Abstract:
:Wegener's granulomatosis is an idiopathic, granulomatous disease with the potential for multiple head and neck manifestations. The otolarygologist is an essential part of the multidisciplinary team involved in establishing the diagnosis and providing ongoing care for patients with Wegener's granulomatosis. Diagnostic difficulties abound in Wegener's granulomatosis, making repeat biopsies and the use of ANCA imperative. Medical therapy consisting of corticosteroids and immunosuppressive agents is the mainstay of treatment in Wegener's granulomatosis, whereas surgery is reserved for selected head and neck manifestations. With appropriate medical and surgical treatment, many patients living with Wegener's granulomatosis can enjoy a good quality of life.
journal_name
Otolaryngol Clin North Amjournal_title
Otolaryngologic clinics of North Americaauthors
Gubbels SP,Barkhuizen A,Hwang PHdoi
10.1016/s0030-6665(03)00023-9subject
Has Abstractpub_date
2003-08-01 00:00:00pages
685-705issue
4eissn
0030-6665issn
1557-8259pii
S0030-6665(03)00023-9journal_volume
36pub_type
杂志文章,评审abstract::This article focuses on the female patient with sleep-disordered breathing. Sleep-disordered breathing has historically been considered a disease seen primarily in men, but it has become increasingly recognized in women. Recent studies of the general population suggest that almost one third of all obstructive sleep ap...
journal_title:Otolaryngologic clinics of North America
pub_type: 杂志文章,评审
doi:10.1016/s0030-6665(02)00181-0
更新日期:2003-06-01 00:00:00
abstract::Our experience has revealed the following: (1) TRT is applicable for all types of tinnitus, as well as for decreased sound tolerance, with significant improvement of tinnitus occurring in over 80% of the cases, and at least equal success rate for decreased sound tolerance. (2) TRT can provide cure for decreased sound ...
journal_title:Otolaryngologic clinics of North America
pub_type: 杂志文章,评审
doi:10.1016/s0030-6665(02)00172-x
更新日期:2003-04-01 00:00:00
abstract::The actinic keratotic lesion appearing on the sun-exposed skin of the middle-aged and elderly is a common premalignant lesion that infrequently becomes squamous cell carcinoma. Generally, superficially destructive measures provide adequate therapy for this epidermal dysplastic growth. Because of the rare threat of squ...
journal_title:Otolaryngologic clinics of North America
pub_type: 杂志文章
doi:
更新日期:1993-02-01 00:00:00
abstract::This article is a comprehensive overview of tympanic membrane injury and its healing. Its wound healing process is unique from soft tissue because epithelialization occurs before fibrous tissue advancement. Contemporary and future modalities to improve tympanic membrane repair are also discussed in this article. ...
journal_title:Otolaryngologic clinics of North America
pub_type: 杂志文章,评审
doi:
更新日期:1995-10-01 00:00:00
abstract::An update regarding the selective application of CT scanning in acute laryngeal trauma is presented for a period encompassing 9 years. A study group of 16 patients from a larger population of 52 patients was identified as having undergone CT scanning as part of their clinical management. A rationale is presented for t...
journal_title:Otolaryngologic clinics of North America
pub_type: 杂志文章
doi:
更新日期:1991-02-01 00:00:00
abstract::The results of this study and others document the biologic behavior of acoustic neuromas. In view of the evidence presented, which describes both variable rates of individual tumor growth and spontaneous regression in size, it would seem prudent that before selecting a nonsurgical treatment modality, the growth rate f...
journal_title:Otolaryngologic clinics of North America
pub_type: 杂志文章,评审
doi:
更新日期:1992-06-01 00:00:00
abstract::Endoscopic treatment of early carcinoma of the larynx is curative, the cure rates in our experience being equal to those achieved by radiation therapy and by laryngofissure. It is highly cost effective in terms of money and of patient out-of-work time. It can be used repeatedly and does not interfere with future treat...
journal_title:Otolaryngologic clinics of North America
pub_type: 杂志文章
doi:
更新日期:1980-01-01 00:00:00
abstract::The role of cryosurgery in the treatment of tonsil disease is an unresolved issue. Initial favorable reports failed to provide the necessary incentives for larger well-controlled studies. Bacteriologic and immunologic response to the cryosurgical treatment of tonsils remains unclear. Without appropriate studies, cryos...
journal_title:Otolaryngologic clinics of North America
pub_type: 杂志文章
doi:
更新日期:1987-05-01 00:00:00
abstract::The results of tympanoplasty performed for noncholesteatomatous chronic otitis in children aged 2 to 14 years are described. The authors report that the stability of hearing was excellent; they found hearing to be equally good in young children and in older children. Tympanic membrane perforation can be closed at any ...
