当前位置： SCI文献检索 > GYNECOLOGIC ONCOLOGY期刊下所有文献 > Complete remission of gestational choriocarcinoma with choroidal metastasis treated with systemic chemotherapy alone: case report and review of literature.

Complete remission of gestational choriocarcinoma with choroidal metastasis treated with systemic chemotherapy alone: case report and review of literature.

Abstract：

BACKGROUND:Gestational choriocarcinoma is a malignant tumor that frequently metastasizes to the highly vascularized organs such as the lung, brain, and liver via hematogenous spread. However, this tumor rarely metastasizes to the eye and only a few cases of metastasis to the choroid have been reported. CASE:A 17-year-old woman presented with visual field defects, decreased vision, and increasing pain in her left eye. She had undergone evacuation of a complete hydatidiform mole 32 months prior to the presentation. Ophthalmologic evaluation revealed a metastatic choroidal tumor, and a CT scan showed a metastatic tumor in the left lung. The serum hCG level was elevated at 7780 mIU/ml. A clinical diagnosis of metastatic gestational choriocarcinoma involving the choroid and lung was made. The patient received 13 courses of combination chemotherapy, resulting in complete remission. Radiotherapy and surgical treatment were unnecessary. CONCLUSION:This is a very rare case of the successful treatment of gestational choriocarcinoma metastatic to the choroid using systemic chemotherapy alone.

journal_name

Gynecol Oncol

journal_title

Gynecologic oncology

authors

Ino K,Mitsui T,Nomura S,Kikkawa F,Mizutani S

doi

10.1006/gyno.2001.6415

subject

Has Abstract

pub_date

2001-12-01 00:00:00

pages

601-4

issue

3

eissn

0090-8258

issn

1095-6859

pii

S0090-8258(01)96415-7

journal_volume

83

pub_type

杂志文章,评审

相关文献

GYNECOLOGIC ONCOLOGY文献大全
  • Angiomyofibroblastoma of the vulva.

    abstract：:Angiomyofibroblastoma is a rare, myxoid tumor of the vulva. To date only 12 cases have been reported in the world literature. Patients are usually premenopausal and present with a vulval mass initially diagnosed as a Bartholin's cyst. The lesions are well circumscribed and range from 0.5 to 12 cm in size. Microscopica...

    journal_title：Gynecologic oncology

    pub_type： 杂志文章

    doi：10.1006/gyno.1994.1230

    authors： Van der Griend MD,Burda P,Ferrier AJ

    更新日期：1994-09-01 00:00:00

  • Frontline PARP inhibitor maintenance therapy in ovarian cancer: A Society of Gynecologic Oncology practice statement.

    abstract：:PARP inhibitors (PARPi) have shown have activity in the treatment of ovarian cancer. Previous studies documented activity in patients with germline (gBRCA) and tumor (tBRCA) BRCA mutations (BRCAm) for treatment in lieu of chemotherapy as well as in recurrent ovarian cancer as maintenance therapy. The recent data from ...

    journal_title：Gynecologic oncology

    pub_type： 杂志文章

    doi：10.1016/j.ygyno.2020.07.097

    authors： Pothuri B,O'Cearbhaill R,Eskander R,Armstrong D

    更新日期：2020-10-01 00:00:00

  • Malignant struma ovarii: recurrence and response to treatment monitored by thyroglobulin levels.

    abstract：:A patient with malignant struma ovarii who had elevated thyroglobulin levels at the time of her original surgery was diagnosed with recurrence on the basis of progressive thyroglobulin level elevation while on thyroid suppressive therapy. Subsequent treatment with therapeutic doses of iodine-137 resulted in normalizat...

    journal_title：Gynecologic oncology

    pub_type： 杂志文章

    doi：10.1006/gyno.1998.5056

    authors： Rose PG,Arafah B,Abdul-Karim FW

    更新日期：1998-09-01 00:00:00

  • Incidence of symptomatic deep venous thrombosis with epoetin alfa or darbepoetin alfa treatment of anemia in patients with ovarian or primary peritoneal cancer.

