Abstract:
OBJECTIVES:The aim of this study was to investigate the prevalence and prognostic value of late gadolinium enhancement (LGE), as assessed by cardiovascular magnetic resonance (CMR) imaging, in patients with aortic stenosis. METHODS AND RESULTS:A systematic search of PubMed and EMBASE was performed, and observational cohort studies that analysed the prevalence of LGE and its relation to clinical outcomes in patients with aortic stenosis were included. Odds ratios were used to measure an effect of the presence of LGE on both all-cause and cardiovascular mortality. Nineteen studies were retrieved, accounting for 2032 patients (mean age 69.8 years, mean follow-up 2.8 years). We found that LGE is highly prevalent in aortic stenosis, affecting half of all patients (49.6%), with a non-infarct pattern being the most frequent type (63.6%). The estimated extent of focal fibrosis, expressed in % of LV mass, was equal to 3.83 (95% CI [2.14, 5.52], p < 0.0001). The meta-analysis showed that the presence of LGE was associated with increased all-cause (pooled OR [95% CI] = 3.26 [1.72, 6.18], p = 0.0003) and cardiovascular mortality (pooled OR [95% CI] = 2.89 [1.90, 4.38], p < 0.0001). CONCLUSIONS:LGE by CMR is highly prevalent in aortic stenosis patients and exhibits a substantial value in all-cause and cardiovascular mortality prediction. These results suggest a potential role of LGE in aortic stenosis patient risk stratification. KEY POINTS:• Up to the half of aortic stenosis patients are affected by myocardial focal fibrosis. • Sixty-four percent of focal fibrosis detected by LGE-CMR is non-infarct type. • The presence of focal fibrosis triples all-cause and cardiovascular mortality.
journal_name
Eur Radioljournal_title
European radiologyauthors
Balciunaite G,Skorniakov V,Rimkus A,Zaremba T,Palionis D,Valeviciene N,Aidietis A,Serpytis P,Rucinskas K,Sogaard P,Glaveckaite Sdoi
10.1007/s00330-019-06386-3subject
Has Abstractpub_date
2020-01-01 00:00:00pages
640-651issue
1eissn
0938-7994issn
1432-1084pii
10.1007/s00330-019-06386-3journal_volume
30pub_type
杂志文章,meta分析abstract:PURPOSE:Late gadolinium enhancement cardiac MR (LGE-CMR) and extracellular volume fraction (ECV-CMR) are widely used to evaluate macroscopic and microscopic myocardial fibrosis. Macrocyclic contrast media are increasingly used off-label for myocardial scar assessment, given the superior safety profile of these agents. ...
journal_title:European radiology
pub_type: 杂志文章
doi:10.1007/s00330-018-5956-3
更新日期:2019-08-01 00:00:00
abstract:OBJECTIVES:We aimed to assess the diagnostic performance of a combined protocol with coronary computed tomography angiography (CCTA) and stress CT perfusion imaging (CTP) in heart transplant patients for comprehensive morphological and functional imaging. METHODS:In this prospective study, 13 patients undergoing routi...
journal_title:European radiology
pub_type: 杂志文章
doi:10.1007/s00330-018-5436-9
更新日期:2018-10-01 00:00:00
abstract:OBJECTIVES:Complications following colorectal cancer resection are common. The degree of aortic calcification (AC) on CT has been proposed as a predictor of complications, particularly anastomotic leak. This study assessed the relationship between AC and complications in patients undergoing colorectal cancer resection....
journal_title:European radiology
pub_type: 杂志文章
doi:10.1007/s00330-020-07189-7
更新日期:2020-11-17 00:00:00
abstract::The purpose of this study was to assess diaphragmatic length and shortening during the breathing cycle in healthy volunteers and patients with a lung tumor using dynamic MRI (dMRI). In 15 healthy volunteers and 28 patients with a solitary lung tumor, diaphragmatic motion and length were measured during the breathing c...
