Enhanced bone tissue regeneration of a biomimetic cellular scaffold with co-cultured MSCs-derived osteogenic and angiogenic cells.

abstract：OBJECTIVES:Small aromatic compounds like flavonoids can intercalate with DNA molecules bringing about conformational changes leading to reduced replication and transcription. Here, we have examined one dietary flavonoid, quercetin (found in many fruit and vegetables), for possible anti-cancer effects, on HeLa cells ori...

journal_title：Cell proliferation

authors： Bishayee K,Ghosh S,Mukherjee A,Sadhukhan R,Mondal J,Khuda-Bukhsh AR

更新日期：2013-04-01 00:00:00

abstract：:Estimates of the clonogen content (number of microcolony-forming cells) of murine intestinal crypts using microcolony assays show an apparent dependence on the radiation dose used in the assay of clonogen content. Crypt radiation survival curves often show increased curvature beyond that expected on the basis of the c...

journal_title：Cell proliferation

authors： Roberts SA,Hendry JH,Potten CS

更新日期：2003-08-01 00:00:00

abstract：OBJECTIVES:High mobility group protein2 (HMGA2) and epithelial-to-mesenchymal transition are both related to progress of bladder cancer, however, the relationship between HMGA2, E-cadherin and vimentin in bladder cancer is not yet known. Thus, this study has examined expression of HMGA2, E-cadherin and vimentin in blad...

journal_title：Cell proliferation

authors： Ding X,Wang Y,Ma X,Guo H,Yan X,Chi Q,Li J,Hou Y,Wang C

更新日期：2014-04-01 00:00:00

abstract：OBJECTIVES:The aim of the current study was to investigate whether nicotine treatment would induce the proliferation of isolated rat primary pancreatic acinar cells in culture by activating mitogen-activated protein kinase (MAPK) signalling and exocrine secretion. MATERIALS AND METHODS:A nicotine dose- and time-respon...

journal_title：Cell proliferation

authors： Chowdhury P,Bose C,Udupa KB

更新日期：2007-02-01 00:00:00

abstract：OBJECTIVES:This study investigated effects of reduced serum condition and vascular endothelial growth factor (VEGF) on angiogenic potential of adipose stromal cells (ASCs) in vitro. MATERIALS AND METHODS:Adipose stromal cells were cultured in three different types of medium: (i) F12/DMEM (FD) supplemented with 10% FBS...

journal_title：Cell proliferation

authors： Chua KH,Raduan F,Wan Safwani WK,Manzor NF,Pingguan-Murphy B,Sathapan S

更新日期：2013-06-01 00:00:00

abstract：:Studies on growth regulation in vitro to a large extent rely on comparison of growth curves. However, these do not discriminate between the relative contributions of the mitotic rate and the apoptotic rate to the net growth rate. In the present study, differential effects of 17beta-oestradiol (E2, 10(-8) M) and/or tam...

journal_title：Cell proliferation

authors： Budtz PE

更新日期：1999-10-01 00:00:00

abstract：:Laminin-2 (LN-2, alpha2beta1gamma1) is a basement membrane-associated laminin isoform usually considered in the context of muscle and nerve tissues. To test the hypothesis that LN-2 can additionally modulate epithelial cell biology, an analysis of the role of LN-2 in cell adhesion, activation of signalling intermediat...

journal_title：Cell proliferation

authors： Dowgiert J,Sosne G,Kurpakus-Wheater M

更新日期：2004-04-01 00:00:00

abstract：OBJECTIVES:Induced pluripotent stem cell (iPSC)-derived cardiomyocytes are a promising source of cells for regenerative heart disease therapies, but progress towards their use has been limited by their low differentiation efficiency and high cellular heterogeneity. Previous studies have demonstrated expression of adren...

journal_title：Cell proliferation

authors： Li XL,Zeng D,Chen Y,Ding L,Li WJ,Wei T,Ou DB,Yan S,Wang B,Zheng QS

更新日期：2017-02-01 00:00:00

abstract：:Several methods to synchronize cultured cells in the cell cycle are based on temporary inhibition of DNA replication. Previously it has been reported that cells synchronized this way exhibited significant growth imbalance and unscheduled expression of cyclins A and B1. We have now observed that HL-60 cells exposed to ...

journal_title：Cell proliferation

authors： Kurose A,Tanaka T,Huang X,Traganos F,Darzynkiewicz Z

更新日期：2006-06-01 00:00:00

abstract：OBJECTIVE:Serum is usually added to growth media when mammalian cells are cultured in vitro to supply the cells with growth factors, hormones, nutrients and trace elements. Defined proteins and metal ions, such as insulin, growth factors, transferrin and sodium selenite, are sometimes also included and can in some case...

