当前位置： SCI文献检索 > TRANSPLANTATION PROCEEDINGS期刊下所有文献 > Hepatocellular carcinoma downstaging in liver transplantation.

Hepatocellular carcinoma downstaging in liver transplantation.

Abstract：

BACKGROUND:Hepatocellular carcinoma (HCC) is the leading malignant tumor in Taiwan. The majority of HCC patients are diagnosed in late stages and therefore in eligible for potentially curative treatments. Locoregional therapy has been advocated as an effective treatment for patients with advanced HCCs. PURPOSE:The aim of this study was to evaluate the outcomes of HCC downstaged patients after locoregional therapy to allow eligibility for liver transplantation. METHODS AND MATERIALS:From January 2004 to June 2010, 161 patients with HCCs underwent liver transplantation including 51 (31.6%) who exceeded the University of California-San Francisco (UCSF) who had undergone successful locoregional therapy to be downstaged within these criteria. Among the downstaged patients, 48 (94.1%) underwent transarterial embolization; 7 (13.8%), percutaneous ethanol injection; 24 (47.1%), radiofrequency ablation; 15 (29.4%), surgical resection, and 34 (66.7%), combined treatment. RESULTS:The overall 1- and 5-year survival rates of all HCC patients (n=161) were 93.2% and 80.5%. The overall 1- and 5-year survival rates of downstaged (n=51) versus non-downstaged (n=110) subjects were 94.1% versus 83.7% and 92.7% versus 78.9%, respectively (P=.727). There are 15 (9.2%) HCC recurrences. The overall 1- and 5-year tumor-free rates of all HCC patients were 94.8% and 87.2%. The overall 1- and 5-year tumor-free rates between downstaged versus non-downstaged patients were 93.9% and 90.1% versus 95.2% and 86.0%, respectively (P=.812). CONCLUSION:Patients with advanced HCC exceeding the UCSF/Milan criteria can be downstaged to fit the criteria using locoregional therapy. Importantly, successfully downstaged patients who are transplanted show excellent tumor-free and overall survival rates, similar to fit-criteria group.

journal_name

Transplant Proc

journal_title

Transplantation proceedings

authors

Yu CY,Ou HY,Huang TL,Chen TY,Tsang LL,Chen CL,Cheng YF

doi

10.1016/j.transproceed.2012.01.043

subject

Has Abstract

pub_date

2012-03-01 00:00:00

pages

412-4

issue

2

eissn

0041-1345

issn

1873-2623

pii

S0041-1345(12)00077-2

journal_volume

44

pub_type

杂志文章

相关文献

TRANSPLANTATION PROCEEDINGS文献大全
  • Case Report of Relay Liver Transplantation With Graft Infected With Hepatitis B Virus.

    abstract：:Reuse of liver graft for transplantation is extremely uncommon. We report the 1st case of reuse of liver graft from a recipient who had hepatitis B virus (HBV) infection, 11 years after the 1st transplantation. Our relay liver transplantation challenged conventional thinking because of late reuse of graft in the prese...

    journal_title：Transplantation proceedings

    pub_type： 杂志文章

    doi：10.1016/j.transproceed.2015.09.036

    authors： Wong TC,She WH,Cheung TT,Chan SC,Lo CM

    更新日期：2015-11-01 00:00:00

  • Korean red ginseng: a new approach for the treatment of graft-versus-host disease after liver transplantation.

    abstract：BACKGROUND:Graft-versus-host disease (GVHD) is a rare complication after liver transplantation with an extremely poor prognosis; its occurrence offers great challenges. METHODS:We have reported herein one case of acute GVHD after liver transplantation who was treated with a traditional Chinese medicine named Korean Re...

    journal_title：Transplantation proceedings

    pub_type： 杂志文章

    doi：10.1016/j.transproceed.2011.06.032

    authors： Xu X,Ling Q,Wei Q,Wang K,Zhou B,Zhuang L,Zhou L,Zheng S

    更新日期：2011-09-01 00:00:00

  • A Comparison of the Effects of Sevoflurane and Desflurane on Corrected QT Interval Prolongation in Patients Undergoing Living Donor Liver Transplantation: A Prospective Observational Study.

