Abstract:
BACKGROUND:We hypothesized that particulate matter (PM) gamma activity (gamma radiation associated with PM) is associated with systemic effects. OBJECTIVE:Examine short-term relationships between ambient and indoor exposures to PM gamma activities with systemic inflammation and endothelial activation in chronic obstructive pulmonary disease (COPD) patients. METHODS:In 85 COPD patients from Eastern Massachusetts, USA from 2012 to 2014, plasma C-reactive protein (CRP), interleukin-6 (IL-6), and soluble vascular cell adhesion molecule-1 (sVCAM-1) were measured seasonally up to four times. We used US EPA RadNet data measuring ambient gamma radiation attached to PM adjusted for background radiation, and estimated in-home gamma radiation exposures using the ratio of in-home-to-ambient sulfur in PM2.5. Linear mixed-effects regression models were used to determine associations between moving averages of PM gamma activities through the week before phlebotomy with these biomarkers. We explored ambient and indoor PM2.5, black carbon (BC), and NO2 as confounders. RESULTS:Ambient and indoor PM gamma activities measured as energy spectra classes 3 through 9 were positively associated with CRP and IL-6. For example, averaged from phlebotomy day through previous 6 days, each IQR increase in indoor PM gamma activity for each spectra class, was associated with an CRP increase ranging from 7.45% (95%CI: 2.77, 12.4) to 13.4% (95%CI: 5.82, 21.4) and for ambient exposures were associated with an increase of 8.75% (95%CI: -0.57, 18.95) to 14.8% (95%CI: 4.5, 26.0). Indoor exposures were associated with IL-6 increase of 3.56% (95%CI: 0.31, 6.91) to 6.46% (95%CI:1.33, 11.85) and ambient exposures were associated with an increase of 0.03% (95%CI: -6.37, 6.87) to 3.50% (95%CI: -3.15, 10.61). There were no positive associations with sVCAM-1. Sensitivity analyses using two-pollutant models showed similar effects. CONCLUSIONS:Our results demonstrate that short-term exposures to environmental PM gamma radiation activities were associated with systemic inflammation in COPD patients.
journal_name
Environ Resjournal_title
Environmental researchauthors
Huang S,Garshick E,Vieira CLZ,Grady ST,Schwartz JD,Coull BA,Hart JE,Laden F,Koutrakis Pdoi
10.1016/j.envres.2019.108841subject
Has Abstractpub_date
2020-01-01 00:00:00pages
108841eissn
0013-9351issn
1096-0953pii
S0013-9351(19)30638-3journal_volume
180pub_type
杂志文章abstract::Pylons of utility lines are commonly used by breeding birds as structures for supporting their nests. Nesting near power lines, however, exposes adult birds and their offspring to the electric and magnetic fields (EMFs) produced by the current. Therefore, we searched for possible relationships between the magnetic fie...
journal_title:Environmental research
pub_type: 杂志文章
doi:10.1016/j.envres.2007.02.006
更新日期:2007-07-01 00:00:00
abstract::The moving bed biofilm reactor (MBBR) has certain advantages, such as high wastewater treatment efficiency, low maintenance and operating costs, and simple operation. It has emerged as a valuable option for small decentralized facilities. The filling ratio, aeration mode and aeration intensity are the main factors tha...
journal_title:Environmental research
pub_type: 杂志文章
doi:10.1016/j.envres.2020.110614
更新日期:2020-12-17 00:00:00
abstract::Wood dust is one of the most common occupational exposures, with about 3.6 million of workers in the wood industry in Europe. Wood particles can deposit in the nose and the respiratory tract and cause adverse health effects. Occupational exposure to wood dust has been associated with malignant tumors of the nasal cavi...
journal_title:Environmental research
pub_type: 杂志文章
doi:10.1016/j.envres.2019.03.058
更新日期:2019-06-01 00:00:00
abstract:BACKGROUND:Congenital limb deficiencies (CLDs) are a relatively common group of birth defects whose etiology is mostly unknown. Recent studies suggest maternal air pollution exposure as a potential risk factor. AIM:To investigate the relationship between ambient air pollution exposure during early pregnancy and offspr...