journal_title:Otolaryngologic clinics of North America
pub_type: 杂志文章
doi:
更新日期:1989-02-01 00:00:00
abstract::Despite being introduced in the 1970s and 1980s, CT and MRI continue to be the primary imaging modalities for the temporal bone and skull base. Although the general concepts and physics remain the same, the images obtained currently are far superior. Augmenting these traditional modalities are nuclear medicine imaging...
journal_title:Otolaryngologic clinics of North America
pub_type: 杂志文章,评审
doi:10.1016/j.otc.2007.03.001
更新日期:2007-06-01 00:00:00
abstract::Thyroid cancer will be diagnosed in more than 20,000 individuals in the United States in 2002. Approximately 16,000 of these patients will be women. During the same year, an estimated 1300 deaths from thyroid cancer are expected. The various types of thyroid cancer include papillary carcinoma, follicular carcinoma, Hu...
journal_title:Otolaryngologic clinics of North America
pub_type: 杂志文章,评审
doi:10.1016/s0030-6665(02)00127-5
更新日期:2003-02-01 00:00:00
abstract::The Sewall-Boyden flap, as used to reconstruct a frontal recess after frontoethmoidectomy, is conceptually similar to the endoscopic Lothrop procedure for surgical access to the frontal sinus. The operative technique, indications, and philosophy are presented in this article. ...
journal_title:Otolaryngologic clinics of North America
pub_type: 杂志文章,评审
doi:10.1016/s0030-6665(05)70303-0
更新日期:2001-02-01 00:00:00
abstract::Approximately 300 fungal species are known to cause mycotic disease in humans and other animals. More than 50 of these species are documented as agents of rhinosinusitis. Most such infections are caused by species of Aspergillus, Rhizopus, Alternaria, Bipolaris, and Curvularia. A growing number, however, has been attr...
journal_title:Otolaryngologic clinics of North America
pub_type: 杂志文章,评审
doi:10.1016/s0030-6665(00)80011-0
更新日期:2000-04-01 00:00:00
abstract::This article has presented suturing techniques and instrumentation and suggestions that we have found to be helpful in the management of facial soft tissue injuries. The reader is encouraged to practice suture and knot tying techniques on fresh pigfeet, which are readily accessible and inexpensive and approximate the ...
journal_title:Otolaryngologic clinics of North America
pub_type: 杂志文章
doi:
更新日期:1979-05-01 00:00:00
abstract::The technique which should be used for pediatric tracheotomy is controversial. The literature is reviewed regarding animal and human data, and our experience at Henry Ford Hospital with the flap technique is reported. Flap tracheotomy is believed to be a safe technique in children. ...
journal_title:Otolaryngologic clinics of North America
pub_type: 杂志文章
doi:
更新日期:1986-02-01 00:00:00
abstract::The optimal treatment of chordomas is maximal safe resection followed by radiation therapy. Data have shown that the use of protons has increased the local control of chordomas. Because of their physical properties, proton therapy has a sharp decline at its distal range, thereby minimizing collateral damage. However, ...
journal_title:Otolaryngologic clinics of North America
pub_type: 杂志文章,评审
doi:10.1016/j.otc.2011.08.012
更新日期:2011-10-01 00:00:00
abstract::The standard treatment for patients with advanced laryngeal cancer remains total laryngectomy. Radiotherapy as a primary treatment modality is a reasonable alternative. Surgical salvage by total laryngectomy is an important part of the treatment plan when irradiation is used primarily to treat advanced laryngeal cance...
journal_title:Otolaryngologic clinics of North America
pub_type: 杂志文章,评审
doi:
更新日期:1997-02-01 00:00:00
abstract::Acute pain management following major head and neck (HN) surgery is complex. Multimodal analgesia (MMA) regimens including acetaminophen, nonsteroidal anti-inflammatory drugs, gabapentinoids, and locoregional anesthetics are safe and effective in this population (including patients undergoing HN free flap surgery). Sp...
journal_title:Otolaryngologic clinics of North America
pub_type: 杂志文章,评审
doi:10.1016/j.otc.2020.05.005
更新日期:2020-10-01 00:00:00
abstract::The bipolar scissors, coblator, harmonic scalpel, and somnoplasty techniques are widely available and offer new choices for the operating arena. There are advantages and disadvantages to all four techniques. With time, these dissection methods will prove their lasting power. Otolaryngologists have already begun to exp...
journal_title:Otolaryngologic clinics of North America
pub_type: 杂志文章,评审
doi:10.1016/j.otc.2004.10.001
更新日期:2005-04-01 00:00:00
abstract::Obstructive sleep-disordered breathing consists of a spectrum ranging from the upper airway resistance syndrome to complete apnea. Although this disorder is relatively common, it is still under-recognized, resulting in a significant increase in morbidity and mortality. This article describes the rationale for treating...