    abstract：BACKGROUND:QT interval prolongation has frequently been observed in patients with advanced liver disease. We investigated the influence of inhalation anesthetics on the corrected QT (QTc) interval prolongation during surgery in patients undergoing living-donor liver transplantation. METHODS:Our study included 43 patie...

    journal_title：Transplantation proceedings

    pub_type： 杂志文章

    doi：10.1016/j.transproceed.2015.12.034

    authors： Min JJ,Lee J,Lee HC,Ryu HG,Shin M,Kim HJ

    更新日期：2016-01-01 00:00:00

  • Corrected flow time is a good indicator for preload responsiveness during living donor liver donation.

    abstract：BACKGROUND:Corrected flow time (FTc) has been utilized as preload indicator in recent literature. Accurate estimation of preload status during living donor liver donation (LDLD) is important due to fluid restriction. We evaluate the effectiveness of FTc as a surrogate of preload indicator during LDLD. MATERIALS AND ME...

    journal_title：Transplantation proceedings

    pub_type： 杂志文章

    doi：10.1016/j.transproceed.2013.11.021

    authors： Su BC,Luo CF,Chang WY,Lee WC,Lin CC

    更新日期：2014-04-01 00:00:00

  • The malononitrilamide FK778 inhibits activation of NF-kappaB in human dendritic cells.

    abstract：:FK778, a derivative of the active leflunomide-metabolite, A77 1726, has been shown to be a powerful immunosuppressant in several transplantation models, particularly efficient in prevention of chronic allograft rejection. However, the cellular and molecular mechanisms underlying these effects of FK778 have not been in...

    journal_title：Transplantation proceedings

    pub_type： 杂志文章

    doi：10.1016/j.transproceed.2005.03.079

    authors： Zeyda M,Stuhlmeier KM,Kirsch B,Watschinger B,Hörl WH,Stulnig TM,Säemann MD

    更新日期：2005-05-01 00:00:00

  • Posttransplant diabetes mellitus: incidence and risk factors.

    abstract：UNLABELLED:Posttransplant diabetes mellitus (PTDM) is common post transplantation and is associated with tacrolimus (TAC) and steroid therapy. The aim of the present study was to analyze the incidences of PTDM and associated risk factors. METHODS:We selected renal transplant recipients treated with TAC, mycophenolate ...

    journal_title：Transplantation proceedings

    pub_type： 杂志文章

    doi：10.1016/j.transproceed.2008.03.018

    authors： Mazali FC,Lalli CA,Alves-Filho G,Mazzali M

    更新日期：2008-04-01 00:00:00

  • Incidence and risk factors of new-onset diabetes mellitus after renal transplantation.

    abstract：PURPOSE:New-onset diabetes mellitus (PTDM), a major metabolic complication after renal transplantation, examined for incidence and risk factors. METHODS:The records of 358 renal transplant recipients with functioning grafts, from 1986 to 2006, were categorized into two groups according to the usage of tacrolimus (FK):...

    journal_title：Transplantation proceedings

    pub_type： 杂志文章

    doi：10.1016/j.transproceed.2008.06.034

    authors： Chien YS,Chen YT,Chuang CH,Cheng YT,Chuang FR,Hsieh H

    更新日期：2008-09-01 00:00:00

  • Candida-associated denture stomatitis in patients after immunosuppression therapy.

    abstract：:Patients who undergo kidney or liver transplantation receive long-lasting immunosuppressive therapy. The resultant unfavorable symptoms result from immune deficiency and the side effects of the medications. The aim of this study was to establish the frequency and intensity of denture stomatitis and oral candidiasis am...

    journal_title：Transplantation proceedings

    pub_type： 杂志文章

    doi：10.1016/j.transproceed.2005.12.078

    authors： Golecka M,Ołdakowska-Jedynak U,Mierzwińska-Nastalska E,Adamczyk-Sosińska E

