Abstract：
:Human enamel has been found to be a coating with excellent mechanical performance, and has undergone extensive investigation and discussion. However, most of the reported studies consider the enamel as a homogeneous anisotropic biocomposite. The current study illustrated the graded properties of the biocomposite from its functional load-bearing direction. Within the thickness of the enamel, from the outer surface towards the enamel-dentin junction (EDJ), the elastic modulus (E(x)) and hardness (H(x)) of enamel exist in an exponential relationship with normalized thickness (x) as E(x)=111.64x(0.18) (R(2)=0.94) and H(x)=4.41x(0.16) (R(2)=0.87) GPa, respectively. Moreover, the creep ability of enamel increases towards the EDJ. The graded properties of the biocomposite can be explained by both microstructural and compositional changes along the thickness of the material towards the EDJ. Finite element analysis indicates that the graded properties of enamel have important roles in reducing the enamel-dentin interface stresses and maintaining the integrity of the multilayer tooth structure. The results provide a new angle to understand the excellent mechanical behaviour of the multilayer tooth structure and may inspire the development of new functionally graded materials and coating structures.
journal_name
Acta Biomaterjournal_title
Acta biomaterialiaauthors
He LH,Yin ZH,van Vuuren LJ,Carter EA,Liang XWdoi
10.1016/j.actbio.2012.12.029subject
Has Abstractpub_date
2013-05-01 00:00:00pages
6330-7issue
5eissn
1742-7061issn
1878-7568pii
S1742-7061(12)00628-9journal_volume
9pub_type
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journal_title：Acta biomaterialia
pub_type： 杂志文章
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更新日期：2012-02-01 00:00:00
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pub_type： 杂志文章
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更新日期：2018-12-01 00:00:00
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pub_type： 杂志文章
doi：10.1016/j.actbio.2020.11.032
更新日期：2021-02-01 00:00:00
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pub_type： 杂志文章
doi：10.1016/j.actbio.2017.11.032
更新日期：2018-01-15 00:00:00
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journal_title：Acta biomaterialia
pub_type： 杂志文章
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更新日期：2018-02-01 00:00:00
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journal_title：Acta biomaterialia
pub_type： 杂志文章
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更新日期：2017-01-15 00:00:00
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pub_type： 杂志文章
doi：10.1016/j.actbio.2016.05.006
更新日期：2016-07-15 00:00:00
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journal_title：Acta biomaterialia
pub_type： 杂志文章
doi：10.1016/j.actbio.2016.07.045
更新日期：2016-10-01 00:00:00
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journal_title：Acta biomaterialia
pub_type： 杂志文章
doi：10.1016/j.actbio.2009.09.028
更新日期：2010-04-01 00:00:00
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journal_title：Acta biomaterialia
pub_type： 杂志文章
doi：10.1016/j.actbio.2020.07.027
更新日期：2020-09-15 00:00:00
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journal_title：Acta biomaterialia
pub_type： 杂志文章
doi：10.1016/j.actbio.2017.09.033
更新日期：2017-12-01 00:00:00
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journal_title：Acta biomaterialia
pub_type： 杂志文章
doi：10.1016/j.actbio.2018.09.060
更新日期：2018-11-01 00:00:00
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journal_title：Acta biomaterialia
pub_type： 杂志文章
doi：10.1016/j.actbio.2010.06.006
更新日期：2010-11-01 00:00:00
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journal_title：Acta biomaterialia
pub_type： 杂志文章
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pub_type： 杂志文章
doi：10.1016/j.actbio.2005.06.001
更新日期：2005-09-01 00:00:00
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pub_type： 杂志文章,评审
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更新日期：2019-08-01 00:00:00
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journal_title：Acta biomaterialia
pub_type： 杂志文章
doi：10.1016/j.actbio.2013.07.008
更新日期：2013-11-01 00:00:00
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journal_title：Acta biomaterialia
pub_type： 临床试验,杂志文章
doi：10.1016/j.actbio.2007.06.009
更新日期：2008-03-01 00:00:00
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journal_title：Acta biomaterialia
pub_type： 杂志文章
doi：10.1016/j.actbio.2008.03.017
更新日期：2008-09-01 00:00:00
abstract：:Fluorescence resonance energy transfer (FRET) was employed to monitor the molecular dissociation of a chitosan/DNA complex with different molecular weights of chitosan. Chitosan with different molecular weights was complexed with plasmid DNA and the complex formation was monitored using dynamic light scattering and a ...
journal_title：Acta biomaterialia
pub_type： 杂志文章
doi：10.1016/j.actbio.2008.01.010
更新日期：2008-07-01 00:00:00
abstract：:Several studies have reported the benefits of mesenchymal stem cells (MSCs) for bone tissue engineering. However, vascularization remains one of the main obstacles that must be overcome to reconstruct large bone defects. In vitro prevascularization of the three-dimensional (3-D) constructs using co-cultures of human p...
journal_title：Acta biomaterialia
pub_type： 杂志文章
doi：10.1016/j.actbio.2013.05.025
更新日期：2013-09-01 00:00:00
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journal_title：Acta biomaterialia
pub_type： 杂志文章
doi：10.1016/j.actbio.2017.09.039
更新日期：2017-12-01 00:00:00
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journal_title：Acta biomaterialia
pub_type： 杂志文章
doi：10.1016/j.actbio.2012.05.016
更新日期：2012-09-01 00:00:00
abstract：:Slow protein release from amyloidal materials is a molecular platform used by nature to control protein hormone secretion in the endocrine system. The molecular mechanics of the sustained protein release from amyloids remains essentially unexplored. Inclusion bodies (IBs) are natural amyloids that occur as discrete pr...
journal_title：Acta biomaterialia
pub_type： 杂志文章
doi：10.1016/j.actbio.2012.11.033
更新日期：2013-04-01 00:00:00
