Stage IIIC ovarian leiomyosarcoma in a premenopausal woman with multiple recurrences: prolonged survival with surgical therapy.

abstract：OBJECTIVE:Human leukocyte antigens (HLA) play an important role in presenting virus antigens to immune cells that are responsible for the clearance of virus-infected cells and tumor cells. Herein, we evaluated whether genetic variants of HLA-DP and HLA-DQ are associated with cervical cancer risk. METHODS:We genotyped ...

journal_title：Gynecologic oncology

authors： Jiang J,Li N,Shen Y,Liu J,Liu L,Du J,Lei Y,Wen Y,Yang L,Guo L,Zhang K,Qiang F,Wang S,Hu Z,Dai M,Shen H

更新日期：2013-05-01 00:00:00

abstract：OBJECTIVE:To compare the detection rate of genital human papillomavirus (HPV) infection in self- and physician-obtained samples. DESIGN:Systematic review and meta-analysis. DATA SOURCES:Studies published between 1966 and November 2005 identified through Medline and Embase that compared both sampling methods. MAIN OU...

journal_title：Gynecologic oncology

authors： Petignat P,Faltin DL,Bruchim I,Tramèr MR,Franco EL,Coutlée F

更新日期：2007-05-01 00:00:00

abstract：BACKGROUND:Women with cervical cancer constitute a patient population in need for ongoing, person-centred supportive care. Our aim was to synthesise current available evidence with regard to the supportive care needs of women living with and beyond cervical cancer. METHODS:A systematic review was conducted according t...

journal_title：Gynecologic oncology

authors： Maguire R,Kotronoulas G,Simpson M,Paterson C

更新日期：2015-03-01 00:00:00

abstract：BACKGROUND:Gestational choriocarcinoma is a malignant tumor that frequently metastasizes to the highly vascularized organs such as the lung, brain, and liver via hematogenous spread. However, this tumor rarely metastasizes to the eye and only a few cases of metastasis to the choroid have been reported. CASE:A 17-year-...

journal_title：Gynecologic oncology

authors： Ino K,Mitsui T,Nomura S,Kikkawa F,Mizutani S

更新日期：2001-12-01 00:00:00

abstract：OBJECTIVES:To examine the impact of treatment- and disease-related factors on the quality of life of patients with ovarian cancers undergoing chemotherapy. PATIENTS AND METHODS:Over 18 months period, all patients with ovarian cancer receiving chemotherapy at the Saskatoon Cancer Center were recruited. The Functional A...

journal_title：Gynecologic oncology

authors： Le T,Leis A,Pahwa P,Wright K,Ali K,Reeder B,Hopkins L,Fung MF

更新日期：2004-03-01 00:00:00

abstract：:We performed a study to evaluate the relationships between the surgical stage (FIGO, 1989), histological tumor grade, myometrial invasion, peritoneal cytology, lymph node metastasis and prognosis, and DNA ploidy determined by flow cytometry in paraffin-embedded blocks of resected cancer lesions from 76 patients with u...

journal_title：Gynecologic oncology

authors： Ikeda M,Watanabe Y,Nanjoh T,Noda K

更新日期：1993-07-01 00:00:00

abstract：:Human papillomavirus (HPV) has been implicated in the development of cervical cancer. Newly developed molecular techniques have facilitated HPV identification and typing of cervical lesions. Several studies have suggested a strong correlation between HPV16 and intraepithelial cervical neoplasia. However, there is no a...

journal_title：Gynecologic oncology

authors： Pasetto N,Sesti F,De Santis L,Piccione E,Novelli G,Dallapiccola B

更新日期：1992-07-01 00:00:00

abstract：:The clinical pharmacology of cisplatin was determined in six patients with malignant ascites secondary to ovarian cancer, and in one patient with peritoneal mesothelioma, following intraperitoneal administration of cisplatin (25-60 mg/m2). The drug was administered in 1 liter of normal saline as a 15- to 30-min infusi...

journal_title：Gynecologic oncology

authors： Lopez JA,Krikorian JG,Reich SD,Smyth RD,Lee FH,Issell BF

更新日期：1985-01-01 00:00:00

abstract：:Retrospective review of sections of ovary from 50 patients with stage I, grade 1-3, epithelial ovarian carcinoma was performed to assess presence of cellular and nuclear atypia in noncancerous tissue adjacent to the primary tumor; ovarian tissue from 50 patients undergoing incidental oophorectomy was reviewed as well....

journal_title：Gynecologic oncology

authors： Plaxe SC,Deligdisch L,Dottino PR,Cohen CJ

更新日期：1990-09-01 00:00:00

abstract：:Primary adenocarcinoma of the vulva is rare, and cloagocenic adenocarcinoma of the vulva is extremely rare. Here we report a vulvar tumor characterized by columnar cells with prominent brush border and the presence of goblet cells and endocrine cells, presenting the tubulovillous pattern and mucin histochemistry of en...

