Changes in PCB serum concentrations among capacitor manufacturing workers.

Abstract:

:To assess the elimination of PCBs in humans, PCB concentrations in serum from 165 capacitor manufacturing workers were measured twice within a 46-month interval (March 1976-December 1979). Use of PCBs at the facility was entirely eliminated in 1977. PCB congeners with lower chlorination (LPCBs--mainly tri- and tetrachlorobiphenyls) had decreased in concentration, with six of the LPCB 7 peaks observed by packed column GC showing average reductions of 25-90%. Higher chlorinated PCBs did not decrease significantly as a whole, although three of the six constituent congener peaks showed some decline (15-25%). As expected, decreases in PCB congener concentrations were associated with chlorine substitution configurations known to be amenable to metabolism.

journal_name

Environ Res

journal_title

Environmental research

authors

Wolff MS,Fischbein A,Selikoff IJ

doi

10.1016/s0013-9351(05)80240-3

subject

Has Abstract

pub_date

1992-10-01 00:00:00

pages

202-16

issue

1

eissn

0013-9351

issn

1096-0953

pii

S0013-9351(05)80240-3

journal_volume

59

pub_type

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