The cell re-association-based whole-tooth regeneration strategies in large animal, Sus scrofa.

abstract：:The signal transducers and activators of transcription--STAT5A and STAT5B--take part in the regulation of many essential physiopathological processes. They influence the cell cycle, apoptosis and the proliferation of different types of cell lines. The STAT5 proteins are induced in response to multiple haematopoietic c...

journal_title：Cell proliferation

authors： Baśkiewicz-Masiuk M,Masiuk M,Machaliński B

更新日期：2003-10-01 00:00:00

abstract：OBJECTIVES:miRNAs play crucial roles in human tumourigenesis. This study was performed to measure expression and function of miR-762 in breast cancer. MATERIALS AND METHODS:Expression of miR-762 in breast tissues and cell lines (SK-BR-3, DA-MB-435s, MCF-7 and MDA-MB-231, HBL-100) was measured by using real-time RT-PCR...

journal_title：Cell proliferation

authors： Li Y,Huang R,Wang L,Hao J,Zhang Q,Ling R,Yun J

更新日期：2015-12-01 00:00:00

abstract：:The R- cell line is a 3T3-like cell line originating from mouse embryos with a homozygous disruption of the type 1 insulin-like growth factor receptor (IGF-IR) genes. Although R- cells cannot grow at all in serum-free medium (SFM) supplemented by several known growth factors, either singly or in combination, they are ...

journal_title：Cell proliferation

authors： Xu SQ,Sell C,DuBois GC,Baserga R

更新日期：1997-06-01 00:00:00

abstract：:L-type voltage-gated calcium ion channels (L-VGCCs) have been demonstrated to be the mediator of several significant intracellular activities in excitable cells, such as neurons, chromaffin cells and myocytes. Recently, an increasing number of studies have investigated the function of L-VGCCs in non-excitable cells, p...

journal_title：Cell proliferation

authors： Tan YZ,Fei DD,He XN,Dai JM,Xu RC,Xu XY,Wu JJ,Li B

更新日期：2019-07-01 00:00:00

abstract：OBJECTIVES:Somatic stem cells can be obtained from a variety of adult human tissues. However, it was not clear whether human parathyroid glands, which secrete parathyroid hormones and are essential in maintaining homeostasis levels of calcium ions in the circulation, contained stem cells. We aimed to investigate the po...

journal_title：Cell proliferation

authors： Shih YR,Kuo TK,Yang AH,Lee OK,Lee CH

更新日期：2009-08-01 00:00:00

abstract：OBJECTIVES:It has been widely reported that maternal diabetes impairs oocyte quality. However, the responsible mechanisms remain to be explored. In the present study, we focused on whether SIRT3-GSK3β pathway mediates the meiotic defects in oocytes from diabetic mice. MATERIALS AND METHODS:GSK3β functions in mouse ooc...

journal_title：Cell proliferation

authors： Xin Y,Jin Y,Ge J,Huang Z,Han L,Li C,Wang D,Zhu S,Wang Q

更新日期：2021-01-01 00:00:00

abstract：:Neural stem cells (NSCs) are early precursors of neuronal and glial cells. NSCs are capable of generating identical progeny through virtually unlimited numbers of cell divisions (cell proliferation), producing daughter cells committed to differentiation. Nuclear factor kappa B (NF-kappaB) is an inducible, ubiquitous t...

journal_title：Cell proliferation

authors： Piotrowska MJ,Widera D,Kaltschmidt B,an der Heiden U,Kaltschmidt C

更新日期：2006-12-01 00:00:00

abstract：OBJECTIVE:Embryo implantation needs a reciprocal interaction between competent embryo and receptive endometrium. Adenosine triphosphate (ATP) produced by stressed or injured cells acts as an important signalling molecule. This study aims to investigate whether adenosine triphosphate (ATP) plays an important role in the...

journal_title：Cell proliferation

authors： Gu XW,Yang Y,Li T,Chen ZC,Fu T,Pan JM,Ou JP,Yang ZM

更新日期：2020-02-01 00:00:00

abstract：OBJECTIVES:Creation of functional, durable vasculature remains an important goal within the field of regenerative medicine. Engineered biological vasculature has the potential to restore or improve human tissue function. We hypothesized that the pleotropic effects of insulin-like growth factor 1 (IGF1) would enhance th...

journal_title：Cell proliferation

authors： Friedrich CC,Lin Y,Krannich A,Wu Y,Vacanti JP,Neville CM

更新日期：2018-02-01 00:00:00

abstract：:Aberrant crypt foci (ACF) have been identified on the colonic mucosal surface of rodents treated with colon carcinogens and of humans after methylene-blue staining and observation under a light microscope. Several lines of evidence strongly suggest that ACF with certain morphological, histological, cell kinetics, and ...

