当前位置： SCI文献检索 > DIABETES RESEARCH AND CLINICAL PRACTICE期刊下所有文献 > Prevalence and severity of diabetic retinopathy in patients attending the endocrinology diabetes clinic at Mulago Hospital in Uganda.

Prevalence and severity of diabetic retinopathy in patients attending the endocrinology diabetes clinic at Mulago Hospital in Uganda.

Abstract：

AIMS:The epidemiology for diabetic retinopathy (DR) has been well described in the western population. Countries in Sub-Saharan Africa have attempted to identify the prevalence of diabetic eye disease, however, there still remains a degree of paucity across the continent due to inadequacy in health system organisations and resource poor settings. We aimed to identify the severity and prevalence of DR and maculopathy of patients attending the diabetes clinic at Mulago Hospital, Kampala, Uganda. METHODS:A cross-sectional observational study of 44 patients who attended a diabetes clinic at Mulago Hospital in April 2016. Parameters measured included visual acuity (VA) using a Snellen chart, blood glucose (mmol/l) and blood pressure (mmHg). Screening for DR grading was carried out with indirect fundoscopy and retinal photograph. Only the highest graded eye of retinopathy of each patient was included. RESULTS:A total of 41 eyes from 41 patients were included. Of these patients 15 were male. The average age of patients was 50.4 years. Six eyes (14.6%) had a VA < 6/18. Prevalence of DR was 19.5% (8 eyes) and 14.6% (6 eyes) had maculopathy. Of all eyes 14.6% had sight-threatening retinopathy, which was 85.7% of total cases of retinopathy in our study. CONCLUSIONS:We observed a high prevalence of DR and maculopathy, particularly sight threatening retinopathy, considering the proportion of patients screened. There is a need for a co-ordinated diabetes screening service through integration of the diabetes clinic and eye clinic at Mulago Hospital to better identify and treat this sight-threatening condition.

journal_name

Diabetes Res Clin Pract

journal_title

Diabetes research and clinical practice

authors

Magan T,Pouncey A,Gadhvi K,Katta M,Posner M,Davey C

doi

10.1016/j.diabres.2019.04.024

subject

Has Abstract

pub_date

2019-06-01 00:00:00

pages

65-70

eissn

0168-8227

issn

1872-8227

pii

S0168-8227(19)30256-6

journal_volume

152

pub_type

杂志文章

相关文献

DIABETES RESEARCH AND CLINICAL PRACTICE文献大全
  • Prevention of type 2 diabetes: a review.

    abstract：:One of the major public health challenges of the 21st century is type 2 diabetes. WHO estimates that by 2025 as many as 200-300 million people worldwide will have developed the disease. A distressing increase in children is perhaps the most alarming sign of something going wrong. Roughly half of the risk of type 2 dia...

    journal_title：Diabetes research and clinical practice

    pub_type： 杂志文章,评审

    doi：10.1016/j.diabres.2006.09.020

    authors： Hussain A,Claussen B,Ramachandran A,Williams R

    更新日期：2007-06-01 00:00:00

  • Glycaemia and utilisation of technology across the lifespan of adults with type 1 diabetes: Results of the Australian National Diabetes Audit (ANDA).

    abstract：AIMS:To evaluate the utilisation of technologies and associated glycaemia among adults with type 1 diabetes. METHODS:De-identified data from adults with type 1 diabetes (≥18 years old) in the Australian National Diabetes Audit (ANDA)-2019 were analysed. Proportions using insulin pumps or injections with continuous glu...

    journal_title：Diabetes research and clinical practice

    pub_type： 杂志文章

    doi：10.1016/j.diabres.2020.108609

    authors： Pease A,Szwarcbard N,Earnest A,Andrikopoulos S,Wischer N,Zoungas S

    更新日期：2020-12-10 00:00:00

  • Gastric emptying in health and type 2 diabetes: An evaluation using a 75 g oral glucose drink.