    abstract：OBJECTIVES:Recombinant epoetin alfa and darbepoetin alfa (r-HuEPO) have been shown to be safe and effective treatments for anemia, but recent reports have suggested an increased risk of thromboembolic events when these agents are used to treat chemotherapy-induced anemia among patients with breast or ovarian cancer. We...

    journal_title：Gynecologic oncology

    pub_type： 杂志文章

    doi：10.1016/j.ygyno.2006.12.026

    authors： Westin SN,Skinner EN,Jonsson Funk M,Gehrig PM,Van Le L

    更新日期：2007-05-01 00:00:00

  • A cut-off value of 2 cm in tumor size is of prognostic value in surgically treated FIGO stage IB cervical cancer.

    abstract：OBJECTIVES:Limited knowledge exists about the value of tumor size in surgically treated cervical cancer (CX) using a tumor size of 2 cm as cut-off value. METHODS:A total of 366 cases of CX FIGO stage IB who received upfront surgery were evaluated regarding tumor size, the prediction of pelvic lymph node involvement, a...

    journal_title：Gynecologic oncology

    pub_type： 杂志文章

    doi：10.1016/j.ygyno.2014.04.011

    authors： Horn LC,Bilek K,Fischer U,Einenkel J,Hentschel B

    更新日期：2014-07-01 00:00:00

  • Human papillomavirus analysis as a prognostic marker following conization of the cervix uteri.

    abstract：:Cervical intraepithelial neoplasia grade 3 (CIN 3) is treated surgically. Follow-up of these patients is important to ensure successful treatment. The present study was undertaken to determine whether human papillomavirus (HPV) testing can be used to discriminate patients who will have recurrences from those who will ...

    journal_title：Gynecologic oncology

    pub_type： 临床试验,杂志文章

    doi：10.1006/gyno.1997.4753

    authors： Chua KL,Hjerpe A

    更新日期：1997-07-01 00:00:00

  • Clinical and pathologic findings of prophylactic salpingo-oophorectomies in 159 BRCA1 and BRCA2 carriers.

    abstract：OBJECTIVE:To estimate the likelihood of occult cancer diagnosis at prophylactic oophorectomy in BRCA1 and BRCA2 carriers in different age groups and to determine the histopathology of these lesions. METHODS:We describe a series of 159 female BRCA1 or BRCA2 carriers who underwent prophylactic oophorectomy at the Univer...

    journal_title：Gynecologic oncology

    pub_type： 杂志文章

    doi：10.1016/j.ygyno.2005.06.065

    authors： Finch A,Shaw P,Rosen B,Murphy J,Narod SA,Colgan TJ

    更新日期：2006-01-01 00:00:00

  • A randomized study of the effectiveness of a brief psychosocial intervention for women attending a gynecologic cancer clinic.

    abstract：OBJECTIVES:While there are many psychosocial interventions for cancer patients, few are brief in nature. The aim of this study was to investigate the usefulness of a single-visit psychosocial intervention for gynecologic cancer patients. METHODS:One hundred women attending a gynecologic cancer clinic as new patients w...

    journal_title：Gynecologic oncology

    pub_type： 杂志文章,随机对照试验

    doi：10.1016/j.ygyno.2008.06.024

    authors： Powell CB,Kneier A,Chen LM,Rubin M,Kronewetter C,Levine E

    更新日期：2008-10-01 00:00:00

  • Changes in health-related quality of life in older women after diagnosis with gynecologic cancer.

    abstract：PURPOSE:The impact of gynecologic cancer on health-related quality of life (HRQOL) is not fully understood. To our knowledge, this is the first longitudinal study to measure HRQOL changes from before to after gynecologic cancer diagnosis in older women. METHODS:Data were obtained from the Surveillance, Epidemiology, a...

