MicroRNA-21 affects mechanical force-induced midpalatal suture remodelling.

abstract：OBJECTIVE:Erythropoietin has been shown to have a protective effect in certain models of ischaemia-reperfusion, and in some cases the protection has been correlated with activation of signalling pathways known to play a role in cell survival and proliferation. We have studied whether erythropoietin would overcome direc...

journal_title：Cell proliferation

authors： Andreucci M,Fuiano G,Presta P,Lucisano G,Leone F,Fuiano L,Bisesti V,Esposito P,Russo D,Memoli B,Faga T,Michael A

更新日期：2009-08-01 00:00:00

abstract：OBJECTIVES:The transfer of melanosomes from melanocytes to neighbouring keratinocytes is critical to protect the skin from the deleterious effects of ultraviolet A (UVA) and ultraviolet B (UVB) irradiation; however, the initial factor(s) that stimulates melanosome transfer remains unclear. In this study, we investigate...

journal_title：Cell proliferation

authors： Hu QM,Yi WJ,Su MY,Jiang S,Xu SZ,Lei TC

更新日期：2017-12-01 00:00:00

abstract：OBJECTIVES:To investigate behaviour and osteogenic cytokine expression of RAW264.7 macrophages grown on TiO2 nanotube layers. MATERIALS AND METHODS:The murine macrophage cell line RAW 264.7 was cultured on TiO2 nanotubes of varying diameter; macrophage morphology was examined using scanning electron microscopy. Cell a...

journal_title：Cell proliferation

authors： Sun SJ,Yu WQ,Zhang YL,Jiang XQ,Zhang FQ

更新日期：2013-12-01 00:00:00

abstract：OBJECTIVE:This study has aimed to study different culture systems that might stimulate an increase in cell proliferation of normal and osteoarthritis chondrocytes from articular cartilage in rat model. MATERIAL AND METHODS:Three culture systems using chondrocytes embedded in alginate beads were tested: chondrocytes cu...

journal_title：Cell proliferation

authors： Gomez-Camarillo MA,Almonte-Becerril M,Vasquez Tort M,Tapia-Ramirez J,Kouri Flores JB

更新日期：2009-04-01 00:00:00

abstract：:We previously found that the stable overexpression of oestrogen receptor-alpha in the human endothelial cell line ECV304* inhibits its growth in vitro, and that this inhibition is possibly mediated through a down-regulation of the vasoactive agents endothelin-1 and vascular endothelial growth factor. Here we show an i...

journal_title：Cell proliferation

authors： Ali SH,O'Donnell AL,Balu D,Pohl MB,Seyler MJ,Mohamed S,Mousa S,Dandona P

更新日期：2001-08-01 00:00:00

abstract：:Aberrant crypt foci (ACF) have been identified on the colonic mucosal surface of rodents treated with colon carcinogens and of humans after methylene-blue staining and observation under a light microscope. Several lines of evidence strongly suggest that ACF with certain morphological, histological, cell kinetics, and ...

journal_title：Cell proliferation

authors： Roncucci L,Pedroni M,Vaccina F,Benatti P,Marzona L,De Pol A

更新日期：2000-02-01 00:00:00

abstract：OBJECTIVES:To evaluate the effects of rRNA synthesis inhibition on cell cycle progression and cell population growth according to the RB and p53 status. MATERIAL AND METHODS:RB- and p53-proficient U2OS cells and the RB- and p53-deficient SAOS-2 cells were used, rRNA transcription hindered by actinomycin D, and cell cy...

journal_title：Cell proliferation

authors： Montanaro L,Mazzini G,Barbieri S,Vici M,Nardi-Pantoli A,Govoni M,Donati G,Treré D,Derenzini M

更新日期：2007-08-01 00:00:00

abstract：:RAIDD (RIP-associated ICH-1 homologous protein with a death domain) is an adaptor molecule that mediates the action of cysteine proteases involved in apoptosis. To study the possibility of a novel system of cell ablation mediated by RAIDD, a preadipocyte cell line (3T3L1) was stably transfected with a plasmid containi...

journal_title：Cell proliferation

authors： Felmer R,Horvat S,Clinton M,Clark AJ

更新日期：2003-02-01 00:00:00

abstract：OBJECTIVES:Fibrotic cataract, including posterior capsule opacification (PCO) and anterior subcapsular cataract (ASC), renders millions of people visually impaired worldwide. However, the underlying mechanism remains poorly understood. Here, we report a miRNA-based regulatory pathway that controls pathological fibrosis...

journal_title：Cell proliferation

authors： Wang X,Wang L,Sun Y,Chen B,Xiong L,Chen J,Huang M,Wu J,Tan X,Zheng Y,Huang S,Liu Y

更新日期：2020-11-01 00:00:00

abstract：OBJECTIVES:MicroRNAs (miRNAs) as small non-coding RNA molecules act by negatively regulating their target genes. Recent studies have shown that protein phosphatase Mg2+/Mn2+-dependent 1F (PPM1F) plays a critical role in cancer metastasis. But, the regulation mechanisms of PPM1F by miRNAs in gastric cancer (GC) remain u...