    abstract：AIM:Gastric emptying is a major determinant of the glycaemic response to carbohydrate and is frequently abnormal in type 2 diabetes (T2DM). There is little information about how chronic glycaemic control affects gastric emptying in T2DM. We evaluated gastric emptying of a 75 g glucose drink in community-based patients ...

    journal_title：Diabetes research and clinical practice

    pub_type： 杂志文章

    doi：10.1016/j.diabres.2020.108610

    authors： Xie C,Huang W,Wang X,Trahair LG,Pham HT,Marathe CS,Young RL,Jones KL,Horowitz M,Rayner CK,Wu T

    更新日期：2020-12-07 00:00:00

  • Intensity-related exercise albuminuria in insulin dependent diabetic patients.

    abstract：:Normoalbuminuric insulin-dependent diabetic (IDDM) patients may present higher rates of urinary albumin excretion after submaximal exercise at a standard intensity. To evaluate whether the urinary albumin excretion of IDDM patients is increased after maximal and submaximal exercise when exercise intensities are adjust...

    journal_title：Diabetes research and clinical practice

    pub_type： 杂志文章

    doi：10.1016/0168-8227(93)90117-n

    authors： Bertoluci MC,Friedman G,Schaan BD,Ribeiro JP,Schmid H

    更新日期：1993-03-01 00:00:00

  • Ten-year incidence of diabetic retinopathy and macular edema. Risk factors in a sample of people with type 1 diabetes.

    abstract：AIMS:To determine the 10-year incidence of diabetic retinopathy (DR) and macular edema (DME), and its relationship with its risk factors in a sample of type 1 diabetes mellitus. METHODS:A total of 334 patients without diabetic retinopathy at baseline underwent a 10-year prospective study, the risk factors included: ag...

    journal_title：Diabetes research and clinical practice

    pub_type： 杂志文章

    doi：10.1016/j.diabres.2011.07.004

    authors： Romero-Aroca P,Baget-Bernaldiz M,Fernandez-Ballart J,Plana-Gil N,Soler-Lluis N,Mendez-Marin I,Bautista-Perez A

    更新日期：2011-10-01 00:00:00

  • Clustering of components of the metabolic syndrome and risk for development of type 2 diabetes in Japanese male office workers.

    abstract：:To investigate the effects of the clustering of components of the metabolic syndrome (MS) on development of diabetes, we examined 3298 Japanese male office workers aged 35-59 years who did not have type 2 diabetes (a fasting plasma glucose level of > or =7.0 mmol/l or receipt of hypoglycemic medication) or a history o...

    journal_title：Diabetes research and clinical practice

    pub_type： 杂志文章

    doi：10.1016/j.diabres.2003.08.007

    authors： Nakanishi N,Nishina K,Okamoto M,Yoshida H,Matsuo Y,Suzuki K,Tatara K

    更新日期：2004-03-01 00:00:00

  • Ramadan fasting in people with type 1 diabetes during COVID-19 pandemic: The DaR Global survey.

    abstract：OBJECTIVES:The DaR Global survey was conducted to determine the impact of the COVID-19 pandemic on the intentions to fast and the outcomes of fasting in <18 years versus ≥18 years age groups with type 1 diabetes mellitus (T1DM). METHODS:Muslim people with T1DM were surveyed in 13 countries between June and August 2020...

    journal_title：Diabetes research and clinical practice

    pub_type： 杂志文章

    doi：10.1016/j.diabres.2020.108626

    authors： Hassanein M,Alamoudi RM,Kallash MA,Aljohani NJ,Alfadhli EM,Tony LE,Khogeer GS,Alfadhly AF,Khater AE,Ahmedani MY,Buyukbese MA,Shaltout I,Belkhadir J,Hafidh K,Chowdhury TA,Hussein Z,Elbarbary NS

    更新日期：2020-12-13 00:00:00

  • Glucose variability, blood pressure and arterial stiffness in type 1 diabetes.

    abstract：AIMS:Evidence suggests that chronic hyperglycaemia predicts not only microvascular disease but also macrovascular disease, however it is not known whether it is the glucose variability per se or the total glucose exposure that confers risk. The objective of this study was to investigate whether daily glucose variabilit...

