Autologous intestinal reconstruction: a single institution study of the serial transverse enteroplasty (STEP) and the longitudinal intestinal lengthening and tailoring (LILT).

Abstract:

PURPOSE:To review the effectiveness of the longitudinal intestinal lengthening and tailoring (LILT) and serial transverse enteroplasty (STEP) operations in a cohort of patients with short bowel syndrome (SBS). METHODS:We conducted a retrospective analysis of children with SBS treated at our institution from 2004 until 2014. Children aged 0 days to 18 years with SBS who underwent autologous intestinal reconstruction were included in the study. RESULTS:Twenty-two SBS patients underwent 31 different lengthening procedures (LP). Seventeen patients underwent their primary lengthening procedures at our institution: 9 (53%) patients underwent a LILT, 7 (41%) underwent a STEP and 1 (6%) had a simultaneous LILT and STEP procedure. 12/22 patients had a second STEP, two had a third STEP and one patient had an intestinal transplantation after the LP. Median intestinal length at the time of surgery was 25 cm (range 12-90 cm). There was no difference in gain of intestinal length after LILT vs. STEP (p = 0.74). Length of stay and initiation of feeds were similar. Serum albumin increased after autologous bowel lengthening (p < 0.001). 50% were weaned off parenteral nutrition (PN) (5/9 of the LILT, 1/7 of the STEP, 1/1 of the combined LILT/STEP). There were no surgical complications or deaths. CONCLUSION:In patients with SBS, LILT and STEP procedures are effective for autologous intestinal reconstruction and enable intestinal rehabilitation.

journal_name

Pediatr Surg Int

authors

Shah AA,Petrosyan M,Franklin AL,Chahine AA,Torres C,Sandler AD

doi

10.1007/s00383-019-04468-3

subject

Has Abstract

pub_date

2019-06-01 00:00:00

pages

649-655

issue

6

eissn

0179-0358

issn

1437-9813

pii

10.1007/s00383-019-04468-3

journal_volume

35

pub_type

杂志文章
  • Transverse testicular ectopia: report of three cases.

    abstract::Two patients who presented with a history of right inguinal hernia and a third with an impalpable left testis were found to have transverse testicular ectopia. Both testes were fixed in their own scrotum, through a modified Ombredanne operation in two patients and a subdartos pouch in one. ...

    journal_title:Pediatric surgery international

    pub_type: 杂志文章

    doi:

    authors: Al-Samarrai AY,Al-Bassam AR,Al-Wattar Q

    更新日期:1997-02-01 00:00:00

  • Delayed diagnosis of imperforate anus: an unacceptable morbidity.

    abstract:PURPOSE:Diagnosis of imperforate anus is usually made shortly after birth with physical examination. Nonetheless, a significant number of patients have presented beyond the neonatal period without recognition of anorectal malformation. We reviewed our experience of anorectal malformations, with particular emphasis on t...

    journal_title:Pediatric surgery international

    pub_type: 杂志文章

    doi:10.1007/s00383-010-2691-5

    authors: Turowski C,Dingemann J,Gillick J

    更新日期:2010-11-01 00:00:00

  • Postoperative abdominal evisceration in children: possible risk factors.

    abstract::Postoperative abdominal evisceration may lead to high morbidity and mortality. The purpose of the present study was to determine possible risk factors, morbidity and mortality associated with abdominal evisceration in children. A total of 3,591 children underwent abdominal exploration in our clinic between 1983 and 20...

    journal_title:Pediatric surgery international

    pub_type: 杂志文章

    doi:10.1007/s00383-006-1722-8

    authors: Ciğdem MK,Onen A,Otçu S,Duran H

    更新日期:2006-08-01 00:00:00

  • Minimal invasive lung support via umbilical vein with a double-lumen cannula in a neonatal lamb model: a proof of principle.

    abstract:PURPOSE:Acute respiratory distress syndrome, with the need for invasive mechanical ventilation (MV) remains a major cause of neonatal mortality and morbidity. Although venovenous extracorporeal lung support (VV-ECLS) has become a standard of care procedure in neonatal patients with acute pulmonary failure there are no ...

    journal_title:Pediatric surgery international

    pub_type: 杂志文章

    doi:10.1007/s00383-015-3815-8

    authors: Schmidt F,Kuebler J,Ganter M,Jack T,Meschenmoser L,Sasse M,Boehne M,Bertram H,Beerbaum P,Koeditz H

