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Corrected flow time is a good indicator for preload responsiveness during living donor liver donation.

Abstract：

BACKGROUND:Corrected flow time (FTc) has been utilized as preload indicator in recent literature. Accurate estimation of preload status during living donor liver donation (LDLD) is important due to fluid restriction. We evaluate the effectiveness of FTc as a surrogate of preload indicator during LDLD. MATERIALS AND METHODS:Twenty-five patients undergoing LDLD were enrolled in the study. Administration of intravenous fluid was restricted before lobectomy was performed. After the organ was harvest, fluid challenge with 500 mL of Voluven (130/0.42, Fresenius, Friedberg, Germany) was performed. Stroke volume (SV) was measured with ultrasonic cardiac output monitor (USCOM; USCOM Pty, Ltd, Sydney, Australia) before and after the fluid challenge. The FTc value obtained with USCOM before fluid challenge was recorded. Fluid responsiveness was defined as an increase in SV of more than 15%. Receiver operating characteristic (ROC) curve was performed. RESULTS:The area under ROC curve was 0.9. The optimal cutoff FTc value was 340 milliseconds during LDLD. CONCLUSIONS:FTc is a noninvasive, easily obtainable, and essentially good preload indicator during LDLD.

journal_name

Transplant Proc

journal_title

Transplantation proceedings

authors

Su BC,Luo CF,Chang WY,Lee WC,Lin CC

doi

10.1016/j.transproceed.2013.11.021

subject

Has Abstract

pub_date

2014-04-01 00:00:00

pages

672-4

issue

3

eissn

0041-1345

issn

1873-2623

pii

S0041-1345(13)01225-6

journal_volume

46

pub_type

杂志文章

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