    journal_title：Diabetes research and clinical practice

    pub_type： 杂志文章

    doi：10.1016/j.diabres.2008.01.010

    authors： Gordin D,Rönnback M,Forsblom C,Mäkinen V,Saraheimo M,Groop PH

    更新日期：2008-06-01 00:00:00

  • Premature loss of muscle mass and function in type 2 diabetes.

    abstract：INTRODUCTION:Muscle mass and function are among the most relevant factors that contribute to an optimal quality of life, and are strong predictors of mortality in the elderly. Loss of lean tissues and deterioration of muscle function have been described as one of the many complications of type 2 diabetes mellitus (DM2)...

    journal_title：Diabetes research and clinical practice

    pub_type： 杂志文章

    doi：10.1016/j.diabres.2016.04.011

    authors： Guerrero N,Bunout D,Hirsch S,Barrera G,Leiva L,Henríquez S,De la Maza MP

    更新日期：2016-07-01 00:00:00

  • Waist circumference cut-off points for the diagnosis of metabolic syndrome in Iranian adults.

    abstract：AIMS:Central obesity, a prominent feature of metabolic syndrome (MetS), is commonly assessed by gender- and ethnicity-specific waist circumference (WC) cut-off values. Since 2006, the recommended WC cut-offs by the International Diabetes Federation (IDF) for Europeans are used in Iran because of limited data availabili...

    journal_title：Diabetes research and clinical practice

    pub_type： 杂志文章

    doi：10.1016/j.diabres.2008.07.009

    authors： Esteghamati A,Ashraf H,Rashidi A,Meysamie A

    更新日期：2008-10-01 00:00:00

  • Reduced lung diffusion capacity in type 2 diabetes is independent of heart failure.

    abstract：:In a case-control analysis comparing 303 patients with diabetes and 303 without (matched on age, race, sex and height), diabetics had reduced lung diffusion (DLCO) independent of smoking, obesity, clinical heart failure, asymptomatic left ventricular systolic and diastolic dysfunction: DLCO (mean±SE: 15.5±0.9 vs. 16.4...

    journal_title：Diabetes research and clinical practice

    pub_type： 杂志文章

    doi：10.1016/j.diabres.2012.02.014

    authors： Klein OL,Jones M,Lee J,Collard HR,Smith LJ

    更新日期：2012-06-01 00:00:00

  • Development and validation of PRISM: a survey tool to identify diabetes self-management barriers.

    abstract：AIMS:Although most children with type 1 diabetes do not achieve optimal glycemic control, no systematic method exists to identify and address self-management barriers. This study develops and validates PRISM (Problem Recognition in Illness Self-Management), a survey-based tool for efficiently identifying self-managemen...

    journal_title：Diabetes research and clinical practice

    pub_type： 杂志文章

    doi：10.1016/j.diabres.2014.01.015

    authors： Cox ED,Fritz KA,Hansen KW,Brown RL,Rajamanickam V,Wiles KE,Fate BH,Young HN,Moreno MA

    更新日期：2014-04-01 00:00:00

  • Revisiting the efficacy of long-acting insulin analogues on adults with type 1 diabetes using mixed-treatment comparisons.

    abstract：AIM:To perform a network meta-analysis between long-acting insulin analogues (glargine and detemir) and Neutral Protamine Hagedorn (NPH) insulin on adults with type 1 diabetes. METHODS:A systematic review of the literature was conducted according to the Cochrane Collaboration guidelines. The search for randomized cont...

    journal_title：Diabetes research and clinical practice

    pub_type： 杂志文章,评审

    doi：10.1016/j.diabres.2011.09.001

    authors： Sanches AC,Correr CJ,Venson R,Pontarolo R

    更新日期：2011-12-01 00:00:00

  • The characteristic of cognitive function in Type 2 diabetes mellitus.

    abstract：AIM:To identify characteristics of neuropsychological function among elderly individuals with Type 2 diabetes mellitus with mild cognitive impairment (T2DM-MCI) and evaluate domain-specific effects of T2DM on cognition. METHODS:This was a cross-sectional study conducted in Tianjin, China. MCI subjects (n=246) and cont...

