Abstract:
:Over the years, a variety of empirical regimens have evolved using intratympanic gentamicin to treat the vertigo associated with Meniere's disease. Although these regimens have been effective, their application is not without risk. Many of the problems associated with intratympanic medications could be overcome with the use of a sustained release vehicle. This article examines the role of such vehicles in the treatment of Meniere's disease and how sustained release vehicles might impact future treatment for this disabling disease.
journal_name
Otolaryngol Clin North Amjournal_title
Otolaryngologic clinics of North Americaauthors
Hoffer ME,Balough B,Henderson J,DeCicco M,Wester D,O'Leary MJ,Kopke Rsubject
Has Abstractpub_date
1997-12-01 00:00:00pages
1159-66issue
6eissn
0030-6665issn
1557-8259journal_volume
30pub_type
杂志文章,评审abstract::Nonsquamous cell tumors of the head and neck can be reliably identified and often accurately diagnosed by proper state of the art radiologic assessment. For optimal diagnostic and preoperative work-up of head and neck lesions, complete radiologic analysis is now essential. ...
journal_title:Otolaryngologic clinics of North America
pub_type: 杂志文章
doi:
更新日期:1986-08-01 00:00:00
abstract::The management of major airway collapse in the pediatric age group has evolved and continues to evolve over time. Tracheobronchomalacia, either primary or secondary, is still the most frequent cause of major airway collapse. This article reviews tracheobronchomalacia and discusses several treatment options; from tradi...
journal_title:Otolaryngologic clinics of North America
pub_type: 杂志文章,评审
doi:10.1016/s0030-6665(05)70213-9
更新日期:2000-02-01 00:00:00
abstract::The past 20 years have seen the cochlear implant evolve from an innovative but radical concept to the standard of care in the management of children with severe to profound hearing loss. All children receiving the cochlear implant achieve substantial benefit; however, performance gains are optimized by a team approach...
journal_title:Otolaryngologic clinics of North America
pub_type: 杂志文章,评审
doi:10.1016/s0030-6665(02)00059-2
更新日期:2002-08-01 00:00:00
abstract::This article discusses the types of telemedicine technologies that are currently in place and being used successfully in otolaryngology. It examines how these technologies have been applied in several different otolaryngology telemedicine programs and discusses their relative merits and successes. ...
journal_title:Otolaryngologic clinics of North America
pub_type: 杂志文章,评审
doi:10.1016/j.otc.2011.08.003
更新日期:2011-12-01 00:00:00
abstract::The preferred antibiotic treatment for tonsillar and peritonsillar infections remains high dosages of penicillin. Peritonsillar swelling can be probed by needle aspiration. Where necessary, immediate incision and drainage of an abscess can be achieved. Quinsy tonsillectomy may be carried out for the best abscess expos...
journal_title:Otolaryngologic clinics of North America
pub_type: 杂志文章
doi:
更新日期:1987-05-01 00:00:00
abstract::Computed tomography (CT) and MRI have become an integral part of the evaluation of children with hearing loss. Abnormalities on CT or MRI are found in 20% to 50% of children with sensorineural hearing loss and correlate with the degree of hearing loss. CT and MRI have distinct advantages and disadvantages in imaging t...
journal_title:Otolaryngologic clinics of North America
pub_type: 杂志文章,评审
doi:10.1016/j.otc.2015.07.003
更新日期:2015-12-01 00:00:00
abstract::The allergic march is a progression of atopic disease from eczema to asthma, and then to allergic rhinoconjunctivitis. It appears to be caused by a regional allergic response with breakdown of the local epithelial barrier that initiates systemic allergic inflammation. Genetic and environmental factors predispose to de...
journal_title:Otolaryngologic clinics of North America
pub_type: 杂志文章,评审
doi:10.1016/j.otc.2011.03.006
更新日期:2011-06-01 00:00:00
abstract::A wide range of pathology involving the external, middle, and inner ear contribute to conductive and sensorineural hearing loss. Diagnostic imaging plays a critical role in the evaluation and management of hearing loss. High resolution computed tomography (CT) of the temporal bone and magnetic resonance imaging (MRI) ...
journal_title:Otolaryngologic clinics of North America
pub_type: 杂志文章
doi:10.1016/j.otc.2007.10.007
更新日期:2008-02-01 00:00:00
abstract::Diet hypersensitivity may be "allergic," that is, caused by some form of immunologic reaction, or nonallergic. The latter includes chemical pharmacologic, enzymatic, or dietary disorders. Food allergies may be immediate Gell and Coombs type I reactions (5%), or delayed "serum sickness" type reactions (95%). The latter...
