Rapid isolation and identification of minor natural products by LC-MS, LC-SPE-NMR and ECD: isoflavanones, biflavanones and bisdihydrocoumarins from Ormocarpum kirkii.

abstract：:20(S)-protopanaxadiol (PPD(S)) and 20(R)-protopanaxadiol (PPD(R)), the main metabolites of ginsenosides Rg3(S) and Rg3(R) in black ginseng, are potential candidates for anti-cancer therapy due to their pharmacological activities such as anti-tumor properties. In the present study, we report the preparation of PPD(S, R...

journal_title：Phytochemistry

authors： Liu L,Zhu XM,Wang QJ,Zhang DL,Fang ZM,Wang CY,Wang Z,Sun BS,Wu H,Sung CK

更新日期：2010-09-01 00:00:00

abstract：:Three undescribed isoflavones, derriscandenon A, B, and C, together with seven known isoflavones were isolated and structurally characterized during a study of the chemical constituents in the leaves of Derris scandens (Roxb.) Benth (Leguminosae, Fabaceae) collected in Bangladesh. The inhibitory activity of the compou...

journal_title：Phytochemistry

authors： Ito C,Matsui T,Miyabe K,Hasan CM,Rashid MA,Tokuda H,Itoigawa M

更新日期：2020-07-01 00:00:00

abstract：:Withania somnifera, known in India as Asghawhanda, is used traditionally to treat many medical problems including diabetes and has demonstrated therapeutic activity in various animal models as well as in diabetic patients. While much of W. somnifera's therapeutic activity is attributed to withanolides, their role in t...

journal_title：Phytochemistry

authors： Gorelick J,Rosenberg R,Smotrich A,Hanuš L,Bernstein N

更新日期：2015-08-01 00:00:00

abstract：:From the pro-inflammatory active extract of Euphorbia peplus, a new diterpene polyester (1) based on the jatrophane skeleton was isolated together with the known compounds 2-5. The irritant activities of some jatrophane diterpenes (2, 3 and 6-9) were also investigated: only compound 2 was found to exert a weak pro-inf...

journal_title：Phytochemistry

authors： Hohmann J,Vasas A,Günther G,Dombi G,Blazsó G,Falkay G,Máthé I,Jerkovich G

更新日期：1999-07-01 00:00:00

abstract：:Coumarins exhibit many biological activities and are the main specialised metabolites of Peucedanum praeruptorum Dunn, an important plant used in traditional Chinese medicine. In preliminary studies, we cloned several genes involved in coumarin biosynthesis in P. praeruptorum, such as 4-coumarate: CoA ligase (4CL), p-...

journal_title：Phytochemistry

authors： Sui Z,Luo J,Yao R,Huang C,Zhao Y,Kong L

更新日期：2019-02-01 00:00:00

abstract：:From the water-soluble part of an extract of Aragoa cundinamarcensis were isolated seven iridoid glucosides, namely aucubin, catalpol, rehmannioside D, globularin, gardoside methyl ester, epiloganin and mussaenoside. The main glycoside isolated, however, was a new caffeoyl phenylethanoid triglycoside, named aragoside,...

journal_title：Phytochemistry

authors： Rønsted N,Bello MA,Jensen SR

更新日期：2003-09-01 00:00:00

abstract：:The biosynthetic origin of 9-phenylphenalenones and the sequence according to which their oxygen functionalities are introduced were studied using nuclear magnetic resonance (NMR) spectroscopy and high-resolution electrospray ionization mass spectrometry (HRESIMS). (13)C-labelled precursors were administered to root c...

journal_title：Phytochemistry

authors： Munde T,Maddula RK,Svatos A,Schneider B

更新日期：2011-01-01 00:00:00

abstract：:Seven neo-clerodanes (teupolins VI-XII) and eleven known compounds were isolated and characterized from leaf extracts of Teucrium polium L., a medicinal plant used in traditional and herbal medicine for its hypolipidemic, hypoglycemic, antioxidant and antiproliferative properties. The structures of these compounds wer...

