Abstract：
:The evolution in thyroid function tests since the 1960s has improved the physician's proficiency in accurately identifying thyroid dysfunction in a patient with suspected thyroid disease. The mainstays of modern thyroid testing strategies are the serum TSH concentration and AMA (anti-TPO) titer. The TSH level serves as an endogenous indicator of the biologically active free T4 fraction and, as a result, is currently the best gauge of the thyroid status of an individual. In addition, the TSH level has other advantages over free T4 estimates in confirming the presence of thyroid disease. First, each individual has his or her own free T4-TSH setpoint, whereby any deviation from this genetically determined relationship changes the serum TSH level. Second, owing to the local nature of the T4 feedback at the pituitary, these alterations in serum TSH values amplify small changes in circulating free T4 values. The net result of these unique attributes of measuring TSH is the ability to detect thyroid dysfunction early in the course of thyroid disease. There are limitations to the use of a TSH determination as a single thyroid function test, however. They include the presence of hypothalamic or pituitary disease or concurrent nonthyroidal illness and the immediate treatment of either hyperthyroidism or hypothyroidism. Because the majority of thyroid diseases involves autoimmune processes of the thyroid gland, the inclusion of an AMA titer in any approach to thyroid testing enhances both the diagnostic and prognostic expertise of the physician. In conclusion, currently available thyroid function tests have enhanced the diagnostic skills of the physician, but their effectiveness relies on clinical judgment rather than guidance from protocol or random application.
journal_name
Otolaryngol Clin North Amjournal_title
Otolaryngologic clinics of North Americaauthors
LoPresti JSsubject
Has Abstractpub_date
1996-08-01 00:00:00pages
557-75issue
4eissn
0030-6665issn
1557-8259journal_volume
29pub_type
杂志文章,评审abstract：:The past 20 years have seen the cochlear implant evolve from an innovative but radical concept to the standard of care in the management of children with severe to profound hearing loss. All children receiving the cochlear implant achieve substantial benefit; however, performance gains are optimized by a team approach...
journal_title：Otolaryngologic clinics of North America
pub_type： 杂志文章,评审
doi：10.1016/s0030-6665(02)00059-2
更新日期：2002-08-01 00:00:00
abstract：:Facial nerve paralysis in children should be considered distinct from that which occurs in adults. The author submits a slightly different classification of facial nerve paralysis in children based on traditional thinking. Specifically, acquired facial nerve paralysis is thought to be influenced by both prenatal and p...
journal_title：Otolaryngologic clinics of North America
pub_type： 杂志文章,评审
doi：
更新日期：1991-06-01 00:00:00
abstract：:Balloon catheter dilation (BCD) is a treatment paradigm for surgical management of paranasal sinus inflammatory disease. There are few robust clinical trials evaluating the efficacy of balloon technology in chronic rhinosinusitis (CRS). The available database largely comprises retrospective, uncontrolled studies with ...
journal_title：Otolaryngologic clinics of North America
pub_type： 杂志文章,评审
doi：10.1016/j.otc.2012.06.005
更新日期：2012-10-01 00:00:00
abstract：:The significant incidence of atopy associated with otitis media with effusion (OME) has suggested a role of allergy in the pathogenesis of OME. Analysis of inflammatory mediators indicates that the mucosa of the middle ear can respond to antigen in the same way as does the mucosa of the lower respiratory tract. Recent...
journal_title：Otolaryngologic clinics of North America
pub_type： 杂志文章,评审
doi：10.1016/j.otc.2007.11.004
更新日期：2008-04-01 00:00:00
abstract：:Temporal arteritis is generally a benign and self-limiting disease, which has been recognized for approximately 50 years. Although it has been uncommon, it is becoming increasingly prevalent among elderly individuals. Its major complication involves loss of vision, and approximately 50 per cent of all untreated patien...
journal_title：Otolaryngologic clinics of North America
pub_type： 杂志文章
doi：
更新日期：1982-08-01 00:00:00
abstract：:Patients with dizziness and psychopathology present diagnostic and therapeutic challenges to clinicians in several specialties. Clinical research is beginning to define the medical-psychiatric interactions that produce many of these patients' symptoms. Treatment research is still in its infancy. A model of illness pro...
journal_title：Otolaryngologic clinics of North America
pub_type： 杂志文章,评审
doi：10.1016/s0030-6665(05)70230-9
更新日期：2000-06-01 00:00:00
abstract：:Thyroid cancer represents the most common endocrine cancer, and rates have been increasing over the last 3 decades. The treatment of cervical metastases in well differentiated thyroid cancer remains in evolution. Many questions require further resolution. Unlike many other malignancies, most large studies have found t...
