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Case Report of Relay Liver Transplantation With Graft Infected With Hepatitis B Virus.

Abstract：

:Reuse of liver graft for transplantation is extremely uncommon. We report the 1st case of reuse of liver graft from a recipient who had hepatitis B virus (HBV) infection, 11 years after the 1st transplantation. Our relay liver transplantation challenged conventional thinking because of late reuse of graft in the presence of HBV infection. Moreover, both the 1st and the 2nd donors were of advanced age. The key questions were whether the liver graft could be reused safely, especially in the setting of HBV infection, and technical concerns during organ procurement and implantation. The absence of HBV replication was confirmed with negative hepatitis B surface antigen and undetectable serum HBV DNA in the 2nd donor. Based on our experience in managing HBV infection after liver transplantation, we were confident that the adequately suppressed HBV infection in the donor would not jeopardize graft function and that the graft would be able to withstand another ischemia-perfusion injury to continue to function well in our recipient.

journal_name

Transplant Proc

journal_title

Transplantation proceedings

authors

Wong TC,She WH,Cheung TT,Chan SC,Lo CM

doi

10.1016/j.transproceed.2015.09.036

subject

Has Abstract

pub_date

2015-11-01 00:00:00

pages

2768-70

issue

9

eissn

0041-1345

issn

1873-2623

pii

S0041-1345(15)00900-8

journal_volume

47

pub_type

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