journal_title：Cell proliferation

authors： Zhang J,Jin M,Chen X,Zhang R,Huang Y,Liu H,Zhu J

更新日期：2018-08-01 00:00:00

abstract：:Nerous system diseases, both central and peripheral, bring an incredible burden onto patients and enormously reduce their quality of life. Currently, there are still no effective treatments to repair nerve lesions that do not have side effects. Stem cell-based therapies, especially those using dental stem cells, bring...

journal_title：Cell proliferation

authors： Wang D,Wang Y,Tian W,Pan J

更新日期：2019-05-01 00:00:00

abstract：:The expression of the 170-kDa (alpha) and the 180-kDa (beta) isoforms of DNA topoisomerase II (topo II) was investigated with two specific monoclonal antibodies (MoAbs) in human peripheral blood lymphocytes (PBL), before and after phytohaemoagglutinin (PHA) stimulation. Binding of each MoAb was detected by indirect im...

journal_title：Cell proliferation

authors： Prosperi E,Negri C,Marchese G,Ricotti GC

更新日期：1994-05-01 00:00:00

abstract：OBJECTIVES:Stiffness of bone tissue differs response to its physiological or pathological status, such as osteoporosis or osteosclerosis. Consequently, the function of cells residing in bone tissue including osteoblasts (OBs), osteoclasts and osteocytes will be affected. However, to the best of our knowledge, the detai...

journal_title：Cell proliferation

authors： Zhang T,Lin S,Shao X,Zhang Q,Xue C,Zhang S,Lin Y,Zhu B,Cai X

更新日期：2017-06-01 00:00:00

abstract：:Spontaneously proliferating human leucocytes have been characterized and enumerated using multiparameter flow cytometry. The frequency of spontaneously proliferating cells amongst human peripheral blood mononuclear cells, was determined on the basis of BrdUrd incorporation and total DNA content in samples of cells inc...

journal_title：Cell proliferation

authors： Johannisson A,Amnéus H

更新日期：1993-07-01 00:00:00

abstract：INTRODUCTION/OBJECTIVES:The serine/threonine kinase homeodomain-interacting protein kinase 2 (HIPK2) is a co-regulator of an increasing number of transcription factors and cofactors involved in DNA damage response and development. We and others have cloned HIPK2 as an interactor of the p53 oncosuppressor, and have stud...

journal_title：Cell proliferation

authors： Iacovelli S,Ciuffini L,Lazzari C,Bracaglia G,Rinaldo C,Prodosmo A,Bartolazzi A,Sacchi A,Soddu S

更新日期：2009-06-01 00:00:00

abstract：:Differential display polymerase chain reaction (DD-PCR) is a powerful technique for comparing gene expression between cell types, or between stages of development or differentiation. Differentially expressed genes may be cloned and analysed further. Here we extend the use of DD-PCR to analyse differences in gene expre...

journal_title：Cell proliferation

authors： Keshav S,McKnight AJ,Arora R,Gordon S

更新日期：1997-10-01 00:00:00

abstract：OBJECTIVES:Steroid-induced osteonecrosis of the femoral head (ONFH) is a common orthopaedic disease of which early detection remains clinically challenging. Accumulating evidences indicated that circulating microRNAs (miRNAs) plays vital roles in the development of several bone diseases. However, the association betwee...

journal_title：Cell proliferation

authors： Li Z,Jiang C,Li X,Wu WKK,Chen X,Zhu S,Ye C,Chan MTV,Qian W

更新日期：2018-02-01 00:00:00

abstract：:Neural stem cells (NSCs) are early precursors of neuronal and glial cells. NSCs are capable of generating identical progeny through virtually unlimited numbers of cell divisions (cell proliferation), producing daughter cells committed to differentiation. Nuclear factor kappa B (NF-kappaB) is an inducible, ubiquitous t...

journal_title：Cell proliferation

authors： Piotrowska MJ,Widera D,Kaltschmidt B,an der Heiden U,Kaltschmidt C

更新日期：2006-12-01 00:00:00

abstract：OBJECTIVES:Generally, the secretory forms of FGF are known to regulate cell proliferation, differentiation and morphogenesis by binding to the extracellular domain of cell surface receptors. Intracellular FGFs (FGF11-14) are expressed principally in the nervous system. FGF13 is a microtubule-stabilizing protein that re...

journal_title：Cell proliferation

authors： Lu H,Shi X,Wu G,Zhu J,Song C,Zhang Q,Yang G

更新日期：2015-10-01 00:00:00

abstract：OBJECTIVES:Whole-tooth regeneration for tooth loss has long been a goal of dentistry. There is also an increasing demand to carry out pre-clinical in vitro and in vivo research methods in large animal model similar to human. The miniature pig has proven to be an alternative as a large mammal model owing to its many sim...

