Nucleotide sequence of VP4 and VP7 genes of human rotaviruses with subgroup I specificity and long RNA pattern: implication for new G serotype specificity.

abstract：:The human cytomegalovirus UL4 gene encodes a 48-kDa glycoprotein, expression of which is repressed at the translational level by a short upstream open reading frame (uORF2) within the UL4 transcript leader. Mutation of the uORF2 initiation codon in the viral genome eliminates ribosomal stalling at the uORF2 terminatio...

journal_title：Journal of virology

authors： Alderete JP,Child SJ,Geballe AP

更新日期：2001-08-01 00:00:00

abstract：:After rabies virus glycoprotein was treated with CNBr, the peptide mixture was fractionated by preparative sodium dodecyl sulfate-polyacrylamide gel electrophoresis. CNBr-cleaved peptide fragments were resolved into seven peptide bands under reducing conditions and six peptide bands under nonreducing conditions. The i...

journal_title：Journal of virology

authors： Dietzschold B,Wiktor TJ,Macfarlan R,Varrichio A

更新日期：1982-11-01 00:00:00

abstract：:Human immunodeficiency virus type 1 (HIV-1) isolates derived directly from clinical samples are usually unable to grow in cytokine-independent continuous cell lines, thus hindering the study of their biological features and their sensitivity to humoral and cellular protective immunity. To overcome these limitations, w...

journal_title：Journal of virology

authors： Lusso P,Cocchi F,Balotta C,Markham PD,Louie A,Farci P,Pal R,Gallo RC,Reitz MS Jr

更新日期：1995-06-01 00:00:00

abstract：:Five gibbon ape leukemia virus substrains (two from gibbons with lymphocytic leukemia and three from gibbons with myelogenous leukemia) were examined for unique genomic sequences specific for each form of leukemia. By using sequential adsorption procedures, the genome from each gibbon ape leukemia virus was fractionat...

journal_title：Journal of virology

authors： Sun L,Kawakami TG

更新日期：1980-08-01 00:00:00

abstract：:The ORF3 protein of hepatitis E virus (HEV) is a multifunctional protein important for virus replication. The ORF3 proteins from human, swine, and avian strains of HEV contain a conserved PXXP amino acid motif, resembling either Src homology 3 (SH3) cell signaling interaction motifs or "late domains" involved in host ...

journal_title：Journal of virology

authors： Kenney SP,Pudupakam RS,Huang YW,Pierson FW,LeRoith T,Meng XJ

更新日期：2012-05-01 00:00:00

abstract：:Recombinant viruses were constructed to have an Escherichia coli replicon containing a mutagenesis marker, the supF gene, integrated within the thymidine kinase locus (tk) of herpes simplex virus type 1. These viruses expressed either wild-type or mutant DNA polymerase (Pol) and were tested in a mutagenesis assay for ...

journal_title：Journal of virology

authors： Hwang YT,Liu BY,Hwang CB

更新日期：2002-04-01 00:00:00

abstract：:Alternative splicing of adeno-associated virus type 2 (AAV2) P19-generated pre-mRNAs generates the small Rep proteins Rep52 and Rep40, which differ in their carboxyl termini. Both proteins are required for optimal packaging of AAV2 genomes. AAV5 Rep-encoding P19-generated transcripts are primarily polyadenylated withi...

journal_title：Journal of virology

authors： Farris KD,Pintel DJ

更新日期：2010-01-01 00:00:00

abstract：:Dactylosporangiophage A1 has a polygonal head (75 nm) with spherical capsomeres (3 nm) and a noncontractile tail (200 by 10 nm) with cross-striations which is terminated with at least three prongs which are used for attachment. It contains double-stranded deoxyribonucleic acid and produces very little lysis. Intracell...

journal_title：Journal of virology

authors： Higgins ML,Lechevalier MP

更新日期：1969-02-01 00:00:00

abstract：:Previous analysis of hepatitis B virus (HBV) indicated base pairing between two cis-acting sequences, the 5' half of the upper stem of epsilon and phi, contributes to the synthesis of minus-strand DNA. Our goal was to identify other cis-acting sequences on the pregenomic RNA (pgRNA) involved in the synthesis of minus-...

journal_title：Journal of virology

authors： Abraham TM,Loeb DD

更新日期：2007-11-01 00:00:00

abstract：UNLABELLED:Woodchuck hepatitis virus (WHV), a close relative of human hepatitis B virus (HBV), has been a key model for disease progression and clinical studies. Sequences of the assembly domain of WHV and HBV core proteins (wCp149 and hCp149, respectively) have 65% identity, suggesting similar assembly behaviors. We r...

journal_title：Journal of virology

authors： Kukreja AA,Wang JC,Pierson E,Keifer DZ,Selzer L,Tan Z,Dragnea B,Jarrold MF,Zlotnick A

