Abstract：
:We sought to characterize the shifting epidemiology and resource utilization of Lyme disease and associated carditis in US children's hospitals. We hypothesized that the Lyme carditis burden has increased and that hospitalizations for Lyme carditis are costlier than those for Lyme disease without carditis. The PHIS database was queried for Lyme disease encounters between January 1, 2007 and December 31, 2013. Additional diagnostic codes consistent with carditis identified Lyme carditis cases. Demographic, clinical, and resource utilization data were analyzed. All costs were adjusted to 2014 US dollars. Lyme disease was identified in 3620 encounters with 189 (5%) associated with carditis. Lyme disease (360 cases in 2007 vs. 672 in 2013, p = 0.01) and Lyme carditis (17 cases in 2007 vs. 40 in 2013, p = 0.03) both significantly increased in frequency. This is primarily accounted for by their increase within the Midwest region. Carditis frequency among cases of Lyme disease was stable (p = 0.15). Encounters for Lyme carditis are dramatically costlier than those for Lyme disease without carditis [median $9104 (3741-19,003) vs. 922 (238-4987), p < 0.001] The increase in Lyme carditis cases in US children's hospitals is associated with an increased Lyme disease incidence, suggesting that there has not been a change in its virulence or cardiac tropism. The increasing number of serious cardiac events and costs associated with Lyme disease emphasize the need for prevention and early detection of disease and control of its spread.
journal_name
Pediatr Cardioljournal_title
Pediatric cardiologyauthors
Beach CM,Hart SA,Nowalk A,Feingold B,Kurland K,Arora Gdoi
10.1007/s00246-019-02250-9subject
Has Abstractpub_date
2020-02-01 00:00:00pages
258-264issue
2eissn
0172-0643issn
1432-1971pii
10.1007/s00246-019-02250-9journal_volume
41pub_type
杂志文章abstract：:Very young mammals have an impressive cardiac regeneration capacity. In contrast, cardiac regeneration is very limited in adult humans. The hearts of young children have a higher regenerative capacity compared with adults, as, for example, seen after surgical correction of an anomalous left coronary artery arising fro...
journal_title：Pediatric cardiology
pub_type： 杂志文章,评审
doi：10.1007/s00246-015-1120-x
更新日期：2015-04-01 00:00:00
abstract：:It is shown that phosphodiesterase type 5 (PDE5) inhibitors such as sildenafil can modulate pulmonary arterial hypertension (PAH) via increasing the level of guanosine-3,5-cyclic monophosphate (cGMP) and decreases pulmonary artery pressure (PAP). In this study we determined the effectiveness of sildenafil and compared...
journal_title：Pediatric cardiology
pub_type： 临床试验,杂志文章
doi：10.1007/s00246-007-9139-2
更新日期：2008-05-01 00:00:00
abstract：:Congenital heart defects (CHDs) are the leading cause of death in infants under 1 year of age. Aberrations in the expression and function of cardiac transcription factors (TFs) are a major contributor to CHDs. Despite the numerous studies undertaken to functionally characterize these TFs, their exact role in different...
journal_title：Pediatric cardiology
pub_type： 杂志文章
doi：10.1007/s00246-019-02099-y
更新日期：2019-06-01 00:00:00
abstract：:Congenital diverticulum of the left ventricle, a rare malformation, is usually associated with midline thoracoabdominal defect. We describe a case with congenital left ventricular diverticulum presenting as an isolated lesion. The lesion was suspected on two-dimensional echocardiography and was confirmed by cardiac ca...
journal_title：Pediatric cardiology
pub_type： 杂志文章
doi：10.1007/BF02524804
更新日期：1996-07-01 00:00:00
abstract：:Pseudohypertension has often been reported in elderly subjects, but is an unusual phenomenon in children. We report the case of a 5-year-old child who presented with features of Williams syndrome (characterized by elfin facies, supravalvar aortic stenosis, and peripheral pulmonary artery stenosis). Repeated blood pres...
journal_title：Pediatric cardiology
pub_type： 杂志文章
doi：10.1007/BF00796994
更新日期：1993-03-01 00:00:00
abstract：:Arrhythmias in pregnancy are becoming more common given more available and effective medical, ablation and device treatment options. Several changes associated with pregnancy, increased blood volume, cardiac output, and heart rate secondary to an increased sympathetic state, facilitate more frequent occurrences of arr...
journal_title：Pediatric cardiology
pub_type： 杂志文章,评审
doi：10.1007/s00246-015-1232-3
更新日期：2015-10-01 00:00:00
abstract：:The proximal course of an anomalously arising coronary artery is a decisive factor in the surgical approach for tetralogy of Fallot (TOF). Studies have shown that echocardiography provides a good anatomic definition of the ostium and proximal epicardial course of coronary arteries [1, 2]. This report describes a case ...
