Contributions of the Epstein-Barr virus EBNA1 protein to gastric carcinoma.

abstract：:Proviral clones of human immunodeficiency virus type 1 which contained single amino acid changes in the envelope V3 region were constructed. PCR amplification of Sup-T1 T cells transfected with one such mutant, G312T, revealed low levels of virus that resulted in the generation of a revertant virus, in which an alanin...

journal_title：Journal of virology

authors： Morris JF,Sternberg EJ,Gutshall L,Petteway SR Jr,Ivanoff LA

更新日期：1994-12-01 00:00:00

abstract：:Herpes B virus (BV) naturally infects macaque monkeys and is genetically similar to herpes simplex virus (HSV). Zoonotic infection of humans can cause encephalitis and if untreated has a fatality rate of ∼80%. The frequent use of macaques in biomedical research emphasizes the need to understand the molecular basis of ...

journal_title：Journal of virology

authors： Amen MA,Griffiths A

更新日期：2011-07-01 00:00:00

abstract：:The single-stranded DNA containing the Moloney murine leukemia virus origin for plus-strand synthesis was cloned in M13mp2 and used as a template for avian myeloblastosis virus reverse transcriptase in the presence of Moloney RNA which had been treated with pancreatic RNase A. The RNA pieces containing the polypurine ...

journal_title：Journal of virology

authors： Champoux JJ,Gilboa E,Baltimore D

更新日期：1984-03-01 00:00:00

abstract：:An immunological hierarchy among three H-2Db-restricted cytotoxic T lymphocyte (CTL) determinants in simian virus 40 (SV40) large T antigen (Tag) was described previously: determinants I and II/III are immunodominant, whereas determinant V is immunorecessive. To assess the immunogenicity of each determinant individual...

journal_title：Journal of virology

authors： Fu TM,Mylin LM,Schell TD,Bacik I,Russ G,Yewdell JW,Bennink JR,Tevethia SS

更新日期：1998-02-01 00:00:00

abstract：:Multiple steps of the life cycle of hepatitis B virus (HBV) are known to be coupled to hepatic metabolism. However, the details of involvement of the hepatic metabolic milieu in HBV infection remain incompletely understood. Hepatic lipid metabolism is controlled by a complicated transcription factor network centered o...

journal_title：Journal of virology

authors： Song M,Sun Y,Tian J,He W,Xu G,Jing Z,Li W

更新日期：2018-03-28 00:00:00

abstract：:Revertants of Kirsten sarcoma virus transformed nonproducer BALB/3T3 cells (KA31 cells) were isolated after exposing the transformed cells to 5-fluorodeoxyuridine at high cell density, or when suspended in methylcellulose. Revertants were also isolated by treating KA31 cells with the lectin, concanavalin A, which is m...

journal_title：Journal of virology

authors： Ozanne B,Vogel A

更新日期：1974-08-01 00:00:00

abstract：:Many complex viruses use an assembly pathway in which their genome is packaged into an empty procapsid which subsequently matures into its final expanded form. We utilized Pseudomonas phage 6, a well-established virus assembly model, to probe the plasticity of the procapsid maturation pathway. The 6 packaging nucleosi...

journal_title：Journal of virology

authors： Sun X,Pirttimaa MJ,Bamford DH,Poranen MM

更新日期：2013-12-01 00:00:00

abstract：:To better understand the virological aspect of the expanding AIDS epidemic in southern Africa, a set of 23 near-full-length clones of human immunodeficiency virus type 1 (HIV-1) representing eight AIDS patients from Botswana were sequenced and analyzed phylogenetically. All study viruses from Botswana belonged to HIV-...

journal_title：Journal of virology

authors： Novitsky VA,Montano MA,McLane MF,Renjifo B,Vannberg F,Foley BT,Ndung'u TP,Rahman M,Makhema MJ,Marlink R,Essex M

更新日期：1999-05-01 00:00:00

abstract：:Polydnaviridae is a unique family of DNA viruses that are symbiotically associated with parasitoid wasps. Upon oviposition, wasps inject these viruses into their hosts, where they cause several physiological alterations, including suppression of the cellular immune response. Here we report that expression of the glc1....

journal_title：Journal of virology

authors： Beck M,Strand MR

更新日期：2005-02-01 00:00:00

abstract：:Human trophoblast cells were permissively infected by human cytomegalovirus. The kinetics of viral immediate-early, early, and late gene expression was clearly delayed compared to that in fibroblasts. Productive infection was unequivocally proven by the detection of virion particles, infectious virus in trophoblast cu...

journal_title：Journal of virology

authors： Halwachs-Baumann G,Wilders-Truschnig M,Desoye G,Hahn T,Kiesel L,Klingel K,Rieger P,Jahn G,Sinzger C