    journal_title：Gynecologic oncology

    pub_type： 杂志文章

    doi：10.1016/j.ygyno.2019.11.033

    authors： Klapheke AK,Keegan THM,Ruskin R,Cress RD

    更新日期：2020-02-01 00:00:00

  • Effective chemotherapy consisting of bleomycin, vincristine, mitomycin C, and cisplatin (BOMP) for a patient with inoperable vulvar cancer.

    abstract：:Combination chemotherapy consisting of bleomycin, vincristine, mitomycin C, and cisplatin (BOMP) was first applied to an inoperable case (57-year-old) with FIGO stage IV (T3N3 + M1B) squamous cell carcinoma of the vulva. After three courses of BOMP therapy, the patient achieved a complete response with few toxic effec...

    journal_title：Gynecologic oncology

    pub_type： 杂志文章

    doi：10.1016/0090-8258(90)90156-f

    authors： Shimizu Y,Hasumi K,Masubuchi K

    更新日期：1990-03-01 00:00:00

  • Mutational analysis of the BRCA1 tumor suppressor gene in endometrial carcinoma.

    abstract：OBJECTIVE:To investigate whether alteration of BRCA1 tumor suppressor gene occurs in sporadic endometrial carcinomas. METHODS:Genomic DNAs were prepared from 33 consecutively collected endometrial carcinoma tissues for BRCA1 mutational analysis. To screen for BRCA1 mutation, polymerase chain reaction (PCR) amplificati...

    journal_title：Gynecologic oncology

    pub_type： 杂志文章

    doi：10.1006/gyno.1997.4800

    authors： Liu FS,Ho ES,Shih RT,Shih A

    更新日期：1997-09-01 00:00:00

  • Loss of Fhit expression as a potential marker of malignant progression in preinvasive squamous cervical cancer.

    abstract：OBJECTIVE:In a previous study using the same cases of squamous cervical neoplasia and microinvasive carcinoma (MICA) we found an association between FHIT gene deletion and infection with high-risk HPV (HR HPV). The purpose of this study was to evaluate Fhit protein expression by immunohistochemistry in order to determi...

    journal_title：Gynecologic oncology

    pub_type： 杂志文章

    doi：10.1006/gyno.2002.6712

    authors： Butler D,Collins C,Mabruk M,Leader MB,Kay EW

    更新日期：2002-08-01 00:00:00

  • Carboplatin plus paclitaxel combination chemotherapy: impact of sequence of drug administration on treatment-induced neutropenia.

    abstract：OBJECTIVE:While the importance of the sequence of administration of cisplatin and paclitaxel on the degree of observed neutropenia has been documented, there is limited information available in the oncology literature to determine whether there exists sequence-dependent toxicity for the combination of carboplatin plus ...

    journal_title：Gynecologic oncology

    pub_type： 临床试验,杂志文章,随机对照试验

    doi：10.1016/s0090-8258(03)00517-1

    authors： Markman M,Elson P,Kulp B,Peterson G,Zanotti K,Webster K,Belinson J

    更新日期：2003-10-01 00:00:00

  • Survival impact of multiple bowel resections in patients undergoing primary cytoreductive surgery for advanced ovarian cancer: a case-control study.

    abstract：OBJECTIVE:To evaluate clinicopathological factors and survival outcome of patients with advanced epithelial ovarian carcinoma undergoing multiple bowel resections to achieve optimal (< or = 1 cm) cytoreduction. METHODS:A case-control study was performed identifying patients undergoing optimal primary cytoreductive sur...

    journal_title：Gynecologic oncology

    pub_type： 杂志文章

    doi：10.1016/j.ygyno.2007.08.003

    authors： Salani R,Zahurak ML,Santillan A,Giuntoli RL 2nd,Bristow RE

    更新日期：2007-12-01 00:00:00

  • Interferon gamma treatment for cervical intraepithelial neoplasia.