更新日期：2014-12-01 00:00:00

abstract：:The CC-chemokines RANTES, macrophage inflammatory protein 1alpha (MIP-1alpha), and MIP-1beta are natural ligands for the CC-chemokine receptor CCR5. MIP-1alpha, also known as LD78alpha, has an isoform, LD78beta, which was identified as the product of a nonallelic gene. The two isoforms differ in only 3 amino acids. LD...

journal_title：Journal of virology

authors： Aquaro S,Menten P,Struyf S,Proost P,Van Damme J,De Clercq E,Schols D

更新日期：2001-05-01 00:00:00

abstract：:Cellular responses to DNA damage are crucial for maintaining genome integrity, virus infection, and preventing the development of cancer. Hepatitis C virus (HCV) infection and the expression of the HCV nonstructural protein NS3 and core protein have been proposed as factors involved in the induction of double-stranded...

journal_title：Journal of virology

authors： Ariumi Y,Kuroki M,Dansako H,Abe K,Ikeda M,Wakita T,Kato N

更新日期：2008-10-01 00:00:00

abstract：:Electron micrographic studies of neuronal axons have produced contradictory conclusions on how alphaherpesviruses are transported from neuron cell bodies to axon termini. Some reports have described unenveloped capsids transported on axonal microtubules with separate transport of viral glycoproteins within membrane ve...

journal_title：Journal of virology

authors： Snyder A,Wisner TW,Johnson DC

更新日期：2006-11-01 00:00:00

abstract：:The membrane-proximal region of the human immunodeficiency virus type 1 (HIV-1) transmembrane protein (TM) is critical for envelope (Env)-mediated membrane fusion and contains the target for broadly reactive neutralizing antibody 2F5. It has been proposed that 2F5 neutralization might involve interaction of its long, ...

journal_title：Journal of virology

authors： Ou W,Lu N,Yu SS,Silver J

更新日期：2006-03-01 00:00:00

abstract：:Satellite RNAs are the smallest infectious agents whose replication is thought to be completely dependent on their helper virus (HV). Here we report that, when expressed autonomously in the absence of HV, a variant of satellite RNA (satRNA) associated with Cucumber mosaic virus strain Q (Q-satRNA) has a propensity to ...

journal_title：Journal of virology

authors： Choi SH,Seo JK,Kwon SJ,Rao AL

更新日期：2012-05-01 00:00:00

abstract：:We identified the transcriptional coactivator FHL2 as a novel target of the human papillomavirus type 16 (HPV-16) E7 oncoprotein, which plays a major role in cell transformation. The interaction with FHL2 is abolished by mutations in conserved regions 1 and 2 and in the C-terminal zinc finger domain of E7, all require...

journal_title：Journal of virology

authors： Campo-Fernández B,Morandell D,Santer FR,Zwerschke W,Jansen-Dürr P

更新日期：2007-01-01 00:00:00

abstract：:Rabies virus nucleoprotein (N) plays vital roles in regulation of viral RNA transcription and replication by encapsidation of the nascent genomic RNA. Rabies virus N is phosphorylated, and previous studies demonstrated that mutation of the phosphorylated serine at position 389 to alanine resulted in reduction of viral...

journal_title：Journal of virology

authors： Wu X,Gong X,Foley HD,Schnell MJ,Fu ZF

更新日期：2002-05-01 00:00:00

abstract：:The APOBEC3 (A3) enzymes, A3G and A3F, are coordinately expressed in CD4+ T cells and can become coencapsidated into HIV-1 virions, primarily in the absence of the viral infectivity factor (Vif). A3F and A3G are deoxycytidine deaminases that inhibit HIV-1 replication by inducing guanine-to-adenine hypermutation throug...

journal_title：Journal of virology

authors： Ara A,Love RP,Follack TB,Ahmed KA,Adolph MB,Chelico L

更新日期：2017-01-18 00:00:00

abstract：:Vaccinia virus, a poxvirus, produces structurally distinct forms of virions for which the immediate events following cell entry are ill-defined. We provide evidence that intracellular mature virus (IMV) enters both permissive and nonpermissive T-cell lines and that introduction of CCR5 into nonpermissive mouse fibrobl...

journal_title：Journal of virology

authors： Rahbar R,Murooka TT,Hinek AA,Galligan CL,Sassano A,Yu C,Srivastava K,Platanias LC,Fish EN

更新日期：2006-07-01 00:00:00

abstract：:Cell extracts from murine A9 or human HeLa cells containing wild-type copies the NS1 polypeptide of minute virus of mice (MVM), produced from a recombinant vaccinia virus, can support the resolution of viral 3' termini from palindromic junction fragments of dimeric, replicative-form MVM DNA. Resolution resulted in the...