journal_title：Cell proliferation

authors： Roncucci L,Pedroni M,Vaccina F,Benatti P,Marzona L,De Pol A

更新日期：2000-02-01 00:00:00

abstract：OBJECTIVES:Topographic cues can modulate morphology and differentiation of mesenchymal stem cells. This study aimed to determine how topographic cues of a novel bilayered poly (lactic-co-glycolic acid) (PLGA) scaffold affect osteogenic/odontogenic differentiation of dental pulp stem cells (DPSCs). METHODS:The surface ...

journal_title：Cell proliferation

authors： Du Y,Montoya C,Orrego S,Wei X,Ling J,Lelkes PI,Yang M

更新日期：2019-11-01 00:00:00

abstract：:Nerous system diseases, both central and peripheral, bring an incredible burden onto patients and enormously reduce their quality of life. Currently, there are still no effective treatments to repair nerve lesions that do not have side effects. Stem cell-based therapies, especially those using dental stem cells, bring...

journal_title：Cell proliferation

authors： Wang D,Wang Y,Tian W,Pan J

更新日期：2019-05-01 00:00:00

abstract：:Recent epidemiological studies have demonstrated a correlation between regular aspirin (acetylsalicylic acid) use and decrease risk for the development of fatal colorectal cancer. An increase in the size of the cell proliferation compartment in colorectal crypts has been correlated with an increased risk for the devel...

journal_title：Cell proliferation

authors： Barnes CJ,Lee M,Hardman WE,Cameron IL

更新日期：1995-02-01 00:00:00

abstract：OBJECTIVES:Skin-derived precursors are recognized to be a potentially autologous and accessible source of neural precursor cells for drug screening or cell-based treatments, in many neurological disorders. Thus, it is necessary to investigate appropriate methods for cryopreservation of such human skin-derived precursor...

journal_title：Cell proliferation

authors： Bakhtiari M,Mansouri K,Sadeghi Y,Mostafaie A

更新日期：2012-04-01 00:00:00

abstract：OBJECTIVES:We previously reported that Golgi phosphoprotein 3 (GOLPH3) promotes glioma progression by inhibiting EGFR endocytosis and degradation, leading to EGFR accumulation and PI3K-AKT pathway over-activation. In the current study, we examine whether GOLPH3 affects the response of glioma cells to gefitinib, an EGFR...

journal_title：Cell proliferation

authors： Wang X,Wang Z,Zhang Y,Wang Y,Zhang H,Xie S,Xie P,Yu R,Zhou X

更新日期：2019-07-01 00:00:00

abstract：OBJECTIVES:miR-21 can promote osteoblast differentiation of periodontal ligament stem cells. However, the effect of miR-21 on bone remodelling in the midpalatal suture is unclear. This study aimed to elucidate the effects of miR-21 on the midpalatal suture bone remodelling by expanding the palatal sutures. MATERIALS A...

journal_title：Cell proliferation

authors： Li M,Zhang Z,Gu X,Jin Y,Feng C,Yang S,Wei F

更新日期：2020-01-01 00:00:00

abstract：OBJECTIVES:Worldwide, lung cancer accounts for the majority of cancer-related deaths. Aberrant expression of miRNAs has increasingly been reported to be associated with tumour progression. This study aimed to explore the role of miR-301b in regulating apoptosis in lung cancer. MATERIALS AND METHODS:Expression of miR-3...

journal_title：Cell proliferation

authors： Wu D,Chen B,Cui F,He X,Wang W,Wang M

更新日期：2016-08-01 00:00:00

abstract：:Laminin-2 (LN-2, alpha2beta1gamma1) is a basement membrane-associated laminin isoform usually considered in the context of muscle and nerve tissues. To test the hypothesis that LN-2 can additionally modulate epithelial cell biology, an analysis of the role of LN-2 in cell adhesion, activation of signalling intermediat...

journal_title：Cell proliferation

authors： Dowgiert J,Sosne G,Kurpakus-Wheater M

更新日期：2004-04-01 00:00:00

abstract：:Advances in transcriptome sequencing have revealed that the genome fraction largely encodes for thousands of non-coding RNAs. Long non-coding RNAs (lncRNAs), which are a class of non-protein-coding RNAs longer than approximately 200 nucleotides in length, are emerging as key epigenetic regulators of gene expression re...

journal_title：Cell proliferation

authors： Tang L,Liang Y,Xie H,Yang X,Zheng G

更新日期：2020-01-01 00:00:00

abstract：INTRODUCTION/OBJECTIVES:The serine/threonine kinase homeodomain-interacting protein kinase 2 (HIPK2) is a co-regulator of an increasing number of transcription factors and cofactors involved in DNA damage response and development. We and others have cloned HIPK2 as an interactor of the p53 oncosuppressor, and have stud...

journal_title：Cell proliferation

authors： Iacovelli S,Ciuffini L,Lazzari C,Bracaglia G,Rinaldo C,Prodosmo A,Bartolazzi A,Sacchi A,Soddu S

