Abstract：
:The optimal treatment of chordomas is maximal safe resection followed by radiation therapy. Data have shown that the use of protons has increased the local control of chordomas. Because of their physical properties, proton therapy has a sharp decline at its distal range, thereby minimizing collateral damage. However, this choice of radiation therapy has been limited based on the availability of resources. Given the high cost of proton facilities and improved techniques for other forms of radiation therapy, this article evaluates whether proton therapy is still superior to other radiation techniques in the treatment of chordomas.
journal_name
Otolaryngol Clin North Amjournal_title
Otolaryngologic clinics of North Americaauthors
Alonso-Basanta M,Lustig RA,Kennedy DWdoi
10.1016/j.otc.2011.08.012subject
Has Abstractpub_date
2011-10-01 00:00:00pages
1173-83issue
5eissn
0030-6665issn
1557-8259pii
S0030-6665(11)00146-0journal_volume
44pub_type
杂志文章,评审abstract：:Understanding the variety of genetic disorders affecting the inner ear demands that we first comprehend the molecular mechanisms involved in its development. Mechanisms of development can best be understood by the study of mutant organisms. Progress in the study of mammalian development has been hampered by the diffic...
journal_title：Otolaryngologic clinics of North America
pub_type： 杂志文章,评审
doi：
更新日期：1992-10-01 00:00:00
abstract：:Chronic rhinosinusitis (CRS) is a prevalent condition that is heterogeneous in disease characteristics and multifactorial in cause. Although sinonasal mucosal inflammation in CRS is often either reversible or well-managed medically and surgically, a significant proportion of patients has a refractory form of CRS despi...
journal_title：Otolaryngologic clinics of North America
pub_type： 杂志文章,评审
doi：10.1016/j.otc.2016.08.009
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abstract：:Ossicular chain reconstruction is most commonly performed for an absent or diseased incus. Reestablishing continuity by placing a strut prosthesis between the stapes capitulum and malleus handle minimizes the possibility of extrusion and displacement. Strut prostheses are made of hydroxyapetite, which is a highly bioc...
journal_title：Otolaryngologic clinics of North America
pub_type： 杂志文章,评审
doi：
更新日期：1994-08-01 00:00:00
abstract：:This article details the incidence, etiology, classification, and radiographic findings of fungal infections. Major infections discussed include aspergillosis, mucormycosis, blastomycosis, candidiasis, chromblastomycosis, coccidioidomycosis, histoplasmosis, paracoccidioidomycosis, and rhinosporidiosis. ...
journal_title：Otolaryngologic clinics of North America
pub_type： 杂志文章,评审
doi：
更新日期：1993-12-01 00:00:00
abstract：:Meniere's disease can be observed uniquely in revisions of the conservative surgical procedure for endolymphatic sac enhancement, which preserves the labyrinth, unlike destructive procedures. Genetic anatomic abnormalities in patients lead to malabsorption of endolymph and symptoms of Meniere's that are reversed by en...
journal_title：Otolaryngologic clinics of North America
pub_type： 杂志文章,评审
doi：10.1016/j.otc.2006.03.001
更新日期：2006-08-01 00:00:00
abstract：:Endoscopic septoplasty has gained popularity since Lanza and colleagues and Stammberger first described the technique. This technique has several advantages over the traditional "headlight" septoplasty. These advantages include superior visualization, accommodation of limited and minimally invasive septoplasty, and us...
journal_title：Otolaryngologic clinics of North America
pub_type： 杂志文章,评审
doi：10.1016/j.otc.2009.01.010
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abstract：:Obstructive sleep-disordered breathing consists of a spectrum ranging from the upper airway resistance syndrome to complete apnea. Although this disorder is relatively common, it is still under-recognized, resulting in a significant increase in morbidity and mortality. This article describes the rationale for treating...