journal_title：Otolaryngologic clinics of North America
pub_type： 杂志文章,评审
doi：10.1016/j.otc.2008.06.002
更新日期：2008-12-01 00:00:00
abstract：:Chronic daily headache (CDH) refers to the daily or almost daily occurrence of headache for a prolonged period of time, with lack of a well-defined attack pattern. It constitutes the vast majority of daily headaches. Hemicrania continua, a condition that closely resembles CDH, will be discussed as part of this article...
journal_title：Otolaryngologic clinics of North America
pub_type： 杂志文章,评审
doi：10.1016/s0030-6665(03)00133-6
更新日期：2003-12-01 00:00:00
abstract：:A variety of procedures are now available to manage chronic frontal sinus diseases. The choice of procedures depends upon both the extent of the disease and the experience of the surgeon. ...
journal_title：Otolaryngologic clinics of North America
pub_type： 杂志文章,评审
doi：
更新日期：1993-08-01 00:00:00
abstract：:Early identification of hearing loss and rapid rehabilitative intervention are the two key elements that will give an infant the best chance to develop normal speech and allow the family members to make appropriate adjustments that will enhance communication in the home environment. Hearing loss in an infant may be on...
journal_title：Otolaryngologic clinics of North America
pub_type： 杂志文章,评审
doi：10.1016/s0030-6665(05)70192-4
更新日期：1999-12-01 00:00:00
abstract：:Carcinoma of the paranasal sinuses is an insidious and relentless disease with a notoriously poor prognosis. Our diagnostic approach and treatment philosophy are outlined. The more recent results are also presented. ...
journal_title：Otolaryngologic clinics of North America
pub_type： 杂志文章
doi：
更新日期：1985-08-01 00:00:00
abstract：:The field of skull base surgery has expanded dramatically the surgical horizons in the treatment of skull base neoplasms, which, previously, were considered inoperable because of their locations and relation to vital structures. This article aims to offer improved understanding of surgical indications and appreciation...
journal_title：Otolaryngologic clinics of North America
pub_type： 杂志文章,评审
doi：10.1016/s0030-6665(05)70373-x
更新日期：2001-12-01 00:00:00
abstract：:Together, these tests provide a full evaluation of vestibular function in infants and small children. If attention is paid to creating the appropriate testing environment, and interpretation of the tests takes into account the unique properties of the responses of infants and young children, this testing can provide a...
journal_title：Otolaryngologic clinics of North America
pub_type： 杂志文章,评审
doi：10.1016/s0030-6665(02)00062-2
更新日期：2002-08-01 00:00:00
abstract：:Technological advancement in the operating room is evolving into a dynamic system mirroring that of the aeronautics industry. Through data visualization, information is continuously being captured, collected, and stored on a scalable informatics platform for rapid, intuitive, iterative learning. The authors believe th...
journal_title：Otolaryngologic clinics of North America
pub_type： 杂志文章,评审
doi：10.1016/j.otc.2017.01.016
更新日期：2017-06-01 00:00:00
abstract：:Allergic fungal sinusitis (AFS) is a subtype of eosinophilic chronic rhinosinusitis (CRS) characterized by type I hypersensitivity, nasal polyposis, characteristic computed tomography scan findings, eosinophilic mucus, and the presence of fungus on surgical specimens without evidence of tissue invasion. This refractor...
journal_title：Otolaryngologic clinics of North America
pub_type： 杂志文章,评审
doi：10.1016/j.otc.2012.03.003
更新日期：2012-06-01 00:00:00
abstract：:Tracheal and laryngeal stenosis has become increasingly common following prolonged intubation or tracheostomy for mechanical ventilation and is directly related to trauma. Tracheal resection up to 4 to 5 cm. with an end to end anastomosis is the generally accepted treatment. However, tracheal resection carries the dan...
journal_title：Otolaryngologic clinics of North America
pub_type： 杂志文章
doi：
更新日期：1979-11-01 00:00:00
abstract：:Chronic rhinosinusitis (CRS) is a prevalent condition that is heterogeneous in disease characteristics and multifactorial in cause. Although sinonasal mucosal inflammation in CRS is often either reversible or well-managed medically and surgically, a significant proportion of patients has a refractory form of CRS despi...
journal_title：Otolaryngologic clinics of North America
pub_type： 杂志文章,评审
doi：10.1016/j.otc.2016.08.009
更新日期：2017-02-01 00:00:00
abstract：:Chronic airway obstruction usually has an insidious onset. It is often difficult to diagnose unless the patient is examined by a physician familiar with the problem and causes. Potential causes can be divided into infectious, inflammatory, traumatic, and neoplastic. Although the precise incidence of each category is u...
journal_title：Otolaryngologic clinics of North America
pub_type： 杂志文章,评审
doi：
更新日期：1995-08-01 00:00:00
abstract：:By using the quantification method for multidimensional qualitative data, 13 variables were analyzed. The younger the patient, the stronger was the correlation between age and positive glycerin and urea tests. At ages over 50 years no correlation with positive test results was found. The longer the duration of disease...
