Immunotherapy for malignant melanoma.

abstract：:Connections between inflammation and cancer are a rapidly developing field. Some gastrointestinal tract cancers arise from infection, chronic irritation, and ensuing inflammation. Cellular effectors and mediators are important constituents of the tumor microenvironment, including neoplastic, stromal, and migratory hem...

journal_title：Current stem cell research & therapy

authors： Zhang L,Song X,Mohri Y,Qiao L

更新日期：2015-01-01 00:00:00

abstract：:Stem/progenitor cells for cell therapy and regenerative medicine should ideally be available in large numbers, after having been isolated using minimally invasive or non-invasive methodologies. Also, they should exhibit wide differentiation potential into multiple lineages, as well as capability to be used successfull...

journal_title：Current stem cell research & therapy

authors： Eiro N,Fraile M,Schneider J,Vizoso FJ

更新日期：2018-01-01 00:00:00

abstract：:Mesenchymal stem cells are multipotent stromal cells residing within the connective tissue of most organs. Their surface phenotype has been well described. Most commonly, mesenchymal stem cells demonstrate the ability to differentiate into mesenchymal tissues (bone, catailge, fat, etc...), however, under the proper co...

journal_title：Current stem cell research & therapy

authors： Grange S

更新日期：2012-03-01 00:00:00

abstract：:Mesenchymal stem cells (MSCs) have the self-renewal ability and the ability to produce multiple differentiation. Elucidating the genetic circuits that govern MSC self-renewal and differentiation is necessary to improve our comprehension of MSCs and their role in regenerative medicine. microRNAs (miRNAs) play important...

journal_title：Current stem cell research & therapy

authors： Huang C,Gou S,Wang L,Huang K,Liu L,Zhao W,Zheng L,Xiao J

更新日期：2016-01-01 00:00:00

abstract：:Spinal surgery presents a challenge for both neurosurgery and orthopaedic surgery. Due to the heterogeneous differentiation potential of mesenchymal stem cells, there is much interest in the treatment of spine surgery. Animal and human trials focussing on the efficacy of mesenchymal stem cells in spinal cord injury, s...

journal_title：Current stem cell research & therapy

authors： Khan S,Mafi P,Mafi R,Khan W

更新日期：2018-01-01 00:00:00

abstract：:Throughout life, different types of stem cells participate in tissue generation, maintenance, plasticity, and repair. Their abilities to secrete growth factors, to proliferate and differentiate into several cell lineages, and to migrate and home into the damaged tissues have made them attractive candidates for cell th...

journal_title：Current stem cell research & therapy

authors： Ghorbani A,Naderi-Meshkin H

更新日期：2016-01-01 00:00:00

abstract：INTRODUCTION:Retinitis pigmentosa (RP), an inherited disease characterized by progressive loss of photoreceptors and retinal pigment epithelium, is a leading genetic cause of blindness. Cell transplantation to replace lost photoreceptors is a potential therapeutic strategy, but technical limitations have prevented clin...

journal_title：Current stem cell research & therapy

authors： Peng Y,Zhang Y,Huang B,Luo Y,Zhang M,Li K,Li W,Wen W,Tang S

更新日期：2014-03-01 00:00:00

abstract：BACKGROUND:Multiple studies have focused on stem cell-based treatments for rotator cuff disorders; however, the outcomes are not consistent. OBJECTIVES:This systematic review and meta-analysis were performed to evaluate the effects of stem cells on rotator cuff healing. METHODS:A detailed search of relevant studies w...

journal_title：Current stem cell research & therapy

authors： Liu F,Meng Q,Yin H,Yan Z

更新日期：2019-01-01 00:00:00

abstract：AIMS:A systematic review and meta-analysis were performed to explore the clinical outcome of the transplantation of stem cells from various human tissue sources in cirrhotic patients. METHODS:The relevant papers were searched via PubMed, EMBASE, and Cochrane Library databases. Changes in liver function before and afte...

journal_title：Current stem cell research & therapy

authors： Qi X,Guo X,Su C

更新日期：2015-01-01 00:00:00

abstract：:Mesenchymal stem cells (MSCs) have been isolated not only from bone marrow, but also from many other tissues such as adipose tissue, skeletal muscle, liver, brain and pancreas. Because MSC were found to have the ability to differentiate into cells of multiple organs and systems such as bone, fat, cartilage, muscle, ne...

