Autonomic regulation of preterm infants is enhanced by Family Nurture Intervention.

Abstract:

:Preterm infants have maturational delays in several neurobehavioral systems. This study assesses the impact of the Family Nurture Intervention (FNI) in the neonatal intensive care unit (NICU) on the maturation of autonomic regulation of preterm infants. Preterm infants born at 26-34 weeks postmenstrual age (PMA) were assigned to groups receiving either standard care (SC) or SC plus FNI, using a randomized controlled trial design. At two collection time points, approximately 35 weeks and 41 weeks PMA, electrocardiograms (ECG) were monitored for approximately 1 hour during sleep. Heart rate and respiratory sinus arrhythmia (RSA) were quantified from the ECG. Across the two time points, the FNI group exhibited greater increases in RSA (Cohen's d = 0.35) and slope between RSA and heart rate, as a measure of vagal efficiency (Cohen's d = 0.62). These results document that FNI resulted in enhanced autonomic regulation consistent with greater maturation of cardiac function. These and previous findings strongly suggest that facilitating early nurturing interactions and emotional connection between preterm infants and their mothers is a practicable and effective means of optimizing postnatal development in preterm infants. Interpretation of these autonomic function results also enriches our understanding of the potential long-term beneficial outcomes of FNI by drawing upon polyvagal theory, which explains how autonomic state provides a neurophysiological platform for optimal co-regulation between infant and caregiver, and by drawing upon calming cycle theory, which provides a model for understanding how repeated mother/infant calming interactions positively condition autonomic state and reinforce approach, prosocial behaviors.

journal_name

Dev Psychobiol

authors

Porges SW,Davila MI,Lewis GF,Kolacz J,Okonmah-Obazee S,Hane AA,Kwon KY,Ludwig RJ,Myers MM,Welch MG

doi

10.1002/dev.21841

subject

Has Abstract

pub_date

2019-09-01 00:00:00

pages

942-952

issue

6

eissn

0012-1630

issn

1098-2302

journal_volume

61

pub_type

杂志文章,随机对照试验
  • Effects of brief stress exposure during early postnatal development in Balb/CByJ mice: II. Altered cortical morphology.

    abstract::Early life experience can significantly determine later mental health status and cognitive function. Neonatal stress, in particular, has been linked to the etiology of mental health disorders as divergent as mood disorder, schizophrenia, and autism. Our study uses a Balb/CByJ mouse model to test the hypothesis, that n...

    journal_title:Developmental psychobiology

    pub_type: 杂志文章

    doi:10.1002/dev.21028

    authors: Hohmann CF,Beard NA,Kari-Kari P,Jarvis N,Simmons Q

    更新日期:2012-11-01 00:00:00

  • Gustatory determinants of suckling in albino rats 5-20 days of age.

    abstract::Taste reactivity in suckling rat pups was assessed. Five-day-old rats in Experiment I were equipped with tongue cannulae seated 2 mm rostral, 0-3 mm caudal, or 4-6 mm caudal to the intermolar eminence. Either water, 1.4 X 10(-3) QHC1, .50M NH4Cl, or .43M NaCl was delivered in one of three fashions during suckling: (1)...

    journal_title:Developmental psychobiology

    pub_type: 杂志文章

    doi:10.1002/dev.420180106

    authors: Kehoe P,Blass EM

    更新日期:1985-01-01 00:00:00

  • Dopamine's role in social modulation of infant isolation-induced vocalization: II. Maternally modulated infant separation responses are regulated by D1- and D2-family dopamine receptors.

    abstract::Mammalian infant behavior directed toward caregivers is critical to survival and may play a role in establishing social bonds. Most mammalian infants vocalize when isolated. Rat pups vocalize at a higher rate when isolated following an interaction with an adult female than after an interaction with littermates, a phen...

    journal_title:Developmental psychobiology

    pub_type: 杂志文章

    doi:10.1002/dev.20355

    authors: Muller JM,Moore H,Myers MM,Shair HN

    更新日期:2009-03-01 00:00:00

  • Mere odor exposure learning in the rat neonate immediately after birth and 1 day later.