    更新日期：2006-01-01 00:00:00

  • Cyclosporine monitoring in stable, long-term, pediatric kidney transplant recipients: the value of C2 determination.

    abstract：:Although a generalized consensus has been reached for therapeutic drug monitoring of cyclosporine microemulsion in adult transplant patients, clear guidelines are recently not available for the pediatric population. In this retrospective analysis of pharmacokinetic data obtained from stable, long-term, pediatric kidne...

    journal_title：Transplantation proceedings

    pub_type： 杂志文章

    doi：10.1016/j.transproceed.2004.03.010

    authors： Ferraresso M,Ghio L,Tirelli S,Pedotti P,Taioli E,Edefonti A,Berardinelli L

    更新日期：2004-04-01 00:00:00

  • Biomarkers for the diagnosis of the stable kidney transplant and chronic transplant injury using the ProtoArray® technology.

    abstract：:Transplant glomerulopathy (TG), a form of chronic renal transplant rejection, carries a poor prognosis. It must be differentiated from the entity defined by the Banff '05 classification, interstitial fibrosis/tubular atrophy (IF/TA). Sequential transplant biopsies have shown that these lesions are subclinical long bef...

    journal_title：Transplantation proceedings

    pub_type： 杂志文章

    doi：10.1016/j.transproceed.2010.09.006

    authors： Le Roux S,Devys A,Girard C,Harb J,Hourmant M

    更新日期：2010-11-01 00:00:00

  • Intrabronchial instillation of amphotericin B lipid complex: a case report.

    abstract：OBJECTIVE:We sought to present our results of topical intrabronchial installation of amphotericin B lipid complex (AmpB lipid). PATIENT AND METHODS:A deposit of fungal material was observed in a bilateral lung transplant recipient who experienced stenosis of the left anastomosis and have been fitted with a double endo...

    journal_title：Transplantation proceedings

    pub_type： 杂志文章

    doi：10.1016/j.transproceed.2009.06.017

    authors： Morales P,Galán G,Sanmartín E,Monte E,Tarrazona V,Santos M

    更新日期：2009-07-01 00:00:00

  • De novo cancer occurrence after renal transplantation: a medical center experience in Taiwan.

    abstract：INTRODUCTION:Renal transplantation has been advocated as the treatment of choice for end-stage renal disease. Organ transplantation increases the incidence of cancer through unclear mechanisms. A literature review showed that the most common neoplasms are of skin origin, which are uncommon in Eastern people. We reviewe...

    journal_title：Transplantation proceedings

    pub_type： 杂志文章

    doi：10.1016/j.transproceed.2004.08.013

    authors： Chiang YJ,Chen CH,Wu CT,Chu SH,Chen Y,Liu KL,Chen SW,Chuang CK

    更新日期：2004-09-01 00:00:00

  • Renal transplantation from cadaveric donor after myocardial revascularization: still a matter of concern?

    abstract：:Renal transplantation in patients who have undergone coronary revascularization remains a matter of concern, few experiences have been reported in literature. From January 1997 to March 2003, 23 previously revascularized patients underwent renal transplants from cadaveric donors. We analyzed patient survival and cardi...

    journal_title：Transplantation proceedings

    pub_type： 杂志文章

    doi：10.1016/j.transproceed.2004.09.079

    authors： Segoloni GP,Quaglia M,Giacosa C,Ferro M,Martina G,Piccoli GB

    更新日期：2004-11-01 00:00:00

  • Knowledge of Chronic Hemodialysis Patients on Kidney Transplantation in Morocco.

    abstract：BACKGROUND:Kidney transplantation (KT) is the optimal treatment for chronic end-stage renal failure. However, it is experiencing a huge delay in Morocco, and the lack of information on this alternative treatment could contribute to this delay. The purpose of our work is to evaluate the knowledge of hemodialysis (HD) on...