journal_title：Phytochemistry

authors： Fiorentino A,D'Abrosca B,Pacifico S,Scognamiglio M,D'Angelo G,Gallicchio M,Chambery A,Monaco P

更新日期：2011-11-01 00:00:00

abstract：:Five new oleanane-type saponins, polygalasaponins XLII-XLVI, along with two known saponins were isolated from the roots of Polygala glomerata Lour. The structures of polygalasaponins XLII-XLVI were elucidated as 3-O-beta-D-glucopyranosyl presenegenin 28-O-beta-D-xylopyranosyl-(1-->4)-alpha-L-rhamnopyranosyl- (1-->2)-{...

journal_title：Phytochemistry

authors： Zhang D,Miyase T,Kuroyanagi M,Umehara K,Noguchi H

更新日期：1998-02-01 00:00:00

abstract：:Lychnophora ericoides is a Brazilian medicinal plant used in folk medicine as an anti-inflammatory and analgesic agent. The essential oils from leaves of two populations with and without scent, collected at 2-month intervals during an 1-year period, were analysed by GC-MS. The results were submitted to principal compo...

journal_title：Phytochemistry

authors： Curado MA,Oliveira CB,Jesus JG,Santos SC,Seraphin JC,Ferri PH

更新日期：2006-11-01 00:00:00

abstract：:The A-type proanthocyanidin, epigallocatechin-(2beta-->7,4beta-->8)-epicatechin, together with the known epicatechin, luteolin 3'beta-D-glucopyranoside, chrysoeriol 7beta-D-glucopyranoside and 2-methylpentan-2,4-diol, were isolated from leaves of Dioclea lasiophilla. The structures were established on the basis of the...

journal_title：Phytochemistry

authors： Barreiros AL,David JP,de Queiroz LP,David JM

更新日期：2000-12-01 00:00:00

abstract：:Eight ring C-seco and ring-intact limonoids, and 25 known limonoids were isolated from the fruits of Melia toosendan (Meliaceae). Their structures were elucidated on the basis of extensive spectroscopic evidence including HRMS, 1D and 2D NMR spectroscopic data. A total of 29 isolated limonoids was evaluated for NF-κB ...

journal_title：Phytochemistry

authors： Zhu GY,Bai LP,Liu L,Jiang ZH

更新日期：2014-11-01 00:00:00

abstract：:Three alkaloids, neoharringtonine, homoneoharringtonine and 3'S-hydroxyneoharringtonine, were isolated from the leaves and stems of Cephalotaxus harringtonia var. drupacea. Their structures were established by spectroscopic methods, including two-dimensional NMR and CD spectra, and their antileukaemic activity was eva...

journal_title：Phytochemistry

authors： Takano I,Yasuda I,Nishijima M,Yanagi Y,Takeya K,Itokawa H

更新日期：1997-02-01 00:00:00

abstract：:Two new flavanoids, 5,7-dimethoxy-3',4'-methylenedioxyflavanone and isobonducellin along with 2'-hydroxy-2,3,4',6'-tetramethoxychalcone, 5,7-dimethoxyflavone and bonducellin were isolated from the aerial parts of Caesalpinia pulcherrima. The structures of the compounds were settled mainly by interpretation of their 1D...

journal_title：Phytochemistry

authors： Srinivas KV,Koteswara Rao Y,Mahender I,Das B,Rama Krishna KV,Hara Kishore K,Murty US

更新日期：2003-08-01 00:00:00

abstract：:Valerophenone synthase (VPS) is a polyketide synthase that catalyzes the formation of the phloroglucinol derivatives in the synthesis of the bitter acids in hop (Humulus lupulus). The reaction uses isovaleryl-CoA or isobutyryl-CoA, but otherwise it is identical to that of the chalcone synthase in flavonoid biosynthesi...