    更新日期:2016-01-01 00:00:00

  • Primary anastomosis or ostomy in necrotizing enterocolitis?

    abstract::In neonates requiring operation for necrotizing enterocolitis (NEC), the complications due to enterostomy (ES) and the need for another operation to restore continuity have prompted several surgeons to employ primary anastomosis (PA) after resection as the operative strategy of choice. Our objective was to compare pri...

    journal_title:Pediatric surgery international

    pub_type: 杂志文章,评审

    doi:10.1007/s00383-017-4126-z

    authors: Haricharan RN,Gallimore JP,Nasr A

    更新日期:2017-11-01 00:00:00

  • Bladder injuries following inguinal canal surgery in infants.

    abstract:PURPOSE:Surgery of the inguinal canal is very common in infancy. Occasionally, injury of the bladder may occur with severe consequences. The aim of this paper was to warn young surgeons of this serious complication. METHODS:During the last 2 years, we observed four cases of bladder injury following surgery on inguinal...

    journal_title:Pediatric surgery international

    pub_type: 杂志文章

    doi:10.1007/s00383-010-2707-1

    authors: Aloi IP,Lais A,Caione P

    更新日期:2010-12-01 00:00:00

  • Oral administration of eicosapentaenoic acid suppresses liver fibrosis in postoperative patients with biliary atresia.

    abstract:PURPOSE:Biliary atresia (BA) is characterized by progressive inflammation of the biliary system. This inflammation persists and causes liver fibrosis, although jaundice disappears after Kasai portoenterostomy (KP). We aimed to confirm whether the oral administration of eicosapentaenoic acid (EPA) suppresses liver fibro...

    journal_title:Pediatric surgery international

    pub_type: 杂志文章

    doi:10.1007/s00383-018-4313-6

    authors: Sumida W,Uchida H,Tainaka T,Shirota C,Hinoki A,Kato T,Yokota K,Oshima K,Shirotuki R,Chiba K,Tanaka Y

    更新日期:2018-10-01 00:00:00

  • HsMAD2 mRNA expression may be a predictor of sensitivity to paclitaxel and survival in neuroblastoma.

    abstract:PURPOSE:We investigated the associations between hsMAD2 mRNA expression in tumor cells and sensitivity to paclitaxel or patient prognosis in neuroblastoma. METHODS:Fifty-one formalin-fixed paraffin-embedded tumor samples were manually microdissected to collect tumor cells, and RNA was purified. Nineteen clinical sampl...

    journal_title:Pediatric surgery international

    pub_type: 杂志文章

    doi:10.1007/s00383-010-2780-5

    authors: Otake K,Uchida K,Tanaka K,Koike Y,Inoue M,Matsushita K,Ueeda M,Hashimoto K,Kitajima T,Komada Y,Kusunoki M

    更新日期:2011-02-01 00:00:00

  • Surgical jejunostomy and radiological gastro-jejunostomy tube feeding in children: risks, benefits and nutritional outcomes.

    abstract:PURPOSE:Radiologically inserted gastrojejunal tubes (RGJ) and surgical jejunostomy (SJ) are established modes of jejunal feeding. The aim of the study is to review nutritional outcomes, complications and the practical consideration to enable patients and carers to make informed choice. METHODS:Retrospective review of ...

    journal_title:Pediatric surgery international

    pub_type: 杂志文章

    doi:10.1007/s00383-018-4303-8

    authors: Singh RR,Eaton S,Roebuck DJ,Barnacle AM,Chippington S,Cross KMK,De Coppi P,Curry JI

    更新日期:2018-09-01 00:00:00

  • Sacrococcygeal teratoma: late recurrence warrants long-term surveillance.

    abstract:BACKGROUND:Sacrococcygeal teratoma (SCT) is a rare childhood malignancy. Although overall survival is favorable, recurrent tumors are associated with poor outcomes. As most recurrences occur within 3 years of presentation, the utility of long-term surveillance is uncertain. METHODS:Patients with SCTs evaluated and man...

    journal_title:Pediatric surgery international

    pub_type: 杂志文章

    doi:10.1007/s00383-017-4132-1

    authors: Padilla BE,Vu L,Lee H,MacKenzie T,Bratton B,O'Day M,Derderian S

    更新日期:2017-11-01 00:00:00

  • Introduction of resection of intrahepatic bile duct stenosis-causing membrane or septum into laparoscopic choledochal cyst excision.