    abstract::Rat pups are more resistant to retroactive associative interference 3 hr after birth than 24 hr later [Cheslock et al. [2004] Developmental Science, 7, 581-598]. The present experiments tested the effect of age, retention interval and dam presence during the retention interval on odor-induced motor activity subsequent...

    journal_title:Developmental psychobiology

    pub_type: 杂志文章

    doi:10.1002/dev.20456

    authors: Miller SS,Spear NE

    更新日期:2010-05-01 00:00:00

  • Behavioral development in three hamster species.

    abstract::The preweaning behavioral development was compared in 3 hamster species: the golden (Mesocricetus auratus), Chinese (Cricetulus griseus), and Djungarian (Phodopus sungorus). Differences in the age of appearance of action patterns could not be summarized by simply ranking species on either precocity or developmental sp...

    journal_title:Developmental psychobiology

    pub_type: 杂志文章

    doi:10.1002/dev.420090404

    authors: Daly M

    更新日期:1976-07-01 00:00:00

  • Maltreatment exposure across childhood and low-grade inflammation: Considerations of exposure type, timing, and sex differences.

    abstract::Links between child maltreatment and low-grade inflammation in adulthood are well documented, but these studies often rely on adults to report retrospectively on experiences of childhood abuse. Furthermore, these findings raise questions about whether exposure to childhood maltreatment needs time to "incubate," only g...

    journal_title:Developmental psychobiology

    pub_type: 杂志文章

    doi:10.1002/dev.22031

    authors: Ehrlich KB,Miller GE,Rogosch FA,Cicchetti D

    更新日期:2020-09-08 00:00:00

  • Lateral preferences in children with intellectual deficiency of idiopathic origin.

    abstract::The goal of this study was to evaluate lateral preferences in a population of children with intellectual deficiency of idiopathic origin, compared with those of typically developing (TD) children. Two groups of children with mild or moderate intellectual deficiency were observed. Handedness (using a 10-item test and B...

    journal_title:Developmental psychobiology

    pub_type: 杂志文章

    doi:10.1002/dev.20167

    authors: Leconte P,Fagard J

    更新日期:2006-09-01 00:00:00

  • Autonomic regulation in fragile X syndrome.

    abstract::Autonomic reactivity was studied in individuals with fragile X syndrome (FXS), a genetic disorder partially characterized by abnormal social behavior. Relative to age-matched controls, the FXS group had faster baseline heart rate and lower amplitude respiratory sinus arrhythmia (RSA). In contrast to the typically deve...

    journal_title:Developmental psychobiology

    pub_type: 杂志文章

    doi:10.1002/dev.20551

    authors: Heilman KJ,Harden ER,Zageris DM,Berry-Kravis E,Porges SW

    更新日期:2011-12-01 00:00:00

  • Conditioned changes in ultrasonic vocalizations to an aversive olfactory stimulus are lateralized in 6-day-old rats.

    abstract::Using a soft rubber plug to block airflow in one naris, Kucharski, Johanson, and Hall (1986) found that some forms of olfactory memory (e.g., odor preferences) were lateralized in young rats while other forms (e.g., conditioned activation and mouthing) were not. The present experiments extended that research by showin...

    journal_title:Developmental psychobiology

    pub_type: 杂志文章

    doi:10.1002/1098-2302(200011)37:3<121::aid-dev1>3.0.co

    authors: Weber M,Paxinos G,Richardson R

    更新日期:2000-11-01 00:00:00

  • Moderate early life stress improves adult zebrafish (Danio rerio) working memory but does not affect social and anxiety-like responses.

    abstract::Early life stress (ELS) is defined as a short or chronic period of trauma, environmental or social deprivation, which can affect different neurochemical and behavioral patterns during adulthood. Zebrafish (Danio rerio) have been widely used as a model system to understand human neurodevelopmental disorders and display...

