Abstract：
PURPOSE:The aim was to study the effect of an antibody-mediated response on rat chronic liver rejection. METHODS:Liver transplantation was performed in rats assigned to one of the 3 treatment groups: group A, Brown Norway (BN) to BN + CsA; group B, dark Agouti (DA) to BN; and group C, DA to BN + CsA. In addition to survival and histopathologic assessment, we examined donor-specific antibodies in sera and C4d staining in the transplanted liver. RESULTS:In rats with chronic rejection, high levels of IgG1 were detected from day 7, reaching peak levels at postoperative days 60-90, showing significance compared with the acute rejection (P < .05) and the syngeneic groups (P < .01). There was more C4d deposition in vessels and portal stroma of the livers from recipients displaying chronic rejection compared with recipients showing acute rejection or of syngeneic origin (P < .05). CONCLUSION:Antibody-mediated responses might play important roles in the development of chronic liver allograft rejection.
journal_name
Transplant Procjournal_title
Transplantation proceedingsauthors
Wan R,Ying W,Zeng L,Deng X,Chen H,Gao Ldoi
10.1016/j.transproceed.2011.03.043subject
Has Abstractpub_date
2011-06-01 00:00:00pages
1976-9issue
5eissn
0041-1345issn
1873-2623pii
S0041-1345(11)00482-9journal_volume
43pub_type
杂志文章abstract：:1. A National Transplantation Service has been established at the Alfred Hospital performing more than 50 transplants per year. 2. Increased access to transplantation technology has facilitated an improvement in national population servicing from 2.7 to 6.2 transplants per million population per year. National funding...
journal_title：Transplantation proceedings
pub_type： 杂志文章
doi：
更新日期：1992-10-01 00:00:00
abstract：:Radiation-induced osteosarcoma, its metastasis, and cells grown in tissue culture were karyotyped. Both hypodiploid and hyperdiploid stem lines were observed. The hypodiploid line contained 45-55 chromosomes with 10-15 abnormal metacentric and submetacentric chromosomes and one subtelocentric marker. The hyperdiploid ...
journal_title：Transplantation proceedings
pub_type： 杂志文章
doi：
更新日期：1975-12-01 00:00:00
abstract：INTRODUCTION:Hepatocellular carcinoma (HCC) is the third most common cause of cancer-related death worldwide. Orthotopic liver transplantation (OLT) is the best therapy of choice for early, unresectable HCC. The Hungarian Liver Transplantation Program was launched in 1995 at the Department of Transplantation and Surger...
journal_title：Transplantation proceedings
pub_type： 杂志文章
doi：10.1016/j.transproceed.2015.07.026
更新日期：2015-09-01 00:00:00
abstract：BACKGROUND:The Model for End-Stage Liver Disease (MELD) was introduced in 1999 to quantify the 3-month prognosis of cirrhotic patients after a transjugular intrahepatic portosystemic shunt (TIPS). Because of the imbalance between organ donors and patients on the waiting list, the MELD was adopted by the United States i...
journal_title：Transplantation proceedings
pub_type： 杂志文章
doi：10.1016/j.transproceed.2007.07.023
更新日期：2007-10-01 00:00:00
abstract：BACKGROUND:Research-grade pancreata preserved by the two-layer method (TLM) compared to organs stored with University of Wisconsin (UW) solution prior to islet isolation result in significantly better islet yields. However, it is unknown whether the TLM improves islet yields from pancreata that meet the criteria for th...
journal_title：Transplantation proceedings
pub_type： 杂志文章
doi：10.1016/j.transproceed.2004.04.012
更新日期：2004-05-01 00:00:00
abstract：OBJECTIVE:To study the influence of body mass index (BMI) on mortality and postoperative evolution in our 10-year experience as a lung transplant group. METHODS:The study included 256 lung transplants performed between June 1999 and June 2009. BMI was stratified into 4 groups (<20 kg/m2 underweight, 20-25 normal weigh...
journal_title：Transplantation proceedings
pub_type： 杂志文章
doi：10.1016/j.transproceed.2010.07.078
更新日期：2010-10-01 00:00:00
abstract：BACKGROUND:Recently, preservation using oxygenated perfluorocarbon (the two-layer method) has shown beneficial effects on islet yield and viability. In this paper, we apply this concept on isolation processes to examine the effectiveness of oxygenation. METHODS:Rat pancreata were digested using four different methods:...
journal_title：Transplantation proceedings
pub_type： 杂志文章
doi：10.1016/j.transproceed.2004.12.232
更新日期：2005-01-01 00:00:00
abstract：PURPOSE:The assessment of glomerular filtration rate (GFR) is the most commonly used test of renal function. Cystatin-C, a cysteine protease inhibitor, which can be measured by light-scattering immunoassay, possesses many of the attributes required of the ideal GFR marker. Conversely, many endogenous markers that are w...
