Abstract:
:The allergic march is a progression of atopic disease from eczema to asthma, and then to allergic rhinoconjunctivitis. It appears to be caused by a regional allergic response with breakdown of the local epithelial barrier that initiates systemic allergic inflammation. Genetic and environmental factors predispose to developing the allergic march. There are data to support 4 possible interventions to prevent the allergic march from progressing to asthma: (1) supplements of dietary probiotics, (2) exclusive breast feeding during the first few months of life, or, alternatively (3) use of extensively hydrolyzed infant formulas, (4) treatment with inhalant allergen immunotherapy by either subcutaneous or sublingual methods.
journal_name
Otolaryngol Clin North Amjournal_title
Otolaryngologic clinics of North Americaauthors
Gordon BRdoi
10.1016/j.otc.2011.03.006subject
Has Abstractpub_date
2011-06-01 00:00:00pages
765-77, xiissue
3eissn
0030-6665issn
1557-8259pii
S0030-6665(11)00050-8journal_volume
44pub_type
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journal_title:Otolaryngologic clinics of North America
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journal_title:Otolaryngologic clinics of North America
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