更新日期：1998-09-01 00:00:00

abstract：:Amino acid analysis of [3H]proline-labeled polyomavirus major capsid protein VP1 by two-dimensional paper chromatography of the acid-hydrolyzed protein revealed the presence of 3H-labeled hydroxyproline. Addition of the proline analog L-azetidine-2-carboxylic acid to infected mouse kidney cell cultures prevented or gr...

journal_title：Journal of virology

authors： Ludlow JW,Consigli RA

更新日期：1989-06-01 00:00:00

abstract：:Influenza virus particles bind rapidly to vesicular stomatitis, Sindbis, or Rauscher murine leukemia virus particles, forming mixed aggregates demonstrable by electron microscopy. The normal hemagglutinating property of influenza virus is inhibited by these viruses, providing a rapid quantitative assay. Prior treatmen...

journal_title：Journal of virology

authors： Compans RW

更新日期：1974-11-01 00:00:00

abstract：:Protective immunity to rotavirus (RV) is primarily mediated by antibodies produced by RV-specific memory B cells (RV-mBc). Of note, most of these cells express IgM, but the function of this subset is poorly understood. Here, using limiting dilution assays of highly sort-purified human IgM(+) mBc, we found that 62% and...

journal_title：Journal of virology

authors： Narváez CF,Feng N,Vásquez C,Sen A,Angel J,Greenberg HB,Franco MA

更新日期：2012-10-01 00:00:00

abstract：:The vaccinia virus Western Reserve A38L protein is a hydrophobic integral membrane glycoprotein with amino acid similarity to mammalian integrin-associated protein. The protein has an N-terminal immunoglobulin superfamily domain, followed by five membrane-spanning domains and a short cytoplasmic tail. Deletion of the ...

journal_title：Journal of virology

authors： Sanderson CM,Parkinson JE,Hollinshead M,Smith GL

更新日期：1996-02-01 00:00:00

abstract：:A recombinant vesicular stomatitis virus (VSV-PeGFP-M-MmRFP) encoding enhanced green fluorescent protein fused in frame with P (PeGFP) in place of P and a fusion matrix protein (monomeric red fluorescent protein fused in frame at the carboxy terminus of M [MmRFP]) at the G-L gene junction, in addition to wild-type (wt...

journal_title：Journal of virology

authors： Das SC,Panda D,Nayak D,Pattnaik AK

更新日期：2009-03-01 00:00:00

abstract：:Chronic hepatitis B affects over 300 million people who are at risk of developing liver cancer. The basis for the persistence of hepatitis B virus (HBV) in hepatocytes, even in the presence of available antiviral therapies, lies in the accumulation of covalently closed circular DNA (cccDNA) in nuclei of infected cells...

journal_title：Journal of virology

authors： Li M,Sohn JA,Seeger C

更新日期：2017-12-14 00:00:00

abstract：:Extracts from nodavirus-infected Drosophila cells contained detergent-labile 140S "young" particles much richer than mature virions in their content of protein alpha, a precursor of coat proteins beta and gamma. Incorporation studies in infected cells showed that most newly synthesized alpha protein was assembled into...

journal_title：Journal of virology

authors： Gallagher TM,Rueckert RR

更新日期：1988-09-01 00:00:00

abstract：:The human cytomegalovirus (HCMV) UL138 protein downregulates the cell surface expression of the multidrug resistance-associated protein 1 (MRP1) transporter. We examined the genetic requirements within UL138 for MRP1 downregulation. We determined that the acidic cluster dileucine motif is essential for UL138-mediated ...

journal_title：Journal of virology

authors： Gelbmann CB,Kalejta RF

更新日期：2019-05-15 00:00:00

abstract：:Vesicular stomatitis virus has the potential for very rapid evolution in the laboratory, but like many other arboviruses, it evolves at a relatively slow rate in the natural environment. Previous work showed that alternating replication in different cell types does not promote stasis. In order to determine whether oth...

journal_title：Journal of virology

authors： Zárate S,Novella IS

更新日期：2004-11-01 00:00:00

abstract：:Human immunodeficiency virus type 1 (HIV-1) and simian immunodeficiency virus (SIV) particles typically contain small amounts of the surface envelope protein (SU), and this is widely believed to be due to shedding of SU from mature virions. We purified proteins from HIV-1 and SIV isolates using procedures which allow ...

journal_title：Journal of virology

authors： Chertova E,Bess JW Jr,Crise BJ,Sowder II RC,Schaden TM,Hilburn JM,Hoxie JA,Benveniste RE,Lifson JD,Henderson LE,Arthur LO

