Abstract:
:Very little is known about the alcohol elimination rates of newborns who have had chronic alcohol exposure in utero. In these case reports, blood alcohol levels were taken immediately before delivery, at delivery, and postdelivery for 2 mothers who drank alcohol during their pregnancies and 3 single-birth newborns. Newborn A1 of Mother A had no physical characteristics of fetal alcohol syndrome (FAS). The initial blood alcohol level for this newborn was 38.4 mg/dL 129 minutes after birth, with a subsequent blood alcohol level of 5.5 mg/dL 304 minutes after delivery, resulting in an alcohol elimination rate of 11.3 mg/dL per hour. The blood alcohol level for Mother A was 87.4 mg/dL 66 minutes before delivery. Newborn A2 of mother A had FAS. Sixty minutes after delivery, the blood alcohol level for this newborn was 39.5 mg/dL, and the alcohol level of the mother was 42.1 mg/dL. Newborn B1 of mother B had FAS. At 67 minutes after birth, newborn B1 had a blood alcohol level of 246.5 mg/dL, which dropped to 178.7 mg/dL 302 minutes after birth, resulting in an alcohol elimination rate of 17.3 mg/dL per hour. This alcohol elimination rate is within the metabolism range (15-49 mg/dL per hour) of adults with alcoholism. The maternal blood alcohol level was 265.9 mg/dL 27 minutes before delivery. Blood alcohol levels drawn on both the mother and newborn at delivery and 2 or 3 hourly follow-up levels can provide evidence that fetal alcohol dehydrogenase activity is induced by chronic maternal alcohol use.
journal_name
Pediatricsjournal_title
Pediatricsauthors
Kvigne VL,Randall B,Simanton EG,Brenneman G,Welty TKdoi
10.1542/peds.2011-1400subject
Has Abstractpub_date
2012-10-01 00:00:00pages
e1015-8issue
4eissn
0031-4005issn
1098-4275pii
peds.2011-1400journal_volume
130pub_type
杂志文章相关文献
PEDIATRICS文献大全abstract::Data for this article, as in previous reports, are drawn principally from the Monthly Vital Statistics Report, published by the National Center for Health Statistics. The international data come from the Demographic Yearbook and the quarterly Population and Vital Statistics Report, both published by the Statistical Of...
journal_title:Pediatrics
pub_type: 杂志文章
doi:
更新日期:1983-12-01 00:00:00
abstract:OBJECTIVE:The current recommendation for choosing an appropriate size cuff for measuring blood pressure (BP) is a bladder width to equal 40% of the upper arm circumference (UAC). However, most physicians use the older two-thirds or three-fourths upper arm length (UAL) recommendations to choose a cuff. The aim of this s...
journal_title:Pediatrics
pub_type: 杂志文章
doi:10.1542/peds.110.5.920
更新日期:2002-11-01 00:00:00
abstract:OBJECTIVES:Respiratory infections (RIs) are an important cause of morbidity and excessive antibiotic prescriptions in children attending day care centers (DCCs). We aimed to assess the effectiveness of an educational and hand hygiene program in DCCs and homes in reducing RI incidence and antibiotic prescriptions in chi...
journal_title:Pediatrics
pub_type: 杂志文章,随机对照试验
doi:10.1542/peds.2018-1245
更新日期:2018-11-01 00:00:00
abstract:BACKGROUND:In past decades, numerous population- and hospital-based studies have revealed a relationship between migraine or headache and psychopathology in children. OBJECTIVE:To describe and assess all clinical studies on the prevalence and manifestations of psychological functioning and psychiatric comorbidity in c...
journal_title:Pediatrics
pub_type: 杂志文章,评审
doi:10.1542/peds.2009-3293
更新日期:2010-08-01 00:00:00
abstract:BACKGROUND:Much effort has been directed toward increasing the training of physicians from underrepresented minority groups, yet few direct comparisons have examined the diversity of the racial/ethnic backgrounds of the physicians relative to the patient populations they serve, either currently or into the future. This...
journal_title:Pediatrics
pub_type: 杂志文章
doi:10.1542/peds.105.1.27
更新日期:2000-01-01 00:00:00
abstract::The confusing area of cow's milk intolerance is explored in an attempt to define the various mechanisms whereby milk affects gastrointestinal function, resulting in clinical symptoms (diarrhea, vomiting, gastrointestinal bleeding, etc.). The adverse reaction of infants to cow's milk ingestion may relate to lactose int...
journal_title:Pediatrics
pub_type: 杂志文章
doi:
更新日期:1977-10-01 00:00:00
abstract:OBJECTIVES:This article reports on the progress made in addressing pediatric medical device needs through the establishment of the Pediatric Device Consortia Grant Program. Pediatric practitioners should be aware of both the imperative for well-studied devices for children and the existence of recently created resource...
