Cerebellar mutism.

Abstract:

:Cerebellar mutism occurs in about 25% of children following posterior fossa tumor surgery. It is usually accompanied by other neurological and behavioral disturbances. Mutism is transient in nature lasting several days to months and is frequently followed by dysarthria. In addition, impairment of language and other neuropsychological functions can be found after long term follow up in the majority of patients. The pathophysiological background of mutism may be higher speech dysfunction mediated by crossed cerebello-cerebral diaschisis which is frequently found during the mute period. Foremost injury to the bilateral dentatothalamocortical tract appears to be critical for the development of cerebello-cerebral diaschisis and subsequent mutism. Direct cerebellar injury is the likely reason for persisting deficits after the mute period. Minimization of injury to the dentatothalamocortical tract during surgery may be promising in the prevention of mutism. While there is no established treatment of mutism, early speech and rehabilitation therapy is recommended.

journal_name

Brain Lang

journal_title

Brain and language

authors

Küper M,Timmann D

doi

10.1016/j.bandl.2013.01.001

subject

Has Abstract

pub_date

2013-12-01 00:00:00

pages

327-33

issue

3

eissn

0093-934X

issn

1090-2155

pii

S0093-934X(13)00016-3

journal_volume

127

pub_type

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