    abstract：:Eight patients with cervical intraepithelial neoplasia (CIN) were administered perilesional injections of human recombinant interferon gamma (IFN-gamma), and the response was evaluated by colposcopy and exfoliative cytology and then by histopathology. In all patients, colposcopic and cytologic findings improved after ...

    journal_title：Gynecologic oncology

    pub_type： 杂志文章

    doi：10.1016/0090-8258(90)90316-d

    authors： Iwasaka T,Hayashi Y,Yokoyama M,Hachisuga T,Sugimori H

    更新日期：1990-04-01 00:00:00

  • Endometrial cancer in morbidly obese women: do racial disparities affect surgical or survival outcomes?

    abstract：OBJECTIVE:Endometrial cancer mortality disproportionately affects black women and whether greater prevalence of obesity plays a role in this disparity is unknown. We examine the effect of race on post-surgical complications, length of stay, and mortality specifically in a morbidly obese population. METHODS:Black and w...

    journal_title：Gynecologic oncology

    pub_type： 杂志文章

    doi：10.1016/j.ygyno.2014.01.013

    authors： Cote ML,Ruterbusch JJ,Ahmed Q,Bandyopadhyay S,Alosh B,Abdulfatah E,Seward S,Morris R,Ali-Fehmi R

    更新日期：2014-04-01 00:00:00

  • Sarcoma in association with multimodality management of vulvar cancer: two case reports.

    abstract：BACKGROUND:Radiation-induced or -associated sarcoma is a rare event which has been well described in the literature. However, this entity has been infrequently described in association with genital tract malignancies. To our knowledge it has never been described in association with the management of vulvar cancer. CAS...

    journal_title：Gynecologic oncology

    pub_type： 杂志文章

    doi：10.1006/gyno.2001.6139

    authors： Hyde S,Uitterhoeve LJ,Schilthuis MS,ten Kate FJ,van der Velden J

    更新日期：2001-05-01 00:00:00

  • Intraperitoneal catheter outcomes in a phase III trial of intravenous versus intraperitoneal chemotherapy in optimal stage III ovarian and primary peritoneal cancer: a Gynecologic Oncology Group Study.

    abstract：OBJECTIVES:To evaluate reasons for discontinuing intraperitoneal (IP) chemotherapy, and to compare characteristics of patients who did versus did not successfully complete six cycles of IP chemotherapy. METHODS:In a phase III trial, women with optimal stage III ovarian or peritoneal carcinoma were randomly allocated t...

    journal_title：Gynecologic oncology

    pub_type： 杂志文章,多中心研究,随机对照试验

    doi：10.1016/j.ygyno.2005.11.013

    authors： Walker JL,Armstrong DK,Huang HQ,Fowler J,Webster K,Burger RA,Clarke-Pearson D

    更新日期：2006-01-01 00:00:00

  • The validity and significance of substage IIIC by node involvement in epithelial ovarian cancer: impact of nodal metastasis on patient survival.

    abstract：OBJECTIVE:The aim of this study was to examine whether there is a possible difference in patient survival (1) between node-positive and node-negative groups for Stage I, II, IIIA+B, and IIIC disease and (2) between node-positive Stage I through IIIB disease and Stage IIIC disease. METHODS:Medical records of 125 patien...

    journal_title：Gynecologic oncology

    pub_type： 杂志文章

    doi：10.1006/gyno.1999.5349

    authors： Kanazawa K,Suzuki T,Tokashiki M

    更新日期：1999-05-01 00:00:00

  • Placebo-controlled trial of indole-3-carbinol in the treatment of CIN.

    abstract：OBJECTIVE:Most precancerous lesions of the cervix are treated with surgery or ablative therapy. Chemoprevention, using natural and synthetic compounds, may intervene in the early precancerous stages of carcinogenesis and prevent the development of invasive disease. Our trial used indole-3-carbinol (I-3-C) administered ...

