Abstract:
:Despite recent, major steps forward in our understanding of tinnitus pathophysiology and improved research methodology, tinnitus remains a clear unmet clinical need. Here, the authors identify current active clinical and preclinical development programs of tinnitus drug candidates using publications, databases, and company communications. The current drug development programs hold promise for new therapeutic options for tinnitus patients, but further fundamental research is needed to validate additional targets for treating tinnitus.
journal_name
Otolaryngol Clin North Amjournal_title
Otolaryngologic clinics of North Americaauthors
Dyhrfjeld-Johnsen J,Cederroth CRdoi
10.1016/j.otc.2020.03.012subject
Has Abstractpub_date
2020-08-01 00:00:00pages
651-666issue
4eissn
0030-6665issn
1557-8259pii
S0030-6665(20)30049-9journal_volume
53pub_type
杂志文章,评审abstract::The past 20 years have seen the cochlear implant evolve from an innovative but radical concept to the standard of care in the management of children with severe to profound hearing loss. All children receiving the cochlear implant achieve substantial benefit; however, performance gains are optimized by a team approach...
journal_title:Otolaryngologic clinics of North America
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abstract::Benign and malignant tumors, including polyps, represent conditions that occur frequently enough to be considered in the differential diagnosis of sinus disease. The locations and extent of these lesions (especially malignant tumors) should be evaluated by CT and MRI. This is especially indicated when malignant lesion...
journal_title:Otolaryngologic clinics of North America
pub_type: 杂志文章,评审
doi:
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journal_title:Otolaryngologic clinics of North America
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journal_title:Otolaryngologic clinics of North America
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abstract::The problem of food sensitivity causing chronic disorders of the ear, nose, and throat has been a known fact for many years. Diagnosis and management of the problem are well within the abilities of any concerned otolaryngologist. Precise means of laboratory diagnosis are currently being developed and should aid us in ...
journal_title:Otolaryngologic clinics of North America
pub_type: 杂志文章
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abstract::Simulation-based boot camps are growing in popularity and are effective in onboarding novice residents with new knowledge, skills, and behaviors. These intensive and immersive courses may be used to train residents and allied health professionals in specific procedures, teamwork, and management of rare clinical scenar...
journal_title:Otolaryngologic clinics of North America
pub_type: 杂志文章,评审
doi:10.1016/j.otc.2017.05.010
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abstract::Thyroid cancer will be diagnosed in more than 20,000 individuals in the United States in 2002. Approximately 16,000 of these patients will be women. During the same year, an estimated 1300 deaths from thyroid cancer are expected. The various types of thyroid cancer include papillary carcinoma, follicular carcinoma, Hu...
journal_title:Otolaryngologic clinics of North America
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abstract::An update regarding the selective application of CT scanning in acute laryngeal trauma is presented for a period encompassing 9 years. A study group of 16 patients from a larger population of 52 patients was identified as having undergone CT scanning as part of their clinical management. A rationale is presented for t...
journal_title:Otolaryngologic clinics of North America
pub_type: 杂志文章
doi:
更新日期:1991-02-01 00:00:00
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journal_title:Otolaryngologic clinics of North America
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journal_title:Otolaryngologic clinics of North America
pub_type: 杂志文章
doi:
更新日期:1980-05-01 00:00:00
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journal_title:Otolaryngologic clinics of North America
pub_type: 历史文章,杂志文章
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journal_title:Otolaryngologic clinics of North America
pub_type: 杂志文章,评审
doi:
更新日期:1993-12-01 00:00:00
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journal_title:Otolaryngologic clinics of North America
pub_type: 杂志文章,评审
doi:
更新日期:1997-08-01 00:00:00
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journal_title:Otolaryngologic clinics of North America
pub_type: 杂志文章,评审
doi:
更新日期:1987-08-01 00:00:00
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journal_title:Otolaryngologic clinics of North America
pub_type: 杂志文章,评审
doi:10.1016/j.otc.2015.02.007
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journal_title:Otolaryngologic clinics of North America
pub_type: 杂志文章,评审
doi:10.1016/j.otc.2005.08.005
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journal_title:Otolaryngologic clinics of North America
pub_type: 杂志文章,评审
doi:
更新日期:1995-06-01 00:00:00
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journal_title:Otolaryngologic clinics of North America
pub_type: 杂志文章,评审
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journal_title:Otolaryngologic clinics of North America
pub_type: 杂志文章,评审
doi:
更新日期:1994-02-01 00:00:00
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journal_title:Otolaryngologic clinics of North America
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journal_title:Otolaryngologic clinics of North America
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journal_title:Otolaryngologic clinics of North America
pub_type: 杂志文章,评审
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journal_title:Otolaryngologic clinics of North America
pub_type: 杂志文章,评审
doi:10.1016/j.otc.2003.12.002
更新日期:2004-02-01 00:00:00
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journal_title:Otolaryngologic clinics of North America
pub_type: 杂志文章
doi:
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journal_title:Otolaryngologic clinics of North America
pub_type: 杂志文章
doi:10.1016/j.otc.2006.11.006
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journal_title:Otolaryngologic clinics of North America
pub_type: 杂志文章
doi:
更新日期:1979-05-01 00:00:00
abstract::Carcinoma of the paranasal sinuses is an insidious and relentless disease with a notoriously poor prognosis. Our diagnostic approach and treatment philosophy are outlined. The more recent results are also presented. ...
journal_title:Otolaryngologic clinics of North America
pub_type: 杂志文章
doi:
更新日期:1985-08-01 00:00:00
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journal_title:Otolaryngologic clinics of North America
pub_type: 杂志文章,评审
doi:
更新日期:1989-06-01 00:00:00
abstract::Meniere's disease can be observed uniquely in revisions of the conservative surgical procedure for endolymphatic sac enhancement, which preserves the labyrinth, unlike destructive procedures. Genetic anatomic abnormalities in patients lead to malabsorption of endolymph and symptoms of Meniere's that are reversed by en...
journal_title:Otolaryngologic clinics of North America
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journal_title:Otolaryngologic clinics of North America
pub_type: 杂志文章,评审
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