journal_title:European radiology
pub_type: 临床试验,杂志文章
doi:10.1007/s00330-004-2336-y
更新日期:2004-08-01 00:00:00
abstract::Earlier studies have shown that single-energy quantitative computed tomography (SEQCT) is a reliable method for bone mineral density (BMD) measurements in thoracic and lumbar vertebrae. Moreover, SEQCT has proved to be a useful parameter in the selection of appropriate implants in cervical spondylodesis. The aim of th...
journal_title:European radiology
pub_type: 杂志文章
doi:10.1007/s003300050312
更新日期:1997-01-01 00:00:00
abstract:OBJECTIVES:To determine the residual lipid fraction in fractured vertebrae by (1)H MR spectroscopy (MRS) and its confounding effect on differentiating benign from metastatic compression fractures of the spine using apparent diffusion coefficient (ADC) obtained by diffusion-weighted read-out-segmented echo-planar imagin...
journal_title:European radiology
pub_type: 杂志文章
doi:10.1007/s00330-012-2620-1
更新日期:2013-02-01 00:00:00
abstract::CT-guided procedures remain an important tool for diagnosis and tissue acquisition for primary diagnosis and molecular/tissue correlation. New imaging devices such as MDCT and PET/CT will improve diagnosis but percutaneous procedures will be needed to confirm and support new molecular and DNA treatments. Coagulopathic...
journal_title:European radiology
pub_type: 杂志文章,评审
doi:10.1007/s10406-005-0130-9
更新日期:2005-11-01 00:00:00
abstract::A method for cardio-thoracic multislice spiral CT imaging with ECG gating for suppression of heart pulsation artifacts is introduced. The proposed technique offers extended volume coverage compared with standard ECG-gated spiral scan and reconstruction approaches for cardiac applications: Thin-slice data of the entire...
journal_title:European radiology
pub_type: 杂志文章
doi:10.1007/s00330-002-1388-0
更新日期:2002-06-01 00:00:00
abstract:OBJECTIVES:Coronary artery volume indexed to left myocardial mass (CAVi), derived from coronary computed tomography angiography (CCTA), has been proposed as an indicator of diffuse atherosclerosis. We investigated the association of CAVi with quantitative flow parameters and its ability to predict ischemia as derived f...
journal_title:European radiology
pub_type: 杂志文章
doi:10.1007/s00330-020-07586-y
更新日期:2021-01-16 00:00:00
abstract::We report the case of a 1.5-year-old girl with transient protein-losing gastropathy with hypertrophic gastric folds (PLGH). The diagnosis of PLGH was made by abdominal ultrasound (US) and not by an upper gastrointestinal (UGI) study as reported in many previous publications. Real-time compound ultrasound imaging showe...
journal_title:European radiology
pub_type: 杂志文章
doi:10.1007/s00330-003-2071-9
更新日期:2003-12-01 00:00:00
abstract::Aim of this study was to develop a time-efficient sequence protocol for a 1.0 T dedicated MR system to be used for whole-organ scoring of osteoarthritis (OA). Thirty-four knees were examined using a protocol that included fat suppressed fast spin echo proton density weighted sequences (PDFS) in three planes plus a cor...
journal_title:European radiology
pub_type: 杂志文章,多中心研究
doi:10.1007/s00330-004-2608-6
更新日期:2005-05-01 00:00:00
abstract::The RETAIN project (Radiological Examinations Transfer on an ATM Integrated Network) has aimed at testing videoconferencing and DICOM image transfers to get advice about difficult radiological cases over an asynchronous transfer mode (ATM)-based network, which affords a more comfortable interface than narrow-band netw...
journal_title:European radiology
pub_type: 杂志文章
doi:10.1007/s003300050029
更新日期:2000-01-01 00:00:00
abstract:OBJECTIVES:To evaluate the feasibility and reproducibility of superb microvascular imaging (SMI) of the neonatal brain and to describe normal imaging features. METHODS:We performed transcranial ultrasound with SMI in 19 healthy term-born neonates. SMI was done according to a structured examination protocol, using two ...