journal_title：Otolaryngologic clinics of North America
pub_type： 杂志文章
doi：10.1016/s0030-6665(05)70133-x
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abstract：:Endoscopic endonasal approaches to the skull base pathology have developed and evolved dramatically over the past 2 decades, particularly with collaboration between neurosurgery and otolaryngology physicians. These advances have increased significantly the use of such approaches beyond just resection of pituitary aden...
journal_title：Otolaryngologic clinics of North America
pub_type： 杂志文章,评审
doi：10.1016/j.otc.2015.09.014
更新日期：2016-02-01 00:00:00
abstract：:Tracheal and laryngeal stenosis has become increasingly common following prolonged intubation or tracheostomy for mechanical ventilation and is directly related to trauma. Tracheal resection up to 4 to 5 cm. with an end to end anastomosis is the generally accepted treatment. However, tracheal resection carries the dan...
journal_title：Otolaryngologic clinics of North America
pub_type： 杂志文章
doi：
更新日期：1979-11-01 00:00:00
abstract：UNLABELLED:1. Do not create an emergency obstruction unless you are prepared to handle it. (It may be best to do nothing until the diagnosis is clear.) 2. Support the patient with oxygen, humidity, and positioning and monitor vital signs. 3. Take as brief, concise, and accurate a history as possible. 4. Determine the a...
journal_title：Otolaryngologic clinics of North America
pub_type： 杂志文章
doi：
更新日期：1979-05-01 00:00:00
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journal_title：Otolaryngologic clinics of North America
pub_type： 杂志文章,评审
doi：10.1016/j.otc.2013.07.001
更新日期：2013-10-01 00:00:00
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journal_title：Otolaryngologic clinics of North America
pub_type： 杂志文章,评审
doi：
更新日期：1991-08-01 00:00:00
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journal_title：Otolaryngologic clinics of North America
pub_type： 杂志文章,评审
doi：
更新日期：1987-11-01 00:00:00
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journal_title：Otolaryngologic clinics of North America
pub_type： 杂志文章
doi：
更新日期：1979-08-01 00:00:00
abstract：:Sleep-related symptoms are extremely common in patients with allergic rhinitis. Sleep impairment is likely a major contributor to the overall disease morbidity, direct and indirect health care costs, and the loss of work productivity associated with allergic rhinitis. The association between allergic rhinitis and slee...
journal_title：Otolaryngologic clinics of North America
pub_type： 杂志文章,评审
doi：10.1016/j.otc.2011.03.020
更新日期：2011-06-01 00:00:00
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journal_title：Otolaryngologic clinics of North America
pub_type： 杂志文章
doi：
更新日期：1985-11-01 00:00:00
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journal_title：Otolaryngologic clinics of North America
pub_type： 杂志文章,评审
doi：10.1016/j.otc.2012.08.004
更新日期：2012-12-01 00:00:00
abstract：:Over the years, a variety of empirical regimens have evolved using intratympanic gentamicin to treat the vertigo associated with Meniere's disease. Although these regimens have been effective, their application is not without risk. Many of the problems associated with intratympanic medications could be overcome with t...
journal_title：Otolaryngologic clinics of North America
pub_type： 杂志文章,评审
doi：
更新日期：1997-12-01 00:00:00
abstract：:Pulmonary aspiration syndromes--aspiration of gastric contents and aspiration-associated plueropulmonary infections--are discussed. ...
journal_title：Otolaryngologic clinics of North America
pub_type： 杂志文章,评审
doi：
更新日期：1988-11-01 00:00:00
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journal_title：Otolaryngologic clinics of North America
pub_type： 杂志文章,评审
doi：10.1016/j.otc.2016.12.008
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abstract：:This article focuses on the female patient with sleep-disordered breathing. Sleep-disordered breathing has historically been considered a disease seen primarily in men, but it has become increasingly recognized in women. Recent studies of the general population suggest that almost one third of all obstructive sleep ap...