journal_title：Current stem cell research & therapy

authors： Porada CD,Zanjani ED,Almeida-Porad G

更新日期：2006-09-01 00:00:00

abstract：BACKGROUND:Cellular differentiation occurs in a complicated microenvironment containing multiple components including soluble factors and physical cues. In addition to biochemical composition, physical cues are also crucial in determining cellular behaviors. OBJECTIVE:To better understand the interaction between physi...

journal_title：Current stem cell research & therapy

authors： Zhang Q,Lin S,Liao J,Cai X

更新日期：2018-01-01 00:00:00

abstract：:Intervertebral disc (IVD) disorders, especially degenerative disc disease, reduce the quality of life, and are short of effective therapy. A new direction for treatment of chronic tissue and organ diseases is to promote regeneration by harnessing endogenous repair mechanisms. In this review, we discuss the potential o...

journal_title：Current stem cell research & therapy

authors： Li Z,Peroglio M,Alini M,Grad S

更新日期：2015-01-01 00:00:00

abstract：BACKGROUND:Periodontitis is a multifactorial infectious disease that affects a large population worldwide. Oral microorganisms and susceptible host have been proposed to be the prerequisite for the development of periodontitis. Recently, the involvement of epigenetic modifications in the development of periodontitis ha...

journal_title：Current stem cell research & therapy

authors： Luo Y,Peng X,Duan D,Liu C,Xu X,Zhou X

更新日期：2018-01-01 00:00:00

abstract：:The discovery of neural stem cells (NSC) which ensure continuous neurogenesis in the adult mammalian brain, has led to a conceptual revolution in basic neuroscience and to high hopes for clinical nervous tissue repair. However, several research issues remain to address before neural stem cells can be harnessed for reg...

journal_title：Current stem cell research & therapy

authors： Moyse E,Segura S,Liard O,Mahaut S,Mechawar N

更新日期：2008-09-01 00:00:00

abstract：:Since the improvement of chemotherapy and innovation of rituximab, about 60% of patients with diffuse large B cell lymphoma (DLBCL) could receive long-term survival after firstline therapy. Around 30% fail to respond or experience relapse considered as the relapsed/refractory DLBCL, the highdose chemotherapy followed ...

journal_title：Current stem cell research & therapy

authors： Xiao Z,Li J,Miao K

更新日期：2017-01-01 00:00:00

abstract：:Rotator cuff tear causes a high rate of morbidity. After surgical repair, the presence of a scar tissue reduces tendon biomechanical properties. Emerging strategies for enhancing tendon healing are growth factors, cytokines, gene therapy and tissue engineering. However their efficacy has to be proved. Growth factors h...

journal_title：Current stem cell research & therapy

authors： Longo UG,Rizzello G,Berton A,Maltese L,Fumo C,Khan WS,Denaro V

更新日期：2013-11-01 00:00:00

abstract：:Mesenchymal stem cells (MSCs) are ideal candidates for different cellular therapies due to their simple isolation, extensive expansion potential, and low immunogenicity. For various therapeutic approaches, such as bone and cartilage repair, MSCs are expected to replace the damaged tissues by direct differentiation. Ho...

journal_title：Current stem cell research & therapy

authors： Kuang W,Xu X,Lin J,Cao Y,Xu Y,Chen L,Jin L,Tan J

更新日期：2015-01-01 00:00:00

abstract：BACKGROUND:Today, coronary artery disease is still one of the most important causes of mortality despite advanced surgical methods, pharmacotherapies and organ transplantation. These treatment modalities are intended to prevent further progression of myocardial infarction and do not involve the repair of the damaged pa...

journal_title：Current stem cell research & therapy

authors： Aslan A,Allahverdiyev AM,Bagirova M,Abamor ES

更新日期：2018-01-01 00:00:00

abstract：:Due to the nature of articular cartilage of being poorly vascularized the capabilities of self repair are limited. Mesenchymal stem cells transplantation is a modern technique which has been developed after the high success rates obtained by microfracturing and drilling techniques which promote the release of growth f...

journal_title：Current stem cell research & therapy

authors： Martinelli N,Bonifacini C,Longo UG,Marinozzi A,Florio P,Khan WS,Denaro V

更新日期：2013-05-01 00:00:00

abstract：:Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease caused by the selective loss of both spinal and upper motor neurons. One strategy in treating ALS is to use stem cells to replace lost spinal motor neurons. However, transplanted stem cell-derived motor neurons may not survive when exposed to the harsh...