    journal_title：Transplantation proceedings

    pub_type： 杂志文章,多中心研究

    doi：10.1016/j.transproceed.2019.01.173

    authors： Karimi F,Chafai M,Fadili W,Laouad I,Lisri M,Habiballah M,Berrada M,Kaitouni AI

    更新日期：2019-09-01 00:00:00

  • Liver transplantation for biliary atresia in Taiwan: a national study.

    abstract：:A national database for orthotopic liver transplantation (OLT) among biliary atresia (BA) cases in Taiwan has not been reported. Using the National Health Insurance (NHI) database to investigate the prognostic features of patients with BA receiving OLT, we studied the prognosis of this procedure for BA. The NHI in Tai...

    journal_title：Transplantation proceedings

    pub_type： 杂志文章

    doi：10.1016/j.transproceed.2008.07.136

    authors： Tiao MM,Yang CY,Tsai SS,Chen CL,Kuo HW

    更新日期：2008-12-01 00:00:00

  • An exploratory study on pharmacogenetics of inosine-monophosphate dehydrogenase II in peripheral mononuclear cells from liver-transplant recipients.

    abstract：:Mycophenolate mofetil (MMF) is an immunosuppressant used for the prophylaxis of rejection in renal, pancreas, and liver transplantation. It inhibits the inducible isoform of the enzyme inosine-monophosphate dehydrogenase (IMPDH II) via its active metabolite mycophenolic acid (MPA). IMPDH II is necessary for de novo pu...

    journal_title：Transplantation proceedings

    pub_type： 杂志文章

    doi：10.1016/j.transproceed.2004.09.070

    authors： Vannozzi F,Filipponi F,Di Paolo A,Danesi R,Urbani L,Bocci G,Catalano G,De Simone P,Mosca F,Del Tacca M

    更新日期：2004-11-01 00:00:00

  • Risk factors and outcomes analyses at 36 months of a prospective, randomized, multicenter, trial of daclizumab induction in simultaneous kidney-pancreas transplant recipients.

    abstract：UNLABELLED:The purpose of this study was to analyze risk factors for acute rejection (AR) and long-term outcomes in simultaneous kidney-pancreas transplant (SKPT) patients enrolled in a prospective, multicenter study of daclizumab (DAC) versus no antibody induction. METHODS:A total of 298 SKPT patients were randomized...

    journal_title：Transplantation proceedings

    pub_type： 杂志文章,多中心研究,随机对照试验

    doi：10.1016/j.transproceed.2005.09.061

    authors： Stratta RJ,Alloway RR,Lo A,Hodge EE

    更新日期：2005-10-01 00:00:00

  • Quality of life of living kidney donors: a single-center experience.

    abstract：:Renal transplantation improves the quality of life (QoL) of patients with end-stage renal disease. The preservation of QoL of living kidney donors is paramount. The aim of this study was to assess the QoL pre- and postdonation using Medical Outcome Survey Short Form-36 (SF-36) and to compare with a control group of po...

    journal_title：Transplantation proceedings

    pub_type： 杂志文章

    doi：10.1016/j.transproceed.2008.03.132

    authors： Shrestha A,Shrestha A,Vallance C,McKane WS,Shrestha BM,Raftery AT

    更新日期：2008-06-01 00:00:00

  • ATG-Fresenius inhibits blood circulating cell proliferation in a dose-dependent manner: an experimental study.

    abstract：INTRODUCTION:Antithymocyte globulin (ATG)-Fresenius (Neovii-Biotech, Graefelfing, Germany), a highly purified rabbit polyclonal antihuman T-lymphocyte immunoglobulin resulting from immunization of rabbits with the Jurkat T-lymphoblast cell line, is currently used for the prevention of acute rejection in patients receiv...

    journal_title：Transplantation proceedings

    pub_type： 杂志文章

    doi：10.1016/j.transproceed.2014.07.016

    authors： Werner I,Seitz-Merwald I,Kiessling AH,Kur F,Beiras-Fernandez A

    更新日期：2014-11-01 00:00:00

  • Computed Tomography as Primary Screening for Appraisal of Pulmonary Small Nodules in Liver Transplant Candidates.

