Abstract：
:Fanconi anemia (FA) is a rare disorder inherited in an autosomal recessive fashion, with an estimated incidence of 1:360,000 births. Although hematologic complications are the most common manifestation of this disease, cancers, especially of the head and neck, are also prominent. The chromosomal fragility of patients with FA necessitates careful planning of therapy and monitoring, and awareness of this rare disorder is crucial to recognizing it in the clinic.
journal_name
Otolaryngol Clin North Amjournal_title
Otolaryngologic clinics of North Americaauthors
Lin J,Kutler DIdoi
10.1016/j.otc.2013.04.002subject
Has Abstractpub_date
2013-08-01 00:00:00pages
567-77issue
4eissn
0030-6665issn
1557-8259pii
S0030-6665(13)00041-8journal_volume
46pub_type
杂志文章,评审abstract：:Allergic rhinitis (AR) is a global disease affecting hundreds of millions internationally. Substantial pharmacologic gains have been made in the treatment of allergy, including antihistamines, steroids, and leukotriene inhibitors. Pharmacology and immunotherapy are the 2 primary choices in an otolaryngologist's armame...
journal_title：Otolaryngologic clinics of North America
pub_type： 杂志文章,评审
doi：10.1016/j.otc.2012.12.005
更新日期：2013-06-01 00:00:00
abstract：:Because of the complexity and variability in the expression of otitis media, its effects on auditory function are diverse. The various influences of otitis media on auditory function are described within this article, including acoustic reflex, audiometry, and tympanometry. ...
journal_title：Otolaryngologic clinics of North America
pub_type： 杂志文章,评审
doi：
更新日期：1991-08-01 00:00:00
abstract：:Approximately 300 fungal species are known to cause mycotic disease in humans and other animals. More than 50 of these species are documented as agents of rhinosinusitis. Most such infections are caused by species of Aspergillus, Rhizopus, Alternaria, Bipolaris, and Curvularia. A growing number, however, has been attr...
journal_title：Otolaryngologic clinics of North America
pub_type： 杂志文章,评审
doi：10.1016/s0030-6665(00)80011-0
更新日期：2000-04-01 00:00:00
abstract：:The debate between the skin testing allergist and the in vitro testing allergist goes on. Clearly, the in vitro methods of allergy testing are here to stay. In vitro testing is less limiting and offers a number of advantages to both the allergist and the patient. ...
journal_title：Otolaryngologic clinics of North America
pub_type： 杂志文章
doi：
更新日期：1985-11-01 00:00:00
abstract：:This article outlines the historical development of the use of lasers in the tracheobronchial tree, the current indications for the use of carbon dioxide and neodymium:yttrium-aluminum-garnet lasers, and the management of complications. The merits of other laser wavelengths are mentioned, including use of the potassiu...
journal_title：Otolaryngologic clinics of North America
pub_type： 历史文章,杂志文章,评审
doi：
更新日期：1996-12-01 00:00:00
abstract：:This article provides an overview of nonsurgical and nonpharmacologic treatments for oropharyngeal dysphagia. The speech-language pathologist (SLP) is the primary member of the swallowing management team who will provide this type of dysphagia management. The primary focus of the SLP for dysphagia management is first ...
journal_title：Otolaryngologic clinics of North America
pub_type： 杂志文章
doi：10.1016/j.otc.2013.08.003
更新日期：2013-12-01 00:00:00
abstract：:The otolaryngologist will find in this article a direct and frank discussion and useful advice for how to get started performing solely endoscopic ear surgery for abnormalities of the middle ear. The author provides discussion and photos based on his experience with this procedure. Presented herein are selection of th...
journal_title：Otolaryngologic clinics of North America
pub_type： 杂志文章,评审
doi：10.1016/j.otc.2012.10.009
更新日期：2013-04-01 00:00:00
abstract：:Technological advancement in the operating room is evolving into a dynamic system mirroring that of the aeronautics industry. Through data visualization, information is continuously being captured, collected, and stored on a scalable informatics platform for rapid, intuitive, iterative learning. The authors believe th...
journal_title：Otolaryngologic clinics of North America
pub_type： 杂志文章,评审
doi：10.1016/j.otc.2017.01.016
更新日期：2017-06-01 00:00:00
abstract：:Assessment of the nose is critical in evaluating obstructive sleep apnea (OSA) because the nose plays an important role in the physiology of sleep by regulating nasal airway resistance and stimulating ventilation. Nasal obstruction is common in sleep apnea, contributes to OSA, and interferes with tolerance of OSA trea...