journal_title：Pediatric cardiology
pub_type： 杂志文章
doi：10.1007/s00246-012-0444-z
更新日期：2013-01-01 00:00:00
abstract：:Novel COstatus system (Transonic Systems, Inc., NY), based on ultrasound dilution (UD), works off in situ arterial and central venous catheters in pediatric patients to measure cardiac output (CO). The purpose of the present study was to validate CO measurement by UD (COUD) with pulmonary artery (PA) thermodilution (C...
journal_title：Pediatric cardiology
pub_type： 杂志文章
doi：10.1007/s00246-011-9915-x
更新日期：2011-06-01 00:00:00
abstract：:With the advent of cardiac magnetic resonance imaging and high-resolution echocardiography, cardiac catheterization is unnecessary in clinical protocols in the "routine" single ventricle patient. Catheterization adds little to clinical care in these cases, and there are significant risks and costs associated with it. ...
journal_title：Pediatric cardiology
pub_type： 杂志文章,评审
doi：10.1007/s00246-004-0960-6
更新日期：2005-03-01 00:00:00
abstract：:Overweight and obesity rates have risen dramatically in the United States, with subsequent detrimental comorbidity risks. The rates for obesity among children with congenital and acquired heart disease have rarely been reported. A retrospective cross-sectional study was conducted to determine the prevalence of overwei...
journal_title：Pediatric cardiology
pub_type： 杂志文章
doi：10.1007/s00246-011-0049-y
更新日期：2012-01-01 00:00:00
abstract：:Branch pulmonary artery stenosis is a common problem in pediatric cardiology. Treatment has included surgery, balloon angioplasty, and balloon expandable stent placement. It was the purpose of this investigation to demonstrate the cost-effectiveness of each of these modes of treatment. From 1983 to 1994 there were 30 ...
journal_title：Pediatric cardiology
pub_type： 杂志文章
doi：10.1007/s002469900195
更新日期：1997-09-01 00:00:00
abstract：:The response to warfarin is highly variable among individuals and such variability is likely to have some genetic basis. We evaluted the effect of VKORC1 polymorphisms on warfarin response among Japanese, taking advantage of its unique population structure in which CYP2C9 *2 and *3 alleles are relatively rare. Thirty-...
journal_title：Pediatric cardiology
pub_type： 杂志文章
doi：10.1007/s00246-005-1150-x
更新日期：2006-11-01 00:00:00
abstract：:Internationally, there have been isolated case reports published of children presenting with dilated cardiomyopathy (DCM) in the setting of undiagnosed rickets. Although there has been an increased prevalence of rickets in the United States, there has been only one documented case of associated DCM. At our institution...
journal_title：Pediatric cardiology
pub_type： 杂志文章
doi：10.1007/s00246-009-9444-z
更新日期：2009-08-01 00:00:00
abstract：:Conotruncal heart defect is a complex form of congenital heart disease and usually has a poor prognosis. Although previous studies have identified several missense variants in GATA4 gene that may cause CTD, it remains unclear whether they are involved in CTD pathogenesis because the study population was limited. The a...
journal_title：Pediatric cardiology
pub_type： 杂志文章
doi：10.1007/s00246-016-1542-0
更新日期：2017-03-01 00:00:00
abstract：:The occurrence of familial heart disease in association with tricuspid atresia is rare. The first reported instance of tricuspid atresia and Ebstein's anomaly in siblings is presented. The presence of these two distinct pathologic variants of tricuspid valve malformations in siblings suggests that these malformations ...
journal_title：Pediatric cardiology
pub_type： 杂志文章
doi：10.1007/s002469900072
更新日期：1996-09-01 00:00:00
abstract：:The aim of the study is to identify reliable quantitative fetal echocardiographic predictors for postnatal development of coarctation (CoA). In this retrospective study, we included 65 fetuses with a prenatally suspected, isolated CoA, born 2010-2018. Dimensions of the cardiac structures, aortic, and ductal arches exp...
journal_title：Pediatric cardiology
pub_type： 杂志文章
doi：10.1007/s00246-020-02509-6
更新日期：2020-12-23 00:00:00
abstract：:This study examined the age-related criteria of signal-averaged electrocardiographic (SA-ECG) parameters in children. SA-ECGs were obtained in 82 healthy volunteers in six groups depending on age (group 1: 1 day to < 1 month; group 2: 1 month to < 1 year; group 3: 1 to < 6 years; group 4: 6 to < 12 years; group 5: 12 ...
journal_title：Pediatric cardiology
pub_type： 杂志文章
doi：10.1007/BF00796320
更新日期：1994-05-01 00:00:00
abstract：:Chylothorax is a well-described complication after cardiothoracic surgery in children. Medical nutritional therapy for chylothorax includes medium-chain triglyceride (MCT) formulas and reduction in enteral long-chain triglyceride intake to reduce chyle production. Human milk is usually eliminated from the diet of infa...