journal_title:Otolaryngologic clinics of North America
pub_type: 杂志文章,评审
doi:
更新日期:1992-02-01 00:00:00
abstract::The results of tympanoplasty performed for noncholesteatomatous chronic otitis in children aged 2 to 14 years are described. The authors report that the stability of hearing was excellent; they found hearing to be equally good in young children and in older children. Tympanic membrane perforation can be closed at any ...
journal_title:Otolaryngologic clinics of North America
pub_type: 杂志文章
doi:
更新日期:1989-02-01 00:00:00
abstract::Despite recent, major steps forward in our understanding of tinnitus pathophysiology and improved research methodology, tinnitus remains a clear unmet clinical need. Here, the authors identify current active clinical and preclinical development programs of tinnitus drug candidates using publications, databases, and co...
journal_title:Otolaryngologic clinics of North America
pub_type: 杂志文章,评审
doi:10.1016/j.otc.2020.03.012
更新日期:2020-08-01 00:00:00
abstract::American health care is facing an epidemic of medical errors. A major cause of these errors is poor teamwork. Crisis resource management (CRM) is a set of teamwork principles derived from the airline industry. Medical simulation is an educational tool that affords health care providers a means of improving teamwork by...
journal_title:Otolaryngologic clinics of North America
pub_type: 杂志文章,评审
doi:10.1016/j.otc.2017.05.008
更新日期:2017-10-01 00:00:00
abstract::Comprehensive physical examination is essential when evaluating patients. Often it includes objective voice assessment and measures along with strobovideolaryngoscopy. In all cases physical examination involves a thorough examination of the ears, nose, throat, neck, posture, cranial nerve function (usually), and asses...
journal_title:Otolaryngologic clinics of North America
pub_type: 杂志文章,评审
doi:10.1016/j.otc.2007.05.004
更新日期:2007-10-01 00:00:00
abstract::In this article, various imaging modalities are discussed for evaluation of parotid disease, from congenital to inflammatory to neoplastic etiologies. Key imaging characteristics are outlined using case examples. Introduction to biological imaging is highlighted. Additionally, image-guided biopsy techniques are illust...
journal_title:Otolaryngologic clinics of North America
pub_type: 杂志文章,评审
doi:10.1016/j.otc.2015.10.003
更新日期:2016-04-01 00:00:00
abstract::Pediatric tracheal stenosis is a difficult problem that requires very careful preoperative evaluation and classification. Most forms of extrinsic compression are vascular in origin but can be associated with tracheomalacia, complete tracheal rings, and other anomalies of the aerodigestive tract. Optimally, both the va...
journal_title:Otolaryngologic clinics of North America
pub_type: 杂志文章,评审
doi:
更新日期:1995-08-01 00:00:00
abstract::Neoplasms of the nasopharynx are rare in children, but they threaten the child's life when they do occur. The nasopharynx tends to harbor dysontogenetic neoplasms. After classification into benign and malignant groups, nasopharyngeal neoplasms in children can be further characterized according to the age of the patien...
journal_title:Otolaryngologic clinics of North America
pub_type: 杂志文章
doi:
更新日期:1977-02-01 00:00:00
abstract::Because of the complexity and variability in the expression of otitis media, its effects on auditory function are diverse. The various influences of otitis media on auditory function are described within this article, including acoustic reflex, audiometry, and tympanometry. ...
journal_title:Otolaryngologic clinics of North America
pub_type: 杂志文章,评审
doi:
更新日期:1991-08-01 00:00:00
abstract::Among the several risks encountered in endoscopic sinus surgery, catastrophic orbital bleeding and iatrogenic cerebrospinal fluid leak are the two serious complications surgeons most fear. This article discusses these avoidable complications and provides treatment algorithms for intraoperative maneuvers. A thorough un...
journal_title:Otolaryngologic clinics of North America
pub_type: 杂志文章,评审
doi:10.1016/j.otc.2008.01.005
更新日期:2008-06-01 00:00:00
abstract::This article is a comprehensive overview of tympanic membrane injury and its healing. Its wound healing process is unique from soft tissue because epithelialization occurs before fibrous tissue advancement. Contemporary and future modalities to improve tympanic membrane repair are also discussed in this article. ...
journal_title:Otolaryngologic clinics of North America
pub_type: 杂志文章,评审
doi:
更新日期:1995-10-01 00:00:00
abstract::Reflux is a significant contributor to cough in otolaryngology practice; cough is just one marker of its many negative effects on the upper aerodigestive tract. Reflux causes cough both by direct irritation/inflammation and by increasing sensitivities to other noxious agents. Detailed and diligent clinical evaluation,...