    journal_title：Diabetes research and clinical practice

    pub_type： 杂志文章

    doi：10.1016/j.diabres.2015.05.019

    authors： Gao Y,Xiao Y,Miao R,Zhao J,Zhang W,Huang G,Ma F

    更新日期：2015-08-01 00:00:00

  • Long-term outcomes associated with triple-goal achievement in patients with type 2 diabetes mellitus (T2DM).

    abstract：AIMS:This study was designed to compare the risk of long-term health outcomes, including microvascular, macrovascular complications and mortality, across 4 cohorts: triple-goal, dual-goal, single-goal, and no-goal achievers. METHODS:A retrospective cohort of 53,120 patients with T2DM were identified (97.51% male, 61.4...

    journal_title：Diabetes research and clinical practice

    pub_type： 杂志文章

    doi：10.1016/j.diabres.2018.02.013

    authors： Shi Q,Liu S,Krousel-Wood M,Shao H,Fonseca V,Shi L

    更新日期：2018-06-01 00:00:00

  • Adherence to postpartum diabetes mellitus screening, do associated pregnancy complications make a difference?

    abstract：AIMS:We aimed to investigate the impact of Gestational Diabetes Mellitus (GDM) complications on compliance with postpartum Diabetes screening. METHODS:A retrospective cohort study was conducted comparing screening rates of women with and without GDM associated complications who delivered at the Soroka University Medic...

    journal_title：Diabetes research and clinical practice

    pub_type： 杂志文章

    doi：10.1016/j.diabres.2019.107972

    authors： Rotem R,Salem-Yaniv S,Sandler-Rahat H,Yohay D,Sade S,Yahav L,Weintraub AY

    更新日期：2020-01-01 00:00:00

  • Changes in apoptosis and Bcl-2 expression in human hyperglycemic, term placental trophoblast.

    abstract：:Apoptosis and its associated regulatory mechanisms are physiological events crucial to the maintenance of placental homeostasis; imbalance of these processes, however, such as occurs under various pathological conditions, may compromise placenta function and, consequently, pregnancy success. Increased apoptosis occurs...

    journal_title：Diabetes research and clinical practice

    pub_type： 杂志文章

    doi：10.1016/j.diabres.2005.12.014

    authors： Sgarbosa F,Barbisan LF,Brasil MA,Costa E,Calderon IM,Gonçalves CR,Bevilacqua E,Rudge MV

    更新日期：2006-08-01 00:00:00

  • The metabolic syndrome in Australia: prevalence using four definitions.

    abstract：OBJECTIVE:To compare the prevalence of the Metabolic Syndrome (MetS) defined by four definitions and to determine which definition best identifies those at high cardiovascular disease (CVD) risk and with insulin resistance. METHODS:AusDiab is a population-based survey of 11,247 Australians. Participants had anthropome...

    journal_title：Diabetes research and clinical practice

    pub_type： 杂志文章

    doi：10.1016/j.diabres.2007.02.002

    authors： Cameron AJ,Magliano DJ,Zimmet PZ,Welborn T,Shaw JE

    更新日期：2007-09-01 00:00:00

  • Association of serum apolipoprotein C III levels and apolipoprotein C III gene Sst I polymorphism with carotid intima-media thickness in Chinese type 2 diabetic patients.

    abstract：:Apolipoprotein C III (apo C III) plays a central role in regulating plasma metabolism of triglyceride-rich lipoprotein (TRL). The G3238C allele (Sst I) in the 3'-untranslated region has been found to be associated with raised apo C III levels and hypertriglyceridemia (HTG). Some studies suggest that apo C III and the ...

    journal_title：Diabetes research and clinical practice

    pub_type： 杂志文章

    doi：10.1016/j.diabres.2004.02.020

    authors： Chen X,Tian H,Liu R

    更新日期：2004-10-01 00:00:00

  • Health-related quality-of-life implications of cardiovascular events in individuals with type 2 diabetes mellitus: A subanalysis from the Saxagliptin Assessment of Vascular Outcomes Recorded in Patients with Diabetes Mellitus (SAVOR)-TIMI 53 trial.