journal_title:Environmental research
pub_type: 杂志文章
doi:10.1016/j.envres.2019.108716
更新日期:2019-12-01 00:00:00
abstract:BACKGROUND:Traffic-related air pollution (TRAP) exposure has been linked to type 2 diabetes and metabolic dysfunction in humans. Animal studies suggest that air pollutants may alter the composition of the gut microbiota, which may negatively impact metabolic health through changes in the composition and/or function of ...
journal_title:Environmental research
pub_type: 杂志文章
doi:10.1016/j.envres.2017.11.046
更新日期:2018-02-01 00:00:00
abstract::The uranium boom in the United States from the 1940's to the 1980's was a period of extensive uranium mining on Native American lands. However, detailed environmental investigations of the resulting uranium pollution are sparse and typically ignore contributions from airborne particulate matter. The Midnite Mine is a ...
journal_title:Environmental research
pub_type: 杂志文章
doi:10.1016/j.envres.2020.110619
更新日期:2020-12-27 00:00:00
abstract::The adsorption dynamics of common solid sorbents against various pollutant species are yet poorly understood with respect to the retrograde phenomenon in which the relationship between breakthrough vs. pulled volume is characterized by an early unusual trend (initial increase followed by a decrease to a minimum) and b...
journal_title:Environmental research
pub_type: 杂志文章
doi:10.1016/j.envres.2019.108737
更新日期:2019-11-01 00:00:00
abstract::Human cadmium intake derives mainly from food sources, and cadmium can be present in high concentrations in some offal. A meta-analysis using random effects modeling was carried out to integrate the results of 21 controlled randomized trials in which sheep were fed diets with elevated cadmium levels and cadmium concen...
journal_title:Environmental research
pub_type: 杂志文章,meta分析
doi:10.1016/s0013-9351(03)00084-7
更新日期:2004-02-01 00:00:00
abstract::The importance of secondary raw materials for phosphorus (P) fertilizer production is expected to increase in the future due to resource depletion, supply risks, and heavy metal contamination of fossil phosphate resources. Municipal wastewater is a promising source for P recovery. In Germany for instance, it contains ...
journal_title:Environmental research
pub_type: 杂志文章
doi:10.1016/j.envres.2017.02.034
更新日期:2017-05-01 00:00:00
abstract::To assess the elimination of PCBs in humans, PCB concentrations in serum from 165 capacitor manufacturing workers were measured twice within a 46-month interval (March 1976-December 1979). Use of PCBs at the facility was entirely eliminated in 1977. PCB congeners with lower chlorination (LPCBs--mainly tri- and tetrach...
journal_title:Environmental research
pub_type: 杂志文章
doi:10.1016/s0013-9351(05)80240-3
更新日期:1992-10-01 00:00:00
abstract::Traditional food consumption for Indigenous peoples is associated with improved nutrition and health but can also pose potential risks via exposure to contaminants. Polycyclic aromatic hydrocarbons (PAHs) are compounds of interest due to their widespread presence (e.g., their metabolites are detected in up to 100% of ...
journal_title:Environmental research
pub_type: 杂志文章
doi:10.1016/j.envres.2020.109112
更新日期:2020-03-01 00:00:00
abstract::Seawater pollution problems are gaining interest worldwide because of their public health impact and other issues. Levels of pollutants at Gaza Beach determined the only recreational area for the inhabitants of Gaza were recently determined and shown to be high. Five bathing sites in the Middle Camps area along the Ga...