    abstract：BACKGROUND:Chest computed tomography (CT) as a primary screening method in candidates for living donor liver transplantation (LDLT) is not yet a standardized procedure. The aim of this study is to present our methods and result of evaluation of pulmonary small nodules (PSN) after CT as a primary screening tool. PATIEN...

    journal_title：Transplantation proceedings

    pub_type： 杂志文章

    doi：10.1016/j.transproceed.2015.08.046

    authors： Wu YJ,Lin CC,Chang YM,Wang SH,Lin YH,Lu HI,Concejero AM,Chen CL,Lin TL

    更新日期：2016-05-01 00:00:00

  • Cryopreservation of insulin-producing cells microencapsulated in sodium cellulose sulfate.

    abstract：INTRODUCTION:Diabetes mellitus may be treated with pancreatic islet cell transplantation. The use of xenogenic islet cells may overcome the shortage of human donor organs. Microencapsulation seems to be a promising method for immunoprotection. Since isolation, purification, encapsulation, and transplantation of islet c...

    journal_title：Transplantation proceedings

    pub_type： 杂志文章

    doi：10.1016/j.transproceed.2006.08.188

    authors： Stiegler PB,Stadlbauer V,Schaffellner S,Halwachs G,Lackner C,Hauser O,Iberer F,Tscheliessnigg K

    更新日期：2006-11-01 00:00:00

  • Improvement in the care of patients with kidney transplant failure: recommendations of the Spanish Society of Nephrology.

    abstract：:Although long-term outcomes have improved, graft loss caused by chronic allograft nephropathy remains an important obstacle. This situation, together with the progressive increase in the number of renal transplant patients, means that the population of transplant patients readmitted to a dialysis program will be progr...

    journal_title：Transplantation proceedings

    pub_type： 杂志文章

    doi：10.1016/j.transproceed.2009.06.135

    authors： Fernandez Fresnedo G

    更新日期：2009-07-01 00:00:00

  • Complete regression of cutaneous B-cell lymphoma in a renal transplant patient after conversion from cyclosporin to sirolimus.

    abstract：:Posttransplant lymphoproliferative disease remains a serious morbidity. Herein we have reported a case of complete regression of a biopsy-proven B-cell lymphoma that occurred in the posttransplant period. A 48-year-old man received a living donor renal transplant for end-stage renal disease due to undetermined etiolog...

    journal_title：Transplantation proceedings

    pub_type： 杂志文章

    doi：10.1016/j.transproceed.2007.03.092

    authors： Mohsin N,Budruddin M,Kamble P,Khalil M,Pakkyarra A,Jha A,Mohammed E,Ahmed H,Ahmed J,Thomas S,Campistol JM,Daar A

    更新日期：2007-05-01 00:00:00

  • Impact of live donor age (>or=50) on liver transplantation.

    abstract：BACKGROUND:The question of whether donor age negatively impacts recipient outcome in adult-to-adult living donor liver transplantation (LDLT) is rarely discussed. The aim of this study was to evaluate the impact of older donor age (50 years or older) on recipient outcomes in adult-to-adult LDLT. METHODS:LDLT data were...

    journal_title：Transplantation proceedings

    pub_type： 杂志文章

    doi：10.1016/j.transproceed.2007.03.116

    authors： Akamatsu N,Sugawara Y,Tamura S,Kaneko J,Matsui Y,Togashi J,Makuuchi M

    更新日期：2007-12-01 00:00:00

  • A laparoscopic approach to allograft nephrectomy and bilateral native nephrectomy: a case report.

    abstract：INTRODUCTION:Laparoscopic surgery is rapidly emerging as the standard of care for a variety of urological conditions, even among patients who have undergone prior renal transplantation. We describe the technique of bilateral native nephrectomy and allograft nephrectomy by laparoscopy. CASE REPORT:A 32-year-old man wit...