journal_title：Transplantation proceedings
pub_type： 杂志文章
doi：10.1016/j.transproceed.2004.06.009
更新日期：2004-07-01 00:00:00
abstract：:Intestinal ischemia-reperfusion (I/R) causes severe organ failure and intense inflammatory responses, which are mediated in part by the cytokine tumor necrosis factor-alpha (TNF-alpha). Bupropion is an antidepressant known to inhibit TNF-alpha production. We sought to examine the protective effects of bupropion on int...
journal_title：Transplantation proceedings
pub_type： 杂志文章
doi：10.1016/j.transproceed.2013.04.010
更新日期：2013-07-01 00:00:00
abstract：PURPOSE:The patent covering mycophenolate mofetil (MMF) in Korea has expired and, thus, several generic MMF agents are now commercially available. The supply of Cellcept (Roche Korea) was interrupted at the end of 2011, so it was inevitable that a generic MMF would be used instead. During this period, we performed a pr...
journal_title：Transplantation proceedings
pub_type： 杂志文章
doi：10.1016/j.transproceed.2013.08.026
更新日期：2013-10-01 00:00:00
abstract：:The Prometheus system is a plasma filtration treatment coupling adsorption and hemodialysis (FPSA) aimed to blood purification in liver failure. After separation through an albumin-permeable membrane, plasma enters a secondary circuit where protein-bound toxic substances are removed by two adsorbers; p01, a neutral re...
journal_title：Transplantation proceedings
pub_type： 杂志文章
doi：10.1016/j.transproceed.2006.02.017
更新日期：2006-05-01 00:00:00
abstract：:The development of posttransplant lymphoproliferative disease (PTLD) is strongly linked to infection with the Epstein-Barr virus (EBV), immunosuppression-state, the type of allograft, and EBV-seronegativity. A 18-month-old girl who had undergone living donor liver transplantation using the left lateral segment from he...
journal_title：Transplantation proceedings
pub_type： 杂志文章
doi：10.1016/j.transproceed.2004.08.077
更新日期：2004-10-01 00:00:00
abstract：BACKGROUND:The Ecuadorian population forms the largest Latin American immigrant group in Spain. However, their knowledge about the brain death (BD) concept and the relationship with the attitude toward organ donation has been little analyzed. The objective of the study is to analyze the knowledge of the BD concept amon...
journal_title：Transplantation proceedings
pub_type： 杂志文章
doi：10.1016/j.transproceed.2019.12.013
更新日期：2020-03-01 00:00:00
abstract：BACKGROUND:This study explored caring difficulties and the reliable coping strategies for pediatric organ transplant recipients (POTR) and their families during their dark recovery experiences (DRE) in the hospital from the perspectives of Taiwan organ transplant health professionals (OTHP) in Taiwan. METHODS:A qualit...
journal_title：Transplantation proceedings
pub_type： 杂志文章,多中心研究
doi：10.1016/j.transproceed.2015.11.019
更新日期：2016-04-01 00:00:00
abstract：:Two young men developed nephrotic syndrome associated with Hodgkin's lymphoma and progressive renal failure. After a short course of hemodialysis with blood transfusion, each received a cadaveric renal transplant. During the postoperative period, chemotherapy (MOPP) was given. No transplant rejection episodes were dia...
journal_title：Transplantation proceedings
pub_type： 杂志文章
doi：
更新日期：1984-10-01 00:00:00
abstract：:Liver transplantation, the only effective treatment for end-stage disease, is limited by donor availability. Cell transplantation offers the possibility to restore liver mass and function. Cryopreserved primary hepatocytes that can be thawed as needed might address this problem. Hepatocytes were harvested from a male ...
journal_title：Transplantation proceedings
pub_type： 杂志文章
doi：10.1016/j.transproceed.2012.03.050
更新日期：2012-05-01 00:00:00
abstract：:Transmission of donor infections to immunosuppressed recipients may produce serious complications. Here, we report two cases of ruptured renal artery pseudoaneurysm within a few months after renal transplantation from a donor with Gorham's syndrome, a rare disease characterized by proliferation of vascular and lymphat...
journal_title：Transplantation proceedings
pub_type： 杂志文章,评审
doi：10.1016/j.transproceed.2004.04.082
更新日期：2004-06-01 00:00:00
abstract：BACKGROUND:Renal transplants from elderly donors have a high incidence of delayed graft function, which can be increased by the initial use of calcineurin inhibitors. Our purpose was to assess the safety and efficacy of an immunosuppressive regimen using anti-IL-2R antibodies and MMF that allows delayed introduction of...
journal_title：Transplantation proceedings
pub_type： 临床试验,杂志文章
doi：10.1016/j.transproceed.2005.02.039
更新日期：2005-04-01 00:00:00
abstract：:Hepatocyte growth factor (HGF) plays a critical role in transplant rejection. Herein we addressed whether HGF expression could be used for accurate and early diagnosis of acute and chronic rejection in cardiac transplantation. We used a heterotopic cardiac transplantation model using nonhuman primates (Macaca fuscata,...