    journal_title：Gynecologic oncology

    pub_type： 临床试验,杂志文章,随机对照试验

    doi：10.1006/gyno.2000.5847

    authors： Bell MC,Crowley-Nowick P,Bradlow HL,Sepkovic DW,Schmidt-Grimminger D,Howell P,Mayeaux EJ,Tucker A,Turbat-Herrera EA,Mathis JM

    更新日期：2000-08-01 00:00:00

  • Clinical and imaging findings in cervical cancer and their impact on FIGO and TNM staging - An analysis from the EMBRACE study.

    abstract：OBJECTIVE:To investigate differences in local tumour staging between clinical examination and MRI and differences between FIGO 2009, FIGO 2018 and TNM in patients with primary cervical cancer undergoing definitive radio-chemotherapy. METHODS:Patients from the prospective observational multi-centre study "EMBRACE" were...

    journal_title：Gynecologic oncology

    pub_type： 杂志文章

    doi：10.1016/j.ygyno.2020.07.007

    authors： Knoth J,Pötter R,Jürgenliemk-Schulz IM,Haie-Meder C,Fokdal L,Sturdza A,Hoskin P,Mahantshetty U,Segedin B,Bruheim K,Wiebe E,Rai B,Cooper R,van der Steen-Banasik E,van Limbergen E,Pieters BR,Sundset M,Tan LT,Nout RA,T

    更新日期：2020-10-01 00:00:00

  • Clear cell carcinoma of the ovary: a study of 59 cases.

    abstract：:Clear cell carcinoma of the ovary accounts for 2 to 3% of all epithelial ovarian neoplasms. Patient profiles, pathological characteristics, and results of treatment are reviewed for 59 patients. The median age was 51. Disease extent at diagnosis was as follows: stage I, 18 patients (31%); stage II, 20 patients (34%); ...

    journal_title：Gynecologic oncology

    pub_type： 杂志文章

    doi：10.1016/0090-8258(89)90043-7

    authors： Crozier MA,Copeland LJ,Silva EG,Gershenson DM,Stringer CA

    更新日期：1989-11-01 00:00:00

  • Classification and regression tree (CART) analysis of endometrial carcinoma: Seeing the forest for the trees.

    abstract：OBJECTIVE:The objectives of the study are to evaluate which clinicopathologic factors influenced overall survival (OS) in endometrial carcinoma and to determine if the surgical effort to assess para-aortic (PA) lymph nodes (LNs) at initial staging surgery impacts OS. METHODS:All patients diagnosed with endometrial can...

    journal_title：Gynecologic oncology

    pub_type： 杂志文章

    doi：10.1016/j.ygyno.2013.06.009

    authors： Barlin JN,Zhou Q,St Clair CM,Iasonos A,Soslow RA,Alektiar KM,Hensley ML,Leitao MM Jr,Barakat RR,Abu-Rustum NR

    更新日期：2013-09-01 00:00:00

  • Push-pull theory: using mechanotransduction to achieve tissue perfusion and wound healing in complex cases.

    abstract：:Wound healing has evolved from gauze therapy to the use of proteomics, gene therapy, and cellular-based therapies in the short time span of 45 years. Education for health care providers has not kept pace with the logarithmic acceleration in technology development and treatment options. A patient with a non-healing wou...

    journal_title：Gynecologic oncology

    pub_type： 杂志文章,评审

    doi：10.1016/j.ygyno.2008.07.054

    authors： Ennis WJ,Meneses P,Borhani M

    更新日期：2008-11-01 00:00:00

  • The prognostic significance of thrombocytosis in epithelial ovarian carcinoma.

    abstract：OBJECTIVE:The objective of this study was to determine the incidence of thrombocytosis in epithelial ovarian carcinoma and examine associations with clinico-pathologic features. Thrombocytosis (platelet counts >400 x 10(9)/l) has been identified as a poor prognostic factor in many cancers. Platelet-secreted factors may...

