Abstract：
:This paper compiles the beneficial effects of cocoa polyphenols on human health, especially with regard to cardiovascular and inflammatory diseases, metabolic disorders, and cancer prevention. Their antioxidant properties may be responsible for many of their pharmacological effects, including the inhibition of lipid peroxidation and the protection of LDL-cholesterol against oxidation, and increase resistance to oxidative stress. The phenolics from cocoa also modify the glycemic response and the lipid profile, decreasing platelet function and inflammation along with diastolic and systolic arterial pressures, which, taken together, may reduce the risk of cardiovascular mortality. Cocoa polyphenols can also modulate intestinal inflammation through the reduction of neutrophil infiltration and expression of different transcription factors, which leads to decreases in the production of proinflammatory enzymes and cytokines. The phenolics from cocoa may thus protect against diseases in which oxidative stress is implicated as a causal or contributing factor, such as cancer. They also have antiproliferative, antimutagenic, and chemoprotective effects, in addition to their anticariogenic effects.
journal_name
Oxid Med Cell Longevjournal_title
Oxidative medicine and cellular longevityauthors
Andújar I,Recio MC,Giner RM,Ríos JLdoi
10.1155/2012/906252subject
Has Abstractpub_date
2012-01-01 00:00:00pages
906252eissn
1942-0900issn
1942-0994journal_volume
2012pub_type
杂志文章,评审abstract：:Platelet-rich plasma (PRP) has grown as an attractive biologic instrument in regenerative medicine for its powerful healing properties. It is considered as a source of growth factors that may induce tissue repairing and improve fibrosis. This product has proven its efficacy in multiple studies, but its effect on cispl...
journal_title：Oxidative medicine and cellular longevity
pub_type： 杂志文章
doi：10.1155/2018/9658230
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journal_title：Oxidative medicine and cellular longevity
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journal_title：Oxidative medicine and cellular longevity
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doi：10.1155/2018/2109216
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journal_title：Oxidative medicine and cellular longevity
pub_type： 杂志文章
doi：10.1155/2018/5835072
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journal_title：Oxidative medicine and cellular longevity
pub_type： 杂志文章
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journal_title：Oxidative medicine and cellular longevity
pub_type： 杂志文章
doi：10.1155/2016/3939540
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journal_title：Oxidative medicine and cellular longevity
pub_type： 杂志文章
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journal_title：Oxidative medicine and cellular longevity
pub_type： 杂志文章,评审
doi：10.1155/2018/1873962
更新日期：2018-02-04 00:00:00
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journal_title：Oxidative medicine and cellular longevity
pub_type： 杂志文章,评审
doi：10.1155/2016/7095901
更新日期：2015-01-01 00:00:00
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journal_title：Oxidative medicine and cellular longevity
pub_type： 杂志文章
doi：10.1155/2018/8753063
更新日期：2018-03-21 00:00:00
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journal_title：Oxidative medicine and cellular longevity
pub_type： 杂志文章
doi：10.1155/2020/5649767
更新日期：2020-12-24 00:00:00
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journal_title：Oxidative medicine and cellular longevity
pub_type： 杂志文章
doi：10.1155/2016/5810908
更新日期：2016-01-01 00:00:00
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journal_title：Oxidative medicine and cellular longevity
pub_type： 杂志文章
doi：10.1155/2019/9141343
更新日期：2019-01-10 00:00:00
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journal_title：Oxidative medicine and cellular longevity
pub_type： 杂志文章
doi：10.1155/2018/9086747
更新日期：2018-06-25 00:00:00
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journal_title：Oxidative medicine and cellular longevity
pub_type： 杂志文章
doi：10.1155/2018/4780615
更新日期：2018-10-28 00:00:00
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journal_title：Oxidative medicine and cellular longevity
pub_type： 杂志文章
doi：10.1155/2019/1897316
更新日期：2019-03-25 00:00:00
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journal_title：Oxidative medicine and cellular longevity
pub_type： 杂志文章
doi：10.1155/2018/4740739
更新日期：2018-02-18 00:00:00
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journal_title：Oxidative medicine and cellular longevity
pub_type： 杂志文章
doi：10.1155/2020/3076131
更新日期：2020-02-27 00:00:00
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journal_title：Oxidative medicine and cellular longevity
pub_type： 杂志文章
doi：10.1155/2018/9524657
更新日期：2018-02-14 00:00:00
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journal_title：Oxidative medicine and cellular longevity
pub_type： 杂志文章,评审
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journal_title：Oxidative medicine and cellular longevity
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journal_title：Oxidative medicine and cellular longevity
pub_type： 杂志文章
doi：10.1155/2019/8218650
更新日期：2019-10-20 00:00:00
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journal_title：Oxidative medicine and cellular longevity
pub_type： 杂志文章
doi：10.1155/2015/536456
更新日期：2015-01-01 00:00:00
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journal_title：Oxidative medicine and cellular longevity
pub_type： 杂志文章
doi：10.1155/2014/639868
更新日期：2014-01-01 00:00:00
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journal_title：Oxidative medicine and cellular longevity
pub_type： 杂志文章
doi：10.1155/2015/329306
更新日期：2015-01-01 00:00:00
abstract：:As a pair of differential isomers, Kaji-ichigoside F1 and Rosamultin are both pentacyclic triterpenoids isolated from the subterranean root of Potentilla anserina L., a plant used in folk medicine in western China as antihypoxia and anti-inflammatory treatments. We demonstrated that Kaji-ichigoside F1 and Rosamultin e...
journal_title：Oxidative medicine and cellular longevity
pub_type： 杂志文章
doi：10.1155/2020/6837982
更新日期：2020-04-12 00:00:00
abstract：:Purpose. To investigate the preventive effect of resveratrol (RES) on the formation of portal vein system thrombosis (PVST) in a rat fibrosis model. Methods. A total of 64 male SD rats, weighing 200-300 g, were divided into five groups: Sham operation, Splenectomy I, Splenectomy II, RES, and low molecular weight hepar...
journal_title：Oxidative medicine and cellular longevity
pub_type： 杂志文章
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更新日期：2016-01-01 00:00:00
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journal_title：Oxidative medicine and cellular longevity
pub_type： 杂志文章
doi：10.1155/2020/3025361
更新日期：2020-04-13 00:00:00
abstract：:Oxidative stress has been proven as one of the most critical regulatory mechanisms involved in fine Particulate Matter- (PM2.5-) mediated toxicity. For a better understanding of the underlying mechanisms that enable oxidative stress to participate in PM2.5-induced toxic effects, the current study explored the effects ...
journal_title：Oxidative medicine and cellular longevity
pub_type： 杂志文章
doi：10.1155/2019/2492368
更新日期：2019-12-07 00:00:00
abstract：:Over 50% of end-stage renal disease (ESRD) patients die of cardiovascular disease. ESRD patients treated with maintenance hemodialysis are repeatedly exposed to oxidative stress. The aim of the study was to find the relationship between lifestyle factors, nutritional status, calcium-phosphate metabolism, and selected ...
journal_title：Oxidative medicine and cellular longevity
pub_type： 杂志文章
doi：10.1155/2019/6309465
更新日期：2019-09-05 00:00:00
