The allergic march: can we prevent allergies and asthma?

Abstract:

:The allergic march is a progression of atopic disease from eczema to asthma, and then to allergic rhinoconjunctivitis. It appears to be caused by a regional allergic response with breakdown of the local epithelial barrier that initiates systemic allergic inflammation. Genetic and environmental factors predispose to developing the allergic march. There are data to support 4 possible interventions to prevent the allergic march from progressing to asthma: (1) supplements of dietary probiotics, (2) exclusive breast feeding during the first few months of life, or, alternatively (3) use of extensively hydrolyzed infant formulas, (4) treatment with inhalant allergen immunotherapy by either subcutaneous or sublingual methods.

authors

Gordon BR

doi

10.1016/j.otc.2011.03.006

subject

Has Abstract

pub_date

2011-06-01 00:00:00

pages

765-77, xi

issue

3

eissn

0030-6665

issn

1557-8259

pii

S0030-6665(11)00050-8

journal_volume

44

pub_type

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