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An evaluation of the Xpert MTB/RIF assay and detection of false-positive rifampicin resistance in Mycobacterium tuberculosis.

Abstract：

:Recent reports suggest that false-positive rifampicin resistance may be assigned by the Xpert MTB/RIF assay. We analysed 169 specimens using the MTB/RIF assay. Using culture as the gold standard, we found that the assay had 100% sensitivity and specificity for detecting M. tuberculosis. However, we found that the assay incorrectly assigned rifampicin resistance in 4/13 (31%) of cases.

journal_name

Diagn Microbiol Infect Dis

journal_title

Diagnostic microbiology and infectious disease

authors

Williamson DA,Basu I,Bower J,Freeman JT,Henderson G,Roberts SA

doi

10.1016/j.diagmicrobio.2012.06.013

subject

Has Abstract

pub_date

2012-10-01 00:00:00

pages

207-9

issue

2

eissn

0732-8893

issn

1879-0070

pii

S0732-8893(12)00262-3

journal_volume

74

pub_type

杂志文章

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