journal_title:Environmental research
pub_type: 杂志文章
doi:10.1016/j.envres.2005.07.005
更新日期:2006-05-01 00:00:00
abstract::Bisphenol A (BPA) and Di-(2-ethylhexyl) phthalate (DEHP) are two wide spread chemicals classified as endocrine disruptors (ED). The present study aims to estimate the non-dietary (dermal, non-dietary ingestion and inhalation) exposure to BPA and DEHP for a pregnant women cohort. In addition, to assess the prenatal exp...
journal_title:Environmental research
pub_type: 杂志文章
doi:10.1016/j.envres.2018.05.008
更新日期:2018-10-01 00:00:00
abstract::Exposure to polycyclic aromatic hydrocarbons (PAHs) was assessed in a cohort of 394 subjects, 198 residing in three small municipalities near a new waste-to-energy (WTE) incinerator located in the Turin area, and 196 residing in neighbouring control areas in the town (of Turin). The assessment of exposure to PAHs was ...
journal_title:Environmental research
pub_type: 杂志文章
doi:10.1016/j.envres.2019.108903
更新日期:2020-02-01 00:00:00
abstract::Chitosan was used as crosslinking agent to load bimetal particles onto bentonite. The Fe-Al bimetal chitosan bentonite (Fe-Al bimetal @ bent) complex was prepared for the efficient removal of nitrate from wastewater and its by-products at low temperature. The samples were characterized by Scanning electron microscope ...
journal_title:Environmental research
pub_type: 杂志文章
doi:10.1016/j.envres.2020.109336
更新日期:2020-05-01 00:00:00
abstract::Concentrations of carbon monoxide (CO) and methane (CH(4)) in air were measured at both urban roadside (U-RS) and urban background (U-BG) stations in Seoul, Korea over an 11 yr period (1996-2006). The overall mean values of CO were 1.16+/-0.63 (U-RS) and 1.08+/-0.77 ppm (U-BG), while those of CH(4) were 2.24+/-0.42 (U...
journal_title:Environmental research
pub_type: 杂志文章
doi:10.1016/j.envres.2010.03.002
更新日期:2010-05-01 00:00:00
abstract::Accurate estimates of spatio-temporal resolved near-surface air temperature (Ta) are crucial for environmental epidemiological studies. However, values of Ta are conventionally obtained from weather stations, which have limited spatial coverage. Satellite surface temperature (Ts) measurements offer the possibility of ...
journal_title:Environmental research
pub_type: 杂志文章
doi:10.1016/j.envres.2015.12.006
更新日期:2016-04-01 00:00:00
abstract::The expected growing population and challenges associated with globalisation will increase local food and feed demands and enhance the pressure on local and regional upland soil resources. In light of these potential future developments it is necessary to define sustainable land use and tolerable soil loss rates with ...
journal_title:Environmental research
pub_type: 杂志文章
doi:10.1016/j.envres.2017.09.020
更新日期:2018-01-01 00:00:00
abstract::Short-term exposure to ambient air pollution is associated with increased cardiovascular mortality and morbidity. This adverse health effect is suggested to be mediated by inflammatory processes. The purpose of this study was to determine if low levels of particulate matter, typical for smaller cities, are associated ...
journal_title:Environmental research
pub_type: 杂志文章
doi:10.1016/j.envres.2012.04.004
更新日期:2012-07-01 00:00:00
abstract::Exposure to PM10 is associated with cardiovascular effects. We evaluated the effects of PM10 on E-Selectin expression and monocytic cell adhesion in human umbilical vein endothelial cells (HUVECs). HUVEC were exposed to PM10 (5-40 microg/cm2) for 6 h, following which surface E-Selectin expression was detected by fluor...
journal_title:Environmental research
pub_type: 杂志文章
doi:10.1016/j.envres.2006.05.004
更新日期:2007-02-01 00:00:00
abstract::The four major trihalomethanes (THMs) found in chlorinated drinking water (CHCl3, CHCl2Br, CHClBr2, and CHBr3) have been investigated for their ability to induce sister chromatid exchanges (SCEs) and cell-cycle delays in human lymphocytes in vitro and to induce SCEs in mouse bone marrow cells in vivo. Each THM tested ...