更新日期：2002-06-01 00:00:00

abstract：:T-cell costimulation molecules B7-1 and B7-2 play an important role in activation of T cells to cytolytic effector function and production of cytokines. Interaction with B7 also causes T cells to upregulate surface molecules, such as CD40L, that effectively stimulate antibody responses in conjunction with cytokines. W...

journal_title：Journal of virology

authors： Thebeau LG,Morrison LA

更新日期：2003-02-01 00:00:00

abstract：:The human immunodeficiency virus Tat protein is essential for virus replication and is a candidate vaccine antigen. Macaques immunized with Tat or chemically modified Tat toxoid having the same clade B sequence developed strong antibody responses. We compared these antisera for their abilities to recognize diverse Tat...

journal_title：Journal of virology

authors： Tikhonov I,Ruckwardt TJ,Hatfield GS,Pauza CD

更新日期：2003-03-01 00:00:00

abstract：:Human metapneumovirus (hMPV) is a leading cause of viral lower respiratory tract infection in children. The sole target of neutralizing antibodies targeting hMPV is the fusion (F) protein, a class I viral fusion protein mediating virus-cell membrane fusion. There have been several monoclonal antibodies (mAbs) isolated...

journal_title：Journal of virology

authors： Bar-Peled Y,Diaz D,Pena-Briseno A,Murray J,Huang J,Tripp RA,Mousa JJ

更新日期：2019-09-12 00:00:00

abstract：:The human adenovirus type 2 (Ad2) mutant Ad2ts111 has previously been shown to contain two mutations which result in a complex phenotype. Ad2ts111 contains a single base change in the early region 1B (E1B) 19,000-molecular-weight (19K) coding region which yields a cyt deg phenotype and another defect which maps to the...

journal_title：Journal of virology

authors： Prelich G,Stillman BW

更新日期：1986-03-01 00:00:00

abstract：:H5N1 highly pathogenic avian influenza virus (HPAIV) has continued to spread and poses a significant threat to both animal and human health. Current influenza vaccine strategies have limitations that prevent their effective use for widespread inoculation of animals in the field. Vaccine strains of Newcastle disease vi...

journal_title：Journal of virology

authors： Ge J,Deng G,Wen Z,Tian G,Wang Y,Shi J,Wang X,Li Y,Hu S,Jiang Y,Yang C,Yu K,Bu Z,Chen H

更新日期：2007-01-01 00:00:00

abstract：:African swine fever virus (ASFV) is a complex, cytoplasmic double-stranded DNA (dsDNA) virus that is currently expanding throughout the world. Currently, circulating virulent genotype II Armenia/07-like viruses cause fatal disease in pigs and wild boar, whereas attenuated strains induce infections with various levels ...

journal_title：Journal of virology

authors： García-Belmonte R,Pérez-Núñez D,Pittau M,Richt JA,Revilla Y

更新日期：2019-05-29 00:00:00

abstract：:The simian virus 40 large T antigen is a promiscuous transcriptional activator of many viral and cellular promoters. We show that the promoter structure necessary for T antigen-mediated transcriptional activation is very simple. A TATA or initiator element is required, in addition to an upstream factor-binding site, w...

journal_title：Journal of virology

authors： Gilinger G,Alwine JC

更新日期：1993-11-01 00:00:00

abstract：:Herpes simplex virus (HSV) entry requires the interaction between the envelope glycoprotein D (gD) and a cellular receptor such as nectin-1 (also named herpesvirus entry mediator C [HveC]) or HveA/HVEM. Nectin-1 is a cell adhesion molecule found at adherens junctions associated with the cytoplasmic actin-binding prote...

journal_title：Journal of virology

authors： Krummenacher C,Baribaud I,Sanzo JF,Cohen GH,Eisenberg RJ

更新日期：2002-03-01 00:00:00

abstract：:Retroviral Gag proteins direct the assembly and release of virus particles from the plasma membrane. The budding machinery consists of three small domains, the M (membrane-binding), I (interaction), and L (late or "pinching-off") domains. In addition, Gag proteins contain sequences that control particle size. For Rous...

journal_title：Journal of virology

authors： Krishna NK,Wills JW

更新日期：2001-07-01 00:00:00

abstract：:Herpesviruses encode a set of core proteins essential for lytic replication of their genomes. Three of these proteins form a tripartite helix-primase complex that, in the case of Epstein-Barr virus (EBV), consists of the helicase BBLF4, the primase BSLF1, and the linker protein BBLF2/3. BBLF2/3 and its homologs in the...

journal_title：Journal of virology

authors： Liao G,Huang J,Fixman ED,Hayward SD

更新日期：2005-01-01 00:00:00