    abstract:PURPOSE:We previously showed that meticulous probing and resection of the intrahepatic bile duct stenosis (IHBDS)-causing membrane or septum was effective in preventing hepatolithiasis after choledochal cyst excisions in open surgeries. Then, we introduced this maneuver into laparoscopic choledochal cyst excisions in 2...

    journal_title:Pediatric surgery international

    pub_type: 杂志文章

    doi:10.1007/s00383-018-4320-7

    authors: Tanaka Y,Tainaka T,Sumida W,Hinoki A,Shirota C,Murase N,Oshima K,Shirotsuki R,Chiba K,Uchida H

    更新日期:2018-10-01 00:00:00

  • Isolated bowel segment created by omentoenteropexy: histologic findings.

    abstract::An isolated bowel segment (IBS) is a viable loop of bowel that is completely free of its mesenteric attachments. In this study, omentoenteropexy (OEP) was performed in 5-cm-long IBS of rats in order to provide neovascularization. Thirty-two rats were divided into four groups. After OEP, mesenteric division of the IBSs...

    journal_title:Pediatric surgery international

    pub_type: 杂志文章

    doi:10.1007/BF01076940

    authors: Günel E,Tavll L,CaGlayan F,GündoGan AH

    更新日期:1997-07-01 00:00:00

  • Spinal anesthesia for inguinal hernia repair in infants: a feasible and safe method even in emergency cases.

    abstract:BACKGROUND:Inguinal hernia repair is the most frequently performed surgical procedure in infants and children. Especially in premature infants, prevalence reaches up to 30% in coincidence with high rates of incarceration during the first year of life. These infants carry an increased risk of complications due to genera...

    journal_title:Pediatric surgery international

    pub_type: 杂志文章

    doi:10.1007/s00383-014-3590-y

    authors: Lambertz A,Schälte G,Winter J,Röth A,Busch D,Ulmer TF,Steinau G,Neumann UP,Klink CD

    更新日期:2014-10-01 00:00:00

  • Induction of angiogenic and inflammation-associated dermal biomarkers following acute UVB exposure on bio-engineered pigmented dermo-epidermal skin substitutes in vivo.

    abstract:PURPOSE:Ultraviolet (UV) radiation adversely affects skin health at cellular and molecular levels. Hence, UV radiation can directly induce inflammatory responses in the dermis by inducing erythema, edema, inflammation, dermal fibroblasts alterations, and extracellular matrix modifications. METHODS:Human keratinocytes,...

    journal_title:Pediatric surgery international

    pub_type: 杂志文章

    doi:10.1007/s00383-018-4384-4

    authors: Micka-Michalak K,Biedermann T,Reichmann E,Meuli M,Klar AS

    更新日期:2019-01-01 00:00:00

  • Is fecal diversion necessary during ileal pouch creation after initial subtotal colectomy in pediatric ulcerative colitis?

    abstract:BACKGROUND:Pediatric patients with medically refractory ulcerative colitis (UC) often undergo an initial subtotal colectomy end ileostomy (STC-I). The role of fecal diversion in the subsequent completion proctectomy/ileal-pouch anal anastomosis (CP-IPAA) remains controversial. METHODS:A multi-institutional retrospecti...

    journal_title:Pediatric surgery international

    pub_type: 杂志文章,多中心研究

    doi:10.1007/s00383-019-04440-1

    authors: Chen YJ,Grant R,Lindholm E,Lipskar A,Dolgin S,Khaitov S,Greenstein A

    更新日期:2019-04-01 00:00:00

  • Anorectal anomalies: anorectal manometric function and anal endosonography in relation to functional outcome.

    abstract::To assess the relation between continence and the manometric and endosonographic state of the anorectal segment after surgery for anorectal anomalies (ARA), 33 adolescents operated upon for ARA and 14 controls were examined. Seventeen patients had low and 16 intermediate or high ARA. Fecal continence was recorded, and...

    journal_title:Pediatric surgery international

    pub_type: 杂志文章

    doi:10.1007/BF01258715

    authors: Emblem R,Diseth T,Morkrid L

    更新日期:1997-09-01 00:00:00

  • Primary omental torsion in children: ten-year experience.

    abstract::Primary omental torsion (POT), is a rare cause of acute abdomen commonly affecting obese male adults, whereas it is extremely rare in children. In this retrospective study, we present our experience regarding the management of five children with POT and discuss the diagnostic and therapeutic implications of this entit...

    journal_title:Pediatric surgery international

    pub_type: 杂志文章

    doi:10.1007/s00383-007-1961-3

    authors: Mavridis G,Livaditi E,Baltogiannis N,Vasiliadou E,Christopoulos-Geroulanos G