journal_title:Environmental research
pub_type: 杂志文章
doi:10.1016/0013-9351(83)90193-7
更新日期:1983-10-01 00:00:00
abstract::Fish are a healthy source of protein and nutrients, but contaminants in fish may provide health risks. Determining the risk from contaminants in fish requires site-specific information on consumption patterns. We examine consumption rates for resident and expatriates in the Jeddah region of Saudi Arabia, by species of...
journal_title:Environmental research
pub_type: 杂志文章
doi:10.1016/j.envres.2014.05.014
更新日期:2014-08-01 00:00:00
abstract::Polycyclic aromatic hydrocarbons (PAHs) are priority environmental mutagens and carcinogens that occur in the aquatic environment as mixtures rather than the individual compounds for which guidelines are issued. The present work aimed at understanding the interaction effects between carcinogenic and non-carcinogenic P...
journal_title:Environmental research
pub_type: 杂志文章
doi:10.1016/j.envres.2015.02.010
更新日期:2015-04-01 00:00:00
abstract::The growing human population concentrated in urban areas lead to the increase of road traffic and artificial areas, consequently enhancing air pollution and urban heat island effects, among others. These environmental changes affect citizen's health, causing a high number of premature deaths, with considerable social ...
journal_title:Environmental research
pub_type: 杂志文章
doi:10.1016/j.envres.2017.10.006
更新日期:2018-01-01 00:00:00
abstract::The frequency and severity of flooding events will increase over the coming decades due to global climate change. While close attention has typically been paid to infrastructural and environmental outcomes of flood events, the potential adverse human health consequences associated with post-event consumption from priv...
journal_title:Environmental research
pub_type: 杂志文章
doi:10.1016/j.envres.2021.110707
更新日期:2021-01-08 00:00:00
abstract:BACKGROUND:Ambient air pollution is hypothesized to be a risk factor for hypertensive disorders in pregnancy, one of the major pregnancy complications. Past studies have reported the supporting evidence, however this mainly referred to the Western population, and results from trimester-specific analysis have been varie...
journal_title:Environmental research
pub_type: 杂志文章
doi:10.1016/j.envres.2015.08.024
更新日期:2015-10-01 00:00:00
abstract:BACKGROUND:Epidemiologic studies on the association between metals and body mass index (BMI) have been cross-sectional and have demonstrated inconsistent associations. Our study prospectively examined whether metals measured at baseline were associated with later BMI. We considered metals individually and as joint expo...
journal_title:Environmental research
pub_type: 杂志文章
doi:10.1016/j.envres.2020.109396
更新日期:2020-05-01 00:00:00
abstract::Patterns of mortality in 11 air-conditioned and 9 un-air-conditioned nursing homes in New York City have been investigated to determine the impacts of heat waves on nursing home occupants and the efficacy of air conditioning in reducing these impacts. During each of four heat waves in 1972 and 1973, the number of deat...
journal_title:Environmental research
pub_type: 杂志文章
doi:10.1016/0013-9351(78)90065-8
更新日期:1978-08-01 00:00:00
abstract::Powerful scientific techniques have caused dramatic expansion of genetically modified crops leading to altered agricultural practices posing direct and indirect environmental implications. Despite the enhanced yield potential, risks and biosafety concerns associated with such GM crops are the fundamental issues to be ...
journal_title:Environmental research
pub_type: 杂志文章,评审
doi:10.1016/j.envres.2017.03.011
更新日期:2017-07-01 00:00:00
abstract:BACKGROUND:For many environmental chemicals, concentrations in spot urine samples are considered valid surrogates of exposure and internal dose. To correct for urine dilution, spot urine concentrations are commonly adjusted for urinary creatinine. There are, however, several concerns about the use of urine creatinine. ...
journal_title:Environmental research
pub_type: 杂志文章
doi:10.1016/j.envres.2014.09.009
更新日期:2015-01-01 00:00:00