journal_title:European radiology
pub_type: 杂志文章
doi:10.1007/s00330-018-5743-1
更新日期:2019-04-01 00:00:00
abstract::Management of trauma patients relies on a simple but obvious concept: Time is life! This is a challenge to the emergency radiologist in his evaluation of the radiological admission survey of severe trauma patients, since the latter need a quick and thorough survey of craniocerebral, cervical, thoracic, abdominal, and ...
journal_title:European radiology
pub_type: 杂志文章
doi:10.1007/s00330-002-1385-3
更新日期:2002-05-01 00:00:00
abstract:OBJECTIVES:Clinical applications of susceptibility-weighted imaging (SWI) are increasing steadily. The aim of this study is to investigate the appearance of cerebral veins on SWI, which is very sensitive to the deoxyhaemoglobin level in vessels, in pulmonary embolism (PE). METHODS:The cranial SWI images of 19 patients...
journal_title:European radiology
pub_type: 杂志文章
doi:10.1007/s00330-016-4606-x
更新日期:2017-07-01 00:00:00
abstract:OBJECTIVES:To compare [(18)F]FDG PET/MRI with PET/CT for the assessment of bone lesions in oncologic patients. METHODS:This prospective study included 67 patients with solid tumours scheduled for PET/CT with [(18)F]FDG who also underwent a whole-body PET/MRI scan. The datasets (PET/CT, PET/MRI) were rated by two reade...
journal_title:European radiology
pub_type: 杂志文章
doi:10.1007/s00330-014-3229-3
更新日期:2014-08-01 00:00:00
abstract::Acute cerebral stroke remains a major cause of death among adults and the emergence of new therapies has created a need for early and rapid imaging at a time when conventional CT is either normal or demonstrates subtle abnormalities that are easy to misinterpret. Perfusion CT uses the temporal changes in cerebral and ...
journal_title:European radiology
pub_type: 杂志文章,评审
doi:10.1007/s00330-003-2104-4
更新日期:2003-12-01 00:00:00
abstract::Eight interhemispheric lipomas (five tubulonodular lipomas and three curvilinear lipomas) were examined by magnetic resonance imaging (MRI). The purpose was to further investigate the relationship between the morphology of the different subtypes and the clinical presentation. The imaging findings were reviewed in ligh...
journal_title:European radiology
pub_type: 杂志文章
doi:10.1007/BF00240701
更新日期:1996-01-01 00:00:00
abstract:OBJECTIVE:Evaluate the performance of a robotic system for CT-guided lung biopsy in comparison to the conventional manual technique. MATERIALS AND METHODS:One hundred patients referred for CT-guided lung biopsy were randomly assigned to group A (robot-assisted procedure) or group B (conventional procedure). Size, dist...
journal_title:European radiology
pub_type: 杂志文章,随机对照试验
doi:10.1007/s00330-014-3508-z
更新日期:2015-05-01 00:00:00
abstract::The potential for low dose computed tomography (LDCT) to act as an effective tool in screening for lung cancer is currently the subject of several randomised control trials. It has recently been given prominence by interim results released by the North American National Lung Screening Trial (NLST). Several other trial...
journal_title:European radiology
pub_type: 杂志文章,评审
doi:10.1007/s00330-011-2219-y
更新日期:2011-12-01 00:00:00
abstract:OBJECTIVE:To compare the sensitivity, specificity, and diagnostic accuracy of fat-only datasets reconstructed using a two-point Dixon technique, with corresponding opposed-phase (OP) and in-phase (IP) datasets for characterization of adrenal lesions at 3 Tesla (T). METHODS:Fifty-nine patients (21 male, 38 female) with...
journal_title:European radiology
pub_type: 杂志文章
doi:10.1007/s00330-011-2244-x
更新日期:2012-01-01 00:00:00
abstract::Cardiac angiosarcoma is a rare tumour entity with a poor prognosis. Early detection is difficult but important for the further course of the disease. We report on a young patient with a tumour of unknown origin and dignity of the right atrium. Magnetic resonance imaging, CT and echocardiography were sufficient in loca...