    journal_title:Developmental psychobiology

    pub_type: 杂志文章

    doi:10.1002/dev.21986

    authors: Fontana BD,Gibbon AJ,Cleal M,Sudwarts A,Pritchett D,Miletto Petrazzini ME,Brennan CH,Parker MO

    更新日期:2021-01-01 00:00:00

  • Early ontogeny of face grooming in mice.

    abstract::A U-shaped function of behavioral growth characterizes the early ontogeny of face grooming in mice. In the first few postnatal days (0-100 hr), mice groom their face by using temporally isolated strokes, or bouts of strokes, which vary in amplitude and symmetry. Later on (100-200 hr), bouts disappear, asymmetry is eli...

    journal_title:Developmental psychobiology

    pub_type: 杂志文章

    doi:10.1002/dev.420180609

    authors: Golani I,Fentress JC

    更新日期:1985-11-01 00:00:00

  • Cross-sectional analysis of the association between age and corpus callosum size in chimpanzees (Pan troglodytes).

    abstract::The CC is the major white matter tract connecting the cerebral hemispheres and provides for interhemispheric integration of sensory, motor and higher-order cognitive information. The midsagittal area of the CC has been frequently used as a marker of brain development in humans. We report the first investigation into t...

    journal_title:Developmental psychobiology

    pub_type: 杂志文章

    doi:10.1002/dev.20421

    authors: Hopkins WD,Phillips KA

    更新日期:2010-03-01 00:00:00

  • Relationship between age and activity varies by sex in titi monkeys (Callicebus cupreus).

    abstract::Motor activity increases during development and typically peaks before reproductive maturity. Males may become more active than do females, and this sex difference in activity may be a mechanism contributing to sex-biased dispersal. The generality of the link between sex differences in activity and sex differences in ...

    journal_title:Developmental psychobiology

    pub_type: 杂志文章

    doi:10.1002/dev.20286

    authors: Mayeaux DJ

    更新日期:2008-04-01 00:00:00

  • The inhibition of automatic saccades in early infancy.

    abstract::Adult patients with damage centered around the frontal eye fields are severely impaired in the ability to suppress unwanted automatic saccades and in the ability to make volitional eye movements. Over the first few weeks of life most saccades generated by infants appear to be automatic, and are triggered in response t...

    journal_title:Developmental psychobiology

    pub_type: 杂志文章

    doi:10.1002/dev.420280504

    authors: Johnson MH

    更新日期:1995-07-01 00:00:00

  • Developmental differences in the analgesia produced by the central cholinergic system.

    abstract::In order to study the ontogenesis of cholinergically mediated analgesia in the central nervous system (CNS), 10-day-, 28-day-, and 3-month-old rats were injected with .025, .05, and .10 mg/kg of oxotremorine, a muscarinic receptor agonist. To restrict the effect of oxotremorine to the CNS, methylscopolamine, a periphe...

    journal_title:Developmental psychobiology

    pub_type: 杂志文章

    doi:10.1002/dev.420200311

    authors: Hamm RJ,Knisely JS

    更新日期:1987-05-01 00:00:00

  • The association between prenatal alcohol consumption and preschool child stress system disturbance.

    abstract:BACKGROUND:Drinking alcohol during pregnancy is considered a risk factor for child development; however, child biomarkers of prenatal alcohol exposure have been rarely studied. We examined whether a meconium alcohol metabolite (ethyl glucuronide, EtG) was associated with child cortisol concentrations at primary school ...

    journal_title:Developmental psychobiology

    pub_type: 杂志文章

    doi:10.1002/dev.22038

    authors: Grimm J,Stemmler M,Golub Y,Schwenke E,Goecke TW,Fasching PA,Beckmann MW,Kratz O,Moll GH,Kornhuber J,Eichler A

    更新日期:2020-10-03 00:00:00

  • Do temperamentally shy children process emotion differently than nonshy children? Behavioral, psychophysiological, and gender differences in reticent preschoolers.

    abstract::We examined regional brain electrical activity (EEG), heart rate, and subjective responses at rest and during the presentation of videoclips designed to elicit a range of emotions (e.g., sadness, anger, happiness, fear) among a sample of healthy 4-year-old children selected for temperamental shyness. We found that shy...