    abstract：BACKGROUND:The impact of cardiovascular complications on health-related quality-of-life (HRQoL) in type 2 diabetes mellitus has not been clearly established. Using EQ5D utility data from SAVOR-TIMI 53, a large phase IV trial of saxagliptin versus placebo, we quantified the impact of cardiovascular and other major event...

    journal_title：Diabetes research and clinical practice

    pub_type： 杂志文章

    doi：10.1016/j.diabres.2016.12.019

    authors： Briggs AH,Bhatt DL,Scirica BM,Raz I,Johnston KM,Szabo SM,Bergenheim K,Mukherjee J,Hirshberg B,Mosenzon O

    更新日期：2017-08-01 00:00:00

  • Beta(3)-adrenergic receptor gene variant is associated with upper body obesity only in obese Japanese-American men but not in women.

    abstract：:We investigated gender differences in the relationships between the Trp64Arg variant of the beta(3)-adrenergic receptor (AR) gene in obesity and insulin resistance in nondiabetic subjects. In 476 nondiabetic Japanese-Americans (M/F=204/272), the Trp64Arg variant of the beta(3)-AR gene was examined. The presence or abs...

    journal_title：Diabetes research and clinical practice

    pub_type： 杂志文章

    doi：10.1016/s0168-8227(01)00284-4

    authors： Kawamura T,Egusa G,Fujikawa R,Okubo M

    更新日期：2001-10-01 00:00:00

  • Impaired fasting plasma glucose is a risk indicator of interventricular septum thickening among non-diabetic subjects with obesity.

    abstract：AIMS:To evaluate whether progressively higher fasting plasma glucose (FPG) is associated to thickening of the interventricular septum (IVS) among non-diabetic subjects with obesity. METHODOLOGY:We studied 227 consecutive non diabetic patients (155 women and 72 men, age range 18-72 years) with overweight or obesity (BM...

    journal_title：Diabetes research and clinical practice

    pub_type： 杂志文章

    doi：10.1016/j.diabres.2020.108436

    authors： Zupo R,Castellana F,Sardone R,Scicchitano P,Lampignano L,Ciccone MM,Triggiani V,Guastamacchia E,Giannelli G,De Pergola G

    更新日期：2020-11-01 00:00:00

  • Leukocyte telomere length correlates with glucose control in adults with recently diagnosed type 2 diabetes.

    abstract：AIMS:We investigated leukocyte relative telomere length (TL) in patients with type 2 diabetes (T2D) diagnosed for no longer than five years and its association with clinical and biochemical variables. METHODS:Peripheral blood leukocyte relative TL was investigated in 108 patients with T2D (87 women, 21 men) and 125 (3...

    journal_title：Diabetes research and clinical practice

    pub_type： 杂志文章

    doi：10.1016/j.diabres.2017.10.020

    authors： Rosa ECCC,Dos Santos RRC,Fernandes LFA,Neves FAR,Coelho MS,Amato AA

    更新日期：2018-01-01 00:00:00

  • Measurement of cytosolic free calcium concentration in relation to insulin release in normal rat pancreatic islets.

    abstract：:The effects of glucose (16.7 mM), potassium (50 mM), forskolin (20 microM), dibutyryl cyclic AMP (1 mM) and arachidonic acid (82 microM) upon insulin release and cytosolic free calcium concentrations ([Ca2+]i) were investigated in normal rat pancreatic islets. Potassium, forskolin and dibutyryl cyclic AMP significantl...

    journal_title：Diabetes research and clinical practice

    pub_type： 杂志文章

    doi：10.1016/s0168-8227(87)80053-0

    authors： Draznin B,Metz SA,Sussman KE,Leitner JW

    更新日期：1987-09-01 00:00:00

  • Predictive value of serum NT-proBNP levels in type 2 diabetic people with diabetic nephropathy.