journal_title：Cell proliferation

authors： Zander L,Bemark M

更新日期：2008-02-01 00:00:00

abstract：:RAIDD (RIP-associated ICH-1 homologous protein with a death domain) is an adaptor molecule that mediates the action of cysteine proteases involved in apoptosis. To study the possibility of a novel system of cell ablation mediated by RAIDD, a preadipocyte cell line (3T3L1) was stably transfected with a plasmid containi...

journal_title：Cell proliferation

authors： Felmer R,Horvat S,Clinton M,Clark AJ

更新日期：2003-02-01 00:00:00

abstract：OBJECTIVES:During human pregnancy, the endothelial cells of the uterine spiral arteries (SPA) are extensively replaced by a subtype of placental trophoblasts, endovascular extravillous trophoblasts (enEVTs), thus establishing a placental-maternal circulation. On this pathway, foetus-derived placental villi and enEVTs b...

journal_title：Cell proliferation

authors： Ma Y,Yang Q,Fan M,Zhang L,Gu Y,Jia W,Li Z,Wang F,Li YX,Wang J,Li R,Shao X,Wang YL

更新日期：2020-05-01 00:00:00

abstract：:Triple-negative breast cancer (TNBC) is one of the most aggressive subtypes of breast cancer with negativity for oestrogen receptor (ER), progesterone receptor (PR) and human epidermal growth factor receptor (HER2). Non-coding RNAs (ncRNAs) make up most of the transcriptome and are widely present in eukaryotic cells. ...

journal_title：Cell proliferation

authors： Mei J,Hao L,Wang H,Xu R,Liu Y,Zhu Y,Liu C

更新日期：2020-05-01 00:00:00

abstract：OBJECTIVES:Advanced head and neck carcinomas (HNCs) are aggressive tumours, mainly due to hypoxia and a cancer stem cell (CSC) subpopulation. The aim of this study was to simulate tumour growth and behaviour during radiotherapy of three HNC groups (governed by different growth kinetics, hypoxia levels and CSC division ...

journal_title：Cell proliferation

authors： Marcu LG,Marcu D,Filip SM

更新日期：2016-06-01 00:00:00

abstract：:During brain development, a population of uniform embryonic cells migrates and differentiates into a large number of neural phenotypes - origin of the enormous complexity of the adult nervous system. Processes of cell proliferation, differentiation and programmed death of no longer required cells, do not occur only du...

journal_title：Cell proliferation

authors： Ulrich H,Bocsi J,Glaser T,Tárnok A

更新日期：2014-02-01 00:00:00

abstract：:The human skin equivalent (HSE) is an in vitro reconstructed model that resembles skin morphologically and biochemically. The HSE is formed by overlaying a fibroblast-populated collagen matrix with a suspension of epidermal cells. Basal keratinocytes attach to the dermal equivalent via a newly formed basement membrane...

journal_title：Cell proliferation

authors： Graeter LJ,Hull BE

更新日期：1996-12-01 00:00:00

abstract：OBJECTIVES:Whole-tooth regeneration for tooth loss has long been a goal of dentistry. There is also an increasing demand to carry out pre-clinical in vitro and in vivo research methods in large animal model similar to human. The miniature pig has proven to be an alternative as a large mammal model owing to its many sim...

journal_title：Cell proliferation

authors： Wang F,Wu Z,Fan Z,Wu T,Wang J,Zhang C,Wang S

更新日期：2018-08-01 00:00:00

abstract：:We previously found that the stable overexpression of oestrogen receptor-alpha in the human endothelial cell line ECV304* inhibits its growth in vitro, and that this inhibition is possibly mediated through a down-regulation of the vasoactive agents endothelin-1 and vascular endothelial growth factor. Here we show an i...

journal_title：Cell proliferation

authors： Ali SH,O'Donnell AL,Balu D,Pohl MB,Seyler MJ,Mohamed S,Mousa S,Dandona P

更新日期：2001-08-01 00:00:00

abstract：:Hepatocellular carcinoma (HCC) is a primary liver malignancy with a high global prevalence and a dismal prognosis. Studies are urgently needed to examine the molecular pathogenesis and biological characteristics of HCC. Chromatin remodelling, an integral component of the DNA damage response, protects against DNA damag...

journal_title：Cell proliferation

authors： Hu B,Lin JZ,Yang XB,Sang XT

更新日期：2020-04-01 00:00:00

abstract：OBJECTIVES:To evaluate the effects of rRNA synthesis inhibition on cell cycle progression and cell population growth according to the RB and p53 status. MATERIAL AND METHODS:RB- and p53-proficient U2OS cells and the RB- and p53-deficient SAOS-2 cells were used, rRNA transcription hindered by actinomycin D, and cell cy...

journal_title：Cell proliferation

authors： Montanaro L,Mazzini G,Barbieri S,Vici M,Nardi-Pantoli A,Govoni M,Donati G,Treré D,Derenzini M

更新日期：2007-08-01 00:00:00

abstract：OBJECTIVE:Low levels of adiponectin (APN), a biomarker of diabetes mellitus, have been implicated in the poor outcome of intracerebral haemorrhage (ICH). Herein, we aimed to demonstrate the neuroprotective effects of a blood-brain barrier-permeable APN peptide (APNp) on ICH injury in diabetic mice and explore the under...