journal_title：Phytochemistry

authors： Zuurbier KW,Leser J,Berger T,Hofte AJ,Schröder G,Verpoorte R,Schröder J

更新日期：1998-12-01 00:00:00

abstract：:The structure of cephalaria saponin B, isolated from Cephalaria transsylvanica was elucidated as 3-O-([beta-D-xylopyranosyl(1-->4)-alpha-L-rhamnopyranosyl(1-->2)-beta-D- xylopyranosyl]-[28-O-beta-D-glucopyranosyl])-3beta,23-dihydroxy-12(13)-oleanene-28-oic acid. ...

journal_title：Phytochemistry

authors： Alankuş-Calişkan O,Anil H

更新日期：1995-04-01 00:00:00

abstract：:Three phenylpropanoid glycosides named ningposides A (3-O-acetyl-2-O-feruloyl-alpha-L-rhamnopyranose), B (4-O-acetyl-2-O-feruloyl-alpha-L-rhamnopyranose) and C (3-O-acetyl-2-O-p-hydroxycinnamoyl-alpha-L-rhamnopyranose) along with the known compounds sibirioside A, cistanoside D, angoroside C, acteoside, decaffeoylacte...

journal_title：Phytochemistry

authors： Li YM,Jiang SH,Gao WY,Zhu DY

更新日期：2000-08-01 00:00:00

abstract：:Cytochrome P450-dependent monooxygenases (P450s) belonging to the CYP93E subfamily catalyze the C-24 oxidation of the triterpene backbone during the biosynthesis of triterpenoid saponins, which are bioactive plant natural products. In our attempts to produce plant triterpenoids in the yeast Saccharomyces cerevisiae, w...

journal_title：Phytochemistry

authors： Moses T,Thevelein JM,Goossens A,Pollier J

更新日期：2014-12-01 00:00:00

abstract：:Bioassay-guided fractionation of an extract prepared from the fruits of Cordia sebestena led to the isolation of sebestenoids A-D (1-4). Their structures were elucidated on the basis of extensive NMR experiments and mass spectroscopic measurements. Compounds 1-4 exhibited moderate inhibition of the aspartic protease B...

journal_title：Phytochemistry

authors： Dai J,Sorribas A,Yoshida WY,Williams PG

更新日期：2010-12-01 00:00:00

abstract：:Phenylpropanoid glycosides, 1'-O-benzyl-alpha-L-rhamnopyranosyl-(1''-->6')-beta-D-glucopyranoside (1) and alpha-L-xylopyranosyl-(4''-->2')-(3-O-beta-D-glucopyranosyl)-1'-O-E-caffeoyl-beta-D-glucopyranoside (2), together with the known derivatives, 1,6-di-O-caffeoyl-beta-D-glucopyranoside (3), 1-O-(E)-caffeoyl-beta-D-g...

journal_title：Phytochemistry

authors： Hamerski L,Bomm MD,Silva DH,Young MC,Furlan M,Eberlin MN,Castro-Gamboa I,Cavalheiro AJ,da Silva Bolzani V

更新日期：2005-08-01 00:00:00

abstract：:The effects of UVB radiation on plant growth rate, gene expression and flavonoid content in wild-type, and in transgenic and mutant F3'H deficient Petunia lines have been studied for the first time. In wild-type Petunia, UVB induced an increase in total levels of flavonols and this was due to an up-regulation of sever...

journal_title：Phytochemistry

authors： Ryan KG,Swinny EE,Markham KR,Winefield C

更新日期：2002-01-01 00:00:00

abstract：:Six new steroidal saponins have been isolated from the fresh bulbs of Camassia cusickii. Their structures were determined by spectroscopic analysis and some chemical transformations to be (25R)-5 alpha-spirostan-3 beta,6 alpha-diol (chlorogenin) 6-O-beta-D-glucopyranoside, chlorogenin 6-O-beta-D-glucopyranosyl-(1----2...

journal_title：Phytochemistry

authors： Mimaki Y,Sashida Y,Kawashima K

更新日期：1991-01-01 00:00:00

abstract：:Glucosinolates are sulphur-containing glycosides found in brassicaceous plants that can be hydrolysed enzymatically by plant myrosinase or non-enzymatically to form primarily isothiocyanates and/or simple nitriles. From a human health perspective, isothiocyanates are quite important because they are major inducers of ...