journal_title:European radiology
pub_type: 杂志文章
doi:10.1007/s00330-002-1478-z
更新日期:2002-12-01 00:00:00
abstract:OBJECTIVE:To identify which breast lesion descriptors in the ACR BI-RADS® MRI lexicon are most strongly associated with the diagnosis of breast cancer when performing breast MR imaging at 3 T. METHODS:150 patients underwent breast MR imaging at 3 T. Lesion size, morphology and enhancement kinetics were assessed accord...
journal_title:European radiology
pub_type: 杂志文章
doi:10.1007/s00330-011-2256-6
更新日期:2012-02-01 00:00:00
abstract:OBJECTIVE:To develop recommendations that can be used as guidance for standardized approach regarding indications, patient preparation, sequences acquisition, interpretation and reporting of magnetic resonance imaging (MRI) for diagnosis and grading of pelvic floor dysfunction (PFD). METHODS:The technique included cri...
journal_title:European radiology
pub_type: 共识发展会议,杂志文章
doi:10.1007/s00330-016-4471-7
更新日期:2017-05-01 00:00:00
abstract:OBJECTIVES:To explore the role of dynamic contrast-enhanced (DCE) magnetic resonance imaging (MRI), using semiquantitative and quantitative parameters, and diffusion-weighted (DW) MRI in differentiating benign from malignant small, non-palpable solid testicular tumours. METHODS:We calculated the following DCE-MRI para...
journal_title:European radiology
pub_type: 杂志文章
doi:10.1007/s00330-017-5013-7
更新日期:2018-02-01 00:00:00
abstract::The purpose of this study was to use cine-MRI during continuous respiration to measure the respiratory lumenal diameter change in the pharynx and at an upper tracheal level. Fifteen non-smokers and 23 chronic obstructive pulmonary disease (COPD) patients with smoking history (median 50 pack-years) were included. Cine-...
journal_title:European radiology
pub_type: 杂志文章
doi:10.1007/s00330-004-2461-7
更新日期:2004-12-01 00:00:00
abstract::To prove the usefulness of a simple laser marker system (LMS) in target definition as well as examination procedure for CT-guided interventions, 130 cases of diagnostic biopsies and lumbal sympathectomies were compared. In 75 cases LMS and in 55 cases a simple crossgrid was used. Taking advantage of the LMS, the param...
journal_title:European radiology
pub_type: 杂志文章
doi:10.1007/s003300051054
更新日期:2000-01-01 00:00:00
abstract:OBJECTIVES:To assess if the administration of gadoxetate disodium (Gd-EOB-DTPA) significantly affects hepatic magnetic resonance elastography (MRE) measurements in the delayed hepatobiliary phase (DHBP). METHODS:A total of 47 patients (15 females, 32 males; age range 23-78 years, mean 54.28 years) were assigned to sta...
journal_title:European radiology
pub_type: 杂志文章
doi:10.1007/s00330-018-5616-7
更新日期:2019-02-01 00:00:00
abstract:AIM:To describe the effect of hepatobiliary-specific MR imaging contrast agent (HBCA) administration on the signal intensity of peritoneal and pleural fluid effusions on T1-weighted MR images. MATERIALS AND METHODS:From October 2015 to May 2016 139 patients (mean 60±10 years old, 69 % males) with peritoneal or pleural...
journal_title:European radiology
pub_type: 杂志文章
doi:10.1007/s00330-017-5261-6
更新日期:2018-07-01 00:00:00
abstract::Cystic angiomatosis is a rare disorder with a poor prognosis. We describe a case of a 33-year-old woman who presented with longstanding bone pain, hemolytic anemia, and an enlarged spleen. Radiologically, multiple osseous lesions with a mixed pattern of lytic and sclerotic areas were seen within the shoulders, spine, ...
journal_title:European radiology
pub_type: 杂志文章
doi:10.1007/s00330-002-1805-4
更新日期:2003-12-01 00:00:00