The question of chymase in cultured muscle cells.

abstract：:Nickel (Ni) is widely present in the occupational environment and causes various adverse effects on the human body. Apoptosis induced by Ni2+ may be a key mechanism underlying its toxic effect. In the present study, we investigated the effect of Ni-smelting fumes on cell viability, mitochondrial damage, and apoptosis-...

journal_title：Archives of biochemistry and biophysics

authors： Pan YL,Xin R,Wang SY,Wang Y,Zhang L,Yu CP,Wu YH

更新日期：2018-12-15 00:00:00

abstract：:A putative structural gene cluster containing four open reading frames (ORFs) located downstream of the omp1 gene of Chlamydia trachomatis mouse pneumonitis (MoPn) was cloned and sequenced. A GenBank survey indicated that the identified cluster is similar to the rpsB-tsf-pyrH(smbA)-frr region of Escherichia coli. The ...

journal_title：Archives of biochemistry and biophysics

authors： Zhang Y,Tao J,Zhou M,Meng Q,Zhang L,Shen L,Klein R,Miller DL

更新日期：1997-08-01 00:00:00

abstract：:The C6.5 endoglucanase from Bacillus subtilis catalyzes the hydrolyses of beta-glucans. This enzyme, which is also produced by many ruminant microbes, is not part of the normal digestive repertoire of monogastric animals. We have generated transgenic mice which express the C6.5 endoglucanase gene specifically in the p...

journal_title：Archives of biochemistry and biophysics

authors： Zhang JX,Meidinger R,Forsberg CW,Krell PJ,Phillips JP

更新日期：1999-07-15 00:00:00

abstract：:The polymerization of scallop beta-like actin is significantly slower than that of skeletal muscle alpha-actin. To reveal which steps of polymerization contribute to this difference, we estimated the efficiency of nucleation of the two actins, the rates of filament elongation at spontaneous and gelsolin-nucleated poly...

journal_title：Archives of biochemistry and biophysics

authors： Khaitlina S,Hinssen H

更新日期：2008-09-15 00:00:00

abstract：:Myelin basic protein is known to be released into the circulation following traumatic injuries or demyelination within the central nervous system, resulting in the generation of potentially immunogenic myelin basic protein material. In this investigation we have studied the binding of bovine and human myelin basic pro...

journal_title：Archives of biochemistry and biophysics

authors： Gunnarsson M,Jensen PE

更新日期：1998-11-15 00:00:00

abstract：:The enzyme catalase catalyzes the breakdown of hydrogen peroxide into oxygen and water. It is the main regulator of hydrogen peroxide metabolism. Hydrogen peroxide is a highly reactive small molecule formed as a natural byproducts of energy metabolism. Excessive concentrations may cause significant damages to protein,...

journal_title：Archives of biochemistry and biophysics

authors： Góth L,Nagy T

更新日期：2012-09-15 00:00:00

abstract：:Halogenated and polycyclic aromatic hydrocarbons, exogenous ligands of the aryl hydrocarbon receptor (AhR), cause various toxicological effects through the transformation of the AhR. In this study, we investigated the antagonistic effects of indigoids on the transformation in addition to their agonistic ones. In a cel...

journal_title：Archives of biochemistry and biophysics

authors： Nishiumi S,Yamamoto N,Kodoi R,Fukuda I,Yoshida K,Ashida H

更新日期：2008-02-15 00:00:00

abstract：:A series of peptidyl alpha-keto esters, alpha-keto amides, alpha-keto acids, and alpha-diketones were synthesized which reversibly inhibit papain and cathepsin B. Methyl 3-(N-benzyloxycarbonyl-L-phenylalanyl)amino-2-oxopropionate (a dicarbonyl compound) inhibits papain with a Ki value of 1 microM, whereas the Ki of 3-...

journal_title：Archives of biochemistry and biophysics

authors： Hu LY,Abeles RH

更新日期：1990-09-01 00:00:00

abstract：:Two peptides are specified when the noncoding DNA strand is read in the 5' to 3', or the 3' to 5' direction, and both peptides form strong complexes with the natural peptide, as found by J. E. Blalock and K. L. Bost with ACTH [1986) Biochem. J. 234, 679-683). We report here that strong hydropathic complementarity (pai...

journal_title：Archives of biochemistry and biophysics

authors： Markus G,Tritsch GL,Parthasarathy R

更新日期：1989-08-01 00:00:00

abstract：:An amino acid-sensitive form of chorismate mutase (CM) has been purified over 1000-fold from disks excised from tubers of Solanum tuberosum L. cv White Rose. Purification was accomplished by chromatography on Matrix Blue A followed by affinity chromatography with tryptophan as ligand. CM assays performed in the absenc...