journal_title：Phytochemistry

authors： Williams DJ,Critchley C,Pun S,Chaliha M,O'Hare TJ

更新日期：2009-07-01 00:00:00

abstract：:Microbial transformation of (+/-)-eudesmin by Aspergillus niger was investigated. Enantioselective accumulation of (--)-pinoresinol was shown through O-demethylation of (+/-)-eudesmin. This fungus O- demethylated both enantiomers of eudesmin, but the conversion rates for each enantiomer were clearly different. ...

journal_title：Phytochemistry

authors： Kasahara H,Miyazawa M,Kameoka H

更新日期：1997-04-01 00:00:00

abstract：:Five novel polyphenols have been isolated from the air-dried herb of Cistus salvifolius; they were characterized as epigallocatechin-3-O-(4-hydroxybenzoate), epigallocatechin-(4 beta-->8)-epigallocatechin, epigallocatechin-3-O- gallate-(4 beta-->8)-epigallocatechin, epigallocatechin-(4 beta-->6)-epigallocatechin-3-O-g...

journal_title：Phytochemistry

authors： Danne A,Petereit F,Nahrstedt A

更新日期：1994-09-01 00:00:00

abstract：:Two new oleanene glycosides (1-2) possessing hederagenin as the aglycone were isolated from the methanolic extract of the aerial parts of Caltha polypetala together with four known glycosides. The saccharide portion linked to C-3 of the aglycone is made up of alpha-L-arabinopyranose, alpha-L-rhamnopyranose and galacto...

journal_title：Phytochemistry

authors： Baykal T,Bedir E,Calis I,Aquino R,Piacente S,Pizza C

更新日期：1999-08-01 00:00:00

abstract：:The Madagascar periwinkle produces a large palette of Monoterpenoid Indole Alkaloids (MIAs), a class of complex alkaloids including some of the most valuable plant natural products with precious therapeutical values. Evolutionary pressure on one of the hotspots of biodiversity has obviously turned this endemic Malagas...

journal_title：Phytochemistry

authors： Dugé de Bernonville T,Clastre M,Besseau S,Oudin A,Burlat V,Glévarec G,Lanoue A,Papon N,Giglioli-Guivarc'h N,St-Pierre B,Courdavault V

更新日期：2015-05-01 00:00:00

abstract：:Benzoxazinoids are secondary metabolites of grasses that function as natural pesticides. While many steps of DIMBOA biosynthesis have been elucidated, the mechanism of the introduction of OCH(3)-group at the C-7 position was unknown. Inhibitor experiments in Triticum aestivum and Zea mays suggest that a 2-oxoglutarate...

journal_title：Phytochemistry

authors： Frey M,Huber K,Park WJ,Sicker D,Lindberg P,Meeley RB,Simmons CR,Yalpani N,Gierl A

更新日期：2003-02-01 00:00:00

abstract：:Four cycloartane-type saponins, kahiricosides II-V (1-4), were isolated from the aerial parts of Astragalus kahiricus of Egyptian origin. Their structures were established as 9beta,19-cyclolanost-24E-ene-3beta,6alpha,16beta,27-tetraol-3-O-beta-D-glucopyranoside, 9beta,19-cyclolanost-24E-ene-3beta,6alpha,16beta,27-tetr...

journal_title：Phytochemistry

authors： Radwan MM,El-Sebakhy NA,Asaad AM,Toaima SM,Kingston DG

更新日期：2004-11-01 00:00:00

abstract：:From the MeOH extract of the leaves of W. japonica, seven phenylpropanoid gentiobiosides (1-7) were isolated along with eight known phenylpropanoids (8-15). Structures of 1-7 were determined based on spectroscopic data and chemical evidence. The activity of compounds 1-15 to scavenge superoxide anion radicals was inve...

journal_title：Phytochemistry

authors： Hosoya T,Yun YS,Kunugi A

更新日期：2008-02-01 00:00:00