journal_title:Pediatrics
pub_type: 杂志文章
doi:10.1542/peds.2012-1534
更新日期:2013-05-01 00:00:00
abstract::It is common practice to use endotracheal continuous positive airway pressure for various time periods up to 24 hours before attempting extubation in infants who are mechanically ventilated. A few studies in newborns have indicated that airway resistance is increased through small endotracheal tubes. This increases th...
journal_title:Pediatrics
pub_type: 临床试验,杂志文章,随机对照试验
doi:
更新日期:1987-09-01 00:00:00
abstract:BACKGROUND AND OBJECTIVE:Primary disabilities in children prenatally exposed to alcohol have a major impact on their daily life. It is suggested that these issues persist into adulthood, but few studies have addressed the outcome in adults with prenatal exposure, especially those with fetal alcohol syndrome (FAS). The ...
journal_title:Pediatrics
pub_type: 杂志文章
doi:10.1542/peds.2014-1915
更新日期:2015-01-01 00:00:00
abstract:BACKGROUND:Neonatal encephalopathy (NE) is a major predictor of death and long-term neurologic disability, but there are few studies of antecedents of NE. OBJECTIVES:To identify antecedents in a large registry of infants who had NE. METHODS:This was a maternal and infant record review of 4165 singleton neonates, gest...
journal_title:Pediatrics
pub_type: 杂志文章
doi:10.1542/peds.2012-0714
更新日期:2012-11-01 00:00:00
abstract::With a randomized clinical trial, the possibility was assessed that a tracheal instillation of pulmonary surfactant prior to the first breath might prevent the development of some of the signs of neonatal respiratory distress syndrome. Of the 72 infants in the trial, all born at a gestational age of less than 30 weeks...
journal_title:Pediatrics
pub_type: 临床试验,杂志文章,随机对照试验
doi:
更新日期:1985-08-01 00:00:00
abstract:OBJECTIVE:The purpose of this work was to evaluate whether education about zinc supplements and provision of zinc supplements to caregivers is effective in the treatment of acute diarrhea and whether this strategy adversely affects the use of oral rehydration salts. PATIENTS AND METHODS:Six clusters of 30,000 people e...
journal_title:Pediatrics
pub_type: 杂志文章,随机对照试验
doi:10.1542/peds.2007-1939
更新日期:2008-05-01 00:00:00
abstract:BACKGROUND:The evidence that atherosclerosis begins during adolescence has led to the belief that primary prevention of cardiovascular disease (CHD) should commence in childhood. Although several national guidelines have been issued for the detection and treatment of CHD risk factors in children, concerns continue to b...
journal_title:Pediatrics
pub_type: 杂志文章
doi:10.1542/peds.102.5.e50
更新日期:1998-11-01 00:00:00
abstract:BACKGROUND:Introduction of the heptavalent pneumococcal conjugate vaccine (PCV7) changed the epidemiology of invasive pneumococcal disease (IPD). We evaluated the changes that occurred after PCV7 introduction among Utah infants aged 1 to 90 days, too young to be fully immunized. METHODS:We identified children <18 year...
journal_title:Pediatrics
pub_type: 杂志文章
doi:10.1542/peds.2012-3900
更新日期:2013-07-01 00:00:00
abstract:OBJECTIVE:To assess the effects of procedural techniques, local anesthetic use, and postgraduate training level on lumbar puncture (LP) success rates. METHODS:In this prospective observational study, medical students and residents ("trainees") reported techniques used for infant LPs in an urban teaching emergency depa...
journal_title:Pediatrics
pub_type: 杂志文章
doi:10.1542/peds.2005-0519
更新日期:2006-03-01 00:00:00
abstract:BACKGROUND:The impact of secondhand marijuana smoke exposure on children is unknown. New methods allow for the detection of marijuana smoke exposure in children. METHODS:We studied children who were hospitalized in Colorado and had a parent participating in a smoking cessation study; all children had urine samples rem...
journal_title:Pediatrics
pub_type: 杂志文章
doi:10.1542/peds.2018-0820
更新日期:2018-12-01 00:00:00
abstract::Despite substantial progress, adolescents remain at high risk for human immunodeficiency virus (HIV) infection. Two independent random digit dial statewide Massachusetts surveys of 16- to 19-year-old persons conducted August through September 1986 and 1988 revealed that the proportion of teenagers who had discussed ac...
journal_title:Pediatrics
pub_type: 杂志文章
doi:
更新日期:1990-01-01 00:00:00
abstract:BACKGROUND:Sleep deprivation and sleepiness are associated with poorer school performance, impaired neurobehavioral functioning, and behavioral problems. OBJECTIVE:To determine if adolescents with high levels of sleepiness or short sleep duration have impaired executive functioning. METHODS:Ours was a cross-sectional...
journal_title:Pediatrics
pub_type: 杂志文章
doi:10.1542/peds.2008-1182
更新日期:2009-04-01 00:00:00
abstract:BACKGROUND:We evaluated whether younger age in class is associated with poorer academic performance and an increased risk of being prescribed stimulants for attention-deficit/hyperactivity disorder (ADHD). METHODS:This was a nationwide population-based cohort study, linking data from national registries of prescribed ...
