Skin relapse from cervical cancer.

abstract：BACKGROUND:Hec1 (Highly Expressed in Cancer gene 1) has recently been shown to play an important role in the proper segregation of chromosomes during mitosis. Recently, an adenovirus delivery system carrying RNA interference (RNAi) of Hec1 has been reported in a cervical adenocarcinoma model. Adenoviral delivery system...

journal_title：Gynecologic oncology

authors： Numnum TM,Makhija S,Lu B,Wang M,Rivera A,Stoff-Khalili M,Alvarez RD,Zhu ZB,Curiel DT

更新日期：2008-01-01 00:00:00

abstract：OBJECTIVE:The aim of this study was to estimate the efficacy of an intensive CDP program, as well as to identify the predictors associated with lymphedema severity and response to CDP in lower limb lymphedema (LLL) after pelvic cancer therapy. METHODS:We performed a retrospective review of post-pelvic cancer LLL patie...

journal_title：Gynecologic oncology

authors： Liao SF,Li SH,Huang HY

更新日期：2012-06-01 00:00:00

abstract：OBJECTIVES:To investigate survival disparities and prognostic factors in vulvar cancer by age at diagnosis. METHODS:Women who underwent surgery and were diagnosed with stage I-IV vulvar cancer from 2004 to 2014 in the National Cancer Database were eligible. Proportions were compared using Chi-Square test. Survival was...

journal_title：Gynecologic oncology

authors： Gaulin NB,Lesnock JL,Tian C,Osei-Bonsu K,Jacobs A,Richard SD,Krivak TC,Miller EM,Shriver CD,Casablanca Y,Maxwell GL,Darcy KM

更新日期：2020-04-01 00:00:00

abstract：OBJECTIVE:The objective of this study was to determine the incidence of thrombocytosis in epithelial ovarian carcinoma and examine associations with clinico-pathologic features. Thrombocytosis (platelet counts >400 x 10(9)/l) has been identified as a poor prognostic factor in many cancers. Platelet-secreted factors may...

journal_title：Gynecologic oncology

authors： Li AJ,Madden AC,Cass I,Leuchter RS,Lagasse LD,Karlan BY

更新日期：2004-01-01 00:00:00

abstract：BACKGROUND:Endometrial polyps are the most common endometrial pathology described in association with postmenopausal tamoxifen exposure. It is generally accepted that the occurrence of malignancy in endometrial polyps among healthy women is up to 0.5%. However, no one has yet described the incidence of this malignant t...

journal_title：Gynecologic oncology

authors： Cohen I,Bernheim J,Azaria R,Tepper R,Sharony R,Beyth Y

更新日期：1999-10-01 00:00:00

abstract：OBJECTIVE:Despite the fact that endometrial cancer commonly occurs in elderly women, little is known about the outcome of the oldest old, those > 80 years of age. We examined the patterns of care and outcome of the oldest old women with endometrial cancer. METHODS:An analysis of women > 65 years of age with endometrio...

journal_title：Gynecologic oncology

authors： Wright JD,Lewin SN,Barrena Medel NI,Sun X,Burke WM,Deutsch I,Herzog TJ

更新日期：2011-07-01 00:00:00

abstract：OBJECTIVE:BRCA-associated and sporadic ovarian cancers have different pathologic and clinical features. Our goal was to determine if BRCA mutation status is an independent predictor of residual tumor volume following primary surgical cytoreduction. METHODS:We conducted a retrospective analysis of patients with FIGO st...

journal_title：Gynecologic oncology

authors： Hyman DM,Long KC,Tanner EJ,Grisham RN,Arnold AG,Bhatia J,Phillips MF,Spriggs DR,Soslow RA,Kauff ND,Levine DA

更新日期：2012-08-01 00:00:00

abstract：OBJECTIVE:High-risk types of HPV are etiological factors in cervical cancer. Lymph node involvement in cervical cancer patients reduces 5-year survival rates by 25-60%. However, the influence on survival of HPV DNA positivity in histopathologically negative lymph nodes remains unresolved. METHODS:The study included 11...

journal_title：Gynecologic oncology

authors： Lukaszuk K,Liss J,Gulczynski J,Nowaczyk M,Nakonieczny M,Piatkowski M,Sliwinski W,Baay M,Wozniak I,Maj B,Lukaszuk M

更新日期：2007-03-01 00:00:00

abstract：:Eight patients with cervical intraepithelial neoplasia (CIN) were administered perilesional injections of human recombinant interferon gamma (IFN-gamma), and the response was evaluated by colposcopy and exfoliative cytology and then by histopathology. In all patients, colposcopic and cytologic findings improved after ...

journal_title：Gynecologic oncology

authors： Iwasaka T,Hayashi Y,Yokoyama M,Hachisuga T,Sugimori H

更新日期：1990-04-01 00:00:00

abstract：OBJECTIVE:Recent prospective data support the trend towards systematic retroperitoneal lymphadenectomy in patients with high-risk endometrial cancer. Because para-aortic node involvement in the absence of pelvic node involvement is uncommon, a reliable finding of negative pelvic lymph nodes (PLN) at intraoperative froz...

