Red blood cell disorders in recently arrived African immigrants to Gran Canaria, Spain.

Abstract:

BACKGROUND:In the last decade immigration to Europe has increased, with Africa being the source of a large number of immigrants. In addition to infections, this group has other less known health problems, such as erythrocyte abnormalities. METHODS:The objectives of this study were: the systematic evaluation of red cell abnormalities in 200 newly arrived asymptomatic African immigrants on the Canaries; the systematic evaluation of haemoglobinopathies and their characterization in this population; and the relationship of red blood cell disorders and parasitic infections. RESULTS:Of the studied immigrants 53 (26.5%) had red cell disorders according to their CBC parameters (Hb and/or MCV). In 48 people (24.0%) one or more etiologic diagnoses were made. Specifically, in order of frequency, a total of 26 structural haemoglobinopathies, 14 α-thalassemias, 2 β-thalassemias and 14 iron deficiencies were diagnosed. There was a statistically significant association between the presence of anemia, microcytosis, structural haemoglobinopathies or α thalassemia and sub-Saharan origin. However, no statistically significant association between the abovementioned parameters and eosinophilia or helminthic infection was observed. CONCLUSIONS:These results suggest that, even in the presence of normal Hb and MCV values, including haemoglobinopathies in the initial screening of newly arrived sub-Saharan immigrants would be very useful.

authors

de-la-Iglesia-Iñigo S,Carranza-Rodriguez C,Ropero-Gradilla P,González-Fernandez FA,Molero-Labarta T,Hemmersbach-Miller M,Pérez-Arellano JL

doi

10.1093/trstmh/trs017

subject

Has Abstract

pub_date

2013-02-01 00:00:00

pages

91-7

issue

2

eissn

0035-9203

issn

1878-3503

pii

trs017

journal_volume

107

pub_type

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