journal_title：Gynecologic oncology

authors： Willén R,Békássy,Carlén B,Bozoky B,Cajander S

更新日期：1999-08-01 00:00:00

abstract：OBJECTIVE:The presence of metastases to regional lymph nodes (LN) is the single most important risk factor in endometrial cancer. Advances in molecular biology have provided more sensitive methods for detecting micrometastasis. This was a pilot study to determine whether cytokeratin staining of LN from endometrial canc...

journal_title：Gynecologic oncology

authors： Gonzalez Bosquet J,Keeney GL,Mariani A,Webb MJ,Cliby WA

更新日期：2003-12-01 00:00:00

abstract：BACKGROUND:Vulvar synovial cell sarcomas are rare, with only four previously published cases in the literature. Traditionally, the primary management for these tumors has been surgery alone. CASE:We report a case of a large vulvar synovial cell sarcoma in a 50-year-old woman treated with comprehensive combined multimo...

journal_title：Gynecologic oncology

authors： Holloway CL,Russell AH,Muto M,Albert M,Viswanathan AN

更新日期：2007-01-01 00:00:00

abstract：OBJECTIVES:To evaluate the role of LPA in regulating E-cadherin cell surface expression, adhesion, and invasion in epithelial ovarian carcinoma (EOC) cells. METHODS:E-cadherin mRNA expression in OVCA429 and IOSE-29 cells was evaluated by real-time RT-PCR. Immunofluorescence and Western blot analysis were performed to ...

journal_title：Gynecologic oncology

authors： Gil OD,Lee C,Ariztia EV,Wang FQ,Smith PJ,Hope JM,Fishman DA

更新日期：2008-02-01 00:00:00

abstract：:The interaction of human gestational choriocarcinoma cell line, SMT-cc1, with bovine vascular endothelial cells, CPAE, was examined in an in vitro coculture model. SMT-cc1 cells have urokinase-type plasminogen activator (uPA) on their cell surface, and more than half of the cell-associated uPA is enzymatically inactiv...

journal_title：Gynecologic oncology

authors： Sugimura M,Kobayashi H,Terao T

更新日期：1994-03-01 00:00:00

abstract：OBJECTIVE:We sought to determine whether DNA ploidy correlates with the four molecular subgroups of endometrial carcinoma (EC) as determined using ProMisE (Proactive Molecular Risk Classifier for Endometrial Cancer). METHODS:90 cases of EC previously characterized by clinicopathological parameters, outcomes, and ProMi...

journal_title：Gynecologic oncology

authors： Proctor L,Pradhan M,Leung S,Cheng A,Lee CH,Soslow RA,Gilks CB,Talhouk A,McAlpine JM,Danielsen HE,Hoang LN

更新日期：2017-09-01 00:00:00

abstract：BACKGROUND:Cutaneous lymphangitis carcinomatosis from cervical carcinoma is a very rare form of tumor metastatization; only anecdotal cases are reported in the literature. Most of the patients with skin relapse experienced metastasis as a single or multiple nodules. CASE:A case of cutaneous lymphangitis carcinomatosis...

journal_title：Gynecologic oncology

authors： Palaia I,Angioli R,Cutillo G,Manci N,Panici PB

更新日期：2002-10-01 00:00:00

abstract：BACKGROUND:Improvements in surgical technique of pelvic exenteration have mainly occurred in the reconstructive phase of the procedure. Quality of life seems to be improved when performing continent rather than non-continent urinary diversion [1]. Unfortunately, Miami continent urinary pouch is a surgical technique not...

journal_title：Gynecologic oncology

authors： Angeles MA,Martínez-Gómez C,Martinez A,Ferron G

更新日期：2018-08-01 00:00:00

abstract：OBJECTIVES:To prospectively evaluate the diagnostic value of combined PET/CT in detecting a malignant tumor in patients with no previous cancer history, presenting with a pelvic mass. METHODS:From September 2004 to March 2006, 101 patients (median age=60 years, range=24-85 years) with a Risk of Malignancy Index (RMI)>...

journal_title：Gynecologic oncology

authors： Risum S,Høgdall C,Loft A,Berthelsen AK,Høgdall E,Nedergaard L,Lundvall L,Engelholm SA

更新日期：2007-04-01 00:00:00

abstract：OBJECTIVES:The objective of this study was to determine whether the length of the interval from primary surgery to commencement of chemotherapy has any direct effect on progression-free survival in ovarian cancer. METHODS:The progression-free survival of 472 patients enrolled in four trials who had all received platin...

journal_title：Gynecologic oncology

authors： Flynn PM,Paul J,Cruickshank DJ,Scottish Gynaecological Cancer Trials Group.