    journal_title:Developmental psychobiology

    pub_type: 杂志文章

    doi:10.1002/dev.20133

    authors: Theall-Honey LA,Schmidt LA

    更新日期:2006-04-01 00:00:00

  • Sitting skill and the emergence of arms-free sitting affects the frequency of object looking and exploration.

    abstract::The development of sitting changes how much infants are able to explore objects. Infants who can sit with their arms free are likely to explore their environment more effectively than prop sitters, as their hands are free to explore. We sought to quantify how prop sitters differed in the amount of visual and manual ex...

    journal_title:Developmental psychobiology

    pub_type: 杂志文章

    doi:10.1002/dev.21854

    authors: Marcinowski EC,Tripathi T,Hsu LY,Westcott McCoy S,Dusing SC

    更新日期:2019-11-01 00:00:00

  • Complete maternal deprivation affects social, but not spatial, learning in adult rats.

    abstract::The effects of maternal deprivation on learning of social and spatial tasks were investigated in female adult rats. Pups were reared artificially and received "lickinglike" tactile stimulation (AR animals) or were reared with their mothers (MR animals). In adulthood, subjects were tested on paradigms of spatial learni...

    journal_title:Developmental psychobiology

    pub_type: 杂志文章

    doi:10.1002/dev.10131

    authors: Lévy F,Melo AI,Galef BG Jr,Madden M,Fleming AS

    更新日期:2003-11-01 00:00:00

  • Maternal emotion dysregulation, parenting stress, and child physiological anxiety during dark-enhanced startle.

    abstract::Maternal emotion dysregulation (ED) plays a crucial role in the development of psychopathology in children. The current study aimed to investigate parenting stress as a mediator of the relationship between maternal emotion dysregulation and child startle potentiation, with child sex as a moderator. Mothers were interv...

    journal_title:Developmental psychobiology

    pub_type: 杂志文章

    doi:10.1002/dev.21574

    authors: Cao M,Powers A,Cross D,Bradley B,Jovanovic T

    更新日期:2017-12-01 00:00:00

  • Early handling influences on behavioral and physiological responses during active avoidance.

    abstract::The effects of early handling on behavioral and physiological responses of the rat during active avoidance learning were investigated. Handled and nonhandled males and females were run in a 2-way shuttlebox task with an unconditioned stimulus of either .5 mA or .8 mA. Animals exposed to .8 mA showed a higher corticost...

    journal_title:Developmental psychobiology

    pub_type: 杂志文章

    doi:10.1002/dev.420100209

    authors: Weinberg J,Levine S

    更新日期:1977-03-01 00:00:00

  • Striking absence of long-lasting effects of early color deprivation on monkey vision.

    abstract::A monkey (Macaca fascicularis) spent its first three months under far red illumination that made color vision impossible. It developed normal spectral sensitivity. In the present study we examined two aspects of color vision that presumably reflect cortical connectivity. In the first part of this article we show that ...

    journal_title:Developmental psychobiology

    pub_type: 杂志文章

    doi:10.1002/dev.420230506

    authors: Brenner E,Cornelissen F,Nuboer W

    更新日期:1990-07-01 00:00:00

  • The manifestation of infant hand-use preferences when reaching for objects during the seven--to thirteen-month age period.

    abstract::Handedness is an aspect of hemispheric specialization whose pattern of expression may signal an unusual specialization that in turn, may underlie several developmental psychopathologies. It is generally believed that infant handedness is neither stable nor reliable and hence, cannot be used as an early marker of poten...

    journal_title:Developmental psychobiology

    pub_type: 杂志文章

    doi:10.1002/dev.20161

    authors: Michel GF,Tyler AN,Ferre C,Sheu CF

    更新日期:2006-09-01 00:00:00

  • The association between mothers' and daughters' positive affect is moderated by child cardiac vagal regulation.

    abstract:INTRODUCTION:Extensive research has supported the importance of children's positive affect in fostering prosperous psychosocial adjustment. Children's positive affect is believed to be significantly shaped by their environment in general and their caregivers' positive affect in particular. The current study investigate...