journal_title：Cell proliferation

authors： Wang F,Wu Z,Fan Z,Wu T,Wang J,Zhang C,Wang S

更新日期：2018-08-01 00:00:00

abstract：OBJECTIVES:Advanced head and neck carcinomas (HNCs) are aggressive tumours, mainly due to hypoxia and a cancer stem cell (CSC) subpopulation. The aim of this study was to simulate tumour growth and behaviour during radiotherapy of three HNC groups (governed by different growth kinetics, hypoxia levels and CSC division ...

journal_title：Cell proliferation

authors： Marcu LG,Marcu D,Filip SM

更新日期：2016-06-01 00:00:00

abstract：:Proliferation and multidrug resistance status are key predictors of therapeutic outcome in acute myeloid leukaemia (AML). Anthracyclines such as daunorubicin (DNR) are typically used to treat AML and can induce drug resistance. The goal of the studies described here was to select a combination of fluorescent probes th...

journal_title：Cell proliferation

authors： Boutonnat J,Barbier M,Muirhead K,Mousseau M,Ronot X,Seigneurin D

更新日期：1999-08-01 00:00:00

abstract：OBJECTIVE:Accumulating data show that dysregulation of long noncoding RNAs (lncRNAs) acts a critical role in a variety of malignancies. Among these lncRNAs, small nucleolar RNA host genes (SNHGs) are associated with tumour growth and progression. But, the molecular mechanisms by which SNHG4 contributes to osteosarcoma ...

journal_title：Cell proliferation

authors： Xu R,Feng F,Yu X,Liu Z,Lao L

更新日期：2018-12-01 00:00:00

abstract：OBJECTIVES:To investigate the function and regulatory mechanism of Krüppel-like factor 3 (KLF3) in lung cancer. MATERIALS AND METHODS:KLF3 expression was analysed by qRT-PCR and Western blot assays. The proliferation, migration, invasion, cycle and apoptosis were measured by CCK-8 and EdU, wound-healing and Transwell,...

journal_title：Cell proliferation

authors： Wang R,Xu J,Xu J,Zhu W,Qiu T,Li J,Zhang M,Wang Q,Xu T,Guo R,Lu K,Yin Y,Gu Y,Zhu L,Huang P,Liu P,Liu L,De W,Shu Y

更新日期：2019-03-01 00:00:00

abstract：:The relationship of cyclin-dependent kinase inhibitor 3 (CDKN3) with tumours has previously been presented in a number of publications. However, the molecular network and interpretation of CDKN3 through the cell cycle between non-malignancy associated hepatitis/cirrhosis and hepatocellular carcinoma (HCC) have remaine...

journal_title：Cell proliferation

authors： Wang L,Sun L,Huang J,Jiang M

更新日期：2011-06-01 00:00:00

abstract：OBJECTIVES:Osteopetrosis is a rare inherited skeletal disease characterized by increased bone mineral density due to the loss of osteoclast function or differentiation potential. MATERIALS AND METHODS:The study involved a Chinese patient with osteopetrosis (the proband) and her immediate family members and 180 control...

journal_title：Cell proliferation

authors： Yuan Y,Yang L,Liu T,Zhang H,Lu Q

更新日期：2019-11-01 00:00:00

abstract：OBJECTIVES:The bone tissue engineering primarily focuses on three-dimensional co-culture systems, which physical and biological properties resemble the cell matrix of actual tissues. The complex dialogue between bone-forming and endothelial cells (ECs) in a tissue-engineered construct will directly regulate angiogenesi...

journal_title：Cell proliferation

authors： Li L,Li J,Zou Q,Zuo Y,Cai B,Li Y

更新日期：2019-09-01 00:00:00

abstract：:Laminin-2 (LN-2, alpha2beta1gamma1) is a basement membrane-associated laminin isoform usually considered in the context of muscle and nerve tissues. To test the hypothesis that LN-2 can additionally modulate epithelial cell biology, an analysis of the role of LN-2 in cell adhesion, activation of signalling intermediat...

journal_title：Cell proliferation

authors： Dowgiert J,Sosne G,Kurpakus-Wheater M

更新日期：2004-04-01 00:00:00

abstract：:Estimates of the clonogen content (number of microcolony-forming cells) of murine intestinal crypts using microcolony assays show an apparent dependence on the radiation dose used in the assay of clonogen content. Crypt radiation survival curves often show increased curvature beyond that expected on the basis of the c...

journal_title：Cell proliferation

authors： Roberts SA,Hendry JH,Potten CS

更新日期：2003-08-01 00:00:00

abstract：OBJECTIVE:To determine the inhibitory effect and mechanism of Notch signalling on adipogenesis of mouse adipose-derived stem cells (mASCs). MATERIALS AND METHODS:Varied concentrations of N-[N-(3,5-difluorophenacetyl)-l-alanyl]-S-phenylglycine t-butylester (DAPT) were added to mASCs 3 days before adipogenic induction w...

journal_title：Cell proliferation

authors： Huang Y,Yang X,Wu Y,Jing W,Cai X,Tang W,Liu L,Liu Y,Grottkau BE,Lin Y

更新日期：2010-04-01 00:00:00