    更新日期:2007-09-01 00:00:00

  • The impact of Down's syndrome on the immediate and long-term outcomes of children with Hirschsprung's disease.

    abstract::Hirschsprung's disease (HD) in Down's syndrome (DS) patients is stated to have a worse outcome than HD alone. In our study we reviewed the immediate and long-term outcomes of these children and questioned whether DS should influence the operative management. Data were collected on all children with HD (including total...

    journal_title:Pediatric surgery international

    pub_type: 杂志文章

    doi:10.1007/s00383-005-1617-0

    authors: Morabito A,Lall A,Gull S,Mohee A,Bianchi A

    更新日期:2006-02-01 00:00:00

  • An in vitro study of silicone migration from intravenous fluid tubing.

    abstract::Migration of particulate matter from plastic tubing and solid plastic implants has been documented in a number of studies, including some with the use of cardiac bypass, haemodialysis, and pump-assisted intravenous infusions. In order to ascertain whether silicone embolisation occurs when children have an Ivac 560 pum...

    journal_title:Pediatric surgery international

    pub_type: 杂志文章

    doi:10.1007/BF01194802

    authors: Dewan PA,Owen AJ,Ashwood PJ,Terlet J,Byard RW

    更新日期:1997-01-01 00:00:00

  • T-cryptantigen (TCA) activation in surgical neonates: a hidden problem.

    abstract::The Thomsen-Friedenreich cryptantigen (TCA) is located on the surface of all red cells, but is concealed by a layer of neuraminic acid. When bacteria that produce neuraminidase disrupt this coating, the TCA can be exposed and activated. If blood products containing antibody to the TCA are subsequently administered, ha...

    journal_title:Pediatric surgery international

    pub_type: 杂志文章

    doi:10.1007/s003830050488

    authors: Grant HW,Hadley GP,Adhikari M,Fernandes-Costa F

    更新日期:1998-12-01 00:00:00

  • New insights into the pathogenesis of Hirschsprung's associated enterocolitis.

    abstract::The management of Hirschsprung's disease (HD) has made dramatic strides over the last 20 years. Research into the embryological development and migration of ganglion cell has enabled a greater understanding of the pathogenesis of the disease. Coupled with new techniques in surgery, such as laparoscopy-assisted pull-th...

    journal_title:Pediatric surgery international

    pub_type: 杂志文章,评审

    doi:10.1007/s00383-005-1551-1

    authors: Murphy F,Puri P

    更新日期:2005-10-01 00:00:00

  • Minimally invasive surgery does not improve the outcome in a model of retroperitoneal murine neuroblastoma.

    abstract::Minimally invasive surgery (MIS) for cancer patients has become widely accepted in general surgery, however, it has not completely replaced the standard open operative procedures in pediatric oncology. The aim of this study was to evaluate the host relationship following MIS in a murine model of retroperitoneal neurob...

    journal_title:Pediatric surgery international

    pub_type: 杂志文章

    doi:10.1007/s003830050271

    authors: Iwanaka T,Arya G,Ziegler MM

    更新日期:1998-03-01 00:00:00

  • Oesophageal atresia is correctable and survivable in infants less than 1 kg.

    abstract:INTRODUCTION:Management of oesophageal atresia (OA) and trachea-oesophageal fistula (TOF) in babies of low birth weight is challenging especially when associated with other anomalies. Birth weight of <1500 g has previously formed part of a classification system designed to predict outcome, alongside the cardiac status ...

    journal_title:Pediatric surgery international

    pub_type: 杂志文章

    doi:10.1007/s00383-015-3851-4

    authors: Hannon EJ,Billington J,Kiely EM,Pierro A,Spitz L,Cross K,Curry JI,De Coppi P

    更新日期:2016-06-01 00:00:00

  • Comparison of diagnostic imaging modalities for the evaluation of pancreatic duct injury in children: a multi-institutional analysis from the Pancreatic Trauma Study Group.

    abstract:PURPOSE:Determining the integrity of the pancreatic duct is important in high-grade pancreatic trauma to guide decision making for operative vs non-operative management. Computed tomography (CT) is generally an inadequate study for this purpose, and magnetic resonance cholangiopancreatography (MRCP) is sometimes obtain...