journal_title：Gynecologic oncology

authors： Pristauz G,Bader AA,Regitnig P,Haas J,Winter R,Tamussino K

更新日期：2009-10-01 00:00:00

abstract：:Wound healing has evolved from gauze therapy to the use of proteomics, gene therapy, and cellular-based therapies in the short time span of 45 years. Education for health care providers has not kept pace with the logarithmic acceleration in technology development and treatment options. A patient with a non-healing wou...

journal_title：Gynecologic oncology

authors： Ennis WJ,Meneses P,Borhani M

更新日期：2008-11-01 00:00:00

abstract：:By using monoclonal antibodies and flow cytometry, the phenotype and activation state [based on presence of interleukin 2 (IL-2) receptors] were determined on the mononuclear cell (MNC) fraction of ovarian carcinoma tissue from 12 patients. Thymidine incorporation response to IL-2 and phytohemagglutinin stimulation wa...

journal_title：Gynecologic oncology

authors： Lentz SS,McKean DJ,Kovach JS,Podratz KC

更新日期：1989-08-01 00:00:00

abstract：:A phase II trial of ifosfamide (IFX) and mesna was conducted by the GOG in patients with recurrent or advanced nonsquamous carcinoma of the cervix. A starting dose of 1.5 g/m2 IFX iv daily for 5 days and 300 mg/m2 mesna iv every 4 hr with three doses daily after IFX were given. In patients who had received prior radio...

journal_title：Gynecologic oncology

authors： Sutton GP,Blessing JA,DiSaia PJ,McGuire WP

更新日期：1993-04-01 00:00:00

abstract：OBJECTIVE:The purpose of this study was to examine the relationships between cyclooxygenase-2 (COX-2) expression and prognostic factors in cervical carcinomas. METHODS:We studied COX-2 expression in 53 women with cervical cancers, including 35 squamous cell carcinomas (SCCs), 1 adenosquamous cell carcinoma (ASCC), and...

journal_title：Gynecologic oncology

authors： Chen YJ,Wang LS,Wang PH,Lai CR,Yen MS,Ng HT,Yuan CC

更新日期：2003-03-01 00:00:00

abstract：:Elective oophorectomy at the time of hysterectomy for benign disease in women during their fifth decade is an important issue for both gynecologist and patient. It has been suggested that cancer developing in the residual ovary has a worse prognosis than the national average (L. McGowan, Obstet. Gynecol. 69, 386, 1987...

journal_title：Gynecologic oncology

authors： Fine BA,Yazigi R,Risser R

更新日期：1991-11-01 00:00:00

abstract：:The patient described synchronous mucinous tumors of the cervix and ovary and concurrent annular tubules, but without the classical stigmata of Peutz-Jeghers syndrome. The cervical tumor was an invasive mucinous adenocarcinoma with mixed components of minimal deviation and less-well-differentiated endometrioid morphol...

journal_title：Gynecologic oncology

authors： Matseoane S,Moscovic E,Williams S,Huang JC

更新日期：1991-12-01 00:00:00

abstract：:Previous herpes simplex virus type 2 (HSV-2) infections are known to predispose women for the development of cervical cancer, but causal relationship between the virus and the cancer has never been proven. Forty-six patients with cervical carcinoma (13 with preinvasive lesions and 33 with various stages of invasive di...

journal_title：Gynecologic oncology

authors： Vass-Sørensen M,Abeler V,Berle E,Pedersen B,Davy M,Thorsby E,Norrild B

更新日期：1984-07-01 00:00:00

abstract：:To test the association between cytotoxicity and in vitro cell cycle perturbations we systematically studied cell cycle perturbations after exposing human ovarian cancer cells to nine commonly used cytotoxic agents. Three principal patterns of cell cycle alterations were observed: a sequential S-G2/M block after expos...

journal_title：Gynecologic oncology

authors： Petru E,Sevin BU,Haas J,Ramos R,Perras J

更新日期：1995-07-01 00:00:00

abstract：OBJECTIVE:To compare the cost and perioperative outcomes of endometrial cancer staging when the procedure is performed by a gynecologic oncologist alone or when a general gynecologist participates in the procedure. METHODS:A retrospective analysis was performed on a series of women with clinical stage I endometrial ca...

journal_title：Gynecologic oncology

authors： Hoekstra A,Singh DK,Garb M,Arekapudi S,Rademaker A,Lurain JR

更新日期：2006-12-01 00:00:00

abstract：OBJECTIVES:To report the intermediate-term results of trans-abdominal ultrasound (TAUS)-guided brachytherapy in cervical cancer. MATERIALS AND METHODS:Ninety-two patients with cervical cancer (stage IB-IVA, according to FIGO staging), were treated by curative radiotherapy from February 2012 to June 2015. All patients ...

journal_title：Gynecologic oncology

authors： Tharavichitkul E,Chakrabandhu S,Klunklin P,Onchan W,Jia-Mahasap B,Wanwilairat S,Tippanya D,Jayasvasti R,Sripan P,Galalae RM,Chitapanarux I