journal_title:Pediatrics
pub_type: 杂志文章
doi:10.1542/peds.2012-0689
更新日期:2012-12-01 00:00:00
abstract:OBJECTIVE:We examined the association between state Medicaid and State Children's Health Insurance Program (SCHIP) income eligibility and the financial burden reported by low-income families raising children with special health care needs (CSHCN). SAMPLE AND METHODS:Data on low-income CSHCN and their families were fro...
journal_title:Pediatrics
pub_type: 杂志文章
doi:10.1542/peds.2009-1255P
更新日期:2009-12-01 00:00:00
abstract:OBJECTIVE:Although one third of young adults in the United States are uninsured, lack of insurance in this age group has been the subject of few published studies. Because opportunities to obtain public and private insurance are likely to differ for men and women, the objective of this study was to describe the gender-...
journal_title:Pediatrics
pub_type: 杂志文章
doi:10.1542/peds.113.2.291
更新日期:2004-02-01 00:00:00
abstract::In 2005, the Enhancing Developmentally Oriented Primary Care (EDOPC) project of the Illinois chapter of the American Academy of Pediatrics and the Illinois Department of Healthcare and Family Services began a project to improve the delivery and financing of preventive health and developmental services for children in ...
journal_title:Pediatrics
pub_type: 杂志文章
doi:10.1542/peds.2010-1466K
更新日期:2010-12-01 00:00:00
abstract::Neutropenia developed in three pediatric patients treated intravenously with nafcillin. This association has not been, to our knowledge, previously reported in children. One of the patients is the youngest reported who had neutropenia associated with any penicillin; another patient had a prolonged recovery. The litera...
journal_title:Pediatrics
pub_type: 杂志文章
doi:
更新日期:1978-01-01 00:00:00
abstract::In this report we present two infants with congenital myotonic dystrophy (CMD) who were successfully weaned from prolonged ventilatory support using nasal continuous positive airway pressure (N-CPAP). The first infant received 127 days of endotracheal mechanical ventilation as part of 141 days of total ventilatory sup...
journal_title:Pediatrics
pub_type: 杂志文章
doi:10.1542/peds.101.4.704
更新日期:1998-04-01 00:00:00
abstract::The Federation of Pediatric Organizations engaged members of the pediatric community in an 18-month process to envision the future of the workforce in pediatrics, culminating in a Visioning Summit on the Future of the Workforce in Pediatrics. This article documents the planning process and methods used. Four working g...
journal_title:Pediatrics
pub_type: 杂志文章
doi:10.1542/peds.2014-3493
更新日期:2015-07-01 00:00:00
abstract:OBJECTIVES:To evaluate the relationship between the severity of necrotizing enterocolitis (NEC) and circulating concentrations of proinflammatory cytokines interleukin (IL)-1beta and IL-8 and counterinflammatory cytokines IL-1 receptor antagonist (IL-1ra) and IL-10. These cytokines have been associated with bowel injur...
journal_title:Pediatrics
pub_type: 杂志文章
doi:10.1542/peds.103.4.766
更新日期:1999-04-01 00:00:00
abstract:OBJECTIVES:There is no safe or risk-free level of tobacco use or tobacco smoke exposure. In this randomized controlled trial, we tested a tobacco control intervention in families and specifically evaluated a tailored cessation intervention for the parents and/or caregivers (Ps/Cs) who were smokers while their children ...
journal_title:Pediatrics
pub_type: 杂志文章,随机对照试验
doi:10.1542/peds.2017-1026M
更新日期:2018-01-01 00:00:00
abstract:OBJECTIVE:To examine the association between sweet drink consumption and overweight among preschool children. METHODS:A retrospective cohort design was used to examine the association between sweet drink consumption and overweight at follow-up among 10904 children who were aged 2 and 3 years and had height, weight, an...
journal_title:Pediatrics
pub_type: 杂志文章
doi:10.1542/peds.2004-1148
更新日期:2005-02-01 00:00:00
abstract:BACKGROUND AND OBJECTIVES:Rates of adult women receiving contraceptive provision when simultaneously prescribed a known teratogen are alarmingly low. The prevalence of this behavior among pediatric providers and their adolescent patients is unknown. The objective of this study was to describe pediatric provider behavio...
journal_title:Pediatrics
pub_type: 杂志文章
doi:10.1542/peds.2015-1454
更新日期:2016-01-01 00:00:00
abstract:BACKGROUND:Investigative efforts to improve monitoring during sedation for patients of all ages are part of a national agenda for patient safety. According to the Institute of Medicine, recent technological advances in patient monitoring have contributed to substantially decreased mortality for people receiving general...
journal_title:Pediatrics
pub_type: 杂志文章,随机对照试验
doi:10.1542/peds.2005-1709
更新日期:2006-06-01 00:00:00