日期:1982-08-01 00:00:00
abstract::The research literature suggests that oxidative stress and pro-inflammatory factors influence neurotrophins in vitro. However, there is insufficient information about their effects on exercise training conditions, especially during high intensity trainings. This study aimed to compare the effects of 6weeks of high int...
journal_title:Physiology & behavior
pub_type: 杂志文章
doi:10.1016/j.physbeh.2015.04.012
更新日期:2015-08-01 00:00:00
abstract::One group of male rats was reared continuously in small, stable colonies of three animals each during a ten-week period beginning when they were 46 days old. A second group of animals was also reared in small groups of three animals each but membership within these colonies was randomly changed at weekly intervals. Th...
journal_title:Physiology & behavior
pub_type: 杂志文章
doi:10.1016/0031-9384(84)90373-1
更新日期:1984-10-01 00:00:00
abstract::Caffeine is considered a cognitive enhancer at low to moderate doses because it improves alertness, vigilance, attention, and reaction time. However, no previous investigation has assessed the effect of acute caffeine intake on e-sports-specific performance. The aim of this investigation was to determine the effect of...
journal_title:Physiology & behavior
pub_type: 杂志文章
doi:10.1016/j.physbeh.2020.113031
更新日期:2020-10-01 00:00:00
abstract::Previous research in our laboratory has demonstrated that the C57BL/6J (B/6J) mouse has a predisposition to develop severe obesity if placed on a high-fat diet. In the present study we assessed the role of physical activity in this phenomenon. Obesity-prone B/6J and obesity-resistant A/J mice were placed on one of fou...
journal_title:Physiology & behavior
pub_type: 杂志文章
doi:10.1016/0031-9384(95)02210-4
更新日期:1996-07-01 00:00:00
abstract::Early Pb exposure is known to disrupt the development of the hippocampus and result in deficits in learning and memory capacities and altered seizure susceptibility. The excitatory amino acid, NMDA, is found in high concentrations in the hippocampus and has been implicated in learning and memory functions and seizure ...
journal_title:Physiology & behavior
pub_type: 杂志文章
doi:10.1016/0031-9384(92)90398-l
更新日期:1992-10-01 00:00:00
abstract::The present experiment compared the strengths of taste aversion learning in rats induced by forced swimming in a water pool (5, 15, 30, or 60 min), voluntary running in an activity wheel (15, 30, 60, or 120 min), forced running in a motorized wheel (60 min at the speed of 8 m/min), optional running in the apparatus co...
journal_title:Physiology & behavior
pub_type: 杂志文章
doi:10.1016/j.physbeh.2006.04.013
更新日期:2006-07-30 00:00:00
abstract::Djungarian and Syrian hamsters were found to exhibit robust water intake following water deprivation, and in response to hyperosmotic and hypovolumetric challenges to body fluids following injections of hypertonic NaCl and polyethylene glycol, respectively. Water intake was not stimulated following peripheral injectio...
journal_title:Physiology & behavior
pub_type: 杂志文章
doi:10.1016/0031-9384(88)90388-5
更新日期:1988-01-01 00:00:00
abstract::Rats received total bilateral subdiaphragmatic vagotomy and, one month later, were fitted with chronic intravenous or intracerebroventricular cannulas. The vagotomized rats showed much reduced drinking compared with controls during intravenous infusion of angiotensin II. Their drinking to intracerebroventricularly adm...
journal_title:Physiology & behavior
pub_type: 杂志文章
doi:10.1016/0031-9384(80)90068-2
更新日期:1980-06-01 00:00:00
abstract::There is still controversy surrounding the effectiveness of dietary interventions for autism spectrum disorder (ASD), namely the gluten-free/casein free diet and the ketogenic diet. Additionally, as studies mainly investigated their impact on ASD symptoms and behaviors, much remains unknown about their mechanisms of a...
journal_title:Physiology & behavior
pub_type: 杂志文章,评审
doi:10.1016/j.physbeh.2018.07.014
更新日期:2018-10-01 00:00:00
abstract::The effects of stress experienced during pregnancy and raising stressed offspring on maternal behavior were investigated in Swiss-Webster mice. Dams were either stressed or not stressed during pregnancy, and raised either prenatally stressed or nonstressed cross-fostered pups. Maternal behaviors such as grooming, nurs...
journal_title:Physiology & behavior
pub_type: 杂志文章
doi:10.1016/s0031-9384(00)00431-5
更新日期:2001-03-01 00:00:00
abstract::For domestic ruminants, the male is thought to have the control over mate choice. The aim of this study was to assess the potential role the female goat plays in choosing a sexual partner. Approach frequency and proximity time to various social or sexual stimuli in a Y-maze apparatus were used as partner preference as...
journal_title:Physiology & behavior
pub_type: 杂志文章
doi:10.1016/j.physbeh.2010.01.022
更新日期:2010-04-19 00:00:00
abstract::In this study we investigated the sexually dimorphic anxiety response to a novel environment in the absence of estrogens neonatally or in adulthood. There was a sexual dimorphism in the plus-maze test after the open-field test, females being more active and less anxious. In the absence of estrogens neonatally but not ...
journal_title:Physiology & behavior
pub_type: 杂志文章
doi:10.1016/0031-9384(94)90148-1
更新日期:1994-02-01 00:00:00
abstract::In a nutrient self-selection study, CAST/EiJ mice consumed more carbohydrate than fat while C57BL/6J (B6) mice showed the opposite preference. The present study revealed similar strain differences in preferences for isocaloric fat (Intralipid) and carbohydrate (sucrose, maltodextrin) solutions in chow-fed mice. In ini...
journal_title:Physiology & behavior
pub_type: 杂志文章
doi:10.1016/j.physbeh.2018.06.018
更新日期:2018-10-01 00:00:00
abstract::Oxygen-enriched drinking water, which is increasingly sold worldwide, is claimed to "keep both the body and the mind healthy." However, currently there is no scientific evidence for such a statement. Therefore, we assessed the effect of 22 weeks of drinking oxygenated water on cognitive performance in healthy mice, us...
journal_title:Physiology & behavior
pub_type: 杂志文章
doi:10.1016/j.physbeh.2007.02.007
更新日期:2007-05-16 00:00:00
abstract::Several studies have shown that physical and/or sexual abuse during childhood may lead to the development of obesity later in life. Despite these consistent findings, the mechanism for the increased risk of obesity following developmental trauma is unknown. It has been suggested that psychological dysfunction, includi...
journal_title:Physiology & behavior
pub_type: 杂志文章
doi:10.1016/j.physbeh.2009.08.010
更新日期:2009-12-07 00:00:00
abstract::Infusions of cholecystokinin (CCK) may exert their effects on appetite by inducing feelings of nausea or anxiety. In this double blind, placebo controlled crossover study, the impact of these effects on appetite were examined. Fifteen male subjects received a 20 min i.v. infusion of cholecystokinin octapeptide (CCK-8)...
journal_title:Physiology & behavior
pub_type: 临床试验,杂志文章,多中心研究,随机对照试验
doi:10.1016/s0031-9384(98)00169-3
更新日期:1998-11-15 00:00:00
abstract::C57BL/6J male mice ordinarily kill neonatal mouse pups even if they are rendered androgen deficient by neonatal castration. Experiment 1 showed that adrenalectomy during adult life significantly decreased the tendency of neonatally gonadectomized males to kill newborns. Experiment 2 demonstrated that testosterone expo...
journal_title:Physiology & behavior
pub_type: 杂志文章
doi:10.1016/0031-9384(87)90092-8
更新日期:1987-01-01 00:00:00