    journal_title：Transplantation proceedings

    pub_type： 杂志文章

    doi：10.1016/j.transproceed.2005.03.108

    authors： Branco AW,Filho AJ,Kondo W,De George MA,Rangel M,De Carvalho RM,Noda RW

    更新日期：2005-06-01 00:00:00

  • Clinical trial of Tripterygium Wilfordii Hook F. in human kidney transplantation in China.

    abstract：OBJECTIVE:In this study, the effects of Triptergium Wilfordii Hook F.(T II) were assessed on human kidney allograft rejection and long-term survival. METHODS:This study compared treatment with T II(T II group, n=121) to that without T II(control group, n=102) among adult first cadaveric renal transplant recipients. Th...

    journal_title：Transplantation proceedings

    pub_type： 杂志文章

    doi：10.1016/j.transproceed.2006.03.017

    authors： Ji SM,Wang QW,Chen JS,Sha GZ,Liu ZH,Li LS

    更新日期：2006-06-01 00:00:00

  • Wilson Disease With Giant Splenic Artery Aneurysms Caused by Fibromuscular Dysplasia During Living Donor Liver Transplantation: A Case Report.

    abstract：:Liver cirrhosis can cause splenic artery aneurysms (SAA) that pose a threat to patients undergoing liver transplantation. However, liver transplantation with multiple visceral artery aneurysms including giant SAA caused by arterial fragility has never been reported. We describe a 36-year-old man with decompensated liv...

    journal_title：Transplantation proceedings

    pub_type： 杂志文章

    doi：10.1016/j.transproceed.2019.06.005

    authors： Sakamoto K,Ogawa K,Tamura K,Ueno Y,Inoue H,Nakamura T,Watanabe J,Takai A,Tohyama T,Senba H,Yoshida O,Abe M,Hiasa Y,Kitazawa R,Kitazawa S,Takada Y

    更新日期：2019-11-01 00:00:00

  • How reconstructive transplantation is different from organ transplantation--and how it is not.

    abstract：:An evolution of understanding and knowledge gained over more than 100 years in the field of solid organ transplantation (SOT) led to the first successful clinical cases of composite tissue allotransplantation. In many ways reconstructive transplantation (RT) is similar to SOT; however, certain characteristics make thi...

    journal_title：Transplantation proceedings

    pub_type： 杂志文章,评审

    doi：10.1016/j.transproceed.2011.08.044

    authors： Hautz T,Brandacher G,Engelhardt TO,Pierer G,Lee WP,Pratschke J,Schneeberger S

    更新日期：2011-11-01 00:00:00

  • Improvement of mortality rate and decrease in histologic hepatic injury after human cord blood stem cell infusion in a murine model of hepatotoxicity.

    abstract：BACKGROUND AND AIMS:Because of their plasticity potential local and systemic application of cord blood stem cells may represent excellent candidates for cell-based therapeutic strategies in toxic liver injuries. It is already known that intraperitoneal administration of hematopoietic stem cells provides rapid liver hom...

    journal_title：Transplantation proceedings

    pub_type： 杂志文章

    doi：10.1016/j.transproceed.2005.06.002

    authors： Di Campli C,Piscaglia AC,Rutella S,Bonanno G,Vecchio FM,Zocco MA,Monego G,Michetti F,Mancuso S,Pola P,Leone G,Gasbarrini G,Gasbarrini A

    更新日期：2005-07-01 00:00:00

  • "Real-time" assessment of human islet preparations with confocal live cell imaging.

    abstract：:Pancreatic islet cell transplantation is a promising approach to restoring normoglycemia in diabetic patients. The outcome of islet transplantation is uncertain for two reasons: The quality of isolated islets is still poorly defined and the functional potential of transplanted islets is difficult to predict. Therefore...

    journal_title：Transplantation proceedings

    pub_type： 杂志文章

    doi：10.1016/j.transproceed.2005.09.076

    authors： Hermann M,Pirkebner D,Draxl A,Margreiter R,Hengster P

    更新日期：2005-10-01 00:00:00