journal_title：Pediatric cardiology
pub_type： 杂志文章
doi：10.1007/s00246-016-1393-8
更新日期：2016-08-01 00:00:00
abstract：:Inferior sinus venosus defects (SVDs) are rare imperfections located in the inferior portion of the atrial septum, leading to an overriding inferior vena cava (IVC) and an interatrial connection. These defects have increased risk of anomalous pulmonary venous return (PAPVR) and often are confused with secundum atrial ...
journal_title：Pediatric cardiology
pub_type： 杂志文章
doi：10.1007/s00246-012-0449-7
更新日期：2013-02-01 00:00:00
abstract：:This report describes the use of cross-sectional imaging--echocardiography and contrast-enhanced computed tomography--to confirm the presence of a foramen-type defect of the left pericardium with herniation of the left atrial appendage. ...
journal_title：Pediatric cardiology
pub_type： 杂志文章
doi：10.1007/BF02263455
更新日期：1987-01-01 00:00:00
abstract：:We present an infant with unusual anatomy and physiology of a persistent left superior vena cava (LSVC). The adverse physiologic consequences of the LSVC were corrected with percutaneous placement of vascular plugs. ...
journal_title：Pediatric cardiology
pub_type： 杂志文章
doi：10.1007/s00246-009-9617-9
更新日期：2010-05-01 00:00:00
abstract：:Postpericardiotomy syndrome is a frequent complication following cardiac surgery. It is characterized by fever, chest pain, pericardial friction rub or pericardial effusion, and laboratory signs of inflammation. Treatment includes the use of nonsteroidal antiinflammatory agents, corticosteroids, and pericardial draina...
journal_title：Pediatric cardiology
pub_type： 杂志文章
doi：10.1007/s00246-007-9025-y
更新日期：2008-03-01 00:00:00
abstract：:The congenital anomaly of aortopulmonary window is rare. Its combination with interruption of the aortic arch has been previously recognized and reported in infants and children. Early and complete repair of such a congenital anomaly may prevent progression to cardiac failure and premature death. We describe the succe...
journal_title：Pediatric cardiology
pub_type： 杂志文章,评审
doi：10.1007/BF02505097
更新日期：1996-03-01 00:00:00
abstract：:Central venous pressure (CVP) measurement is a reliable method for evaluating intravascular volume status and cardiac function, but it is an invasive method that results in some complications such as arterial puncture, pneumothorax, and development of infection. The current study was performed to compare CVP measureme...
journal_title：Pediatric cardiology
pub_type： 杂志文章
doi：10.1007/s00246-007-9067-1
更新日期：2008-03-01 00:00:00
abstract：:We performed a Waterston's anastomosis on a patient with complicated tricuspid atresia when she was two months of age. At age 14 years she required left pneumonectomy for massive, idiopathic hemoptysis. Four months after the pneumonectomy we substituted a modified Fontan anastomosis for the Waterston anastomosis. Rest...
journal_title：Pediatric cardiology
pub_type： 杂志文章
doi：10.1007/BF02238530
更新日期：1991-07-01 00:00:00
abstract：:The reported prenatal detection rates (PDRs) for significant congenital heart disease (sCHD) have been suboptimal, even in the current era. Changes in prenatal ultrasound policy and training may lead to improved prenatal detection of sCHD. This study analyzed the results of a policy to assess fetal cardiac outflow tra...
journal_title：Pediatric cardiology
pub_type： 杂志文章
doi：10.1007/s00246-012-0526-y
更新日期：2013-03-01 00:00:00
abstract：:The original version of the article unfortunately contained an alignment error in Table 1. The correct version of Table 1 is given below. ...
journal_title：Pediatric cardiology
pub_type： 杂志文章,已发布勘误
doi：10.1007/s00246-018-1978-5
更新日期：2019-01-01 00:00:00
abstract：:We report a unique case of tricuspid and pulmonary atresia with idiopathic progressive ductus arteriosus restriction in utero. Diligent predelivery planning and a controlled delivery environment led to a favorable outcome. ...
journal_title：Pediatric cardiology
pub_type： 杂志文章
doi：10.1007/s00246-012-0391-8
更新日期：2013-08-01 00:00:00
abstract：:Rhabdomyoma is the most common primary cardiac tumor in infants and children and is often associated with tuberous sclerosis. Surgical resection may be indicated and, if so, is usually curative. We describe a rhabdomyoma in an infant who presented with severe myocardial ischemia necessitating orthotopic heart transpla...
journal_title：Pediatric cardiology
pub_type： 杂志文章
doi：10.1007/BF00794197
更新日期：1995-07-01 00:00:00
abstract：:Patients with anomalies of the heart frequently suffer from arrhythmias that either are associated with a congenital heart defect or result from the course of the disease. For most of the bradyarrhythmias, appropriate timing of the initiation of treatment is more challenging than its eventual execution. In the case of...
journal_title：Pediatric cardiology
pub_type： 杂志文章,评审
doi：10.1007/s002460010134
更新日期：2000-11-01 00:00:00