更新日期：2018-03-01 00:00:00

abstract：OBJECTIVE:To determine whether squamous cervical cancers exhibit mutations or deletions in MHC class I genes or transport-associated protein (TAP) genes. METHODS:Polymerase chain reaction based protocols were used to examine HLA class I and TAP genes in a panel of cervical tumours, using DNA from corresponding blood s...

journal_title：Gynecologic oncology

authors： Fowler NL,Frazer IH

更新日期：2004-03-01 00:00:00

abstract：:Uterine papillary serous carcinoma (UPSC) is an aggressive histologic subtype of endometrial cancer. Currently, no effective chemotherapy regimens exist. We report a case of complete response of a stage IV UPSC to neoadjuvant chemotherapy with Taxol and carboplatin. ...

journal_title：Gynecologic oncology

authors： Le TD,Yamada SD,Rutgers JL,DiSaia PJ

更新日期：1999-06-01 00:00:00

abstract：OBJECTIVE:The value of surgical staging of apparent early stage epithelial ovarian carcinoma (EOC) is unclear. The aim of this study was to evaluate the importance of surgical staging on the stage of disease and treatment plan. MATERIAL AND METHODS:All patients with apparent stage I EOC undergoing staging from 01/01/2...

journal_title：Gynecologic oncology

authors： Hengeveld EM,Zusterzeel PLM,Lajer H,Høgdall CK,Rosendahl M

更新日期：2019-08-01 00:00:00

abstract：OBJECTIVE:The aim of this study was to evaluate clinical manifestations, management options, and prognosis for women presenting with gestational trophoblastic tumors with vaginal metastasis. METHOD:Fifty-one patients with vaginal metastases were analyzed retrospectively between January 1985 and September 2000. Vaginal...

journal_title：Gynecologic oncology

authors： Yingna S,Yang X,Xiuyu Y,Hongzhao S

更新日期：2002-03-01 00:00:00

abstract：OBJECTIVES:Laminin-5 is an attachment protein for epithelial cells. Several studies of a variety of cancers have reported increased expression of laminin-5 in carcinoma in situ and invasive cancer. This study was designed to investigate the correlation between the grade of cervical intraepithelial neoplasia and the imm...

journal_title：Gynecologic oncology

authors： Kohlberger P,Beneder Ch,Horvat R,Leodolter S,Breitenecker G

更新日期：2003-06-01 00:00:00

abstract：:All patients with bulky (> or =4 cm) Stage Ib or IIa cervical carcinoma treated at Chang Gung Memorial Hospital between August 1988 and December 1991 using a strategy of neoadjuvant chemotherapy with cisplatin, vincristine, and bleomycin and radical hysterectomy were reviewed. Fifty-nine evaluable patients received 1 ...

journal_title：Gynecologic oncology

authors： Lai CH,Hsueh S,Chang TC,Tseng CJ,Huang KG,Chou HH,Chen SM,Chang MF,Shum HC

更新日期：1997-03-01 00:00:00

abstract：OBJECTIVE:The aim of this study was to confirm a causal relationship between removal of circumflex iliac nodes to the distal external iliac nodes (CINDEIN) and lower-extremity lymphedema after systematic lymphadenectomy in patients with uterine corpus malignancies. METHODS:A retrospective chart review was carried out ...

journal_title：Gynecologic oncology

authors： Todo Y,Yamazaki H,Takeshita S,Ohba Y,Sudo S,Minobe S,Okamoto K,Kato H

更新日期：2015-10-01 00:00:00

abstract：OBJECTIVE:The consequences of defective homologous recombination and other DNA repair pathways are important in disease outcomes of numerous tumor types. The objective of this study was to explore BRCA1, PARP, FANCD2, PTEN, H2AX, and ATM protein expression in endometrial cancer (EC). METHODS:PARP1, γH2AX, ATM, FANCD2,...

journal_title：Gynecologic oncology

authors： Mhawech-Fauceglia P,Wang D,Kim G,Sharifian M,Chen X,Liu Q,Lin YG,Liu S,Pejovic T

更新日期：2014-03-01 00:00:00

abstract：OBJECTIVE:To investigate the influence of human anti-mouse antibodies (HAMA) on serial CA 125 measurements in serum of patients with epithelial ovarian cancer following single intraperitoneal (IP) therapy with Yttrium-90-labeled human milk fat globule 1 murine monoclonal antibody ((90)Y-muHMFG1) as part of a large inte...

journal_title：Gynecologic oncology

authors： Oei AL,Sweep FC,Massuger LF,Olthaar AJ,Thomas CM

更新日期：2008-05-01 00:00:00

abstract：:The cell line HTOA was established from a well-differentiated human ovarian serous cystadenocarcinoma. This line grew well and without interruption for 51 months and was subcultivated over 130 times. The cells were epithelial in shape, and neoplastic and pleomorphic features, a jigsaw puzzle-like arrangement, desmosom...

journal_title：Gynecologic oncology

authors： Ishiwata I,Ishiwata C,Soma M,Nozawa S,Ishikawa H

更新日期：1987-03-01 00:00:00