journal_title：Transplantation proceedings
pub_type： 杂志文章
doi：10.1016/j.transproceed.2006.10.075
更新日期：2006-12-01 00:00:00
abstract：OBJECTIVE:To retrospectively evaluate postoperative morphine requirements in healthy living donors undergoing partial hepatectomy and patients with end-stage hepatocellular carcinoma or end-stage liver disease undergoing liver transplantation. PATIENTS AND METHODS:The study included all patients who received intraveno...
journal_title：Transplantation proceedings
pub_type： 杂志文章
doi：10.1016/j.transproceed.2010.02.024
更新日期：2010-04-01 00:00:00
abstract：:There is a worldwide shortage of organs for transplantation; the number of patients on the waiting list exceeds the supply of available organs. The demand for organ donation is particularly concerning in Israel. A new Israeli law has been instituted to give those who sign donor cards allocation priority if they are ev...
journal_title：Transplantation proceedings
pub_type： 杂志文章
doi：10.1016/j.transproceed.2010.09.146
更新日期：2010-12-01 00:00:00
abstract：:Mitral valve dysfunction after orthotopic heart transplantation may cause symptoms refractory to medical therapy. In this report, we present a patient who underwent mitral annuloplasty for severe symptomatic mitral valve insufficiency 9 years after heart transplantation, and we critically appraise the literature avail...
journal_title：Transplantation proceedings
pub_type： 杂志文章
doi：10.1016/j.transproceed.2007.10.010
更新日期：2008-06-01 00:00:00
abstract：:Extracorporeal shock wave lithotripsy (ESWL) is a safe, effective method to treat urinary lithiasis. The success rate in ESWL depends on stone location, size, number, and fragility as well as calceal anatomy and patency of the urinary tract. An association of calcineurin inhibitors and uric acid urolithiasis has been ...
journal_title：Transplantation proceedings
pub_type： 杂志文章
doi：10.1016/j.transproceed.2007.09.042
更新日期：2007-12-01 00:00:00
abstract：BACKGROUND:Platelet-derived growth factor (PDGF) and fibroblast growth factor (FGF) seem to play a key role in immunological reactions shortly after heart transplantation (HTx). The aim of this study was to analyze the time course of the expression of PDGF A and B, PDGF-receptor alpha (PDGF-Ralpha) and beta, aFGF, and ...
journal_title：Transplantation proceedings
pub_type： 杂志文章
doi：10.1016/j.transproceed.2006.12.018
更新日期：2007-03-01 00:00:00
abstract：BACKGROUND:Animal models of partial hepatic ischemia-reperfusion injury (IRI) have potential benefits for decision making and clinical management after liver transplantation or massive hepatic resection. We evaluated changes in apparent diffusion coefficient (ADC) in rabbits with partial hepatic IRI using 3.0 T magneti...
journal_title：Transplantation proceedings
pub_type： 杂志文章
doi：10.1016/j.transproceed.2011.01.183
更新日期：2011-06-01 00:00:00
abstract：PURPOSE:To assess the incidence and management of postoperative abdominal bleeding after orthotopic liver transplantation (OLT) and to identify risk factors for abdominal bleeding. METHODS:We retrospectively reviewed the medical records of 1039 patients who underwent OLT at our institution from January 2008 to Decembe...
journal_title：Transplantation proceedings
pub_type： 杂志文章
doi：10.1016/j.transproceed.2012.01.011
更新日期：2012-04-01 00:00:00
abstract：:Transplantation of vital human organs is a lifesaving therapy for patients with end-stage organ failure who are medically fit to undergo the surgical procedure. However, deceased donor management remains one of the most neglected areas in transplantation medicine. Brainstem death leads to hemodynamic, metabolic, and i...
journal_title：Transplantation proceedings
pub_type： 杂志文章
doi：10.1016/j.transproceed.2008.03.029
更新日期：2008-05-01 00:00:00
abstract：:Pancreatic islet cell transplantation is a promising approach to restore the required mass of functional beta cells in diabetic patients as a means to achieve long-term normoglycemia. This therapy is, however, not yet widely used, in part because of the shortage of human islet cells. Gaining detailed knowledge of the ...
journal_title：Transplantation proceedings
pub_type： 杂志文章
doi：10.1016/j.transproceed.2004.12.050
更新日期：2005-03-01 00:00:00
abstract：:Ischemia-reperfusion injury is of major clinical relevance during liver transplantation. In the present study, the therapeutic efficacy of taurine to protect against ischemia-reperfusion injury was investigated in rabbit livers. We demonstrated that intravenous injection of taurine attenuated liver dysfunction as evid...
journal_title：Transplantation proceedings
pub_type： 杂志文章
doi：10.1016/j.transproceed.2006.02.057
更新日期：2006-06-01 00:00:00
abstract：BACKGROUND:Kidney transplantation (KT) is the optimal treatment for chronic end-stage renal failure. However, it is experiencing a huge delay in Morocco, and the lack of information on this alternative treatment could contribute to this delay. The purpose of our work is to evaluate the knowledge of hemodialysis (HD) on...
journal_title：Transplantation proceedings
pub_type： 杂志文章,多中心研究
doi：10.1016/j.transproceed.2019.01.173
更新日期：2019-09-01 00:00:00