journal_title:Otolaryngologic clinics of North America
pub_type: 杂志文章
doi:10.1016/j.otc.2009.12.003
更新日期:2010-02-01 00:00:00
abstract::An improved nomenclature framework is crucial to improve communication regarding voice problems and to advance the field of voice disorders. The subjective nature of the voice evaluation process does not lend itself readily to uniformity and most voice-disordered patients demonstrate multiple pathologic processes. In ...
journal_title:Otolaryngologic clinics of North America
pub_type: 杂志文章,评审
doi:10.1016/s0030-6665(05)70262-0
更新日期:2000-10-01 00:00:00
abstract::Neurotologic and skull base surgery involves working around important neurovascular and neurotologic structures and can incur unwarranted complications. Knowledge of surgical anatomy, good preoperative planning, intraoperative monitoring, and excellent microsurgical technique contribute to minimizing and avoiding comp...
journal_title:Otolaryngologic clinics of North America
pub_type: 杂志文章,评审
doi:10.1016/j.otc.2007.03.008
更新日期:2007-06-01 00:00:00
abstract::The significant incidence of atopy associated with otitis media with effusion (OME) has suggested a role of allergy in the pathogenesis of OME. Analysis of inflammatory mediators indicates that the mucosa of the middle ear can respond to antigen in the same way as does the mucosa of the lower respiratory tract. Recent...
journal_title:Otolaryngologic clinics of North America
pub_type: 杂志文章,评审
doi:10.1016/j.otc.2007.11.004
更新日期:2008-04-01 00:00:00
abstract::Vascular tumors are benign neoplasms, which result from proliferating endothelial cells. These lesions present during infancy or childhood, may affect any location, and exhibit postnatal growth. Local complications include bleeding, tissue destruction, and pain whereas systemic sequelae include thrombocytopenia, conge...
journal_title:Otolaryngologic clinics of North America
pub_type: 杂志文章,评审
doi:10.1016/j.otc.2017.09.008
更新日期:2018-02-01 00:00:00
abstract::The debate between the skin testing allergist and the in vitro testing allergist goes on. Clearly, the in vitro methods of allergy testing are here to stay. In vitro testing is less limiting and offers a number of advantages to both the allergist and the patient. ...
journal_title:Otolaryngologic clinics of North America
pub_type: 杂志文章
doi:
更新日期:1985-11-01 00:00:00
abstract::CT scanning of the ethmoid sinuses is a significant advancement in the diagnostic evaluation of patients with pathology in this region. It allows for simultaneous and accurate evaluation of fine bony detail as well as subtle soft tissue abnormalities. ...
journal_title:Otolaryngologic clinics of North America
pub_type: 杂志文章,评审
doi:
更新日期:1985-02-01 00:00:00
abstract::The following are our conclusions in regard to glycerol test interpretation based on 60 valve implants: Negative Tests 1. A negative glycerol test result and no audiometric evidence of significant hearing fluctuations indicate that a patient is unlikely to have postoperative hearing that is better than his best preope...
journal_title:Otolaryngologic clinics of North America
pub_type: 杂志文章
doi:
更新日期:1980-11-01 00:00:00
abstract::There are several advances in diagnosis and management for the otolaryngologist treating allergy. These include new technologies and the refinement of current techniques, and reflect overall trends in health care toward personalized medicine. Local immunoglobulin, urinary leukotriene E4, lipidomics, microRNA within ex...
journal_title:Otolaryngologic clinics of North America
pub_type: 杂志文章,评审
doi:10.1016/j.otc.2017.08.014
更新日期:2017-12-01 00:00:00
abstract::Advances in imaging and endoscopic techniques have improved the ability to diagnose, localize, and treat in a less morbid fashion CSF leaks of the anterior skull base. An appreciation for the mechanism of leak and of the relationship between CSF production and absorption must be kept in mind when individualizing a rep...
journal_title:Otolaryngologic clinics of North America
pub_type: 杂志文章,评审
doi:10.1016/j.otc.2005.03.011
更新日期:2005-08-01 00:00:00
abstract::This article presents an approach to reanimation of the midface in long-standing flaccid facial palsy by means of functional free gracilis transfer and static facial suspension. ...
journal_title:Otolaryngologic clinics of North America
pub_type: 杂志文章,评审
doi:10.1016/j.otc.2018.07.009
更新日期:2018-12-01 00:00:00