    abstract：OBJECTIVE:The serum N-terminal fragment of pro brain natriuretic peptide (NT-proBNP) level in type 2 diabetic subjects with or without diabetic nephropathy (DN) is still unclear. We aimed to evaluate the relationship between serum NT-proBNP levels and different stages of diabetic nephropathy, and identify probable fact...

    journal_title：Diabetes research and clinical practice

    pub_type： 杂志文章

    doi：10.1016/j.diabres.2011.09.029

    authors： Danis R,Ozmen S,Arikan S,Gokalp D,Alyan O

    更新日期：2012-03-01 00:00:00

  • Gestational diabetes mellitus among Sub-Saharan African and Surinamese women in the Netherlands.

    abstract：AIM:We assessed the association between ethnicity and the risk of gestational diabetes mellitus (GDM) in the Netherlands. METHODS:A cohort of 7815 women with known GDM status and ethnicity, including women of Sub-Saharan African ethnicity who are currently not identified as high-risk in guidelines. We compared GDM rat...

    journal_title：Diabetes research and clinical practice

    pub_type： 杂志文章

    doi：10.1016/j.diabres.2020.108367

    authors： Rademaker D,van Schaijik CI,Oostvogels AJJM,van Rijn BB,Evers I,DeVries JH,Agyemang C,Vrijkotte TGM,Painter RC

    更新日期：2020-10-01 00:00:00

  • Effects of evolving lipid-lowering drugs on carbohydrate metabolism.

    abstract：:The understanding that statins reduce but not eliminate the cardiovascular risk associated with disturbed lipid metabolism and the existence of forms of dyslipidemia that are unresponsive or only partially responsive to statins have led to the development of many novel lipid-lowering drugs. Accumulating evidence sugge...

    journal_title：Diabetes research and clinical practice

    pub_type： 杂志文章,评审

    doi：10.1016/j.diabres.2017.12.012

    authors： Tsimihodimos V,Elisaf M

    更新日期：2018-03-01 00:00:00

  • Applicability of diagnostic constructs for cognitive impairment in patients with type 2 diabetes mellitus.

    abstract：AIMS:Type 2 diabetes mellitus (T2DM) is associated with subtle cognitive changes, but also with more severe stages of cognitive dysfunction, including mild cognitive impairment (MCI) and dementia. For these severe stages, it is uncertain which domains are primarily affected and if all patients with impairment are captu...

    journal_title：Diabetes research and clinical practice

    pub_type： 杂志文章

    doi：10.1016/j.diabres.2018.05.025

    authors： Groeneveld ON,van den Berg E,Rutten GEHM,Koekkoek PS,Kappelle LJ,Biessels GJ,COG-ID study group.

    更新日期：2018-08-01 00:00:00

  • The levels of plasma growth arrest-specific protein 6 is associated with insulin sensitivity and inflammation in women.

    abstract：AIMS:Vitamin K-dependent growth arrest-specific protein 6 (Gas6) and its receptors of the TAM (TYRO-3/Axl/Mer) family are ubiquitously expressed in immune, cardiovascular, and reproductive systems. They play pivotal roles of regulating tissue homeostasis via anti-inflammatory effects. Recent studies show that the Gas6/...

    journal_title：Diabetes research and clinical practice

    pub_type： 杂志文章

    doi：10.1016/j.diabres.2013.12.057

    authors： Kuo FC,Hung YJ,Shieh YS,Hsieh CH,Hsiao FC,Lee CH

    更新日期：2014-02-01 00:00:00

  • Effect of ischemia on peripheral nerve function in diabetes mellitus.

    abstract：:In Japan, diabetic patients are known to be able to sit on the floor for a prolonged time because of mildness or absence of ischemic paresthesia. In order to investigate this resistance to ischemia quantitatively, the mixed nerve function of the median nerve was studied during 30 min of ischemia using surface electrod...

    journal_title：Diabetes research and clinical practice

    pub_type： 杂志文章

    doi：10.1016/s0168-8227(86)80004-3

    authors： Kuriya N,Mori M,Miyake S,Takamori M,Nagataki S

    更新日期：1986-09-01 00:00:00