    journal_title:Pediatric surgery international

    pub_type: 杂志文章,多中心研究

    doi:10.1007/s00383-018-4309-2

    authors: Rosenfeld EH,Vogel A,Russell RT,Maizlin I,Klinkner DB,Polites S,Gaines B,Leeper C,Anthony S,Waddell M,St Peter S,Juang D,Thakkar R,Drews J,Behrens B,Jafri M,Burd RS,Beaudin M,Carmant L,Falcone RA Jr,Moody S,Naik

    更新日期:2018-09-01 00:00:00

  • Clinical characteristics and prognosis of adrenocortical tumors in children.

    abstract:PURPOSE:The purpose of this study was to review the clinical characteristics and prognosis of children with adrenocortical tumors (ACT). METHODS:We retrospectively reviewed the medical records of 28 patients with ACT at our hospital between March 2010 and March 2017. RESULTS:The main clinical presentations were sexua...

    journal_title:Pediatric surgery international

    pub_type: 杂志文章

    doi:10.1007/s00383-018-4409-z

    authors: Wang Z,Liu G,Sun H,Li K,Dong K,Ma Y,Zheng S

    更新日期:2019-03-01 00:00:00

  • Testicular atrophy following inguinal hernia repair in children.

    abstract:PURPOSE:We sought to determine the incidence and timing of testicular atrophy following inguinal hernia repair in children. METHODS:We used the TRICARE database, which tracks care delivered to active and retired members of the US Armed Forces and their dependents, including > 3 million children. We abstracted data on ...

    journal_title:Pediatric surgery international

    pub_type: 杂志文章

    doi:10.1007/s00383-018-4255-z

    authors: Sonderman KA,Wolf LL,Armstrong LB,Taylor K,Jiang W,Weil BR,Koehlmoos TP,Ricca RL,Weldon CB,Haider AH,Rice-Townsend SE

    更新日期:2018-05-01 00:00:00

  • Bone marrow mononuclear stem cell infusion improves biochemical parameters and scintigraphy in infants with biliary atresia.

    abstract:PURPOSE:To evaluate early postoperative results in a case controlled study following clinical use of stem cells in extrahepatic biliary atresia (EHBA). METHODS:From July 2005 to March 2008, 30 cases of suspected EHBA were divided in two groups in an intervention study. Group A received autologous mononuclear bone marr...

    journal_title:Pediatric surgery international

    pub_type: 杂志文章

    doi:10.1007/s00383-010-2712-4

    authors: Sharma S,Kumar L,Mohanty S,Kumar R,Datta Gupta S,Gupta DK

    更新日期:2011-01-01 00:00:00

  • Is hernial sac removal necessary? Retrospective evaluation of eight patients with Morgagni hernia in 5 years.

    abstract::Eight children with Morgagni hernia were operated between January 2000 and May 2005. Medical records of the patients were evaluated retrospectively. Ages of the patients were between 3.5 months and 9 years. The diaphragmatic defect was on the right in all patients except one. One patient had bilateral diapragmatic her...

    journal_title:Pediatric surgery international

    pub_type: 杂志文章

    doi:10.1007/s00383-006-1750-4

    authors: Akbiyik F,Tiryaki TH,Senel E,Mambet E,Livanelioğlu Z,Atayurt H

    更新日期:2006-10-01 00:00:00

  • Glicentin inhibits internalization of enteric bacteria by cultured INT-407 enterocytes.

    abstract::Glicentin, the main component of enteroglucagon, has trophic effects on intestinal mucosa. It may also have an inhibitory effect on extraintestinal invasion of enteric bacteria. We have established an in vitro bioassay system for determining the effects of recombinant human glicentin on bacterial internalization by co...

    journal_title:Pediatric surgery international

    pub_type: 杂志文章

    doi:10.1007/s00383-007-1895-9

    authors: Chiba M,Sanada Y,Kawano S,Murofushi M,Okada I,Yoshizawa Y,Gomi A,Yatsuzuka M,Toki A,Hirai Y

    更新日期:2007-06-01 00:00:00

  • Massive gastrointestinal bleeding associated with hookworm infestation in a child: case report.

    abstract::We report a rare case of massive haematochezia due to hookworm infestation that required two laparotomies before the cause of bleeding could be diagnosed. The need to consider this parasite as a possible cause of gut bleeding in endemic countries is stressed, as early recognition may avoid unnecessary investigations a...

    journal_title:Pediatric surgery international

    pub_type: 杂志文章

    doi:10.1007/BF00497827

    authors: Minocha A,Mitra DK,Sahni P,Karak A

    更新日期:1996-06-01 00:00:00