    journal_title:Developmental psychobiology

    pub_type: 杂志文章

    doi:10.1002/dev.21939

    authors: Rousseau S,Kritzman L,Frenkel TI,Levit-Binnun N,Golland Y

    更新日期:2020-09-01 00:00:00

  • Sensitive periods for language and recovery from stroke: conceptual and practical parallels.

    abstract::In this review, we consider the literature on sensitive periods for language acquisition from the perspective of the stroke recovery literature treated in this Special Issue. Conceptually, the two areas of study are linked in a number of ways. For example, the fact that learning itself can set the stage for future fai...

    journal_title:Developmental psychobiology

    pub_type: 杂志文章,评审

    doi:10.1002/dev.20626

    authors: Zevin JD,Datta H,Skipper JI

    更新日期:2012-04-01 00:00:00

  • Neonatal 6-OHDA lesions and rearing in complex environments: regional effects on adult brain 14C-2-deoxyglucose uptake revealed by exposure to novel stimulation.

    abstract::Behavioral and neuromorphological data have suggested at least a partial interaction between the effects of norepinephrine-depleting neonatal 6-OHDA lesions and the effects of rearing in enriched environments. The present study examined the impact of both of these early manipulations upon regional brain uptake of 14C-...

    journal_title:Developmental psychobiology

    pub_type: 杂志文章

    doi:10.1002/dev.420250304

    authors: Nobrega JN,Saari MJ,Armstrong JN,Reed T

    更新日期:1992-04-01 00:00:00

  • First time experiences in infancy: when they appear to be pleasant, do they activate the adrenocortical stress response?

    abstract::The effect of a positive first-time experience on adrenocortical activity was examined in 48 6- to 13-month-old infants who took part in two sessions of a YMCA-like mother-infant swim class. Experience was manipulated by comparing Novice swimmers with infants who previously had taken a swim class, and by examining res...

    journal_title:Developmental psychobiology

    pub_type: 杂志文章

    doi:10.1002/dev.420250503

    authors: Hertsgaard L,Gunnar M,Larson M,Brodersen L,Lehman H

    更新日期:1992-07-01 00:00:00

  • Associative processes in differentially reared monkeys (Macaca mulatta): sensory preconditioning.

    abstract::Past research has indicated that with regard to performance in formal learning test situations, early socially isolated rhesus monkeys display atypical reactions to noxious stimuli, deficits in response inhibition, slower adaptation to reinforcement contingencies, and lower performance on oddity tasks. Twelve adult rh...

    journal_title:Developmental psychobiology

    pub_type: 杂志文章

    doi:10.1002/dev.420210406

    authors: Beauchamp AJ,Gluck JP

    更新日期:1988-05-01 00:00:00

  • Social play with an unfamiliar group in weanling rats (Rattus norvegicus).

    abstract::Early signs of aggressive behavior toward an intruder were examined in Sprague-Dawley rats. The interactions between groups of four 24-day-old pups (2 males, 2 females) and an unfamiliar male pup from another litter were observed. Some patterns of social play were asymmetric. Compared to the playmate from the group, t...

    journal_title:Developmental psychobiology

    pub_type: 杂志文章

    doi:10.1002/(sici)1098-2302(199703)30:2<165::aid-dev7>

    authors: Kahana A,Rozin A,Weller A

    更新日期:1997-03-01 00:00:00

  • Uterine positions and schedules of urination: correlates of differential maternal anogenital stimulation.

    abstract::Lactating Mongolian gerbils, like lactating Norway rats, reliably lick some pups in their litters more than they lick others. Male gerbil pups are licked more by their dams than are their sisters and some males and some females within each litter are licked more often than are their sibs of the same sex. In the presen...

    journal_title:Developmental psychobiology

    pub_type: 杂志文章

    doi:10.1002/dev.420220406

    authors: Clark MM,Bone S,Galef BG Jr

    更新日期:1989-05-01 00:00:00