journal_title:Otolaryngologic clinics of North America
pub_type: 杂志文章
doi:10.1016/s0030-6665(05)70133-x
更新日期:1999-04-01 00:00:00
abstract::Corticosteroids are widely used in otolaryngology to treat many disorders; however, the nature and extent of possible complications may not be completely understood. A comprehensive review of the physiology of systemic corticosteroids and literature discussing the known side effects associated with their use is presen...
journal_title:Otolaryngologic clinics of North America
pub_type: 杂志文章,评审
doi:10.1016/j.otc.2010.04.003
更新日期:2010-08-01 00:00:00
abstract::Various routes of immunotherapy (injection, intranasal, oral) using lyophilized, aqueous, glycerinated, and modified allergenic extracts have all produced blocking antibodies and symptomatic improvement. No single, empirical predetermined maintenance or optimal dose of allergenic extract right for every patient, can b...
journal_title:Otolaryngologic clinics of North America
pub_type: 杂志文章,评审
doi:
更新日期:1992-02-01 00:00:00
abstract::Mechanical endonasal dacryocystorhinostomy (DCR) involves the creation of a large rhinostomy and the preservation of lacrimal and nasal mucosa. It replicates the main advantages of the external approach to DCR using minimally invasive techniques. A thorough knowledge of intranasal anatomy and the close collaboration o...
journal_title:Otolaryngologic clinics of North America
pub_type: 杂志文章,评审
doi:10.1016/j.otc.2006.07.007
更新日期:2006-10-01 00:00:00
abstract::This article provides a concise review of contemporary options for evaluating voice disorders. Focus is given to patient history and patient-derived voice handicap and quality of life assessments, clinician-derived perceptual analysis of voice, and finally flexible and rigid, high-definition laryngoscopy with videostr...
journal_title:Otolaryngologic clinics of North America
pub_type: 杂志文章,评审
doi:10.1016/j.otc.2019.03.002
更新日期:2019-08-01 00:00:00
abstract::The evolution in thyroid function tests since the 1960s has improved the physician's proficiency in accurately identifying thyroid dysfunction in a patient with suspected thyroid disease. The mainstays of modern thyroid testing strategies are the serum TSH concentration and AMA (anti-TPO) titer. The TSH level serves a...
journal_title:Otolaryngologic clinics of North America
pub_type: 杂志文章,评审
doi:
更新日期:1996-08-01 00:00:00
abstract::Reflux is a significant contributor to cough in otolaryngology practice; cough is just one marker of its many negative effects on the upper aerodigestive tract. Reflux causes cough both by direct irritation/inflammation and by increasing sensitivities to other noxious agents. Detailed and diligent clinical evaluation,...
journal_title:Otolaryngologic clinics of North America
pub_type: 杂志文章
doi:10.1016/j.otc.2009.12.003
更新日期:2010-02-01 00:00:00
abstract::Recurrent respiratory papillomatosis (RRP) is a chronic, frequently debilitating, and potentially life-threatening disease. Therapy for RRP has evolved from simply inserting a tracheotomy to provide an airway and plucking out papillomata with cup forceps to provide some degree of voice to the present-day far more soph...
journal_title:Otolaryngologic clinics of North America
pub_type: 杂志文章,评审
doi:10.1016/j.otc.2008.09.007
更新日期:2009-02-01 00:00:00
abstract::It is evident from the foregoing that the evaluation of such a common complaint as nasal obstruction can be extremely complex. If a thorough history and examination are undertaken, however, only a small number of these investigations (if any) may be required. In each individual, it is always worth considering possible...
journal_title:Otolaryngologic clinics of North America
pub_type: 杂志文章,评审
doi:
更新日期:1992-08-01 00:00:00
abstract::Audiometric evaluation in conjunction with other components of the hearing conservation program serves to minimize the potential hazard of noise related hearing loss. Success of the industrial hearing conservation program rests in large measure with the implementation of competent audiometric testing procedures. Thus,...
journal_title:Otolaryngologic clinics of North America
pub_type: 杂志文章
doi:
更新日期:1979-08-01 00:00:00
abstract::Humans use cognitive shortcuts, or heuristics, to quickly assess and respond to situations and data. When applied inappropriately, heuristics have the potential to redirect analysis of available information in consistent ways, creating systematic biases resulting in decision errors. Heuristics have greater effect in h...
journal_title:Otolaryngologic clinics of North America
pub_type: 杂志文章,评审
doi:10.1016/j.otc.2018.08.016
更新日期:2019-02-01 00:00:00