Abstract：
OBJECTIVE:To assess and characterize the temporal variation in ovarian cancer incidence and mortality by age within countries in the Americas, Europe, Asia, and Oceania. METHODS/MATERIALS:Data from the National Cancer Institute's Surveillance, Epidemiology, and End Results Program in the United States (U.S.) were used to assess ovarian cancer incidence rates (1998-2008) and mortality rates, (1988-2007 for 12-month survival, 1988-2006 for 24-month survival, and 1988-2003 for 60-month survival), stratified by age at diagnosis. Data from GLOBOCAN were used to calculate country-specific incidence rates for 2010 and 2020 and case-fatality rates for 2010. RESULTS:A statistically significant decrease in Annual Percent Change (APC) of ovarian cancer incidence was observed in the U.S. for all women (-1.03%), among women who were diagnosed at <65 years of age (-1.09%) and among women who were diagnosed at ≥65 years of age (-0.95%). There was a statistically significant increase in the observed APC for survival at 12-months (0.19%), 24-months (0.58%), and 60-months (0.72%) for all women; however, 5-year survival for advanced stage (III or IV) disease was low at less than 50% for women <65 years and less than 30% for women ≥65 years. Global results showed a wide range in ovarian cancer incidence rates, with China exhibiting the lowest rates and the Russian Federation and the United Kingdom exhibiting the highest rates. CONCLUSIONS:Ovarian cancer survival has shown modest improvement from a statistical perspective in the U.S. However, it is difficult to ascertain how clinically relevant these improvements are at the population or patient level.
journal_name
Gynecol Oncoljournal_title
Gynecologic oncologyauthors
Lowe KA,Chia VM,Taylor A,O'Malley C,Kelsh M,Mohamed M,Mowat FS,Goff Bdoi
10.1016/j.ygyno.2013.03.026subject
Has Abstractpub_date
2013-07-01 00:00:00pages
107-14issue
1eissn
0090-8258issn
1095-6859pii
S0090-8258(13)00181-9journal_volume
130pub_type
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pub_type： 杂志文章,多中心研究,随机对照试验
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journal_title：Gynecologic oncology
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journal_title：Gynecologic oncology
pub_type： 杂志文章,评审
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journal_title：Gynecologic oncology
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journal_title：Gynecologic oncology
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journal_title：Gynecologic oncology
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更新日期：2017-02-01 00:00:00
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journal_title：Gynecologic oncology
pub_type： 杂志文章,多中心研究,随机对照试验
doi：10.1016/j.ygyno.2015.04.026
更新日期：2015-07-01 00:00:00
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journal_title：Gynecologic oncology
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journal_title：Gynecologic oncology
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doi：10.1006/gyno.1994.1043
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journal_title：Gynecologic oncology
pub_type： 杂志文章
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doi：10.1006/gyno.1995.1098
更新日期：1995-04-01 00:00:00
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journal_title：Gynecologic oncology
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doi：10.1016/j.ygyno.2010.03.015
更新日期：2010-07-01 00:00:00
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journal_title：Gynecologic oncology
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doi：10.1016/j.ygyno.2010.11.031
更新日期：2011-04-01 00:00:00
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journal_title：Gynecologic oncology
pub_type： 杂志文章,多中心研究
doi：10.1016/j.ygyno.2013.04.009
更新日期：2013-07-01 00:00:00
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journal_title：Gynecologic oncology
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doi：10.1016/j.ygyno.2008.01.030
更新日期：2008-05-01 00:00:00
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journal_title：Gynecologic oncology
pub_type： 杂志文章
doi：10.1016/j.ygyno.2004.03.038
更新日期：2004-07-01 00:00:00
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journal_title：Gynecologic oncology
pub_type： 杂志文章,多中心研究
doi：10.1016/j.ygyno.2016.11.042
更新日期：2017-02-01 00:00:00
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journal_title：Gynecologic oncology
pub_type： 杂志文章
doi：10.1016/0090-8258(90)90063-q
更新日期：1990-09-01 00:00:00
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journal_title：Gynecologic oncology
pub_type： 杂志文章
doi：10.1016/s0090-8258(03)00053-2
更新日期：2003-04-01 00:00:00
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pub_type： 杂志文章
doi：10.1016/j.ygyno.2015.08.025
更新日期：2015-11-01 00:00:00