    journal_title：Gynecologic oncology

    pub_type： 杂志文章

    doi：10.1016/j.ygyno.2003.09.002

    authors： Li AJ,Madden AC,Cass I,Leuchter RS,Lagasse LD,Karlan BY

    更新日期：2004-01-01 00:00:00

  • Relationship between removal of circumflex iliac nodes distal to the external iliac nodes and postoperative lower-extremity lymphedema in uterine cervical cancer.

    abstract：OBJECTIVE:This study aimed to determine if there is a causal relationship between removal of the circumflex iliac nodes distal to the external iliac nodes (CINDEIN) and postoperative lower-extremity lymphedema (POLEL) after systematic lymphadenectomy in patients with cervical cancer. METHODS:A retrospective chart revi...

    journal_title：Gynecologic oncology

    pub_type： 杂志文章

    doi：10.1016/j.ygyno.2015.09.007

    authors： Yamazaki H,Todo Y,Takeshita S,Ohba Y,Sudo S,Minobe S,Okamoto K,Yamashiro K,Kato H

    更新日期：2015-11-01 00:00:00

  • Pseudo-Meigs' syndrome caused by a hydropic degenerating uterine leiomyoma with elevated CA 125.

    abstract：BACKGROUND:Uterine leiomyomas rarely cause pseudo-Meigs' syndrome with elevated serum CA 125 levels. CASE:A 39-year-old patient with a large uterine leiomyoma is described. The associated massive ascites, pleural fluid, and increased CA 125 level all seemed to be related to the uterine tumor. Hydropic degenerating lei...

    journal_title：Gynecologic oncology

    pub_type： 杂志文章

    doi：10.1006/gyno.2001.6251

    authors： Amant F,Gabriel C,Timmerman D,Vergote I

    更新日期：2001-10-01 00:00:00

  • Preoperative hypoalbuminemia is an independent predictor of poor perioperative outcomes in women undergoing open surgery for gynecologic malignancies.

    abstract：OBJECTIVE:To quantify the impact of preoperative hypoalbuminemia on 30-day mortality and morbidity after gynecologic cancer surgery. METHODS:Patients included in the National Surgical Quality Improvement Program (NSQIP) dataset who underwent any non-emergent surgery for gynecologic malignancy between 1/1/2008 and 12/3...

    journal_title：Gynecologic oncology

    pub_type： 杂志文章

    doi：10.1016/j.ygyno.2013.08.011

    authors： Uppal S,Al-Niaimi A,Rice LW,Rose SL,Kushner DM,Spencer RJ,Hartenbach E

    更新日期：2013-11-01 00:00:00

  • Tumorigenesis of K-ras mutation in human endometrial carcinoma via upregulation of estrogen receptor.

    abstract：OBJECTIVE:To investigate the tumorigenesis of mutant [12Asp]-K-ras in endometrial carcinoma and its relationship with ER. METHODS:We constructed pcDI-[12Asp]K-ras4B by inserting full-length [12Asp]K-ras4B from human endometrial carcinoma Hec-1A cells, into pcDI vector. Cell proliferation of NIH3T3 after transfection w...

    journal_title：Gynecologic oncology

    pub_type： 杂志文章

    doi：10.1016/j.ygyno.2005.10.016

    authors： Tu Z,Gui L,Wang J,Li X,Sun P,Wei L

    更新日期：2006-05-01 00:00:00

  • Carcinoma of the cervix in association with uterine prolapse.

    abstract：BACKGROUND:Carcinoma of the cervix and a prolapsed uterus are common diseases in underdeveloped countries, but their association is quite rare. CASE:We report here the clinical characteristics of two Brazilian patients with carcinoma of the uterine cervix associated with a third-degree prolapsed uterus. The patients, ...

    journal_title：Gynecologic oncology

    pub_type： 杂志文章

    doi：10.1006/gyno.2001.6503

    authors： da Silva BB,da Costa Araújo R,Filho CP,Melo JA

    更新日期：2002-02-01 00:00:00