更新日期：2002-09-01 00:00:00

abstract：:For over forty years, the Gynecologic Oncology Group drove progress in treating endometrial cancer. The first decades of investigation began with a meticulous prospective, surgicopathologic staging study that was the platform for development of all subsequent trials. The resultant statistical model of low risk, interm...

journal_title：Gynecologic oncology

authors： Miller DS,Randall ME,Filiaci V

更新日期：2020-05-01 00:00:00

abstract：:Ovarian management at the time of radical hysterectomy for cervical cancer was reviewed retrospectively over a 7-year period. All patients had early-stage cancer except three who had stage IIB disease. Approximately 80% of patients had squamous cancer and 20% adenocarcinoma or adenosquamous carcinoma. The mean age was...

journal_title：Gynecologic oncology

authors： Owens S,Roberts WS,Fiorica JV,Hoffman MS,LaPolla JP,Cavanagh D

更新日期：1989-12-01 00:00:00

abstract：OBJECTIVE:This study explores patterns of lifestyle change and whether more threatening illness perceptions are associated with lifestyle changes post-treatment for smoking, alcohol consumption and Body Mass Index (BMI) among gynecological cancer patients. METHODS:In total, 395 cancer patients (N=221 endometrial; N=17...

journal_title：Gynecologic oncology

authors： van Broekhoven MECL,de Rooij BH,Pijnenborg JMA,Vos MC,Boll D,Kruitwagen RFPM,van de Poll-Franse LV,Ezendam NPM

更新日期：2017-05-01 00:00:00

abstract：OBJECTIVE:Recent prospective data support the trend towards systematic retroperitoneal lymphadenectomy in patients with high-risk endometrial cancer. Because para-aortic node involvement in the absence of pelvic node involvement is uncommon, a reliable finding of negative pelvic lymph nodes (PLN) at intraoperative froz...

journal_title：Gynecologic oncology

authors： Pristauz G,Bader AA,Regitnig P,Haas J,Winter R,Tamussino K

更新日期：2009-10-01 00:00:00

abstract：OBJECTIVES:To assess sexual function of vulvar cancer survivors who received extensive and less extensive treatment. To explore associations between sexual function and patient, disease, treatment, and psychological variables. METHODS:Sexual function (Female Sexual Function Index, FSFI), mental and physical well-being...

journal_title：Gynecologic oncology

authors： Hazewinkel MH,Laan ET,Sprangers MA,Fons G,Burger MP,Roovers JP

更新日期：2012-07-01 00:00:00

abstract：OBJECTIVE:Perform a systematic review to determine the test performance of HPV mRNA testing compared to DNA testing using CIN2+ as the target condition. METHODS:We searched bibliographic databases (MEDLINE, EMBASE and Cochrane Library) from January 1996 through August 2010 using a predefined search strategy. The refer...

journal_title：Gynecologic oncology

authors： Burger EA,Kornør H,Klemp M,Lauvrak V,Kristiansen IS

更新日期：2011-03-01 00:00:00

abstract：:The radical hysterectomy is often associated with severe bladder dysfunction and colorectal motility disorders. These issues may arise as a result of damage incurred to the motor and sensory autonomic nerve supply, both of sympathetic and parasympathetic origin, that innervate the uterus, vagina, urinary bladder, and ...

journal_title：Gynecologic oncology

authors： Fujii S

更新日期：2008-11-01 00:00:00

abstract：OBJECTIVE:Despite the fact that endometrial cancer commonly occurs in elderly women, little is known about the outcome of the oldest old, those > 80 years of age. We examined the patterns of care and outcome of the oldest old women with endometrial cancer. METHODS:An analysis of women > 65 years of age with endometrio...

journal_title：Gynecologic oncology

authors： Wright JD,Lewin SN,Barrena Medel NI,Sun X,Burke WM,Deutsch I,Herzog TJ

更新日期：2011-07-01 00:00:00

abstract：OBJECTIVES:Based on our previous report showing that orobol, a potent phosphatidylinositol 4-kinase (PI4K) inhibitor, produced cisplatin (DDP) sensitivity, we have determined the mechanism of orobol-sensitization effect. METHODS AND RESULTS:Orobol produced >2-fold DDP sensitivity in human ovarian carcinoma 2008 cells ...

journal_title：Gynecologic oncology

authors： Isonishi S,Saitou M,Yasuda M,Ochiai K,Tanaka T

更新日期：2003-08-01 00:00:00

abstract：:The Precision Medicine Initiative is a National Cancer Institute (NCI) driven interdisciplinary collaborative effort to test the feasibility of trials incorporating genomic profiling when choosing patient therapies. The goal of the initiative is to generate the scientific evidence needed to move the concept of precisi...

journal_title：Gynecologic oncology

authors： Barroilhet L,Matulonis U

更新日期：2018-03-01 00:00:00

abstract：OBJECTIVE:To increase genetic counseling referrals for patients with newly diagnosed epithelial ovarian cancer (EOC). METHODS:A practice-gap analysis was performed after measuring baseline genetic counseling referral rates to identify barriers to referral from the multidisciplinary single institution EOC care group. A...

journal_title：Gynecologic oncology

authors： Swanson CL,Kumar A,Maharaj JM,Kemppainen JL,Thomas BC,Weinhold MR,Slaby KM,Mara KC,Wick MJ,Bakkum-Gamez JN

更新日期：2018-04-01 00:00:00