journal_title：Journal of virology

authors： Cotmore SF,Nüesch JP,Tattersall P

更新日期：1993-03-01 00:00:00

abstract：:The herpes simplex virus 2 (HSV-2) viral microRNA (miRNA) designated miR-H6 is located upstream of the latency-associated transcript (LAT) promoter region on the strand opposite the LAT. Deletion of the LAT promoter and part of LAT exon 1 abolished HSV-2 miR-H6 expression in acutely and latently infected guinea pig do...

journal_title：Journal of virology

authors： Tang S,Bertke AS,Patel A,Margolis TP,Krause PR

更新日期：2011-05-01 00:00:00

abstract：:A panel of monoclonal antibodies that recognize the two major glycoproteins of bovine viral diarrhea virus (BDV) was used to evaluate the antigenic relationship between cytopathic (CP) and noncytopathic (NCP) viruses isolated from cattle dead or dying from fatal BDV infections. Various unrelated BDV isolates were init...

journal_title：Journal of virology

authors： Corapi WV,Donis RO,Dubovi EJ

更新日期：1988-08-01 00:00:00

abstract：:A versatile green fluorescent protein (GFP) expression cassette containing the replication origins of the monopartite begomovirus Tomato yellow leaf curl Sardinia virus (TYLCSV) is described. Transgenic Nicotiana benthamiana plants containing one copy of the cassette stably integrated into their genome were superinfec...

journal_title：Journal of virology

authors： Morilla G,Castillo AG,Preiss W,Jeske H,Bejarano ER

更新日期：2006-04-01 00:00:00

abstract：:We have demonstrated that a liposomal array of well-ordered trimers enhances B cell activation, germinal center formation, and the elicitation of tier-2 autologous neutralizing antibodies. Previously, we coupled well-ordered cleavage-independent NFL trimers via their C-terminal polyhistidine tails to nickel lipids int...

journal_title：Journal of virology

authors： Bale S,Goebrecht G,Stano A,Wilson R,Ota T,Tran K,Ingale J,Zwick MB,Wyatt RT

更新日期：2017-07-27 00:00:00

abstract：:The glycan shield of the human immunodeficiency virus type 1 (HIV-1) envelope (Env) protein serves as a barrier to antibody-mediated neutralization and plays a critical role in transmission and infection. One of the few broadly neutralizing HIV-1 antibodies, 2G12, binds to a carbohydrate epitope consisting of an array...

journal_title：Journal of virology

authors： Luallen RJ,Lin J,Fu H,Cai KK,Agrawal C,Mboudjeka I,Lee FH,Montefiori D,Smith DF,Doms RW,Geng Y

更新日期：2008-07-01 00:00:00

abstract：:Prior to the introduction of live-attenuated vaccines, mumps virus (MuV) was the leading cause of virus-induced meningitis. Although vaccination has been effective at controlling the disease, the use of insufficiently attenuated strains has been associated with high rates of aseptic meningitis in vaccinees. The molecu...

journal_title：Journal of virology

authors： Lemon K,Rima BK,McQuaid S,Allen IV,Duprex WP

更新日期：2007-08-01 00:00:00

abstract：:Early sensing of viral components or infection-induced tissue damage is a prerequisite for the successful control of pathogenic viruses by the host innate immune system. Recent results from our laboratory show how immune cells use the DNA-sensing machinery to detect intracellular damage generated early during infectio...

journal_title：Journal of virology

authors： Aguirre S,Fernandez-Sesma A

更新日期：2017-06-26 00:00:00

abstract：:Poliovirus proteinase 2A (2Apro) is autocatalytically released from the viral polyprotein by cleavage in cis of a Tyr-Gly dipeptide at its own amino terminus, resulting in separation of the P1 structural and P2-P3 nonstructural protein precursors. A second Ty-Gly dipeptide within 3D polymerase is cleaved by 2Apro in t...

journal_title：Journal of virology

authors： Hellen CU,Lee CK,Wimmer E

更新日期：1992-06-01 00:00:00

abstract：:Our knowledge regarding immune-protective and immunopathogenic events in severe acute respiratory syndrome coronavirus (SARS-CoV) infection is limited, and little is known about the dynamics of the immune response at the primary site of disease. Here, an African green monkey (AGM) model was used to elucidate immune me...

journal_title：Journal of virology

authors： Clay C,Donart N,Fomukong N,Knight JB,Lei W,Price L,Hahn F,Van Westrienen J,Harrod KS

更新日期：2012-04-01 00:00:00

abstract：:The nonstructural protein (NSs) of severe fever with thrombocytopenia syndrome phlebovirus (SFTSV) sequesters TANK-binding kinase 1 (TBK1) into NSs-induced cytoplasmic structures to inhibit the phosphorylation and nuclear translocation of interferon (IFN) regulatory factor 3 (IRF3) and subsequent interferon beta (IFN-...

journal_title：Journal of virology

authors： Moriyama M,Igarashi M,Koshiba T,Irie T,Takada A,Ichinohe T

更新日期：2018-09-12 00:00:00