journal_title：Otolaryngologic clinics of North America
pub_type： 杂志文章,评审
doi：10.1016/j.otc.2020.02.002
更新日期：2020-06-01 00:00:00
abstract：:Bilateral vocal cord paralysis in children with its many causes presents a challenging problem to the pediatric otolaryngologist. Traditionally, management of bilateral vocal cord paralysis includes securing the airway with a tracheotomy and waiting for spontaneous recovery. Surgeons have tried a variety of surgical p...
journal_title：Otolaryngologic clinics of North America
pub_type： 杂志文章,评审
doi：10.1016/j.otc.2008.04.003
更新日期：2008-10-01 00:00:00
abstract：:The use of minimally invasive and endoscopic thyroidectomy techniques has become widespread. However, these procedures all result in a visible neck incision. Several remote access thyroidectomy approaches that place the necessary incision in inconspicuous, noncervical locations have recently been described. Robotic fa...
journal_title：Otolaryngologic clinics of North America
pub_type： 杂志文章,评审
doi：10.1016/j.otc.2014.02.001
更新日期：2014-06-01 00:00:00
abstract：:Advances in management of adult skull base pathologies are increasingly being applied in children. Pediatric patients present special challenges because of their smaller anatomy, but potential gains in reduced morbidity make improvements in skull base approaches well worth pursuing. ...
journal_title：Otolaryngologic clinics of North America
pub_type： 杂志文章,评审
doi：10.1016/j.otc.2005.03.001
更新日期：2005-08-01 00:00:00
abstract：:The nasal septum is a structure poorly understood and appreciated by the lay public and the nonotolaryngologist--head and neck surgeon alike. Deviation of the caudal portion of the nasal septum may result in nasal obstruction, a crooked nose, and columellar irregularities. The correction of a severely deviated caudal ...
journal_title：Otolaryngologic clinics of North America
pub_type： 杂志文章,评审
doi：10.1016/j.otc.2009.03.005
更新日期：2009-06-01 00:00:00
abstract：:Benign and malignant tumors, including polyps, represent conditions that occur frequently enough to be considered in the differential diagnosis of sinus disease. The locations and extent of these lesions (especially malignant tumors) should be evaluated by CT and MRI. This is especially indicated when malignant lesion...
journal_title：Otolaryngologic clinics of North America
pub_type： 杂志文章,评审
doi：
更新日期：1988-08-01 00:00:00
abstract：:Obstructive apnea, especially OSA, is a common problem in pediatric practice. In young infants, craniofacial anomalies may be the most common contributor to OSA. Complications include failure to thrive, metabolic alkalosis, and respiratory distress which can be life-threatening. In children over the age of 2 years, ad...
journal_title：Otolaryngologic clinics of North America
pub_type： 杂志文章,评审
doi：
更新日期：1990-08-01 00:00:00
abstract：:An understanding of the anatomy of the paranasal sinuses is essential for successful endoscopic sinus surgery. The anatomy of the sinuses is carefully described and illustrated. ...
journal_title：Otolaryngologic clinics of North America
pub_type： 杂志文章
doi：
更新日期：1989-08-01 00:00:00
abstract：:Chronic ear disease is a major cause of acquired hearing loss in the developing world. It is prevalent on every continent, but occurs more commonly in poorer nations owing to a lack of preventative measures. This article outlines the particular challenges in treating this disease in the developing world, including a d...
journal_title：Otolaryngologic clinics of North America
pub_type： 杂志文章,评审
doi：10.1016/j.otc.2018.01.017
更新日期：2018-06-01 00:00:00
abstract：:The majority of recurrent thyroid carcinomas are histologically differentiated and readily diagnosed by light microscopy or immunohistochemical staining. Infrequently, recurrent carcinoma may be less differentiated than the index lesion, creating diagnostic challenges. Complicating issues include thyroid carcinomas th...
journal_title：Otolaryngologic clinics of North America
pub_type： 杂志文章,评审
doi：10.1016/j.otc.2008.08.001
更新日期：2008-12-01 00:00:00
abstract：:Balloon catheter dilation (BCD) is a treatment paradigm for surgical management of paranasal sinus inflammatory disease. There are few robust clinical trials evaluating the efficacy of balloon technology in chronic rhinosinusitis (CRS). The available database largely comprises retrospective, uncontrolled studies with ...
journal_title：Otolaryngologic clinics of North America
pub_type： 杂志文章,评审
doi：10.1016/j.otc.2012.06.005
更新日期：2012-10-01 00:00:00
abstract：:The carbon dioxide laser has been used in a variety of otolaryngologic conditions. Its specific advantages have particularly lent themselves to its use in the airway. The role of laser endoscopic treatment in subglottic and tracheal stenosis will continue to expand and aid in the successful management of these difficu...
