Abstract:
OBJECTIVES:To determine the residual lipid fraction in fractured vertebrae by (1)H MR spectroscopy (MRS) and its confounding effect on differentiating benign from metastatic compression fractures of the spine using apparent diffusion coefficient (ADC) obtained by diffusion-weighted read-out-segmented echo-planar imaging. METHODS:Fifty-two patients presenting with back pain and/or vertebral compression fractures related to different degrees of acute trauma, osteoporosis or clinically known metastatic disease underwent imaging at 1.5 T using (a) single-voxel MRS for water and lipid compositions over the fractured vertebral marrow, and (b) DWI at b = 0 and 650 s/mm(2) to compute the ADC values. RESULTS:In 46 fractured vertebrae, the amount of lipid displaced was variable. In low-impact trauma, lipid was either displaced partially (ADC of 1.60 ± 0.20 × 10(-3) mm(2)/s) or almost totally with a higher ADC (2.20 ± 0.27 × 10(-3) mm(2)/s). In acute high-impact trauma, the lipid fraction was negligible, yet an intermediate ADC was observed. In tumour infiltration, ADC was also intermediate (1.22 ± 0.14 × 10(-3) mm(2)/s) despite a negligible lipid fraction. The ROC curve yielded a diagnostic accuracy of 0.944. CONCLUSION:ADC-MRS analysis provides knowledge of the residual lipid fraction in fractured vertebrae that could aid in the differentiation between benign and metastatic vertebral fractures in low-impact trauma.
journal_name
Eur Radioljournal_title
European radiologyauthors
Rumpel H,Chong Y,Porter DA,Chan LLdoi
10.1007/s00330-012-2620-1subject
Has Abstractpub_date
2013-02-01 00:00:00pages
541-50issue
2eissn
0938-7994issn
1432-1084journal_volume
23pub_type
杂志文章abstract:OBJECTIVES:To assess the inhibitory effect of gadoxetate disodium on the transporter system using indocyanine green (ICG). MATERIALS AND METHODS:Groups of six female B6 Albino mice were injected with the test agent (0.62 mmol/kg gadoxetate disodium) or phosphate-buffered saline (control) 10 min before injection of ICG...
journal_title:European radiology
pub_type: 杂志文章
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abstract::Renal cell carcinoma in a horseshoe kidney is an unusual entity. To our knowledge, only 123 cases have been published to date. We report the first bilateral case of two clear-cell carcinomas in an asymmetrically fused kidney. Optimum preservation of renal function after radical tumor removal requires accurate preopera...
journal_title:European radiology
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pub_type: 杂志文章,随机对照试验
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更新日期:2019-06-01 00:00:00