journal_title：Current stem cell research & therapy

authors： Thonhoff JR,Ojeda L,Wu P

更新日期：2009-09-01 00:00:00

abstract：:Reduced-intensity stem cell transplantation (RIST) has opened a new era for hematopoietic stem cell transplantation (HSCT). It was developed based on the knowledge that graft-versus-tumor (GVT) effect is the main anti-tumor effect in allogeneic HSCT. Because RIST is associated with less morbidity and mortality, it can...

journal_title：Current stem cell research & therapy

authors： Kato K,Khaled Y,Mineishi S

更新日期：2007-05-01 00:00:00

abstract：:During the past several years, mesenchymal stem cells (MSCs) derived from adult tissue have rapidly moved from in vitro and animal studies into clinical trials as a therapeutic modality for a diverse group of clinical applications, including head and neck reconstruction. For many diseases, cell therapy could affect th...

journal_title：Current stem cell research & therapy

authors： Hanson S,Thibeault SL,Hematti P

更新日期：2010-09-01 00:00:00

abstract：BACKGROUND:Acute renal failure (ARF) resulting from ischemic or toxic insults remains a major health care problem because of its grave prognosis and the limited effectiveness of available treatment modalities. Current treatment options for ARF are limited to supportive measures and preventive strategies, none of which ...

journal_title：Current stem cell research & therapy

authors： Mohamed MI,Attia FM,Atwa KA

更新日期：2011-12-01 00:00:00

abstract：:Heterogeneity is a well-documented phenomenon in breast cancer; one of the explanations for this phenomenon is the presence of cancer stem cells (CSCs) with the capacity to differentiate along divergent pathways. These CSCs undergo asymmetric and symmetric division resulting in both expansion of the stem cell pool and...

journal_title：Current stem cell research & therapy

authors： Nakshatri H,Srour EF,Badve S

更新日期：2009-01-01 00:00:00

abstract：: ...

journal_title：Current stem cell research & therapy

authors： Yoo JJ

更新日期：2019-01-01 00:00:00

abstract：:Pyrroloquinoline Quinone (PQQ) is the third coenzyme found after niacinamide and flavone nucleotides and is widely present in microorganisms, plants, animals, and humans. PQQ can stimulate the growth of organisms and is very important for the growth, development and reproduction of animals. Owing to the inherent prope...

journal_title：Current stem cell research & therapy

authors： Wen H,He Y,Zhang K,Yang X,Hao D,Jiang Y,He B

更新日期：2020-01-01 00:00:00

abstract：BACKGROUND:Autoimmune disease is a refractory disease. Accumulating Evidence has revealed that the manipulation of mesenchymal stem cells may have the potential to control or even treat autoimmune diseases. Human gingiva-derived mesenchymal stem cells (GMSCs) are emerging as a new line of mesenchymal stem cells that ha...

journal_title：Current stem cell research & therapy

authors： Huang F,Liu ZM,Zheng SG

更新日期：2018-01-01 00:00:00

abstract：:Angiogenesis is a complex process in which capillaries are produced from blood vessels that already exists. Endothelial cells (ECs) and endothelial progenitor cells (EPCs) are pivotal for this process and for the maintenance/restorage of the endothelium. Decreased numbers and dysfunction of these cells have been relat...

journal_title：Current stem cell research & therapy

authors： Sun K,Huang R,Wu S,Chen Z,Deng S,Zhou J,Xie J

更新日期：2016-01-01 00:00:00

abstract：:Recent studies have shown that treatments involving injection of stem cells into animals with damaged cardiac tissue result in improved cardiac functionality. Clinical trials have reported conflicting results concerning the recellularization of post-infarct collagen scars. No clear mechanism has so far emerged to full...

journal_title：Current stem cell research & therapy

authors： Li SC,Acevedo J,Wang L,Jiang H,Luo J,Pestell RG,Loudon WG,Chang AC

更新日期：2012-01-01 00:00:00

abstract：:Stroke is the second most common cause of death and the leading cause of disability in the world. About 30% of the people that are affected by stroke die within a year; 25% of the patients that survive stroke remain in need of care after a year. Therefore, stroke is a major burden for health care costs. The most commo...

journal_title：Current stem cell research & therapy

authors： Zents K,Copray S

更新日期：2016-01-01 00:00:00