journal_title：Otolaryngologic clinics of North America
pub_type： 杂志文章,评审
doi：
更新日期：1983-11-01 00:00:00
abstract：:Despite recent, major steps forward in our understanding of tinnitus pathophysiology and improved research methodology, tinnitus remains a clear unmet clinical need. Here, the authors identify current active clinical and preclinical development programs of tinnitus drug candidates using publications, databases, and co...
journal_title：Otolaryngologic clinics of North America
pub_type： 杂志文章,评审
doi：10.1016/j.otc.2020.03.012
更新日期：2020-08-01 00:00:00
abstract：:Since the description of a transnasal approach for treatment of pituitary tumors, transsphenoidal surgery has undergone continuous development. Hirsch developed a lateral endonasal approach before simplifying it to a transseptal approach. Cushing approached pituitary tumors using a transsphenoidal approach but transit...
journal_title：Otolaryngologic clinics of North America
pub_type： 杂志文章,评审
doi：10.1016/j.otc.2015.09.005
更新日期：2016-02-01 00:00:00
abstract：:This article summarizes the current management of pediatric thyroid disease, with an emphasis on surgical management. Medical and surgical approaches to hyperthyroidism are reviewed as well as pathways for evaluation of nodules and malignancy. Differences between pediatric and adult thyroid management are highlighted....
journal_title：Otolaryngologic clinics of North America
pub_type： 杂志文章,评审
doi：10.1016/j.otc.2019.06.009
更新日期：2019-10-01 00:00:00
abstract：:Chronic rhinosinusitis (CRS) is a prevalent condition that is heterogeneous in disease characteristics and multifactorial in cause. Although sinonasal mucosal inflammation in CRS is often either reversible or well-managed medically and surgically, a significant proportion of patients has a refractory form of CRS despi...
journal_title：Otolaryngologic clinics of North America
pub_type： 杂志文章,评审
doi：10.1016/j.otc.2016.08.009
更新日期：2017-02-01 00:00:00
abstract：:Together, these tests provide a full evaluation of vestibular function in infants and small children. If attention is paid to creating the appropriate testing environment, and interpretation of the tests takes into account the unique properties of the responses of infants and young children, this testing can provide a...
journal_title：Otolaryngologic clinics of North America
pub_type： 杂志文章,评审
doi：10.1016/s0030-6665(02)00062-2
更新日期：2002-08-01 00:00:00
abstract：:This article focuses on the rare and obscure complications of endoscopic sinus surgery. The majority of surgeons will not encounter these complications in their practice, but should be aware of their possibility. With knowledge of these rare complications, the surgeon can understand the possible avoidance as well as u...
journal_title：Otolaryngologic clinics of North America
pub_type： 杂志文章,评审
doi：10.1016/j.otc.2015.05.012
更新日期：2015-10-01 00:00:00
abstract：:There have been many advances in microsurgery for voice professionals over the last three decades. Driven by a greater understanding of the anatomy and physiology of phonation, most of the advances provide greater surgical precision through improved exposure and more delicate instrumentation. Laryngologists who perfor...
journal_title：Otolaryngologic clinics of North America
pub_type： 杂志文章,评审
doi：10.1016/j.otc.2007.05.015
更新日期：2007-10-01 00:00:00
abstract：:Facial nerve dysfunction after resection of a vestibular schwannoma is one of the most common indications for facial nerve habilitation. This article presents an overview of common and emerging management options for facial habilitation following resection of a vestibular schwannoma. Immediate and delayed nerve repair...
journal_title：Otolaryngologic clinics of North America
pub_type： 杂志文章,评审
doi：10.1016/j.otc.2011.12.015
更新日期：2012-04-01 00:00:00
abstract：:Cyanoacrylate and fibrin tissue adhesives can aid the facial plastic surgeon performing surgery in the outpatient setting. Octyl-2-cyanoacrylate is ideal for superficial skin closure and eliminates the need for suture removal. Subcutaneous sutures are needed in most cases to provide the best cosmetic outcomes. Fibrin ...
journal_title：Otolaryngologic clinics of North America
pub_type： 杂志文章
doi：10.1016/s0030-6665(03)00097-5
更新日期：2002-02-01 00:00:00
abstract：:There are two undeniable attributes of radiotherapy: its value in controlling head and neck malignancies and the progressive damage it inflicts on all treated tissues. It is fortunate that over the past decade, we have developed techniques and treatments that counteract, at least in part, the negative effects of radio...
journal_title：Otolaryngologic clinics of North America
pub_type： 杂志文章,评审
doi：
更新日期：1995-10-01 00:00:00