journal_title：Otolaryngologic clinics of North America
pub_type： 杂志文章
doi：
更新日期：1983-02-01 00:00:00
abstract：:Congenital choanal atresia is a challenging clinical problem requiring prompt diagnosis and intervention. The method of repair is controversial, with no technique having gained universal acceptance. Proponents of the transnasal repair must acknowledge the variability of results, especially with thick bony plates, and ...
journal_title：Otolaryngologic clinics of North America
pub_type： 杂志文章,评审
doi：
更新日期：1997-06-01 00:00:00
abstract：:Nasal obstruction is one of the most common problems seen by pediatric otolaryngologists. Prompt treatment of nasal obstruction can be critical in newborns and infants because of their obligatory nasal breathing. Older children will typically have more inflammatory, infectious, or traumatic causes of nasal obstruction...
journal_title：Otolaryngologic clinics of North America
pub_type： 杂志文章,评审
doi：10.1016/j.otc.2018.05.005
更新日期：2018-10-01 00:00:00
abstract：:Among the several risks encountered in endoscopic sinus surgery, catastrophic orbital bleeding and iatrogenic cerebrospinal fluid leak are the two serious complications surgeons most fear. This article discusses these avoidable complications and provides treatment algorithms for intraoperative maneuvers. A thorough un...
journal_title：Otolaryngologic clinics of North America
pub_type： 杂志文章,评审
doi：10.1016/j.otc.2008.01.005
更新日期：2008-06-01 00:00:00
abstract：:The problem of food sensitivity causing chronic disorders of the ear, nose, and throat has been a known fact for many years. Diagnosis and management of the problem are well within the abilities of any concerned otolaryngologist. Precise means of laboratory diagnosis are currently being developed and should aid us in ...
journal_title：Otolaryngologic clinics of North America
pub_type： 杂志文章
doi：
更新日期：1985-11-01 00:00:00
abstract：:Otoplasty remains a challenging but rewarding operation for surgeons who approach it in a rigorous and exacting manner. This article outlines a particular systematic approach to cartilage-sparing otoplasty and related adjuvant procedures. Whichever methods are chosen, precise adherence to the goals and principles summ...
journal_title：Otolaryngologic clinics of North America
pub_type： 杂志文章
doi：10.1016/j.otc.2006.11.006
更新日期：2007-04-01 00:00:00
abstract：:The retrosigmoid technique has evolved from the traditional suboccipital operation and, when combined with removal of the posterior wall of the internal auditory canal, affords a wide exposure of the cerebellopontine angle. This approach may be used for acoustic neuromas of all sizes, from intracanalicular to more tha...
journal_title：Otolaryngologic clinics of North America
pub_type： 杂志文章,评审
doi：
更新日期：1992-04-01 00:00:00
abstract：:Corticosteroids are widely used in otolaryngology to treat many disorders; however, the nature and extent of possible complications may not be completely understood. A comprehensive review of the physiology of systemic corticosteroids and literature discussing the known side effects associated with their use is presen...
journal_title：Otolaryngologic clinics of North America
pub_type： 杂志文章,评审
doi：10.1016/j.otc.2010.04.003
更新日期：2010-08-01 00:00:00
abstract：:Burning mouth syndrome is a complex disorder of unclear etiology that is most prevalent in perimenopausal women. It is often accompanied by dysguesia and subjective xerostomia. Recent evidence implicates both central and peripheral neuropathies, possibly representing a phantom pain syndrome in some patients. Ensuring ...
journal_title：Otolaryngologic clinics of North America
pub_type： 杂志文章,评审
doi：10.1016/j.otc.2010.09.008
更新日期：2011-02-01 00:00:00
abstract：:A wide range of pathology involving the external, middle, and inner ear contribute to conductive and sensorineural hearing loss. Diagnostic imaging plays a critical role in the evaluation and management of hearing loss. High resolution computed tomography (CT) of the temporal bone and magnetic resonance imaging (MRI) ...
journal_title：Otolaryngologic clinics of North America
pub_type： 杂志文章
doi：10.1016/j.otc.2007.10.007
更新日期：2008-02-01 00:00:00
abstract：:This article discusses biophotonic and other physical methods for characterizing oral mucosa. ...
journal_title：Otolaryngologic clinics of North America
pub_type： 杂志文章,评审
doi：10.1016/j.otc.2004.10.004
更新日期：2005-04-01 00:00:00
abstract：:Endoscopy offers several distinct advantages over the operating microscope during neuro-otologic surgery that make it an excellent adjunctive tool to the microscope or independent modality during cranial base surgery. The high magnification gives excellent definition of perforating blood vessels, cranial nerves, and n...
journal_title：Otolaryngologic clinics of North America
pub_type： 杂志文章,评审
doi：10.1016/s0030-6665(02)00015-4
更新日期：2002-04-01 00:00:00