journal_title：Otolaryngologic clinics of North America
pub_type： 杂志文章,评审
doi：10.1016/s0030-6665(02)00181-0
更新日期：2003-06-01 00:00:00
abstract：:Sources of trauma to the external auditory canal range from impaction of small foreign bodies to severely comminuted temporal bone fractures sustained after blunt or penetrating forces. This article provides an overview of commonly encountered injuries. The proposed systematic approach to evaluation and management is ...
journal_title：Otolaryngologic clinics of North America
pub_type： 杂志文章,评审
doi：
更新日期：1996-10-01 00:00:00
abstract：:The majority of recurrent thyroid carcinomas are histologically differentiated and readily diagnosed by light microscopy or immunohistochemical staining. Infrequently, recurrent carcinoma may be less differentiated than the index lesion, creating diagnostic challenges. Complicating issues include thyroid carcinomas th...
journal_title：Otolaryngologic clinics of North America
pub_type： 杂志文章,评审
doi：10.1016/j.otc.2008.08.001
更新日期：2008-12-01 00:00:00
abstract：:Partially implantable electromagnetic hearing aids have several potential advantages over conventional hearing aids. As conventional hearing aids improve in the quality of sound they deliver, however, the role of implant aids must be redefined. One area where they may provide the most benefit is in patients with moder...
journal_title：Otolaryngologic clinics of North America
pub_type： 杂志文章,评审
doi：
更新日期：1995-02-01 00:00:00
abstract：:The endoscope has transformed the way we observe, understand, and treat chronic ear disease. Improved view, exclusive transcanal techniques, assessment of ventilation routes and mastoid tissue preservation have led to decreased morbidity and functional enhancement of minimally invasive reconstruction of the middle ear...
journal_title：Otolaryngologic clinics of North America
pub_type： 杂志文章,评审
doi：10.1016/j.otc.2016.05.016
更新日期：2016-10-01 00:00:00
abstract：:Surgical navigation technology provides real-time intraoperative localization of surgical instruments within the field. These systems are highly accurate, assist with preoperative planning, and improve surgeon confidence. The industry has recently responded to the growing trend of treatment in ambulatory surgical cent...
journal_title：Otolaryngologic clinics of North America
pub_type： 杂志文章
doi：10.1016/j.otc.2009.07.004
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abstract：:The multidisciplinary requirements of skull base surgery have evolved over the last 25 years. The heterogeneity of tissue types in the cranium base gives rise to a diverse group of benign and malignant neoplasms with vastly different prognoses. This article reviews the distinct clinicopathologic features of some of th...
journal_title：Otolaryngologic clinics of North America
pub_type： 杂志文章,评审
doi：10.1016/s0030-6665(05)70363-7
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abstract：:This article discusses the types of telemedicine technologies that are currently in place and being used successfully in otolaryngology. It examines how these technologies have been applied in several different otolaryngology telemedicine programs and discusses their relative merits and successes. ...
journal_title：Otolaryngologic clinics of North America
pub_type： 杂志文章,评审
doi：10.1016/j.otc.2011.08.003
更新日期：2011-12-01 00:00:00
abstract：:Neuromuscular retraining is an effective method for rehabilitating facial musculature in patients with facial paralysis. This nonsurgical therapy has demonstrated improved functional outcomes and is an important adjunct to surgical treatment for restoring facial movement. Treatment begins with an intensive clinical ev...
journal_title：Otolaryngologic clinics of North America
pub_type： 杂志文章,评审
doi：
更新日期：1997-10-01 00:00:00
abstract：:Endoscopic treatment of early carcinoma of the larynx is curative, the cure rates in our experience being equal to those achieved by radiation therapy and by laryngofissure. It is highly cost effective in terms of money and of patient out-of-work time. It can be used repeatedly and does not interfere with future treat...
journal_title：Otolaryngologic clinics of North America
pub_type： 杂志文章
doi：
更新日期：1980-01-01 00:00:00