journal_title：Archives of biochemistry and biophysics

authors： Kuroki GW,Conn EE

更新日期：1988-02-01 00:00:00

abstract：:Under a variety of conditions, the permeability of the inner mitochondrial membrane to small solutes can be nonselectively increased. A classic mitochondrial permeability transition (MPT) was originally identified based on its dependence on matrix Ca2+ and its extreme sensitivity to cyclosporin A (CsA). It is now clea...

journal_title：Archives of biochemistry and biophysics

authors： Kushnareva YE,Haley LM,Sokolove PM

更新日期：1999-03-01 00:00:00

abstract：:Angiotensin II (Ang II) plays an important role in inflammatory process. Acute lung injury (ALI), an inflammatory disorder of the lung, is commonly associated with endotoxemia; however, the mechanism that endotoxin (lipopolysaccharide, LPS) induces the inflammatory response in ALI is not well defined. Here, we showed,...

journal_title：Archives of biochemistry and biophysics

authors： Liu L,Qiu HB,Yang Y,Wang L,Ding HM,Li HP

更新日期：2009-01-01 00:00:00

abstract：:Peptaibols are linear non ribosomal peptides which have been the object of intense research efforts regarding their synthesis and the elucidation of the mechanism allowing their insertion in biological membranes. Forty years after their discovery they are still considered as model compounds and suitable probes for the...

journal_title：Archives of biochemistry and biophysics

authors： Das S,Ben Haj Salah K,Djibo M,Inguimbert N

更新日期：2018-11-15 00:00:00

abstract：:Purified human lecithin:cholesterol acyltransferase (LCAT) was covalently labeled by [3H]diisopropylflourophosphate with concomitant loss of enzymatic activity (M. Jauhiainen and P.J. Dolphin (1986) J. Biol. Chem. 261, 7023-7043). Some 60% of the enzyme was labeled in 1 h. Cyanogen bromide (CNBr) cleavage of the label...

journal_title：Archives of biochemistry and biophysics

authors： Farooqui JZ,Wohl RC,Kézdy FJ,Scanu AM

更新日期：1988-03-01 00:00:00

abstract：:DNA of livers or kidneys of rodents contain endogenously modified nucleotides of as yet unknown structure or function. As part of our examination of the origin of endogenous DNA modifications, we examined polar adducts of hamster liver and kidney DNA by 32P-postlabeling analysis (central and upper cuts) and compared t...

journal_title：Archives of biochemistry and biophysics

authors： Wang MY,Liehr JG

更新日期：1995-01-10 00:00:00

abstract：:Ion channel-protein complexes inserted in the membrane act as molecular gates for transport across the membrane. The opening and closing of these gates can be controlled by one or more variables like ligands (small molecules, proteins, etc.), transmembrane voltage, and the concentration gradient of a chemical across t...

journal_title：Archives of biochemistry and biophysics

authors： Banerjee J,Ghosh S

更新日期：2005-03-15 00:00:00

abstract：:Two recombinant sesquiterpene synthases from grand fir, delta-selinene synthase and gamma-humulene synthase, each produce more than 30 sesquiterpene olefins from the acyclic precursor farnesyl diphosphate. These enzymes contain a pair of DDxxD motifs, on opposite lips of the presumptive active site, which are thought ...

journal_title：Archives of biochemistry and biophysics

authors： Little DB,Croteau RB

更新日期：2002-06-01 00:00:00

abstract：:Ovalbumin extracted from oviduct slices incubated with [35S]methionine or [2-3]mannose contained two biosynthetic intermediates, OE and OF (Y. Kato, H. Iwase, and K. Hotta, 1984, J. Biochem. (Tokyo) 95, 455-463). In the present study, these intermediates are further characterized. The 3H dpm/35S dpm ratio of OF labele...

journal_title：Archives of biochemistry and biophysics

authors： Kato Y,Iwase H,Hotta K

更新日期：1986-02-01 00:00:00

abstract：:alpha 1-Acid glycoprotein (alpha 1-AGP) is a glucocorticoid inducible gene product that is synthesized and secreted by certain rat hepatoma tissue culture (HTC) cell lines such as M1.54. Exposure to monensin, a Na+-K+ ionophore, causes a significant redistribution of alpha 1-AGP into two distinct fractions; immunoprec...

journal_title：Archives of biochemistry and biophysics

authors： Haffar OK,Edwards CP,Firestone GL

更新日期：1986-04-01 00:00:00

abstract：:The Oxidative Stress Theory of Aging has had tremendous impact in research involving aging and age-associated diseases including those that affect the nervous system. With over half a century of accrued data showing both strong support for and against this theory, there is a need to critically evaluate the data acquir...

journal_title：Archives of biochemistry and biophysics

authors： Garbarino VR,Orr ME,Rodriguez KA,Buffenstein R

更新日期：2015-06-15 00:00:00

abstract：:Synechococcus sp. strain PCC 7002 is a robust, genetically tractable cyanobacterium that produces six different xanthophyll carotenoids (zeaxanthin, cryptoxanthin, myxoxanthophyll (myxol-2'-fucoside), echinenone, 3'-hydroxyechinenone, and synechoxanthin) and tolerates many environmental stresses, including high light ...