journal_title：Cell proliferation

authors： Wu X,Luo J,Liu H,Cui W,Guo W,Zhao L,Guo H,Bai H,Guo K,Feng D,Qu Y

更新日期：2020-02-01 00:00:00

abstract：:The association between the phosphorylation status of the retinoblastoma protein, pRb and changes in cell cycle control caused by either protein kinase C (PKC) or protein kinase A (PKA) stimulation was evaluated in human myeloblastic leukaemia ML-1 cells. TPA-induced PKC activation resulted in dephosphorylation of pRb...

journal_title：Cell proliferation

authors： Reinach PS,Li T,Lu L

更新日期：2000-08-01 00:00:00

abstract：:A model of intestinal crypt organization is suggested based on the assumption that stem cells have a finite replicative life span. The model assumes the existence in a crypt of a quiescent ('deep') stem cell and a few more actively cycling ('proximate') stem cells. Monte Carlo computer simulation of published intestin...

journal_title：Cell proliferation

authors： Lobachevsky PN,Radford IR

更新日期：2006-10-01 00:00:00

abstract：OBJECTIVES:Mesenchymal stem cells (MSCs) are frequently used for bone regeneration, however, they are limited in quantity. Moreover, their proliferation and differentiation capabilities reduce during cell culture expansion. Potential application of induced pluripotent stem cells (iPSCs) has been reported as a promising...

journal_title：Cell proliferation

authors： Bastami F,Nazeman P,Moslemi H,Rezai Rad M,Sharifi K,Khojasteh A

更新日期：2017-04-01 00:00:00

abstract：OBJECTIVES:Increasing evidences suggest that inducing mesenchymal stem cells to differentiate into osteoblasts has been as an especially important component in the prevention and therapy for degenerative bone disease. Here, we identify a novel lncRNA, linc02349, which increases significantly during osteogenic different...

journal_title：Cell proliferation

authors： Cao L,Liu W,Zhong Y,Zhang Y,Gao D,He T,Liu Y,Zou Z,Mo Y,Peng S,Shuai C

更新日期：2020-05-01 00:00:00

abstract：OBJECTIVES:The aim of this study was to develop functionalized nanofibres as a simple delivery system for growth factors (GFs) and make nanofibre cell-seeded scaffold implants a one-step intervention. MATERIALS AND METHODS:We have functionalized polycaprolactone (PCL) nanofibres with thrombocytes adherent on them. Imm...

journal_title：Cell proliferation

authors： Jakubova R,Mickova A,Buzgo M,Rampichova M,Prosecka E,Tvrdik D,Amler E

更新日期：2011-04-01 00:00:00

abstract：OBJECTIVES:This study focuses on experimental analysis and corresponding mathematical simulation of in vitro HUVECs (human umbilical vein endothelial cells) proliferation in the presence of various types of drugs. MATERIALS AND METHODS:HUVECs, once seeded in Petri dishes, were expanded to confluence. Temporal profiles...

journal_title：Cell proliferation

authors： Mancuso L,Scanu M,Pisu M,Concas A,Cao G

更新日期：2010-12-01 00:00:00

abstract：OBJECTIVES:Long non-coding RNAs have identified to involve into the tumour cell proliferation, apoptosis and metastasis. We previously found that up-regulated LncRNA-SNHG7 (SNHG7) positively correlated to the Fas apoptosis inhibitory molecule 2 (FAIM2) in lung cancer cells with unclear mechanism. METHODS:Non-small cel...

journal_title：Cell proliferation

authors： She K,Yan H,Huang J,Zhou H,He J

更新日期：2018-02-01 00:00:00

abstract：OBJECTIVES:Based on in vivo studies, low-intensity pulsed ultrasound (LIPUS) stimulation has been widely used in the clinic for advancing bone growth during healing of non-union alignment, fractures and other osseous defects. In this study, we have investigated osteogenic differentiation of adipose stem cells (ASCs) re...

journal_title：Cell proliferation

authors： Yue Y,Yang X,Wei X,Chen J,Fu N,Fu Y,Ba K,Li G,Yao Y,Liang C,Zhang J,Cai X,Wang M

更新日期：2013-06-01 00:00:00

abstract：OBJECTIVES:The main purpose of current study was to explore the effects of tetrahedral DNA nanostructures (TDNs) on neuroectodermal (NE-4C) stem cells migration and unveil the potential mechanisms. MATERIALS AND METHODS:The successfully self-assembled TDNs were also determined by dynamic light scattering (DLS). A bidi...

journal_title：Cell proliferation

authors： Ma W,Xie X,Shao X,Zhang Y,Mao C,Zhan Y,Zhao D,Liu M,Li Q,Lin Y

更新日期：2018-12-01 00:00:00