更新日期：2009-06-01 00:00:00

abstract：:Triple-negative breast cancer (TNBC) is one of the most aggressive subtypes of breast cancer with negativity for oestrogen receptor (ER), progesterone receptor (PR) and human epidermal growth factor receptor (HER2). Non-coding RNAs (ncRNAs) make up most of the transcriptome and are widely present in eukaryotic cells. ...

journal_title：Cell proliferation

authors： Mei J,Hao L,Wang H,Xu R,Liu Y,Zhu Y,Liu C

更新日期：2020-05-01 00:00:00

abstract：OBJECTIVES:Articular cartilage plays a vital role in bearing and buffering. Injured cartilage and subchondral bone repair is a crucial challenge in cartilage tissue engineering due to the peculiar structure of osteochondral unit and the requirement of osteogenic/chondrogenic bi-directional differentiation. Based on the...

journal_title：Cell proliferation

authors： Shang L,Ma B,Wang F,Li J,Shen S,Li X,Liu H,Ge S

更新日期：2020-11-01 00:00:00

abstract：OBJECTIVES:To investigate the role of hierarchical micro/nanoscale topography of direct metal laser sintering (DMLS) titanium surfaces in osteogenic differentiation of bone marrow mesenchymal stem cells (BMSCs), as well as the possible underlying epigenetic mechanism. MATERIALS AND METHODS:Three groups of titanium spe...

journal_title：Cell proliferation

authors： Zheng G,Guan B,Hu P,Qi X,Wang P,Kong Y,Liu Z,Gao P,Li R,Zhang X,Wu X,Sui L

更新日期：2018-08-01 00:00:00

abstract：:A model of intestinal crypt organization is suggested based on the assumption that stem cells have a finite replicative life span. The model assumes the existence in a crypt of a quiescent ('deep') stem cell and a few more actively cycling ('proximate') stem cells. Monte Carlo computer simulation of published intestin...

journal_title：Cell proliferation

authors： Lobachevsky PN,Radford IR

更新日期：2006-10-01 00:00:00

abstract：OBJECTIVES:MicroRNAs (miRNAs) as small non-coding RNA molecules act by negatively regulating their target genes. Recent studies have shown that protein phosphatase Mg2+/Mn2+-dependent 1F (PPM1F) plays a critical role in cancer metastasis. But, the regulation mechanisms of PPM1F by miRNAs in gastric cancer (GC) remain u...

journal_title：Cell proliferation

authors： Zhang J,Jin M,Chen X,Zhang R,Huang Y,Liu H,Zhu J

更新日期：2018-08-01 00:00:00

abstract：OBJECTIVES:This study was designed to investigate the role of circ_0078767/miR-330-3p/RASSF1A in non-small-cell lung cancer (NSCLC). Bioinformatic analysis was performed to screen for the differentially expressed genes in NSCLC tissues from adjacent lung tissues. MATERIALS AND METHODS:qRT-PCR was used to detect the RN...

journal_title：Cell proliferation

authors： Chen T,Yang Z,Liu C,Wang L,Yang J,Chen L,Li W

更新日期：2019-03-01 00:00:00

abstract：OBJECTIVES:Generally, the secretory forms of FGF are known to regulate cell proliferation, differentiation and morphogenesis by binding to the extracellular domain of cell surface receptors. Intracellular FGFs (FGF11-14) are expressed principally in the nervous system. FGF13 is a microtubule-stabilizing protein that re...

journal_title：Cell proliferation

authors： Lu H,Shi X,Wu G,Zhu J,Song C,Zhang Q,Yang G

更新日期：2015-10-01 00:00:00

abstract：OBJECTIVES:Silicate bioactive glass (BG) has been widely demonstrated to stimulate both of the hard and soft tissue regeneration, in which ion products released from BG play important roles. However, the mechanism by which ion products act on cells on cells is unclear. MATERIALS AND METHODS:Human umbilical vein endoth...

journal_title：Cell proliferation

authors： Yan L,Li H,Xia W

更新日期：2020-11-01 00:00:00

abstract：OBJECTIVES:During human pregnancy, the endothelial cells of the uterine spiral arteries (SPA) are extensively replaced by a subtype of placental trophoblasts, endovascular extravillous trophoblasts (enEVTs), thus establishing a placental-maternal circulation. On this pathway, foetus-derived placental villi and enEVTs b...

journal_title：Cell proliferation

authors： Ma Y,Yang Q,Fan M,Zhang L,Gu Y,Jia W,Li Z,Wang F,Li YX,Wang J,Li R,Shao X,Wang YL

更新日期：2020-05-01 00:00:00

abstract：:Reports on the p53-related cell cycle and apoptotic responses of EBV-transformed lymphoblastoid cell lines to DNA damage have led to some confusion. This may be due to differences in the nature of the specific p53 mutations under examination, but it can also be partly attributed to methodological and analytical proble...

journal_title：Cell proliferation

authors： Gilchrist R,Lomax ME,Camplejohn RS

更新日期：1999-02-01 00:00:00