Endothelio-hematopoietic relationship: getting closer to the beginnings.

Abstract:

:The close association between hematopoietic and endothelial cells during embryonic development led to the proposal that they may originate from a common ancestor--the hemangioblast. Due to a lack of unique specific markers for in vivo cell fate tracking studies, evidence supporting this theory derives mainly from in vitro differentiation studies. Teixeira and colleagues describe a novel enhancer that drives specific eGFP expression in blood islands of the electroporated chick embryo, thereby presenting a tool potentially suitable for analysis of hemangioblast differentiation and development of blood islands.

journal_name

BMC Biol

journal_title

BMC biology

authors

Gordon-Keylock S,Medvinsky A

doi

10.1186/1741-7007-9-88

subject

Has Abstract

pub_date

2011-12-28 00:00:00

pages

88

issn

1741-7007

pii

1741-7007-9-88

journal_volume

9

pub_type

社论
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