journal_title：Archives of biochemistry and biophysics

authors： Zhu Y,Graham JE,Ludwig M,Xiong W,Alvey RM,Shen G,Bryant DA

更新日期：2010-12-01 00:00:00

abstract：:The cross-reactivity of the monoclonal anti-human placental DNA methyltransferase antibody M2B10 with DNA methyltransferases isolated from other species was investigated. This antibody immunoprecipitates DNA methyltransferases from mammalian cells, i.e., human placenta, mouse P815 cells, and rat liver cells. No cross-...

journal_title：Archives of biochemistry and biophysics

authors： Pfeifer GP,Kohlmaier L,Tomassetti A,Schleicher R,Follmann H,Pfohl-Leszkowicz A,Dirheimer G,Drahovsky D

更新日期：1989-01-01 00:00:00

abstract：:Kinetic analysis has shown that dimethylnitrosamine, dipropylnitrosamine, dibutylnitrosamine, and diphenylnitrosamine initially act as reversible competitive inhibitors with respect to the substrate, acetylthiocholine chloride. The inhibitor constants Ki vary from 21-30 microM for the aliphatic nitrosamines to 8.2 mic...

journal_title：Archives of biochemistry and biophysics

authors： Shuttleworth B,de Villiers DL,Whiteley CG

更新日期：1990-06-01 00:00:00

abstract：:There is dose-dependent Cd(2+)-evoked swelling of isolated rat liver mitochondria energized by complex I, II, or IV respiratory substrates in sucrose medium in the absence of added Ca(2+) and P(i), which is prevented by Sr(2+). Permeability transition effectors (ADP, CsA, EGTA, RR, DTT, ATR, P(i), and Ca(2+)) affect i...

journal_title：Archives of biochemistry and biophysics

authors： Belyaeva EA,Glazunov VV,Korotkov SM

更新日期：2002-09-15 00:00:00

abstract：:Maintenance of genome integrity is essential for the proper function of all cells and organisms. In response to both endogenous and exogenous DNA damaging agents, mammalian cells have evolved a delicate system to sense DNA damage, stop cell cycle progression, modulate cell metabolism, repair damaged DNA, and induce pr...

journal_title：Archives of biochemistry and biophysics

authors： Liu Y,Li Y,Lu X

更新日期：2016-03-15 00:00:00

abstract：:The soluble enzymatic luminescent system of the dinoflagellate Pyrocystis lunula (luciferase-luciferin) is coupled with an enzymatic NAD(P)H-dependent reaction. The enzyme is a soluble reductase (Mr 47,000) which catalyzes, in the presence of NAD(P)H, the reduction of a molecule called P630. Reduced P630 has the same ...

journal_title：Archives of biochemistry and biophysics

authors： Fresneau C,Hill M,Lescure N,Arrio B,Dupaix A,Volfin P

更新日期：1986-12-01 00:00:00

abstract：:Bcl-2 family proteins regulate apoptosis through their homo- and heterodimerization. By protein sequence analysis and structural comparison, we have identified a conserved hydrophobic core at the BH1 and BH2 domains of Bcl-2 family proteins. The hydrophobic core is stabilized by hydrophobic interactions among the resi...

journal_title：Archives of biochemistry and biophysics

authors： Feng Y,Zhang L,Hu T,Shen X,Ding J,Chen K,Jiang H,Liu D

更新日期：2009-04-01 00:00:00

abstract：:Studies in eucaryotic cells (mainly animals and yeast) indicate that at least two DNA polymerases are involved in DNA replication at the level of the replication fork: DNA polymerase alpha, which is associated with DNA primase, is involved in the replication of the lagging strand; DNA polymerase delta, associated with...

journal_title：Archives of biochemistry and biophysics

authors： Richard MC,Litvak S,Castroviejo M

更新日期：1991-05-15 00:00:00

abstract：:FOXP2 is a transcriptional repressor involved in development of the human brain and is the first gene product to be linked to the evolution of human speech. FOXP2 belongs to the FOX superfamily of proteins that share a common winged helix DNA binding domain - the forkhead domain. A divalent cation (Mg2+ or Ca2+) has b...

journal_title：Archives of biochemistry and biophysics

authors： Morris G,Pahad N,Dirr HW,Fanucchi S

更新日期：2018-11-01 00:00:00

abstract：:Heparin infusion in an experimental animal model of arterial injury causes a significant increase in the proteoglycan (PG) component of the extracellular matrix in the injured arteries (Snow, A. D., Bolender, R. P., Wight, T. N., and Clowes, A. W. (1990) Am. J. Pathol. 137, 313-330). The mechanisms responsible for thi...

journal_title：Archives of biochemistry and biophysics

authors： Potter-Perigo S,Wight TN

更新日期：1996-12-01 00:00:00